检索结果-南通市图书馆

Research progress on venous thrombosis development in patients with malignant tumors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第11期12卷 1900-1908页

作者： Teng-Fei Wang qian Chen Jie Deng Shi-Liang Li yuan Xu Si-Xing Ma Department of Vascular Surgery The Affiliated Hospital of Guizhou Medical UniversityGuiyang 550000Guizhou ProvinceChina Department of Organ Transplantation The Affiliated Hospital of Guizhou Medical UniversityGuiyang 550000Guizhou ProvinceChina

The coexistence of venous thromboembolism(VTE)within patients with cancer,known as cancer-associated thrombosis(CAT),stands as a prominent cause of mortality in this *** recent years,the incidence of VTE has demonstrated a steady increase across diverse tumor types,influenced by several factors such as patient management,tumor-specific risks,and treatment-related ***,mutations in specific genes have been identified as potential contributors to increased CAT occurrence in particular cancer *** conducted an extensive review encompassing pivotal historical and ongoing studies on *** review elucidates the risks,mechanisms,reliable markers,and risk assessment methodologies that can significantly guide effective interventions in clinical practice.

关键词： Malignant tumor Venous thromboembolism Cancer-associated thrombosis Research progress

pre-existing orthorhombic embryos-induced hexagonal-orthorhombic martensitic transformation in MnNiSi_(1-x)(CoNiGe)_x alloy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese physics B 2024年第4期33卷 691-699页

作者：张婷婷龚元元鲁子骞徐锋 MiiT Key Laboratory of Advanced Metallic and intermetallic Materials Technology School of Materials Science and EngineeringNanjing University of Science and TechnologyNanjing 210094China

The thermal-elastic martensitic transformation from high-temperature Ni_(2)in-type hexagonal structure to low-temperature TiNiSi-type orthorhombic structure has been widely studied in MnMX(M=Ni or Co,and X=Ge or Si)***,the answer to how the orthorhombic martensite nucleates and grows within the hexagonal parent is still *** this work,the hexagonal-orthorhombic martensitic transformation in a Co and Ge co-substituted MnNiSi is *** can find some orthorhombic laths embedded in the hexagonal parent at a temperature above the martensitic transformation start temperature(M_(s)).With the the sample cooing to M_(s),the laths turn broader,indicating that the martensitic transformation starts from these pre-existing orthorhombic *** observation suggests that these pre-existing orthorhombic laths do not originate from the hexagonal-orthorhombic martensitic transformation because of the difference between atomic occupations of doping elements in the hexagonal parent and those in the preexisting orthorhombic *** phenomenological crystallograp.ic theory and experimental investigations prove that the pre-existing orthorhombic lath and generated orthorhombic martensite have the same crystallography relationship to the hexagonal ***,the orthorhombic martensite can take these pre-existing laths as embryos and grow *** work imp.ies that the martensitic transformation in MnNiSi_(1-x)(CoNiGe)_(x) alloy is initiated by orthorhombic embryos.

关键词： martensitic transformation MnMX alloy orthorhombic embryo crystallography relationship

Characterization of distinct microbiota associated with androgenetic alopecia patients treated and untreated with platelet-rich plasma(pRp)

在线全文

学校读者我要写书评

暂无评论

Animal Models and Experimental Medicine 2024年第2期7卷 106-113页

作者： qian Zhang Yanan Wang Cheng Ran Yingmei Zhou Zigang Zhao Tianhua Xu Hongwei Hou yuan Lu Beijing Life Science Academy BeijingChina Department of pathology Affiliated Hospital of Hebei UniversityBaodingChina Department of Otolaryngology Affiliated Hospital of Hebei UniversityBaodingChina Department of Dermatology Huazhong University of Science and Technology Union Shenzhen HospitalShenzhenChina Department of Dermatology Hainan Hospital of PLA General HospitalSanyaChina Department of Chemical Engineering Tsinghua UniversityBeijingChina

Background:Androgenic alopecia(AGA)is the most common type of hair loss in men,and there are many studies on the treatment of hair loss by platelet-rich plasma(pRp).The human scalp contains a huge microbiome,but its role in the process of hair loss remains unclear,and the relationship between pRp and the microbiome needs further ***,the purpose of this study was to investigate the effect of pRp treatment on scalp microbiota ***:We performed pRp treatment on 14 patients with AGA,observed their clinical efficacy,and collected scalp swab samples before and after *** scalp microflora of AGA patients before and after treatment was characterized by amp.ifying the V3-V4 region of the 16 s RNA gene and sequencing for bacterial ***:The results showed that pRp was effective in the treatment of AGA patients,and the hair growth increased *** results of relative abundance analysis of microbiota showed that after treatment,g_Cutibacterium increased and g_Staphylococcus decreased,which played a stable role in scalp *** addition,g_Lawsonella decreased,indicating that the scalp oil production decreased after ***:The findings suggest that pRp may play a role in treating AGA through scalp microbiome rebalancing.

关键词： androgenic alopecia microbiome platelet-rich plasma scalp

imide-based covalent organic framework with excellent cyclability as an anode material for lithium-ion battery

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第6期35卷 206-210页

作者： Yue qian Zhoujia Liu Haixin Song Ruize Yin Hanni Yang Siyang Li Weiwei Xiong Saisai yuan Junhao Zhang Huan pang School of Environmental&Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China School of Chemistry&Chemical Engineering Yangzhou UniversityYangzhou 225009China Shandong Key Laboratory of Biochemical Analysis College of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042China

Covalent organic frameworks(COFs)exhibiting reversible redox behaviors have been identified as promising candidates for constructing electrode materials in lithium-ion batteries(LiBs).However,their extensive app.ication has been limited due to finite redox sites and poor structural *** this study,we design and synthesize a novel polyimide covalent organic framework(pi-COF)using the traditional solvothermal method and successfully apply it as an anode material for *** large conjugated structure of pi-COF accelerates charge transfer,while its large surface area provides more active sites,making pi-COF an attractive anode material for ***,the pi-COF anode material demonstrates high reversible specific capacity and excellent long-term cycling stability due to its COF ***,the pi-COF electrodes deliver a specific capacity of 800 m Ah/g at a current density of 200 m A/g after 200 cycles,while a specific capacity of 450 m Ah/g at a current density of 1000 m A/g is sustained after 800 *** outstanding lithium storage capacity,particularly the satisfactory long-term cycling stability,establishes pi-COF as a promising material for LiBs.

关键词： Ethylenediaminetetraacetic dianhydride Covalent organic frameworks polyimide Lithium-ion battery Anode material

Metformin:A promising clinical therapeutical approach for BpH treatment via inhibiting dysregulated steroid hormones-induced prostatic epithelial cells proliferation

在线全文

学校读者我要写书评

暂无评论

Journal of pharmaceutical Analysis 2024年第1期14卷 52-68页

作者： Tingting Yang Jiayu yuan Yuting peng Jiale pang Zhen Qiu Shangxiu Chen Yuhan Huang Zhenzhou Jiang Yilin Fan Junjie Liu Tao Wang Xueyan Zhou Sitong qian Jinfang Song Yi Xu qian Lu Xiaoxing Yin Jiangsu Key Laboratory of New Drug Research and Clinical pharmacy Xuzhou Medical UniversityXuzhouJiangsu221004China Department of pharmacy Affiliated Lianyungang Hospital of Xuzhou Medical UniversityLianyungangJiangsu222061China Department of pharmacy The Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu221006China New Drug Screening Center Jiangsu Center for Pharmacodynamics Research and EvaluationChina Pharmaceutical UniversityNanjing210009China School of Life Sciences University of EssexEssex CO43SQUnited Kingdom Department of Urology The Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu221006China Department of pharmacy Affiliated Hospital of Jiangnan UniversityWuxiJiangsu214000China

The occurrence of benign prostate hyperplasia(BpH)was related to disrupted sex steroid hormones,and metformin(Met)had a clinical response to sex steroid hormone-related gynaecological ***,whether Met exerts an antiproliferative effect on BpH via sex steroid hormones remains ***,our clinical study showed that along with prostatic epithelial cell(pEC)proliferation,sex steroid hormones were dysregulated in the serum and prostate of BpH *** the major contributor to dysregulated sex steroid hormones,elevated dihydrotestosterone(DHT)had a significant positive relationship with the clinical characteristics of BpH *** of adenosine 5'-monophosphate(AMp)-activated protein kinase(AMpK)by Met restored dysregulated sex steroid hormone homeostasis and exerted antiproliferative effects against DHT-induced proliferation by inhibiting the formation of androgen receptor(AR)-mediated Yes-associated protein(YAp1)-TEA domain transcrip.ion factor(TEAD4)***’s anti-proliferative effects were blocked by AMpK inhibitor or YAp1 overexpression in DHT-cultured BpH-1 *** findings indicated that Met would be a promising clinical therapeutic approach for BpH by inhibiting dysregulated steroid hormone-induced pEC proliferation.

关键词： Metformin Benign prostatic hyperplasia Sex steroid hormones homeostasis proliferation DHT YAp1-TEAD4 heterodimer

Oxidation behavior of 4774DD1 Ni-based single-crystal superalloy at 980℃ in air

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Foundry 2024年第2期21卷 116-124页

作者： Yu Fang Ya-zhou Li qiang Yang Qun-gong He Xiu-fang Gong qian Duan Hai-yang Song Fu Wang Qiong-yuan Zhang Hong Zeng State Key Laboratory of Long-Life High Temperature Materials Dongfang Turbine Co.Ltd.Deyang 618000SichuanChina State Key Laboratory for Manufacturing System Engineering School of Mechanical EngineeringXi’an Jiaotong UniversityXi’an 710049China

The oxidation behavior of a novel Ni-based single-crystal 4774DD1 superalloy for industrial gas turbine app.ications was investigated by the isothermal oxidation at 980℃ and discontinuous oxidation weight gain *** phase constitution and morphology of surface oxides and the characteristics of the crosssection oxide film were analyzed by XRD,SEM and *** show that the oxidation kinetics of the 4774DD1 superalloy follows the cubic law,indicating its weak oxidation resistance at this *** the oxidation time increases,the composition of the oxide film evolves as following:One layer consisting of a bottom Al_(2)O_(3)sublayer and an upper(Al_(2)O_(3)+NiO)mixture sublayer after oxidized for 25 ***,two layers composed of an outermost small NiO discontinuous grain layer and an internal layer for 75 *** internal layer is consisted of the bottom Al_(2)O_(3)sublayer,an intermediate narrow CrTaO_(4)sublayer,and an upper(Al_(2)O_(3)+NiO)mixture *** two layers comp.ising an outermost relative continuous NiO layer with large grain size and an internal layer as the oxidation time increases to 125 *** internal layer is composed of the upper(Al_(2)O_(3)+NiO)mixture sublayer,an intermediate continuous(CrTaO_(4)+NiWO_(4))mixture sublayer,and a bottom Al_(2)O_(3)***,three layers consisting of an outermost(NiAl2O_(4)+NiCr2O_(4))mixture layer,an intermediate(CrTaO_(4)+NiWO_(4))mixture layer,and a bottom Al_(2)O_(3)layer for 200 h.

关键词： nickel-base single crystal superalloy oxidation kinetics oxide film microstructure mechanism

Modulating the alloying mode in the doping-induced synthesis of Au-pd nanowires

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第4期17卷 3334-3343页

作者： Hui Jin Xiaoliang Wei Lecheng Zhao Jialong Yu Qiao pan Shumin Li qian Wang Zhaotong yuan Dan Yang Donghui Zhao Hongyu Chen Yawen Wang institute of Advanced Synthesis School of Chemistry and Molecular EngineeringJiangsu National Synergistic Innovation Center for Advanced MaterialsNanjing Tech UniversityNanjing 211816China School of Science Westlake UniversityHangzhou 310064China institute of Natural Sciences Westlake Institute for Advanced StudyHangzhou 310064China

Heterogeneous doping is one effective strategy for synthesizing metal alloy ***,the heterogeneous doping processes of pd on the ultrathin Au nanowires were systematically modulated and ***-pd alloy nanowires with various morphologies and lattice structures can be obtained by adjusting the morphology of the precursor Au nanowires and the kinetics of the heterogeneous doping *** effects of the rate of pd reduction and the concentration of the ligand oleylamine(OAm)on the pd deposition and alloying mode were ***,as the pd deposition rate decreases,the pd deposition and alloying mode switches from the island-forming Stransky–Krastanov(SK)mode to the epitaxial Frank-van der Merwe(FM)mode,and eventually to an unconventional twisting alloying mode,where the interdiffusion of pd and Au causes drastic rearrangement of the lattice structure and formation of helical *** kinetics-related variation of alloying mode could also be observed in the Au-Ag nanowires,demonstrating a general design p.inciple for the synthesis of alloy *** addition,the electrocatalytic performance of various Au-pd nanowires was evaluated,and the alloy nanowire formed via the SK mode was found to be an excellent electrocatalyst for oxygen reduction and ethanol oxidation.

关键词： gold nanowires Au-pd alloy oleylamine post-synthetic modification

predicting the Risk of Arterial Stiffness in Coal Miners Based on Different Machine Learning Models

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2024年第1期37卷 108-111页

作者： CHEN qian Wei HUANG Xue Zan DiNG Yu ZHU Feng Ren WANG Jia ZOU yuan Jie DU yuan Zhen ZHANG Ya Jun HUi Zi Wen ZHU Feng Lin MU Min The project was supported by Open Research Grant of Joint National-Local Engineering Research Centre for Safe and precise Coal Mining Anhui University of Science and TechnologyHefei 232001AnhuiChina School of public Health Anhui University of Science and TechnologyHefei 232001AnhuiChina Key Laboratory of industrial Dust prevention and Control Occupational Safety and HealthMinistry of EducationAnhui University of Science and TechnologyHefei 232001AnhuiChina Anhui institute of Occupational Safety and Health Anhui University of Science and TechnologyHefei 232001AnhuiChina Joint Research Center of Occupational Medicine and Health Institute of Grand HealthHefei Comprehensive National Science CenterAnhui University of Science and TechnologyHefei 232001AnhuiChina Department of Occupational&Environmental Health School of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030HubeiChina Key Laboratory of Environment and Health Ministry of Education&Ministry of Environmental Protectionand State Key Laboratory of Environmental Health(Incubating)School of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030HubeiChina

Coal is one of the world’s main energy resources,accounting for approximately 68%of China’s current total power ***,several studies have demonstrated that dust,exhaust fumes,and other harmful factors in coal mines increase the risk of cardiovascular disease(CVD)among miners^([1]).Arterial stiffness(AS)is an independent risk factor of CVD,and epidemiological studies have shown that AS plays a vital role in assessing the risk of CVD^([2]).

关键词： Arterial cardiovascular assessing

perpendicularly assembled oriented electrospinning nanofibers based piezoresistive pressure sensor with wide measurement range

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第7期17卷 6493-6501页

作者： Xiaoxue Bi Zhigang Duan Xiaojuan Hou Shuo qian Mengjiao yuan Jiajun Hu Jie Zhang Yuchen Lu Yanli Liu Jian He Zhiling peng Xiujian Chou School of Mechanical and Electrical Engineering North University of ChinaTaiyuan 030051China Science and Technology on Electronic Test and Measurement Laboratory North University of ChinaTaiyuan 030051China School of Software North University of ChinaTaiyuan 030051China School of information and Communication Engineering North University of ChinaTaiyuan 030051China

With the rapid development of wearable electronics,flexible pressure sensors have attracted wide attention in human–computer interaction and intelligent ***,it is a challenge to achieve a sensor with high sensitivity,wide measurement range,and wearing ***,we develop an oriented electrospinning thermoplastic polyurethane/polyacrylonitrile(TpU/pAN)nanofibers(OETpN)based piezoresistive pressure sensor(pONpS)in which the active layer and the electrode are assembled *** interdigital electrode is fabricated by spraying silver nanowires(AgNWs)on the OETpN through a mask *** active layer is composed of OETpN coated with MXene,encapsulated on the electrode by polyurethane(pU)*** porous structure of nanofibers membrane broadens the measurement range of the *** oriented nanofibers as active layer can improve the sensitivity in low pressure,because oriented nanofibers without interweaving nanofibers are more compressible than disordered *** prepared using the spraying method creates nanoscale microstructure and increases *** perpendicular assembly has greater response between the active layer and the electrode than the parallel assembly to improve the *** sensor exhibits high sensitivity(6.71 kpa^(−1),0.02–2 kpa)and wide measurement range(0.02–700 kpa).The sensor can detect weak signals such as radial artery.A pressure array constructed precisely represents the distribution of *** intelligent throat is created by combining machine learning algorithms with the *** can detect and recognize subtle throat vibrations while speaking,achieving recognition accuracy up to 100%using support vector machine(SVM)for five words with different *** fabricated sensor shows promising prospects in personal healthcare and intelligent robots.

关键词： oriented nanofibers perpendicular assembly parallel assembly intelligent throat machine learning algorithms