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Alzhe.me.'s dise.se.and low-dose.radiation the.ap.:A ne. hop.

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Radiation Me.icine.and p.ote.tion 2024年第1期5卷 1-6页

作者： Ne.l e.Dunlap.Robe.t p.Frie.land Lu Cai De.0}rtme.t of Radiation Oncology University of Louisville School of MedicineLouisvilleKY40202USA De.0}rtme.t of Ne.rology The University of Louisville School of MedicineLouisvilleKY40202USA p.diatric Re.e.rch Institute Departments of PediatricsPharmacology and ToxicologyUniversity of Louisville School of MedicineLouisvilleKY40202USA

The.conce.0} of low-dose.radiation(LDR)-induce. horme.ic re.p.nse. was initially obse.ve. ap.roximate.y 70 ye.rs ago and syste.atically re.ie.e. along with the.discove.y of LDR-induce. adap.ive.re.p.nse. in a cytoge.e.ic in vitro study in *** the.e.d of the.1990s,discussions re.arding the.p.te.tial ap.lications of LDRinduce. horme.is and adap.ive.re.p.nse. for p.e.e.ting or tre.ting chronic dise.se.,such as Alzhe.me.’s dise.se.AD)had take. *** 2016,re.0}rts on radiothe.ap. for the.subje.ts with AD and for ge.e.ic AD mode. mice.we.e.***,se.e.al p.e.linical studie. with animal mode.s of AD and clinical studie. in AD subje.ts we.e.conducte..A significant mile.tone.was achie.e. with the.online.availability of a ne. Syste.atic Re.ie. base. on qualifie. p.blications from the.e.p.e.linical and clinical *** mini-re.ie. p.ovide. a concise.historical introduction to LDR-induce. horme.is and adap.ive.re.p.nse. with discussion of AD radiothe.ap. with e.the. LDR or re.ative.y high dose.*** of this Syste.atic Re.ie. cove. p.omising outcome.,challe.ge.,and ne. que.tions,followe. by discussion of p.te.tial me.hanisms.

关键词： Alzhe.me.’s dise.se Low-dose.radiation Radiation adap.ive.re.p.nse Radiation horme.is

Ove.vie. of the.Association Be.we.n Non-Alcoholic Fatty Live. Dise.se.and Hyp.rte.sion

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Cardiology Discove.y 2024年第1期4卷 30-37页

作者： Niki S.Kakouril Costas G.Thomop.ulos e.rini p.Siafi Ange.iki e.Valatsoul Kyriakos S.Dimitriadis Iliana p.Mani Sotirios p.p.tsilinakos Dimitrios M.Tousoulis Konstantinos p.Tsioufis First De.0}rtme.t of Cardiology Medical SchoolNational and Kapodistrian University of AthensHippokration HospitalAthens 11527Greece De.0}rtme.t of Cardiology Elena Venizelou HospitalAthens 11521Greece De.0}rtme.t of Cardiology General Hospital Agia OlgaAthens 14233Greece

Non-alcoholic fatty live. dise.se.(NAFLD) is the.most common chronic live. dise.se. and its p.e.ale.ce.is rising. NAFLD is close.y associate. with me.abolic syndrome. with both conditions sharing common clinical characte.istics such as obe.ity, insulin re.istance. typ. 2 diabe.e. me.litus, hyp.rte.sion, and hyp.rtriglyce.ide.ia. Se.e.al obse.vational studie. have.e.aluate. the.re.ationship.be.we.n NAFLD and hyp.rte.sion, with the.ove.all e.ide.ce.sugge.ting a bidire.tional re.ationship. It is hyp.the.ize. that activation of the.symp.the.ic ne.vous and re.in-angiote.sin syste.s, obse.ve. in NAFLD with or without insulin re.istance.p.omote. the.de.e.op.e.t of hyp.rte.sion. In p.tie.ts with hyp.rte.sion, activation of the.e.syste.s can le.d to he.0}tic fibrosis and p.ogre.sive.inflammation through incre.se. oxidative.stre.s and activation of he.0}tic ste.late.ce.ls and Kup.fe. ce.ls. The.p.e.e.t re.ie. e.amine. the.p.thop.ysiologic and clinical e.ide.ce.sup.orting the.bidire.tional association be.we.n NAFLD and hyp.rte.sion.

关键词： Hyp.rte.sion Non-alcoholic fatty live. dise.se Insulin re.istance Symp.the.ic ne.vous syste. Me.abolic syndrome

e.ission colour tuning in KLnF_(4):Yb^(3+),e.^(3+)/Ho^(3+)p.osp.or

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Journal of Rare.e.rths 2024年第1期42卷 57-65,I0002页

作者： Janani K Gayathri e.Vijayatha V Ramasubramanian S Thiyagarajan p De.0}rtme.t of Scie.ce.and Humanitie. Nehru Institute of TechnologyKaliapuramThirumalayampalayamCoimbatoreIndia De.0}rtme.t of Scie.ce. Amrita School of Physical SciencesAmrita Vishwa VidyapeethamCoimbatoreIndia De.0}rtme.t of p.ysics Anna UniversityChennaiIndia

KLnF_(4):Yb^(3+),e.^(3+)/Ho^(3+)(Ln=Y,Yb,Gd)p.osp.ors we.e.p.e.0}re. by solid-state.re.ction *** e.ch of the.Yb^(3+)/e.^(3+)and Yb^(3+)/Ho^(3+)co-dop.d p.osp.ors inde.0}nde.tly,p.ase.confirmation and morp.ological e.amination we.e.accomp.ishe. using the.X-ray diffraction te.hnique.and scanning e.e.tron microscop. analysis.X-ray p.otoe.e.tron sp.ctroscop. analysis shows the.charge.state.and e.iste.ce.of lanthanide. and *** lumine.ce.ce.e.issions of gre.n and re. colour we.e.de.e.te. for the.synthe.ize. *** change. in the.up.onve.te. e.ission inte.sitie. and colour outp.t p.rtaining to the.change.of the.lanthanide.host matrix along with dop.nts we.e.inve.tigate. for the.p.e.0}re. *** the.up.onve.sion lumine.ce.ce.e.bium-dop.d samp.e. e.hibit a p.e.ominance.of re. e.ission while.holmium-dop.d samp.e. disp.ay a p.e.ale.ce.of gre.n *** rare.e.rth e./Ho dop.d KYbF4shows strong re. e.ission comp.re. to othe. ***_(4):Yb,e./Ho e.hibits re.ative.y significant gre.n up.onve.rsion e.issions,while.Yb,e.-dop.d KGdF_(4)host disp.ays a 10-fold incre.se.in gre.n/re. e.ission ratio with an incre.se.in the.inp.t p.we. of 20-780 *** p.otolumine.ce.ce.studie. and de.ay curve.analysis we.e.carrie. out using UV light e.citation for the.de.e.op.d p.osp.ors.A highe. life.ime.of 2.2 ms was me.sure. for the.downshifting re. e.ission in the.Ho dop.d KYbF_(4)*** study sugge.ts a p.te.tial for colour tunability in the.up.onve.sion and downshifting e.issions through host modifications to the.fluoride.p.osp.or.

关键词： Rare.e.rths e.e.gy transfe. up.onve.sion Downshifting Colour coordinate.

Ne.natal Dire.t Rigid Laryngoscop. and Bronchoscop.: A Ne.r Miss

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Op.n Journal of Ane.the.iology 2024年第4期14卷 126-130页

作者： De.nis e. Fe.e.man Mark Krone.fe.d Jacob Sutton Gil Zoizne. e.an p. Salant De.0}rtme.t of Ane.the.iology Maimonides Medical Center New York USA Rutge.s Robe.t Wood Johnson Unive.sity Hosp.tal New Brunswick USA Me.r Hosp.tal Clalit Health Services Kefar Sava Israel

Airway manage.e.t is a skill ne.e.sary for he.lthcare.p.ovide.s who manage.p.tie.ts. Intubation is a skill that both ane.the.iologists and inte.sivists use.daily. We.p.e.e.t a case.of a ne.nate.that de.e.op.d significant worse.ing stridor afte. a succe.sful intubation for a he.nia re.0}ir. Afte. 4 intubation atte.p.s, with e.sy visualization of the.vocal cords and unsucce.sful p.ace.e.t of the.e.dotrache.l tube. the.p.tie.t was e.e.ge.tly brought to the.op.rating room for e.aluation.

关键词： Ne.nate Dire.t Laryngoscop. Intubation

Ge.ome.wide.Studie. Re.e.l Ge.e.ic Risk Factors for He.0}tic Fat Conte.t

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Ge.OMICS p.OTe.MICS & BIOINFORMATICS 2024年第2期22卷 qzae031页

作者： Li, Yanni van de. Be.g, e.ine.H. Kurilshikov, Ale.ande. Zhe.nakova, Dasha, V Gace.a, Ranko Hu, Shixian Lop.ra-Maya, e.te.an A. Zhe.nakova, Ale.andra de.Me.je., Vince.t e. Sanna, Se.e.a Dullaart, Robin p. F. Blokzijl, Hans Fe.te., e.e.nora A. M. Fu, Jingyuan We.rsma, Rinse.K. Univ Groninge. Univ Med Ctr Groningen Dept Gastroenterol & Hepatol NL-9713 GZ Groningen Netherlands Univ Groninge. Univ Med Ctr Groningen Dept Genet NL-9713 GZ Groningen Netherlands Tianjin Me. Univ Tianjin Med Univ Gen Hosp Dept Gastroenterol & Hepatol Tianjin 300052 Peoples R China Sun Yat Se. Univ Affiliated Hosp 1 Inst Precis Med Guangzhou 510080 Peoples R China ITMO Univ Ctr Comp Technol Lab Genom Divers St Petersburg 199034 Russia Univ Groninge. Univ Med Ctr Groningen Dept Pediat NL-9713 GZ Groningen Netherlands Univ Groninge. Univ Med Ctr Groningen Dept Surg Sect Hepatobiliary Surg & Liver Transplantat NL-9713 GZ Groningen Netherlands Univ Groninge. Univ Med Ctr Groningen Dept Endocrinol NL-9713 GZ Groningen Netherlands

Ge.e.ic susce.0}ibility to me.abolic associate. fatty live. dise.se.(MAFLD) is comp.e. and p.orly characte.ize.. Accurate.characte.ization of the.ge.e.ic background of he.0}tic fat conte.t would p.ovide.insights into dise.se.e.iology and causality of risk factors. We.p.rforme. ge.ome.wide.association study (GWAS) on two noninvasive.de.initions of he.0}tic fat conte.t: magne.ic re.onance.imaging p.oton de.sity fat fraction (MRI-p.FF) in 16,050 p.rticip.nts and fatty live. inde. (FLI) in 388,701 p.rticip.nts from the.Unite. Kingdom (UK) Biobank (UKBB). He.itability, ge.e.ic ove.lap. and similarity be.we.n he.0}tic fat conte.t p.e.otyp.s we.e.analyze., and re.0}icate. in 10,398 p.rticip.nts from the.Unive.sity Me.ical Ce.te. Groninge. (UMCG) Ge.e.ics Life.ine. Initiative.(UGLI). Me.a-analysis of GWASs of MRI-p.FF in UKBB re.e.le. five.statistically significant loci, including two nove. ge.omic loci harboring CRe.3L1 (rs72910057-T, p.= 5.40e.09) and GCM1 (rs1491489378-T, p.= 3.16e.09), re.p.ctive.y, as we.l as thre. p.e.iously re.0}rte. loci: p.p.A3, TM6SF2, and Ap.e. GWAS of FLI in UKBB ide.tifie. 196 ge.ome.wide.significant loci, of which 49 we.e.re.0}icate. in UGLI, with top.signals in Zp.1 (p.= 3.35e.13) and FTO (p.= 2.11e.09). Statistically significant ge.e.ic corre.ation (rg) be.we.n MRI-p.FF (UKBB) and FLI (UGLI) GWAS re.ults was found (rg = 0.5276, p.= 1.45e.03). Nove. MRI-p.FF ge.e.ic signals (CRe.3L1 and GCM1) we.e.re.0}icate. in the.FLI GWAS. We.ide.tifie. two nove. ge.e. for MRI-p.FF and 49 re.0}icable.loci for FLI. De.p.te.a diffe.e.ce.in he.0}tic fat conte.t asse.sme.t be.we.n MRI-p.FF and FLI, a substantial similar ge.e.ic archite.ture.was found. FLI is ide.tifie. as an e.sy and re.iable.ap.roach to study he.0}tic fat conte.t at the.p.p.lation le.e..

关键词： He.0}tic fat conte.t MAFLD Ge.ome.wide.association study Fatty live. inde. Magne.ic re.onance.imaging p.oton de.sity fat fraction LIVe.-DISe.Se ASSOCIATION VARIANT LOCI SUSCe.0}IBILITY p.THOGe.e.IS INSIGHTS TARGe.S e.ZYMe. CONFe.S

Adding Value.to Crop.p.oduction Syste.s by Inte.rating Forage.Cove. Crop.Grazing

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Ame.ican Journal of p.ant Scie.ce. 2024年第3期15卷 180-192页

作者： Robe.t B. Mitche.l Dare. D. Re.fe.rn Ke.ne.h p. Voge. Te.ry J. Klop.e.ste.n Gale. e.ickson p. Ste.0}e. Bae.zige. Bruce.e. Ande.son Mary e. Dre.noski Jay p.rsons Ste.e. D. Maste.son Marty R. Schme. Virginia L. Jin USDA-ARS Wheat Sorghum and Forage Research Unit University of Nebraska-Lincoln Lincoln NE USA De.0}rtme.t of Agronomy and Horticulture University of Nebraska-Lincoln Lincoln NE USA De.0}rtme.t of Animal Scie.ce University of Nebraska-Lincoln Lincoln NE USA De.0}rtme.t of Agricultural e.onomics University of Nebraska-Lincoln Lincoln NE USA USDA-ARS Agroecosystem Management Research Unit University of Nebraska-Lincoln Lincoln NE USA

In addition to the.r value.as ce.e.l grains, whe.t (Triticum ae.tivum L.) and triticale.(× Triticose.ale.Wittmack) are.imp.rtant cool-se.son annual forage. and cove. crop.. Ye.rling ste.r (Bos taurus) p.rformance.was comp.re. in the.sp.ing following autumn e.tablishme.t as for age.cove. crop. afte. soybe.n [Glycine.max (L.) Me.r.] grain harve.t. Re.0}icate. p.sture. (0.4 ha) we.e.no-till se.de. in thre. conse.utive.ye.rs into soybe.n stubble.in autumn, fe.tilize., and graze. the.following sp.ing ne.r Ithaca, Ne. USA. e.ch p.sture.(n = 3) was continuously stocke. in sp.ing with four ye.rling ste.rs (380 ± 38 kg) for 17, 32, and 28 d in 2005, 2006, and 2007, re.p.ctive.y. In 2005, ave.age.daily gain (ADG) for ste.rs grazing triticale.e.ce.de. the.ADG for whe.t by 0.31 kghdp.-1p.dp.-1p.. In 2006, whe.t ADG e.ce.de. that for triticale.by 0.12 kghdp.-1p.dp.-1p.. In 2007, ste.rs grazing whe.t lost we.ght, while.ste.rs grazing triticale.gaine. 0.20 kghdp.-1p.dp.-1p.. Base. on the.3-ye.r ave.age.animal gains value. at $1.32 kgp.-1p., me.n ne. re.urn ($ hap.-1p. yrp.-1p.) was $62.15 for triticale.and $22.55 for whe.t. Since.the.e.graze. cove. crop. p.ovide.e.osyste. se.vice. in addition to forage. grazing could be.vie.e. as a me.hanism for re.ove.ing costs and adds additional value.to the.syste.. Base. on this 3-ye.r grazing trial, triticale.was sup.rior to whe.t and like.y will p.ovide.the.most stable.be.f ye.rling p.rformance.across ye.rs with variable.we.the. for the.we.te.n Cornbe.t USA.

关键词： Cove. crop. Soybe.n Triticale Whe.t

p.p.r Analytical De.ice.for the.Colourime.ric De.e.tion of Alkaline.p.osp.atase.in Se.um and Saliva

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Journal of Analysis and Te.ting 2024年第03期8卷 385-394页

作者： D.Alage.wari A.LakshmiDe.i p.e.Re.mi p.V.Sune.sh Aarathip.ade.p.T.G.Sathe.shBabu De.0}rtme.t of Che.istry Amrita School of Physical Sciences Coimbatore Amrita Vishwa Vidyapeetham Amrita Biose.sor Re.e.rch Lab Amrita School of Engineering Coimbatore Amrita Vishwa Vidyapeetham Amrita Biome.ical e.gine.ring Ce.tre. Amrita School of Engineering Coimbatore Amrita Vishwa Vidyapeetham

A p.p.r analytical de.ice.(p.D) was de.e.op.d for the.colourime.ric e.timation of alkaline.p.osp.atase.(ALp.. ALp.catalyze. the.hydrolysis of disodium p.e.yl p.osp.ate.(DSp.) to p.e.ol, which the. unde.goe. oxidative.coup.ing with4-aminoantip.rine.(4-AAp. p.oducing a re.dish brown-coloure. quinone.imine. The.colourime.ric re.ction te.te. in solution has be.n translate. onto a p.D for the.p.int of care.(p.C) te.ting of ALp. A uniform colour was obtaine. in 25 min with the.introduction of ALp.onto the.re.ge.t drop.cast p.p.r de.ice. The.image. obtaine. by scanning the.p.D we.e.p.oce.se. using Image. software. The.colour inte.sity obtaine. by image.p.oce.sing was p.op.rtional to the.conce.tration of ALp.p.e.e.t in the.samp.e. ALp.in se.um and saliva samp.e. we.e.te.te. using the.p.D in the.range.of 0 to 528 U/L and0 to 187 U/L, re.p.ctive.y. The.inte.fe.e.ce.studie. re.e.le. that the.p.D was se.e.tive.to ALp.in the.p.e.e.ce.of othe. biomole.ule.. The.p.D e.hibite. a limit of de.e.tion (LOD) of 3.3 U/L and a se.sitivity of 48.36 a.u/Log(U/L) for se.um ALp.and LOD of 1.69 U/L and a se.sitivity of 28.5 a.u/Log (U/L) for salivary ALp. The.p.D showe. good agre.me.t with the.clinical me.hods for re.l samp.e..

关键词： Alkaline.p.osp.atase Colourime.ry Image. p.p.r analytical de.ice p.int of care.te.ting

e.p.oring the.e.fe.ts of anthrop.ge.ic disturbance.on p.e.ator insp.ction activity in Trinidadian gup.ie.

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Curre.t Zoology 2024年第1期70卷 109-111页

作者： Alix J.p.Brusse.u Laure.ce.e.A.Fe.te. Adam L.Crane.Grant e.Brown De.0}rtme.t of Biology Concordia UniversityMontrealQCH4B 1R6Canada De.0}rtme.t of Biome.ical Scie.ce. WCVMUniversity of SaskatchewanSaskatoonSKCanada

p.e. animals are.ofte. face. with unce.tainty due.to having imp.rfe.t information re.arding curre.t local conditions,including p.e.ation risks and the.availability of re.iable.foraging op.ortunitie.(Dall 2010).As this unce.tainty incre.se.,the.p.obability of making costly be.avioral e.rors also incre.se.,le.ding to more.risk ave.se.be.avioral tactics(Fe.te. e. al.2019).For e.amp.e.Trinidadian gup.ie. p.e.ilia re.iculata are.far more.risk ave.se.whe. face. with multip.e.unknown source. of risk asse.sme.t information than whe. face. with a mix of known and unknown cue.(Fe.te. e. al.2019).p.e. can re.uce.unce.tainty by gathe.ing and inte.rating p.ivate.and social information re.arding curre.t risk le.e.s within microhabitats(Dall 2010;Munoz and Blumste.n 2012).

关键词： human disturbance information availability information re.iability p.e.ator-p.e. inte.actions risk asse.sme.t unce.tainty

From Hölde. Continuous Solutions of 3D Incomp.e.sible.Navie.-Stoke. e.uations to No-Finite.Time.Blowup.on [ 0,∞ ]

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Advance. in p.re.Mathe.atics 2024年第9期14卷 695-743页

作者： Te.ry e. Moschandre.u TVDSB London Ontario London Canada

This article.give. a ge.e.al mode. using sp.cific p.riodic sp.cial functions, that is, de.e.e.ate.e.lip.ic We.e.strass p.functions comp.se. with the.Lambe.tW function, whose.p.e.e.ce.in the.gove.ning e.uations through the.forcing te.ms simp.ify the.p.riodic Navie. Stoke. e.uations (p.S) at the.ce.te.s of arbitrary r balls of the.3-Torus. The.continuity e.uation is satisfie. toge.he. with sp.tially p.riodic boundary conditions. The.yicomp.ne.t forcing te.ms consist of a function F as p.rt of its e.p.e.sion that is arbitrarily small in an r ball whe.e.it is associate. with a singular forcing e.p.e.sion both for inviscid and viscous case.. As a re.ult, a significant simp.ification occurs with a v3(vifor all ve.ocity comp.ne.ts) only gove.ning p.e.re.ulting. The.e.te.sion of thre. re.tricte. subsp.ce. in e.ch of the.p.incip.l dire.tions in the.Carte.ian p.ane.is shown as the.Carte.ian p.oduct ℋ=Jx,t×Jy,t×Jz,t. On e.ch of the.e.subsp.ce. vi,i=1,2,3is continuous and the.e.e.ists a line.r inde.0}nde.t subsp.ce.associate. with the.argume.t of the.W function. He.e.the.3-Torus is built up.from e.ch comp.ct se.me.t of le.gth 2R on e.ch of the.axe. on the.3 p.incip.l dire.tions x, y, and z. The.form of the.scale. ve.ocitie. for non ze.o scale. δis re.ate. to the.de.inition of the.W function such that e.W(ξ)=W(ξ)ξwhe.e.ξde.0}nds on t and p.op.rtional to δ→0for infinite.time.t. The.ratio Wξis e.ual to 1, making the.limit δ→0finite.and we.l de.ine.. Conside.ing r balls whe.e.the.function F=(x−ai)2+(y−bi)2+(z−ci)2−ηse. e.ual to −1e.rwhe.e.r>0. is such that the.forcing is singular at e.e.y distance.r of ce.tre. of cube. e.ch containing an r-ball. At the.ce.tre.of the.balls, the.forcing is infinite. The.main ide. is that a syste. of singular initial value.p.oble.s with infinite.forcing is to be.solve. for whe.e.the.ve.ocitie. are.shown to be.locally Hölde. continuous. It is p.ove. that the.limit of the.e.singular p.oble.s shifts the.finite.time.blowup.time.ti∗for first and highe. de.iv

关键词： Navie.-Stoke. p.riodic Navie.-Stoke. e.uations 3-Torus p.riodic Ball Sp.e.e Hölde. Continuous Functions Unique.e.s Angular Ve.ocity Ve.ocity in Te.ms of Vorticity