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Follicle stimulating hormone controls granulosa cell glutamine synthesis to regulate ovulation

Protein & Cell 2024年第7期15卷 512-529页

作者： Kai-Hui Zhang Fei-Fei Zhang Zhi-Ling Zhang Ke-Fei Fang Wen-Xing Sun Na Kong Min Wu Hai-ou liu Yan liu Zhi Li Qing-Qing Cai Yang Wang Quan-Wei Wei Peng-Cheng Lin Yan Lin Wei Xu Cong-Jian Xu Yi-Yuan Yuan Shi-Min Zhao The Obstetrics&Gynecology Hospital of Fudan University State Key Laboratory of Genetic EngineeringFudan UniversityShanghai 200090China Shanghai Key Laboratory of Metabolic Remodeling and Children’s Hospital of Fudan UniversityShanghai 200032China School of Life Sciences and Institutes of Biomedical Sciences Fudan UniversityShanghai 200438China Department of Nutrition and Food Hygiene School of Public HealthNantong UniversityNantong 226019China Reproductive Medicine Center The Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008China Shanghai Fifth People’s Hospital of Fudan University Fudan UniversityShanghai 200240China Department of Animal Science and Technology Nanjing Agricultural UniversityNanjing 210014China Key Laboratory for Tibet Plateau Phytochemistry of Qinghai Province College of PharmacyQinghai University for NationalitiesXining 810007China Pediatric Research Institute Children’s Hospital Affiliated to Shandong University(Jinan Children’s Hospital)Jinan 250022China

Polycystic ovary syndrome(PCOS)is the leading cause of anovulatory *** understanding of the ovulation drivers hinders PCOS ***,we report that follicle stimulating hormone(FSH)controls follicular fluid(FF)glutamine levels to determine *** ovulation starts from FF-exposing granulosa cell(GC)*** glutamine,which decreases in pre-ovulation porcine FF,elevates in PCOS patients ***-glutamine chow to elevate FF glutamine inhibits mouse GC apoptosis and induces hormonal,metabolic,and morphologic PCOS ***,follicle-development-driving FSH promotes GC glutamine synthesis to elevate FF glutamine,which maintain follicle wall integrity by inhibiting GC apoptosis through inactivating ASK1-JNK apoptotic *** and glutamine inhibit the rapture of cultured murine *** removal or ASK1-JNK pathway activation with metformin or AT-101 reversed PCOS traits in PCOS models that are induced with either glutamine or *** suggest that glutamine,FSH,and ASK1-JNK pathway are targetable to alleviate PCOS.

关键词： ovulation glutamine granulosa cells PCOS FSH

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考虑船间效应和操纵性能的内河船舶追越风险模型及应用

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中国航海 2024年第1期47卷 1-8,17页

作者：刘欧宋国宾袁小亮吴兵武汉理工大学水路交通控制全国重点实验室湖北武汉430063 武汉理工大学交通与物流工程学院湖北武汉430063 日照引航站山东日照276800 中华人民共和国泉州海事局福建泉州362014 武汉理工大学智能交通系统研究中心湖北武汉430063 武汉理工大学国家水运安全工程技术研究中心湖北武汉430063 广东省内河港航产业研究有限公司广东韶关512000

针对内河在航船舶追越过程中碰撞事故频发的问题,构建考虑船间效应和操纵性能的内河船舶追越风险模型。对内河在航船舶追越过程进行情景分析,从纵向和横向距离两个方面综合考虑船舶追越风险。引入船舶纵向安全距离模型和紧急转舵距离,... 详细信息

针对内河在航船舶追越过程中碰撞事故频发的问题,构建考虑船间效应和操纵性能的内河船舶追越风险模型。对内河在航船舶追越过程进行情景分析,从纵向和横向距离两个方面综合考虑船舶追越风险。引入船舶纵向安全距离模型和紧急转舵距离,提出不同危险局面下的纵向距离计算方法。考虑船间效应和船舶保向性,根据力和力矩方程,提出不同会遇时刻的横向距离计算方法。构建基于模糊逻辑的内河船舶追越风险模型,选取100组长江典型追越案例验证模型的可行性。

关键词：水路运输船舶碰撞船舶操纵性能船间效应追越风险

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Density-based rough set model for hesitant node clustering in overlapping community detection

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Journal of Systems Engineering and Electronics 2014年第6期25卷 1089-1097页

作者： Jun Wang Jiaxu Peng ou liu School of Economics and Management Beihang University School of Accounting and Finance The Hong Kong Polytechnic University

Overlapping community detection in a network is a challenging issue which attracts lots of attention in recent years.A notion of hesitant node（HN） is proposed. An HN contacts with multiple communities while the communications are not strong or even accidental, thus the HN holds an implicit community ***, HNs are not rare in the real world network. It is important to identify them because they can be efficient hubs which form the overlapping portions of communities or simple attached nodes to some communities. Current approaches have difficulties in identifying and clustering HNs. A density-based rough set model（DBRSM） is proposed by combining the virtue of densitybased algorithms and rough set models. It incorporates the macro perspective of the community structure of the whole network and the micro perspective of the local information held by HNs, which would facilitate the further ＂growth＂ of HNs in community. We offer a theoretical support for this model from the point of strength of the trust path. The experiments on the real-world and synthetic datasets show the practical significance of analyzing and clustering the HNs based on DBRSM. Besides, the clustering based on DBRSM promotes the modularity optimization.

关键词： density-based rough set model(DBRSM) overlapping community detection rough set hesitant node(HN) trust path

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Simulation of turbulent combustion in DLR Scramjet

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第7期8卷 1053-1058页

作者： Zou Jian-feng ZHENG Yao liu ou-zi School of Aeronautics and Astronautics Zhejiang University Hangzhou 310027 China

Turbulent combustion in a DLR (German Aerospace Center) Scramjet engine was simulated using the newly-proposed Partially Resolved Numerical Simulation (PRNS) procedure. The PRNS procedure uses temporal filtering to define large-scale turbulence, and the model developed to account for unresolved scales is grid independent. No problem about inner commutation error and inconsistencies will arise from the PRNS, while such issues are of concern in traditional Large Eddy Simulation (LES) methods. The mean results have good agreement with the experiment data and the flow structures with small scales are well resolved.

关键词： Scramjet Turbulent combustion Unstructured grid Finite volume method

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Numerical and Experimental Investigation into Plane Charge Explosion Technique

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Transactions of Tianjin University 2006年第B09期12卷 51-55页

作者： ZHANG Yadong liu ou FANG Qin XIANG Hengbo Engineering Institute of Engineering Corps PLA University of Science and Technology Nanjing 210007 China

Plane charge explosion technique (PCET) is one of the major techniques frequently used in large-scale blast-resistant structure tests. An FEM model was established, which can simulate the process of air releasing from the blast cavity. The effects of the charge density, the interval of the charge strip, the distance of the charges from the structure, and the mass of backfill soil on the overpressures applied on the tested structures were analyzed by the FEM model. The quantitative relationships between the peak value and the duration of the overpressure and the above-mentioned affecting parameters were established. Agreement between numerical results and the test data was obtained.

关键词： plane charge explosion technique blast wave numerical simulation LS-DYNA

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新型二氧化碳化学吸收剂研究进展

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现代化工 2024年第7期44卷 51-56页

作者：王大勇谷小虎刘欧阳林雄超方梦祥河南神马氢化学有限责任公司河南平顶山467000 炼焦煤资源绿色开发全国重点实验室中国平煤神马集团河南平顶山467000 中国矿业大学(北京)化学与环境工程学院北京100083 浙江大学能源清洁利用国家重点实验室浙江杭州310027

介绍了新型二氧化碳化学吸收剂的研究进展,主要包括相变吸收剂、离子液体吸收剂、低共熔溶剂、非水吸收剂和催化解析,指出相变吸收剂吸收能力强,但解析能耗高,并存在一定的腐蚀性;离子液体吸收剂具有低挥发性、高化学稳定性、可调控性... 详细信息

介绍了新型二氧化碳化学吸收剂的研究进展,主要包括相变吸收剂、离子液体吸收剂、低共熔溶剂、非水吸收剂和催化解析,指出相变吸收剂吸收能力强,但解析能耗高,并存在一定的腐蚀性;离子液体吸收剂具有低挥发性、高化学稳定性、可调控性等优点,但存在合成复杂、成本高、黏度大等缺点;低共熔溶剂蒸汽压极低、溶解性能好、结构和性质具有可调性,黏度低,但是吸收量低,不适应低浓度二氧化碳场景;非水吸收剂具有腐蚀性低、解析能耗低,但无法管道输送,成本高;还可以在吸收剂中调控催化体系,可快速诱导吸收溶剂再生,降低再生能耗,但催化剂稳定性有待进一步加强。最后提出未来二氧化碳化学吸收剂可通过精细地分子设计和合成、引入新的功能基团,制备出成本更低、环境影响更小、吸收性能更强和热稳定性佳、再生能耗低的产品。

关键词：二氧化碳化学吸收法相变吸收剂离子液体吸收剂低共熔溶剂非水吸收剂

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Pixel-level crack segmentation of tunnel lining segments based on an encoder–decoder network

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Frontiers of Structural and Civil Engineering 2024年第5期18卷 681-698页

作者： Shaokang Hou Zhigang ou Yuequn HUANG Yaoru liu State Key Laboratory of Hydroscience and Engineering Tsinghua UniversityBeijing 100084China China Renewable Energy Engineering Institute Beijing 100120China State Key Laboratory of Stimulation and Regulation of Water Cycles in River Basins China Institute of Water Resources and Hydropower ResearchBeijing 100038China Hunan Provincial Water Resources Development&Investment Co. Ltd.Changsha 410007China

Regular detection and repair for lining cracks are necessary to guarantee the safety and stability of *** development of computer vision has greatly promoted structural health *** study proposes a novel encoder–decoder structure,CrackRecNet,for semantic segmentation of lining segment cracks by integrating improved VGG-19 into the U-Net *** image acquisition equipment is designed based on a camera,3-dimensional printing(3DP)bracket and two laser rangefinders.A tunnel concrete structure crack(TCSC)image data set,containing images collected from a double-shield tunnel boring machines(TBM)tunnel in China,was *** data preprocessing operations,such as brightness adjustment,pixel resolution adjustment,flipping,splitting and annotation,2880 image samples with pixel resolution of 448×448 were *** model was implemented by Pytorch in PyCharm processed with 4 NVIDIA TITAN V *** the experiments,the proposed CrackRecNet showed better prediction performance than U-Net,TernausNet,and *** paper also discusses GPU parallel acceleration effect and the crack maximum width quantification.

关键词： tunnel lining segment crack detection semantic segmentation convolutional neural network encoder-decoder structure

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Effect of surface free energy of acetylene black powder on air electrode performance

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Rare Metals 2006年第z1期25卷 364-368页

作者： ou Xiuqin liu Shuguang LIANG Guangchuan LI Ying ZHI Xiaoke HAN Bin Institute of Power and Ecomaterial Science Hebei University of TechnologyTianjin 300130China

The effects of acetylene black powder surface free energy on air electrode electrochemical performance and lifetime were *** acetylene black was immersed in 30%H_(2)O_(2)at room temperature and the changes of functional groups and surface free energy were investigated by X-ray Photoelectron Spectroscopy(XPS)and powder contact angle(CA).The air electrode performance was characterized by the potential polarization curves and the lifetime was measured by constant-current *** shows that,its surface free energy is the lowest when the acetylene black is immersed in H_(2)O_(2)for 240 *** polarization potential of the air electrode prepared by the pretreated acetylene black is 0.25 V(***/HgO),0.21 V lower than the air electrode with untreated acetylene black when the working current density is 100 mA·cm^(-1).And its lifetime is over 800 h at 80 mA·cm^(-1).The pretreatment of acetylene black for proper time by H_(2)O_(2)is favorable for the stability of the tri-phase reaction interface of air electrode and improvement of its performance.

关键词： air electrode acetylene black immerse surface free energy electrochemical performance

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Magnetic properties of tin-doped ferrites nanoparticles Sn_xFe_(3-x)O_4

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Rare Metals 2006年第z1期25卷 493-497页

作者： LU Yanwu ou Yiyu liu Fangxin Department of Physics Beijing Jiaotong University Beijing 100044 China Department of Physics Beijing Jiaotong University Beijing 100044 China Department of Astronomy and Applied Physics University of Science & Technology of China Hefei 230026 China

Nanoparticles of tin-doped ferrites SnxFe3-xO4 (x=0, 0.1, 0.2, 0.3, 0.4, 1.0) were prepared by the precipitation exchange method. The particles of all specimens are crystalline with mean diameter in the range of 4-8 nm, and the lattice parameters enlarge with increasing tin content. Magnetization and Mssbauer data indicate that the specimens are paramagnetic. The saturation magnetization decreases, as well as the magnetization and the coercive field increase, with increasing tin-content, the possible causes of which were discussed.

关键词： tin-doped ferrite quantum composition article-size effect paramagnetic properties

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Numerical analysis of geosynthetic-reinforced embankment performance under moving loads

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第2期16卷 682-696页

作者： Xuanming Ding Jinqiao Zhao Qiang ou Jianfei liu College of Civil Engineering Chongqing UniversityChongqing400045China Key Laboratory of New Technology for Construction of Cities in Mountain Area Chongqing UniversityChongqing400045China China United Engineering Corporation Limited Hangzhou310052China

The performance of geosynthetic-reinforced embankments under traffic moving loads is always a hotspot in the geotechnical engineering field.A three-dimensional(3D)model of a geosynthetic-reinforced embankment without drainage consolidation was established using the finite element software *** this model,the traffic loads were simulated by two moving loads of rectangular pattern,and their amplitude,range,and moving speed were realized by a Fortran *** embankment fill was simulated by an equivalent linear viscoelastic model,which can reflect its *** geogrid was simulated by the truss element,and the geocell was simulated by the membrane *** elements were utilized to weaken the boundary effect caused by the model geometry at the *** of the established numerical model was conducted by comparing the predicted deformations in the cross-section of the geosynthetic-reinforced embankment with those from the existing *** this basis,the dynamic stress and strain distribution in the pavement structure layer of the geosynthetic-reinforced embankment under a moving load was also ***,a parametric study was conducted to examine the influences of the different types of reinforcement,overload,and the moving load velocity on the geosynthetic-reinforced embankment.

关键词： Geosynthetic-reinforced layer Numerical model Moving load Embankment Deformation Stress

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