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The Clinical Value of Syntax Scores in Predicting Coronary Artery Disease Outcomes

Cardiovascular Innovations and Applications 2022年第2期6卷 197-208页

作者： Lutfu Askin okan tanriverdi Department of Cardiology Adiyaman Education and Research HospitalAdiyamanTurkey

The Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery(SYNTAX)score(SS)has signiﬁcantly improved angiographic risk stratiﬁ*** analyzing angiographic variables,this score characterizes coronary artery disease qualitatively and *** date,combining this score with other non-angiographic clini-cal scores has broadened perspectives regarding risk estimation,and future research on this topic appears promising.

关键词： coronary artery disease risk stratiﬁcation SS risk estimation non-angiographic clinical scores

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Associations between Vaspin Levels and Coronary Artery Disease

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Cardiovascular Innovations and Applications 2020年第1期4卷 211-216页

作者： Lutfu Askin okan tanriverdi Hakan Tibilli Serdar Turkmen Department of Cardiology Adiyaman Education and Research HospitalAdiyamanTurkey

The relationship between serum vaspin levels and metabolic or coronary artery disease is currently of interest for *** adipokine concentrations have been shown to be increased signifi cantly in atherosclerotic lesions,the role adipokines in the atherosclerotic process remains to be *** is a new biological marker associated with obesity and impaired insulin *** vaspin concentration has been shown to correlate with the severity of coronary artery *** infl ammation triggered by vaspin inhibits atherogenesis by suppressing macrophage foam cell formation and vascular smooth muscle cell migration and *** also contributes to plaque stabilization by increasing collagen content and reducing the intraplaque macrophage to vascular smooth muscle cell *** therapeutic goal concerning vaspin is to fi ght atherosclerosis and related diseases,as well as to maintain vascular health.

关键词： adipokine atherosclerosis infl ammation coronary artery disease vaspin

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Serum Irisin:Pathogenesis and Clinical Research in Cardiovascular Diseases

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Cardiovascular Innovations and Applications 2020年第1期4卷 195-200页

作者： Lutfu Askin Kader Eliz Uze okan tanriverdi Serdar Turkmen Department of Cardiology Adiyaman Education and Research HospitalAdiyamanTurkey

Recently,muscular function/dysfunction has gained importance in the maintenance of metabolic homeostasis in cardiovascular *** muscle plays a vital role in coordinating the activity and metabolism of endocrine organs by secreting many myokines,especially *** is a polypeptide hormone consisting of 112 amino acids secreted into the blood from muscle and adipose *** irisin levels are associated with cardiometabolic risk factors such as obesity and insulin resistance as defi ned by homeostatic model *** reduces endothelial damage by inhibiting infl ammation and oxidative stress,thus playing a key role in maintaining endothelial cell ***,low irisin levels cause endothelial dysfunction and increase the incidence of *** aimed to summarize the studies on this issue since we have not found any review in the literature on the role of serum irisin levels in the process of atherosclerosis and other cardiovascular events in cardiovascular diseases.

关键词： insulin resistance irisin cardiovascular diseases body mass index

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Association of Serum Chemerin Levels with Coronary Artery Disease: Pathogenesis and Clinical Research

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Cardiovascular Innovations and Applications 2020年第2期4卷 251-256页

作者： Lutfu Askin Hakan Duman Ali Ozyıldız okan tanriverdi Department of Cardiology Adiyaman Education and Research HospitalAdiyamanTurkey Department of Cardiology Faculty of MedicineRecep Tayyip Erdogan UniversityRizeTurkey

Recent studies have revealed that chemerin plays an essential role in the development of cardiovascular *** studies found a strong correlation between the secretion of chemerin in peripheral tissues and aortic and coronary *** chemerin is a marker of systemic infl ammation and is associated with metabolic *** plays a vital role in vascular infl ammation and *** chemerin levels are increased in patients with dilated cardiomyopathy,and chemerin is associated with left ventricular *** this review,we focus on chemerin expression,chemerin processing,its biological function,and its role in the diagnosis of cardiovascular diseases.

关键词： atherosclerosis chemerin heart failure coronary artery disease infl ammation metabolic syndrome

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