检索结果-南通市图书馆

Transanal total mesorectal excision: Myths and reality

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of clinical Oncology 2016年第5期7卷 337-339页

作者： nicolas c buchs Marta Penna Alexander L Bloemendaal Roel Hompes Division of Visceral Surgery Department of Surgery University Hospitals of Geneva Department of colorectal Surgery Churchill Hospital Oxford University Hospitals

Transanal total mesorectal excision(TaTME) is a new and promising approach for the treatment of rectal cancer. Whilst the experience is still limited, there are growing evidences that this approach might overcome the limits of standard low anterior resection. TaTME might help to decrease the conversion rate especially in difficult patients, and to improve the pathological results, while preserving the urogenital function. Evaluation of data from large registries and randomized studies should help to draw firmer conclusions. Beyond these technical considerations, the next challenge seems to be clearly the safe introduction of this approach, motivating the development of dedicated courses.

关键词： Transanal total mesorectal excision Bottom up TAMIS Laparoscopy Robotic Outcomes Rectal cancer

Robotic technology: Optimizing the outcomes in rectal cancer?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of clinical Oncology 2015年第3期6卷 22-24页

作者： nicolas c buchs clinic for Visceral and Transplantation Surgery Department of SurgeryUniversity Hospital of Geneva

Minimally invasive rectal resection remains a challenging procedure, even in experienced hands. Technical limitations explain at least in part the reasons of a relatively poor adoption of laparoscopy for rectal resection, in particular for low tumors in a deep and narrow *** is intended to overcome these *** better short-term outcomes have beenpublished: reduced conversion rates, better functional outcomes, shorter learning curve, reduction of positive margins, better specimen… However, robotic surgery has not yet taken over as the gold standard approach for low anterior resection. Several drawbacks might indeed discourage the most fervent surgeon: the size of the robot, the lack of tactile feedback, the risk and difficulties during multiquadrant surgery, and, of course, costs. Whilst new systems might overcome most of these drawbacks, it seems obvious that the development of robotic surgery is underway. Robotics is not just another interesting technical tool, but more a new concept, which should play a role in the future.

关键词： Robot Laparoscopy Total mesorectal excision Transanal total mesorectal excision Transanal endoscopic microsurgery Outcomes Rectal cancer

Transanal total mesorectal excision:a valid option for rectal cancer?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第41期21卷 11700-11708页

作者： nicolas c buchs Gary A Nicholson Frederic Ris Neil J Mortensen Roel Hompes Department of colorectal Surgery Churchill Hospital Oxford University Hospitals Division of Visceral Surgery Department of Surgery University Hospitals of Geneva Nuffield Department of Surgical Science University of Oxford John Radcliffe Hospital

Low anterior resection can be a challenging operation, especially in obese male patients and in particular after radiotherapy. Transanal total mesorectal excision(Ta TME) might offer technical advantages over laparoscopic or open approaches particularly for tumors in the distal third of the rectum. The aim of this article is to review the current experience with Ta TME. The limits and future developments are also explored. Although the experience with Ta TME is still limited, it might be a promising alternative to laparoscopic TME, especially for difficult cases where laparoscopy is too demanding. The preliminary data on complications and short-term oncological outcomes are good, but also emphasize the importance of careful patient selection. Finally, there is a need for large-scale trials focusing on long-term outcomes and oncological safety before widespread adoption can be recommended.

关键词： Transanal Bottom up Transanal minimally invasive s

Natural history of uncomplicated sigmoid diverticulitis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2015年第11期7卷 313-318页

作者： nicolas c buchs Neil J Mortensen Frederic Ris Philippe Morel Pascal Gervaz Department of colorectal Surgery Oxford University Hospitals Division of Visceral and Transplantation Surgery Department of Surgery Faculty of Medicine University Hospitals of Geneva

While diverticular disease is extremely common, the natural history(NH) of its most frequent presentation(i.e., sigmoid diverticulitis) is poorly investigated. Relevant information is mostly restricted to populationbased or retrospective studies. This comprehensive review aimed to evaluate the NH of simple sigmoid diverticulitis. While there is a clear lack of uniformity in terminology, which results in difficulties interpreting and comparing findings between studies, this review demonstrates the benign nature of simple sigmoid diverticulitis. The overall recurrence rate is relatively low, ranging from 13% to 47%, depending on the definition used by the authors. Among different risk factors for recurrence, patients with c-reactive protein > 240 mg/L are three times more likely to recur. Other risk factors include: Young age, a history of several episodes of acute diverticulitis, medical vs surgical management, male patients, radiological signs of complicated first episode, higher comorbidity index, family history of diverticulitis, and length of involved colon > 5 cm. The risk of developing a complicated second episode(and its corollary to require an emergency operation) is less than 2%-5%. In fact, the old rationale for elective surgery as a preventive treatment, based mainly on concerns that recurrence would result in a progressively increased risk of sepsis or the need for a colostomy, is not upheld by the current evidence.

关键词： Diverticulitis colon cohort Recurrence Natural his

Erratum to:Tribological behaviour of Ti_(3)c_(2)T_(x)nano-sheets:Substrate-dependent tribo-chemical reactions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Friction 2024年第7期12卷 1618-1619页

作者： Alberto ROTA nicolas BELLINA Bo WANG Andreas ROSENKRANZ Dipartimento di Scienze Fisiche Informatiche e MatematicheUniversitàdi Modena e Reggio EmiliaModena 41125Italy cNR-Istituto di Nanoscienze Centro S3Modena 41125Italy centro Interdipartimentale per la Ricerca Applicata e i Servizi nel settore della Meccanica Avanzata e della Motoristica Universitàdi Modena e Reggio EmiliaModena 41125Italy Key Laboratory of Marine New Materials and Related Technology Zhejiang Key Laboratory of Marine Materials and Protection TechnologyNingbo Institute of Material Technology&EngineeringChinese Academy of SciencesNingbo 315201China Department of chemical Engineering Biotechnology and MaterialsUniversity of ChileSantiago 8370456Chile

Erratum to Alberto Rota,nicolas Bellina,Bo Wang&Andreas *** behaviour of Ti_(3)c_(2)T_(x)nano-sheets:Substratedependent tribo-chemical *** 11(8):1522–1533(2023).

关键词： Friction behaviour chemical

On-chip Micro Temperature controllers Based on Freestanding Thermoelectric Nano Films for Low-Power Electronics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2024年第7期16卷 98-108页

作者： Qun Jin Tianxiao Guo nicolas Perez Nianjun Yang Xin Jiang Kornelius Nielsch Heiko Reith Institute for Metallic Materials Leibniz Institute for Solid State and Materials Research01069 DresdenGermany Institute of Materials Engineering University of Siegen57076 SiegenGermany Institute of Applied Physics Technical University of Dresden01069 DresdenGermany Institute of Materials Science Technical University of Dresden01069 DresdenGermany

Multidimensional integration and multifunctional com-ponent assembly have been greatly explored in recent years to extend Moore’s Law of modern ***,this inevitably exac-erbates the inhomogeneity of temperature distribution in microsystems,making precise temperature control for electronic components extremely ***,we report an on-chip micro temperature controller including a pair of thermoelectric legs with a total area of 50×50μm^(2),which are fabricated from dense and flat freestanding Bi2Te3-based ther-moelectric nano films deposited on a newly developed nano graphene oxide membrane *** tunable equivalent thermal resistance is controlled by electrical currents to achieve energy-efficient temperature control for low-power electronics.A large cooling temperature difference of 44.5 K at 380 K is achieved with a power consumption of only 445μW,resulting in an ultrahigh temperature control capability over 100 K mW^(-1).Moreover,an ultra-fast cooling rate exceeding 2000 K s^(-1) and excellent reliability of up to 1 million cycles are *** proposed on-chip temperature controller is expected to enable further miniaturization and multifunctional integration on a single chip for microelectronics.

关键词： Temperature control Low-power electronics On-chip micro temperature controller Freestanding thermoelectric nano films Temperature-sensitive components

A Study of the TPS Based Beam-Matching concept for Medical Linear Accelerators at a Tertiary Hospital

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

International Journal of Medical Physics, clinical Engineering and Radiation Oncology 2024年第1期13卷 16-25页

作者： Ntombela N. Lethukuthula Rovetto J. nicolas Nethwadzi c. Lutendo Mpumelelo Nyathi Department of Radiation Oncology Steve Biko Academic Hospital Pretoria South Africa Department of Medical Physics University of Pretoria Pretoria South Africa Department of Medical Physics Sefako Makgatho Health Sciences University Ga-Rankuwa South Africa

The flexibility in radiotherapy can be improved if patients can be moved between any one of the department’s medical linear accelerators (LINAcs) without the need to change anything in the patient’s treatment plan. For this to be possible, the dosimetric characteristics of the various accelerators must be the same, or nearly the same. The purpose of this work is to describe further and compare measurements and parameters after the initial vendor-recommended beam matching of the five LINAcs. Deviations related to dose calculations and to beam matched accelerators may compromise treatment accuracy. The safest and most practical way to ensure that all accelerators are within clinical acceptable accuracy is to include TPS calculations in the LINAcs matching evaluation. Treatment planning system (TPS) was used to create three photons plans with different field sizes 3 × 3 cm, 10 × 10 cm and 25 × 25 cm at a depth of 4.5 cm in Perspex. calculated TPS plans were sent to Mosaiq to be delivered by five LINAcs. TPS plans were compared with five LINAcs measurements data using Gamma analyses of 2% and 2 mm. The results suggest that for four out of the five LINAcs, there was generally good agreement, less than a 2% deviation between the planned dose distribution and the measured dose distribution. However, one specific LINAc named “Asterix” exhibited a deviation of 2.121% from the planned dose. The results show that all of the LINAcs’ performance were within the acceptable deviation and delivering radiation dose consistently and accurately.

关键词： Radiotherapy Beam-Matching Linear Accelerator Dosimetry

Detailed Analyses of Nymphea Seeds consumed in the Senegal River Valley

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food and Nutrition Sciences 2024年第8期15卷 695-700页

作者： nicolas cyrille Ayessou Michel Bakar Diop Fatou Kiné Gueye césar Bassène Mame Samba Mbaye centre dEtudes sur la Scurit Alimentaire et les Molcules Fonctionnelles (cESAM-REScIF) Universit Cheikh Anta DIOP Dakar Sngal Unit de formation et de Recherche des Sciences Agronomiques de lAquaculture et des Technologies Alimentaires Universit Gaston Berger Saint-Louis Sngal Laboratoire de Botanique-Biodiversit Biologie Vgtale Universit Cheikh Anta Diop Dakar Senegal

Physicochemical investigations were performed on seeds of Nymphea lotus and N. micrantha consumed in the Senegal River valley. They revealed a composition similar to that of cereals. In order to estimate their intrinsic quality, the determination of their amino acid, fatty acid and monosaccharids profiles was done. The results indicate that monosaccharides are represented specifically by saccharose (7%) and glucose (0.67%);a predominance of stearic acid and linoleic acid as unsaturated acids (24.86%);arachidic and palmitic acids as the only saturated acid found (11.12%);a good ratio of unsaturated/saturated acid (2.23);a lack of oleic acid, linoleic, palmitoleic, myristic, caprylic acids;a poor-quality index protein due to low quantity amino acids. Nevertheless, all essential amino acids are present in the seeds. The Nymphea sp grains consumed by the populations around the Senegal River valley offer an interesting nutritional quality linked to fatty acids and carbohydrates.

关键词： Nymphea Seeds composition

Phytochemical Screening and Assays of Phenolic compounds in Senna occidentalis L. Leaf and Seed Extracts

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food and Nutrition Sciences 2024年第7期15卷 499-508页

作者： Edmond Antoine Badock Lahat Niang Abdoulaye Dramé célestine Nkounkou-Loumpangou Omar Touré Omar Sokhna nicolas cyrille Ayessou Mady cissé Ecole Suprieure Polytechnique Laboratoire Eau Energie Environnement et Procds Industriels (LE3PI) Universit Cheikh Anta Diop Dakar Sngal Ecole Suprieure Polytechnique Centre dEtudes sur la Scurit Alimentaire et les Molcules Fonctionnelles (CESAM-RESCIF) Universit Cheikh Anta Diop Dakar Sngal Laboratoire de Valorisation des Produits de la Biomasse Dpartement de Chimie Universit Cheikh Anta Diop de Dakar Dakar Sngal Unit de chimie du Vgtal et de la Vie Facult des Sciences et Techniques Universit Marien NGOUABI Brazzaville Republic of the Congo Laboratoire de chimie Organique et Bio-Organique Dpartement de Chimie Facult des Sciences et Techniques/UCAD Universit Cheikh Anta Diop Dakar Sngal

Phytochemical screening and assay of secondary metabolites, crude extracts with distilled water, aqueous methanol, aqueous acetone and aqueous ethanol of leaves and seeds of Senna occidentalis L. were studied in this work. The aim was to verify the distribution of secondary metabolites according to S. occidentalis organs. Four leaf samples from four different localities (South, East, West and central Senegal) and a mixed sample of seeds were used. Functional molecules such as polyphenols, flavonoids and tannins were then assessed in the leaves and seeds using various standard methods. The results show that Senna occidentalis L. leaf and seed samples display an identical and homogeneous profile, regardless of locality. They contain secondary metabolites and the polyphenol content of extracts from southern, eastern, western and central leaves is: 0.620 - 0.539 - 0.811 - 0.573 g GAE/100 g DM;flavonoids: 0.064 - 0.074 - 0.130 - 0.101 g cE/100 g DM and tannins: 0.326 - 0.264 - 0.269 - 0.494 g TAE/100 g DM. The efficacy of S. occidentalis L. infusions in therapy is thus justified by the presence of these metabolites, whose biological properties are well known. It is then possible to explore isolation of active principles of Senna occidentalis L. leaves and even seeds for producing medicines.

关键词： Senna occidentalis L. Total Polyphenols Flavonoids Tannins