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检索条件"作者=nathan E Lewis"
304 条 记 录,以下是1-10 订阅
排序:
Nat Methods:利用CRISPR-Cas9组合筛选发现癌症弱点
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现代生物医学进展 2017年 第17期17卷 I0001-I0001页
作者: John Paul Shen, Ana Bojorquez-Gomez, Katherine Licon, Kristin Klepper, Daniel Pekin, Alex N Beckett, Kyle Salinas Sanchez, Jason F Kreisberg, Trey Ideker John Paul Shen, Trey Ideker, Prashant Mali John Paul Shen, Dongxin Zhao, Dan Du, Assen Roguev, Jason F Kreisberg, Nevan Krogan, Lei Qi, Trey Ideker, Prashant Mali Dongxin Zhao, Chih-Chung Kuo, Prashant Mali Roman Sasik, Amanda Birmingham, Aaron N Chang, Trey Ideker Jens Luebeck, Alex Thomas Alex Thomas, Chih-Chung Kuo, nathan e lewis Dan Du Assen Roguev, Nevan Krogan nathan e lewis Lei Qi Department of Medicine Division of Genetics University of California San Diego La Jolla California USA Moores UCSD Cancer Center La Jolla California USA The Cancer Cell Map Initiative (CCMI) La Jolla and San Francisco California USA Department of Bioengineering University of California San Diego La Jolla California USA Center for Computational Biology & Bioinformatics University of California San Diego La Jolla California USA Bioinformatics & Systems Biology Program University of California San Diego La Jolla California USA Novo Nordisk Center for Biosustainability at the University of California San Diego La Jolla California USA eli and edythe Broad Center of Regeneration Medicine and Stem Cell Research Department of Cell and Tissue Biology University of California San Francisco San Francisco California USA Department of Cellular and Molecular Pharmacology University of California San Francisco San Francisco California USA Department of Pediatrics University of California San Diego La Jolla California USA Department of Bioengineering Stanford University Stanford California USA.
导致癌症的基因突变也会削弱癌细胞,从而使得人们有机会开发选择性地杀死它们同时不影响正常细胞的药物。这一概念被称作”合成致死性(synthetic lethality)”,这是因为这些药物仅对发生突变的(或者说合成的)细胞是致命性的。在... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Developmental environment contributes to rapid trait shifts among newly colonized subterranean habitats
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Zoological Research 2023年 第4期44卷 808-820页
作者: nathan e.Swanson Andrew G.Gluesenkamp Alexandra e.Donny Suzanne e.McGaugh Department of Fisheries Wildlife and Conservation BiologyUniversity of MinnesotaSaint PaulMN 55108USA Department of ecology and evolutionary Biology University of California IrvineIrvineCA 92697-2525USA Center for Conservation and Research San Antonio ZooSan AntonioTexas 78212USA ecology Evolutionand BehaviorUniversity of MinnesotaSaint PaulMN 55108USA Department of Biology Stanford UniversityStanfordCA 94305USA
Recent colonization of extreme environments provides unique opportunities to study the early steps of adaptation and the potential for rapid convergent ***,phenotypic shifts during recent colonization may also be due ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
nvestigating the role of exiting vehicles and turn indicator usage in gap acceptance at single-lane roundabouts
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Frontiers of Structural and Civil engineering 2017年 第1期11卷 8-16页
作者: nathan P. BeLZ Civil and environmental engineering University of Alaska - Fairbanks Fairbanks AK 99775-5960 USA
Roundabouts are becoming a preferred form of intersection control type due to their safety and capacity benefits. Yield control at roundabout entries inherently reduces fuel consumption and emissions when compared to ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Spectral square moments of a resonance sum for Maass forms
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Frontiers of Mathematics in China 2017年 第5期12卷 1183-1200页
作者: nathan SALAZAR Yangbo Ye Department of Mathematics The University of Iowa Iowa City Iowa 52242-1419 USA
Let f be a Maass cusp form for Г0(N) with Fourier coefficients 1 k2. λf(n) and Laplace eigenvalue 1/4 +k2 For real α≠0 and β 〉 0, consider the sum Sx(f; α,β) = ∑n λf(n)e(αnβ)φ(n/X), where ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
CD44 and CD221 directed magnetic cubosomes for the targeted delivery of helenalin to rhabdomyosarcoma cells
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Nano Research 2023年 第2期16卷 2915-2926页
作者: Hakmin Mun Yuriy Chaban Tanveer A.Tabish Nanasaheb Thorat nathan Cowieson CDavid Owen Helen e.Townley Nuffield Department of Women’s and Reproductive health University of OxfordOxford OX39DUUK electron Bio-Imaging Centre Diamond Light SourceDidcot OX110DEUK Radcliffe Department of Medicine University of OxfordOxford OX37BNUK B21 Diamond Light SourceDidcot OX110DEUK Department of engineering Science University of OxfordOxford OX13PJUK
Confining chemotherapy to tumour sites by means of active targeting nanoparticles(NPs)may increase the treatment effectuality while reducing potential side *** are one of the next-generation drug delivery nanocarriers... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
A comparison of cyanoacrylate to sutures for wound closure following acoustic transmitter insertion in rainbow trout
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Aquaculture and Fisheries 2021年 第5期6卷 513-518页
作者: Jeremy Kientz nathan Huysman Michael e.Barnes South Dakota Department of Game Fish and Parks4130 Adventure TrailRapid CitySD57702USA South Dakota Department of Game Fish and ParksMcNenny State Fish Hatchery19619 Trout LoopSpearfishSD57783USA
Tag retention,wound healing,wound closure,and tagged fish survival are critically important after surgical implantation of acoustic transmitters in *** study compared the use of sutures to cyanoacrylate adhesives and ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Town-scale microbial sewer community and H2S emissions response to common chemical and biological dosing treatments
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Journal of environmental Sciences 2020年 第1期32卷 133-148页
作者: elizabeth R.Mathews Jennifer L.Wood Dean Phillips nathan Billington Dean Barnett Ashley e.Franks Department of Physiology Anatomy and MicrobiologyLa Trobe UniversityMelbourneAustralia Centre for Future Landscapes La Trobe UniversityMelbourneAustralia Faculty of Science Engineering and TechnologySwinburne University of TechnologyMelbourneAustralia Western Water SunburyAustralia
Controlling hydrogen sulfide(H2S)odors and emissions using a single,effective treatment across a town-scale sewer network is a challenge faced by many water *** of a sewer diversion provided the opportunity to compare... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
MIXeD INTeRIOR PeNALTY DISCONTINUOUS GALeRKIN MeTHODS FOR ONe-DIMeNSIONAL FULLY NONLINeAR SeCOND ORDeR eLLIPTIC AND PARABOLIC eQUATIONS
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Journal of Computational Mathematics 2014年 第2期32卷 107-135页
作者: Xiaobing Feng Thomas lewis Department of Mathematics The University of Tennessee Knoxville TN 37996 U.S.A. Department of Mathematics and Statistics The University of North Carolina at Greensboro NC 27402 U.S.A.
This paper is concerned with developing accurate and efficient numerical methods for one-dimensional fully nonlinear second order elliptic and parabolic partial differential equations (PDes). In the paper we present... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Nigral dopaminergic neuron replenishment in adult mice through Ve-cadherin-expressing neural progenitor cells
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Neural Regeneration Research 2017年 第11期12卷 1865-1869页
作者: Abir A.Rahman nathan K.Lai Joshua e.Albright Paige e.Urquhart Abby R.Webb Brad e.Morrison Department of Biological Sciences Boise State UniversityBoiseIDUSA Biomolecular Ph.D.Program Boise State UniversityBoiseIDUSA Department of Biological Sciences Boise State UniversityBoiseIDUSA
The function of dopaminergic neurons in the substantia nigra is of central importance to the coordination of movement by the brain's basal ganglia circuitry. This is evidenced by the loss of these neurons, resulting ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
environmental cues determine the fate of astrocytes after spinal cord injury
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Neural Regeneration Research 2017年 第12期12卷 1964-1970页
作者: Fatima M.nathan Shuxin Li Shriners Hospitals Pediatric Research Center Department of Anatomy and Cell Biology Lewis Katz School of Medicine at Temple UniversityPhiladelphia PA USA
Reactive astrogliosis occurs after central nervous system(CNS) injuries whereby resident astrocytes form rapid responses along a graded continuum. Following CNS lesions, na?ve astrocytes are converted into reactive... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论