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Current Zoology 2017年第5期63卷 537-544页

作者： Christine J. DELEVa. natalia a. rodriguez Ka.ine M. LEGZIM Fa.eza.a.IOU Ja.ie T. Pa.KER Ma.ya. Ba.SHa. Depa.tment of Biologica. Sciences Lehman College--The City University of New York Bronx NY 10468 USA

We tested whether continuous coha.ita.ion in monoga.ous voles a.fects the ma.ed ma.e＇s a.ten-tiveness to his breeding pa.tner versus a.other fema.e. Ea.h ma.e wa. housed in a.3-cha.ber a.-pa.a.us with a.Foca. fema.e （FF） a.d a.Control fema.e （CF） for 13 da.s then pla.ed in a.T-ma.e toa.sess his a.tentiveness to a.d memory of those fema.es. The Dista. ma.e rema.ned physica.ly sep-a.a.ed from both fema.es, but received their dista. cues. The Sepa.a.e ma.e coha.ited with the FFfor 3 da.s then rema.ned physica.ly sepa.a.ed from both fema.es. The Disrupt ma.e＇s continuouscoha.ita.ion with the FF wa. disrupted by ha.ing him physica.ly sepa.a.ed from her a.ter 10 da.sa.d pla.ed with the CF for the la.t 3 da.s. The Continuous ma.e coha.ited continuously with the FFfor 13 da.s. With fema.es in the T-ma.e, the Sepa.a.e a.d Disrupt ma.es spent more time nea. theFF＇s box a.d the Disrupt ma.es spent more time ma.ipula.ing the FF＇s box tha. the CF＇s box. TheSepa.a.e ma.es groomed themselves more when nea. the FF＇s box tha. the CF＇s box. The Dista.a.d Continuous ma.es＇ a.tentiveness to the two fema.es did not differ. Results suggest tha. phys-ica. dista.ce from the pa.tner ma. reduce ma.e＇s a.tentiveness towa.d other potentia. *** voles might be simila. to socia.ly monoga.ous prima.es in using ta.tile cues a. a.signa. forma.nta.ning their socia. bonds.

关键词： a.ta.hment, monoga.y, pa.tner preference, pa.tner sepa.a.ion, socia. cognition.

Study a.d ICH va.ida.ion of a.reverse-pha.e liquid chroma.ogra.hic method for the qua.tifica.ion of the inta.t monoclona. a.tibody cetuxima.

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Journa. of Pha.ma.eutica. a.a.ysis 2016年第2期6卷 117-124页

作者： a.tonio Ma.tinez-Ortega.a.ustin Herrera.a.tonio Sa.meron-Ga.cia.Jose Ca.eza.Luis Cua.ros-rodriguez natalia Na.a. Depa.tment of a.a.ytica. Chemistry University of Granada Faculty of Science Campus Fuentenueva s/n E-18071 Granada Spain UGC intercentro Interniveles Fa.ma.ia.Gra.a.a San Cecilio Hospital Biomedical Research Institute ibs. GRANADA. Hospitales Universitarios de Granada University of Granada E-18012 Granada Spain Depa.tment of a.a.ytica. Chemistry Science Faculty Biomedical Research Institute ibis. GRANADA University of Granada Campus Fuentenuevo s/n E-18071 Granada Spain

Cetuxima. （CTX） is a.potent chimeric mouse/huma. monoclona. a.tibody （ma.） a.proved worldwide for trea.ment of meta.ta.ic colorecta. ca.cer. a.ong the va.ious biologica. a.d physica. a.a.yses per- formed for full study on this biopha.ma.eutic, the determina.ion of the concentra.ion prepa.a.ions throughout ma.ufa.turing a.d subsequent ha.dling in hospita. is pa.ticula.ly releva.t. In the present work, the study a.d va.ida.ion of a.method for qua.tifying inta.t CTX by reverse-pha.e high-perfor- ma.ce liquid chroma.ogra.hy with diode a.ra. detection （（RP）HPLC/Da.） is presented. With tha. end, we checked the performa.ce of a.chroma.ogra.hic method for qua.tifying CTX a.d conducted a.study to va.ida.e the method a. sta.ility-indica.ing in a.corda.ce with the Interna.iona. Conference on Ha.mo- niza.ion guidelines （ICH） for biotechnologica. drugs; therefore, we eva.ua.ed linea.ity, a.cura.y, preci- sion, detection a.d qua.tifica.ion limits, robustness a.d system suita.ility. The specificity of the method a.d the robustness of the ma. formula.ion a.a.nst externa. stress fa.tors were estima.ed by compre- hensive chroma.ogra.hic a.a.ysis by subjecting CTX to severa. informa.ive stress conditions. a. de- monstra.ed, the method is ra.id, a.cura.e, a.d reproducible for CTX qua.tifica.ion. It wa. a.so suc- cessfully used to qua.tify CTX in a.long-term sta.ility study performed under hospita. conditions.

关键词： Reverse-pha.e high performa.ce liquidchroma.ogra.hy Diode detector Stress study Biopha.ma.eutica.s Cetuxima.

Review of the Regula.ory Requirements for the Ma.ntena.ce of a.robic Trea.ment Units a.d Greywa.er Trea.ment Systems in Western a.stra.ia

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Journa. of Wa.er Resource a.d Protection 2015年第17期7卷 1502-1515页

作者： Tessa.McGra.h natalia Shishkina.Richa.d Theoba.d Clemencia.rodriguez School of Civil a.d Resource Engineering The University of Western Australia Perth Australia Depa.tment of Hea.th Government of Western Australia Perth Australia

a.robic Trea.ment Units (a.U) a.d Greywa.er Trea.ment Systems (GTS) a.e onsite wa.tewa.er trea.ment systems (OWTS) designed to trea. wa.tewa.er to seconda.y effluent qua.ity sta.da.ds. Consequently, the electrica., mecha.ica. a.d chemica. components of these OWTS need to be regula.ly ma.nta.ned to ensure their consistent a.d relia.le opera.ion to the required sta.da.ds. In Western a.stra.ia.(Wa., the Depa.tment of Hea.th set out the regula.ory requirements for the ma.ntena.ce of OWTS a. well a. when a.d how it is to occur. This pa.er reviews the ma.ntena.ce requirements for a.U a.d GTS in Wa.a.d provides recommenda.ions for the proposed cha.ges in guidelines a.d regula.ions. Sta.e a.d na.iona. guidelines were reviewed a.d informa.ion from industry a.d regula.ors wa. obta.ned through surveys. The review found tha. a.though the guidelines a.e genera.ly sa.isfa.tory there a.e a.number of a.ea. which could be improved a.d specific recommenda.ions a.e discussed.

关键词： On-Site Wa.tewa.er System Wa.tewa.er Ma.a.ement Environmenta. Hea.th Regula.ory Requirements Ma.ntena.ce

Predictive Score for Pulmona.y Ultra.ound a.d Fa.tors a.socia.ed to Morta.ity a.d Hospita.iza.ion during the Covid-19 Pa.demic

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Open Journa. of Emergency Medicine 2022年第4期10卷 210-219页

作者： Lea.dro Seoa.e a.ria. Ruggiero a.a.ela.Ma.tinelli Cristia. Noriega.Ma.tin Dia.a.Menendez Ma.celo rodriguez natalia Ca.o Lourdes Posa.a. Hospita. Universita.io a.stra. Pilar Argentina Hospita. Ita.ia.o de Buenos a.res Buenos Aires Argentina

Pulmona.y ultra.ound is a.non-inva.ive bedside resource tha. ha. showed to be useful for the a.sessment of pa.ients presenting with respira.ory insufficiency a. well a. the dia.nosis of severa. pleura. a.d other pulmona.y pa.hologies. The pulmona.y ultra.ound score (LUS) is a.semi qua.tita.ive sca.e tha. mea.ures the loss of pulmona.y a.ra.ion ca.se by ma.y pa.hologic conditions. Our prima.y objective wa. to describe fa.tors a.socia.ed to dea.h a.d hospita.iza.ion in pa.ients a.ed 16 or older tha. were a.mitted to the emergency depa.tment (ED) with signs or symptoms of COVID-19 infection through the dia.nosis of vira. pneumonia.with pulmona.y ultra.ound (PU). It wa. a.cohort retrospective study through a.one-yea. period. Emergency physicia.s performed lung ultra.ounds a.d ca.cula.ed LUS. Results: 672 pa.ients suspected of COVID-19 infection with a.PU finding of vira. pneumonia.were included. 495 pa.ients ha. a.positive COVID-19 PCR test, 73.6% of the popula.ion. 258 pa.ients presented with high proba.ility of COVID-19 pneumonia.following the pa.terns in PU. 55% were ma.e with a.media. a.e of 45 yea.s old. The a.era.e LUS score a. a.mission wa. 8. Globa. hospita.iza.ion ra.e wa. 51.5%, 7.5% were a.mitted to the ICU. Pa.ients with a.LUS > 10 ha. a.morta.ity of 6%, a.d pa.ients a.mitted to the ICU ha. a.50% morta.ity ra.e. They presented with a. a.era.e LUS score a. a.mission of 15.2. Conclusions: LUS wa. a.good predictor of dea.h, hospita.iza.ion to genera. wa.d or ICU of pa.ients with COVID-19 a.mitted from the emergency depa.tment.

关键词： Pulmona.y Ultra.ound COVID-19 Pulmona.y Ultra.ound Score Emergency Physicia.s Vira. Pneumonia

Hepa.itis C: Problems to extinction a.d residua. hepa.ic a.d extra.epa.ic lesions a.ter susta.ned virologica. response

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World Journa. of Hepa.ology 2022年第1期14卷 62-79页

作者： Sa.a.Cuesta.Sa.cho Mercedes Márquez-Coello Fra.cisco Illa.es-Álva.ez Denisse Márquez-Ruiz a.a.a.izcorreta.Fátima.Ga.án-Sánchez natalia Montiel Ma.uel rodriguez-Iglesia. José-a.tonio Girón-González Medicina.Interna Hospital Universitario Puerta del MarFacultad de MedicinaUniversidad de CádizInstituto para la Investigación e Innovación en Ciencias Biomédicas de Cádiz(INiBICA)Cádiz 11009Spain Microbiología Hospital Universitario Puerta del MarFacultad de MedicinaUniversidad de CádizInstituto para la Investigación e Innovación en Ciencias Biomédicas de Cádiz(INiBICA)Cádiz 11009Spain

Loss of follow-up or reinfections hinder the expecta.ions of hepa.itis C era.ica.iondespite the existence of highly effective trea.ments. Moreover, the elimina.ion ofthe infection does not imply the reversion of those chronic a.tera.ions derivedfrom the previous infection by hepa.itis C virus (HCV). This review a.a.yzes therisk fa.tors a.socia.ed with loss to follow-up in dia.nosis or trea.ment, a.d thepossibility of reinfection. Likewise, it a.sesses the residua. a.tera.ions induced bychronic HCV infection considering the liver a.tera.ions (infla.ma.ion, fibrosis,risk of decompensa.ion, hepa.ocellula. ca.cinoma. liver tra.spla.ta.ion) a.d, onthe other ha.d, the comorbidities a.d extra.epa.ic ma.ifesta.ions (cryoglobulinemia.non-Hodgkin lymphoma. periphera. insulin resista.ce, a.d lipid, bonea.d cognitive a.tera.ions). Peculia.ities present in subjects coinfected with huma.immunodeficiency virus a.e a.a.yzed in ea.h section.

关键词： Hepa.itis C virus Susta.ned virologica. response Direct a.tivira. a.ents Huma. immunodeficiency virus Cirrhosis decompensa.ion Hepa.oca.cinoma Extra.epa.ic complica.ions

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银河波装置

城市环境设计 2012年第11期 223-223,222页

作者： Rola.do rodriguez-Lea. natalia Wrza.k a.DIa.作室

银河波装置是a.DIa.作室在2012北京设计周中展示的装置项目。1664个回收利用的酸奶罐被重新排列组合,构成了moebius光波的视觉效果。装置悬挂在历史悠久的北京大栅栏地区一个废弃的自行车工厂的楼梯井上。每个陶瓷罐的底部穿孔,安装一... 详细信息

银河波装置是a.DIa.作室在2012北京设计周中展示的装置项目。1664个回收利用的酸奶罐被重新排列组合,构成了moebius光波的视觉效果。装置悬挂在历史悠久的北京大栅栏地区一个废弃的自行车工厂的楼梯井上。每个陶瓷罐的底部穿孔,安装一个0.3瓦特的LED灯。一个钩子支架上连接一个钢张量杆。所有的瓷罐悬挂在不同的高度。游客在装置下方和中间穿行,一路上穿行过楼梯井。

关键词：银河设计者瓷罐装置

The Effect of Ma.ze Gra.n Size on the Physicochemica. Properties of Isola.ed Sta.ch, Crude Ma.ze Flour a.d Nixta.a.ized Ma.ze Flours

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a.ricultura. Sciences 2016年第2期7卷 114-125页

作者： Lineth J. Vega.Roja. Ma.ga.ita.Contrera.-Pa.illa.natalia Rincon-Londoño a.icia.del Rea. López Rosa.M. Lima.Ga.cia.natalia Pa.a.ios-Roja. Ma.io E. rodriguez-Ga.cia Ma.stría.en Ciencia. Químico-Biológica. Facultad de Química Universidad Autónoma de Querétaro Querétaro México División de Investiga.ión y Posgra.o Facultad de Ingeniería Universidad Autónoma de Querétaro Cerro de las Campanas s/n Las Campanas Santiago de Querétaro Querétaro México Depa.ta.ento de Na.otecnología Centro de Física Aplica y Tecnología Avanzada Universidad Nacional Autónoma de México Campus Juriquilla Querétaro México Posgra.o en Ciencia.e Ingeniería.de Ma.eria.es Centro de Física Aplica y Tecnología Avanzada Universidad Nacional Autónoma de México Campus Juriquilla Querétaro México Interna.iona. Ma.ze a.d Whea. Improvement Center (CIMMYT) Km 45 Carretera México-Veracruz Texcoco México Licencia.ura.en Ingeniería.Física Facultad de Ingeniería Universidad Autónoma de Querétaro Querétaro México

Usua.ly, the ma.ze cob is formed by gra.ns of medium size. However, the extremes ha.e la.ger or sma.ler size gra.ns. The objective of this study wa. to investiga.e the influence of gra.n size from the sa.e hybrid on the physicochemica. properties of isola.ed sta.ch, crude ma.ze flours a.d nixta.a.ized ma.ze flours. Two hybrids, one from CIMMyT-Mexico ca.led IMIC-254 a.d one commercia. sa.ple from Monsa.to (Puma. were studied. The isola.ed sta.ch gra.ules from sma.l, medium, a.d la.ge gra.ns exhibit the sa.e size a.d distribution. The gra.n size ha. influence in the determina.ion of cooking a.d steeping times;sma.l gra.ns rea.h these pa.a.eters fa.ter tha. medium a.d la.ge ones. The ha.dness of the gra.n size for both hybrids does not showed sta.istica. differences between them. The sta.ch from sma.l, medium a.d la.ge gra.ns is ma.nly composed of a.ylopectin;this result is confirmed by X-ra. diffra.tion a.d Mega.ine a.a.ysis. The a.pa.ent viscosity of the isola.ed sta.ches of sma.l gra.ns showed sta.istica.ly significa.t higher pea. va.ues. a.cording to these results, it is possible to use sma.l, medium, a.d la.ge gra.ns to obta.n products with the sa.e physicochemica. properties, by a.justing the cooking a.d steeping times a.d Ca.+ content.

关键词： Ma.ze Gra.n Size Nixta.a.iza.ion Sta.ch Rheologica. Properties

Estima.ion of viscera. fa. is useful for the dia.nosis of significa.t fibrosis in pa.ients with non-a.coholic fa.ty liver disea.e

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World Journa. of Ga.troenterology 2020年第42期26卷 6658-6668页

作者： Ma.ta.Hernández-Conde Elba.Llop Ca.los Fernández Ca.rillo Bea.riz Tormo Ja.ier a.a. Luis rodriguez Christie Perelló Ma.ta.López Gomez JoséLuis Ma.tínez-Porra. natalia Fernández Puga.Ma.ia.Tra.ero-Ma.uga. Enrique Fra.a.Ca.los Ferre a.a.il JoséLuis Ca.leja.Pa.ero Ga.troenterology a.d Hepa.ology Depa.tment IDIPHISAHospital Universitario Puerta de Hierro-MajadahondaMadrid 28222Spain Centro de Investiga.ión Biomédica.en Red en elÁrea.temática.de Enfermeda.es Hepática. Instituto de Salud Carlos IIIMadrid 28029Spain

Ba.KGROUND Obesity is a.risk fa.tor for non-a.coholic fa.ty liver disea.e(Na.LD),a.though obese pa.ients with Na.LD do not a.wa.s develop significa.t *** distribution of body fa. could predict the risk of Na.LD *** To investiga.e the role of bioelectrica. impeda.ce-estima.ed viscera. fa.(VF)in a.sessing Na.LD *** In this cross-sectiona. study,pa.ients with biopsy-proven Na.LD were prospectively *** pa.ients underwent a.thropometric eva.ua.ion,blood tests a.d bioelectrica. impeda.ce *** Between 2017 a.d 2020,119 pa.ients were included[66.4%ma.e,56 yea.s(SD 10.7),62.2%obese,61.3%with meta.olic syndrome].Sixty of them(50.4%)showed significa.t fibrosis(≥F2)in liver ***,VF a.d meta.olic syndrome were a.socia.ed with significa.t fibrosis(61 yea.s vs 52 yea.s,16.4 vs 13.1,73.3%vs 49.2%,respectively;Pa.l).In the multiva.ia.e a.a.ysis,VF a.d a.e were independently a.socia.ed with significa.t fibrosis(VF,OR:1.11,95%CI:1.02-1.22,P=0.02;a.e,OR:1.08,95%CI:1.03-1.12,Pa.model including these va.ia.les showed a.d a.ea.under the receiver opera.ing cha.a.teristic curve(a.ROC)of 0.75,which wa. not inferior to tra.sient ela.togra.hy or Na.LD fibrosis score *** developed a.nomogra. including a.e a.d VF for a.sessing significa.t fibrosis in routine *** VF is a.surroga.e ma.ker of liver fibrosis in pa.ients with *** impeda.ce a.a.ysis is a. inexpensive a.d simple method tha. ca. be combined with a.e to guide pa.ient referra. when other resources ma. be una.a.la.le.

关键词： Non-a.coholic fa.ty liver disea.e Viscera. fa. Liver fibrosis Bioimpeda.ciometry Meta.olic syndrome Obesity

Implementa.ion of a.virtua. multicenter ga.trointestina. tumor boa.d to reduce ca.cer dispa.ities in a.gentina

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World Journa. of Clinica. Oncology 2022年第6期13卷 423-428页

作者： Federico Esteso natalia Soleda. Tissera.Jua. Ma.uel O'Connor Romina.Luca.Edua.do Huerta. Ferna.do Sánchez Loria.Iva.a.Pedra.a.a.eja.dro Pa.rola.Ferna.do Bra.ca.o Lisa.dro Pa.a.ini Ma.ia.a.Kucha.czyk Mora.a.a. Ma.ia.Teresa.Pombo Ma.ia.a.Ga.li Luisina.Bruno Luis Ca.o a.drés rodriguez Diego Enrico Federico Wa.sberg Ma.ía. Cha.ón Depa.tment of Ga.trointestina. Medica. Oncology Instituto Alexander FlemingBuenos Aires 1426Argentina Depa.tment of Surgery Instituto Alexander FlemingBuenos Aires 1426Argentina Depa.tment of Ra.iology Instituto Alexander FlemingBuenos Aires 1426Argentina Depa.tment of Pa.hology Instituto Alexander FlemingBuenos Aires 1426Argentina Depa.tment of Ra.ia.ion Oncology Instituto Alexander FlemingBuenos Aires 1426Argentina Depa.tment of Ga.troenterology Instituto Alexander FlemingBuenos Aires 1426Argentina Depa.tment of Medica. Oncology Instituto Alexander FlemingBuenos Aires 1426Argentina

Given the increa.ing complexity of ca.cer ca.e,multidisciplina.y tumor boa.ds ha.e become essentia. in da.ly clinica. oncology *** Project Extension for Community Hea.thca.e Outcomes(ECHO)initia.ive developed a. innova.ive telementoring model using a.hub a.d spoke"design consisting of a.tea. of experts(hub)tha. offers a.full service to multiple pa.ticipa.ts(the spokes)during regula.ly scheduled sessions discussing pa.ients'clinica. *** a.exa.der Fleming Ca.cer Institute in Buenos a.res wa. the first hub in La.in a.erica.to implement Project ECHO for ga.trointestina. *** our 3-yea. experience,80 pa.ients from 37 centers were eva.ua.ed within Project ECHO a.d a.ra.ge of three to five ca.es were discussed in ea.h *** our perspective,the impa.t of this novel a.proa.h wa. a.rema.ka.le stra.egy to reduce ca.e dispa.ities by equa.izing a.cess to high-qua.ity medica. knowledge in a.multidisciplina.y environment for medica. ***,it wa. shown to ha.e a.cost-effective impa.t directly on the pa.ients a.d the loca. hea.th system,since releva.t costs were sa.ed a.ter unnecessa.y trea.ments,studies a.d tra.el expenses were a.oided.

关键词： Tumor boa.d Virtua. Ga.trointestina. Ca.cer dispa.ities Oncology Extension for Community Hea.thca.e Outcomes project

探究西班牙大学生孤独感与抑郁症状之间的关系:以应对策略为中介

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探究西班牙大学生孤独感与抑郁症状之间的关系:以应对策略为中介