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Spontaneous intracranial hypotension complicated with cerebral venous thrombosis and subdural effusion:a case report

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Neuroimmunology and Neuroinflammation 2016年第1期3卷 104-108页

作者： murali krishna menon Thara Prathap Muhammed Jasim Abdul Jalal Department of Neurology Lakeshore Hospital and Research CentreErnakulam 682040KeralaIndia Department of Radiology Lakeshore Hospital and Research CentreErnakulam 682040KeralaIndia Department of Family Medicine Lakeshore Hospital and Research CentreErnakulam 682040KeralaIndia

Spontaneous intracranial hypotension treatment can be complicated by concomitant cerebral venous thrombosis and subdural hematoma.A 48 years old male,presenting orthostatic headache and neck pain for 1 month displayed sagittal sinus thrombosis and bilateral subdural effusions,as well as extradural fluid collection at T3-T8 level,upon magnetic resonance *** fluid opening pressure was 50 mmH2O,and a leak was confirmed at C2-C3 level by computed tomography(CT)*** presence of subdural hematoma precluded anticoagulation *** autologous epidural blood patch at C2-C3 level under CT guidance improved the patient’s condition,remaining free of residual symptoms or recurrence at six-month follow-up.

关键词： Spontaneous intracranial hypotension cerebral venous thrombosis subdural effusion autologous epidural blood patch

Artery of Percheron occlusion:role of diffusion-weighted imaging in the early diagnosis

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Neuroimmunology and Neuroinflammation 2016年第1期3卷 14-16页

作者： murali krishna menon Suma Mariam Jacob Muhammed Jasim Abdul Jalal Department of Neurology Lakeshore Hospital and Research CentreErnakulam 682040KeralaIndia Department of Radiology Lakeshore Hospital and Research CentreErnakulam 682040KeralaIndia Department of Family Medicine Lakeshore Hospital and Research CentreErnakulam 682040KeralaIndia

Bilateral thalamic infarcts have a low frequency among different subtypes of *** it does not involve a particular vascular territory,it therefore usually involves the occlusion of the artery of Percheron(AOP).Here we report a 79-year-old right-handed Parkinsonian female patient,who was found unresponsive in *** examination,the patient was drowsy with a Glasgow Coma Score(GCS)of 10/15(E2M5V3).She had absent doll’s eye response with anisocoric pupils and intermittent vertical gaze *** the patient had no apparent motor deficits,she was in a state of persistent somnolence with memory impairment and lack of ***-weighted magnetic resonance imaging(MRI)of the brain showed focal areas of restricted diffusion in the medial part of the thalami bilaterally and the rostral part of mid-brain(right>left)(bilateral paramedian thalamic with mid-brain pattern),suggestive of a hyper-acute infarct in the territory of *** patient was anticoagulated with 40 mg subcutaneous low molecular weight heparin and was started on double anti-platelets along with supportive *** level of consciousness is improved at a slow rate to a GCS of 12/15(E4M5V3).The patient had marked abulia with periods of drowsiness interspersed with periods of restlessness and uttering of abnormal sounds,but she was able to execute simple *** conclusion,occlusion of the AOP is a rare cause of coma in elderly ***-weighted MRI is the imaging modality of choice for early *** diagnosis of AOP occlusion may lead to favorable outcomes.

关键词： Artery of Percheron bilateral thalamic infarcts coma diffusion-weighted imaging thalamic dementia

IoT Task Offloading in Edge Computing Using Non-Cooperative Game Theory for Healthcare Systems

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1487-1503页

作者： Dinesh Mavaluru Chettupally Anil Carie Ahmed I.Alutaibi Satish Anamalamudi Bayapa Reddy Narapureddy murali krishna Enduri Md Ezaz Ahmed School of Computing and Informatics Saudi Electronic UniversityRiyadhSaudi Arabia Department of Computer Engineering SRM University APGunturIndia College of Computer and Information Sciences Majmaah UniversityAl Majma’ahSaudi Arabia Department of Public Health College of Applied Medical SciencesKing Khalid UniversityAbhaSaudi Arabia

In this paper,we present a comprehensive system model for Industrial Internet of Things(IIoT)networks empowered by Non-Orthogonal Multiple Access(NOMA)and Mobile Edge Computing(MEC)*** network comprises essential components such as base stations,edge servers,and numerous IIoT devices characterized by limited energy and computing *** central challenge addressed is the optimization of resource allocation and task distribution while adhering to stringent queueing delay constraints and minimizing overall energy *** system operates in discrete time slots and employs a quasi-static approach,with a specific focus on the complexities of task partitioning and the management of constrained resources within the IIoT *** study makes valuable contributions to the field by enhancing the understanding of resourceefficient management and task allocation,particularly relevant in real-time industrial *** results indicate that our proposed algorithmsignificantly outperforms existing approaches,reducing queue backlog by 45.32% and 17.25% compared to SMRA and ACRA while achieving a 27.31% and 74.12% improvement in Qn ***,the algorithmeffectively balances complexity and network performance,as demonstratedwhen reducing the number of devices in each group(Ng)from 200 to 50,resulting in a 97.21% reduction in complexity with only a 7.35% increase in energy *** research offers a practical solution for optimizing IIoT networks in real-time industrial settings.

关键词： Internet of Things edge computing offloading NOMA

Role of long non-coding RNAs in non-alcoholic fatty liver disease

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World Journal of Meta-Analysis 2024年第3期12卷 1-5页

作者： Anju Mullath murali krishna Department of Gastroenterology Aster Royal HospitalMuscat 133MuscatOman Department of Urology Army HospitalR&RDelhi Cantonment 110010DelhiIndia

Non-alcoholic fatty liver disease(NAFLD)is emerging as a common cause of chronic liver disease in children and *** can progress to steatohepa-titis and potentially even hepatocellular *** identification of pati-ents at risk for progressive disease is crucial for managing *** studies have identified long noncoding RNAs(lncRNAs),circular RNAs,and microRNAs as playing important roles in the pathogenesis of *** noncoding RNAs are involved in modulating several metabolic pathways such as hepatic glucose and lipid metabolism,oxidative stress,and even *** levels of lncARSR and lncRNA nuclear-enriched abundant transcript 1 have been found in patients with *** addition,lncRNAs such as PRYP4-3 and RP11-128N14.5 can distinguish patients with NAFLD from healthy *** MEG3 expression has been observed in both NAFLD and non-alcoholic steatohepatitis,suggesting that it may help predict patients at risk for disease *** advances in transcriptomics,we may discover additional targets to help in the identification and prognostication of NAFLD.

关键词： Long noncoding RNA Non-alcoholic fatty liver disease Plasmacytoma variant translocation 1 Nuclear-enriched abundant transcript 1 Muscle-and adiposeassociated long intergenic non-coding RNA H19

Hepatocellular carcinoma-time to take the ticket

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World Journal of Gastrointestinal Surgery 2019年第6期11卷 287-295页

作者： Anju Mullath murali krishna Department of Gastroenterology Lakeshore Hospital and Research CentreKochi 682040KeralaIndia Department of Surgery Military HospitalPalampur 176061Himachal PradeshIndia

Hepatocellular carcinoma is one of the leading malignancies *** detection of hepatocellular carcinoma and its management in the form of liver transplantation offers an attractive treatment *** Milan criteria,proposed by Mazzaferro et al,have been the standard for selecting patients with hepatocellular carcinoma for ***,several studies have shown that even patients selected outside the Milan criteria can undergo transplantation with a relatively good *** article examines the currently existing criteria other than the Milan criteria and also evaluates use of alpha-fetoprotein and positron emission tomography scans to predict the chance of recurrence.

关键词： Hepatocellular carcinoma Milan Alpha-fetoprotein Positron emission tomography

Dynamic properties and liquefaction behaviour of cohesive soil in northeast India under staged cyclic loading

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Journal of Rock Mechanics and Geotechnical Engineering 2018年第5期10卷 958-967页

作者： Shiv Shankar Kumar A.murali krishna Arindam Dey Department of Civil Engineering Indian Institute of Technology Guwahati

Estimation of strain-dependent dynamic soil properties, e.g. the shear modulus and damping ratio, along with the liquefaction potential parameters, is extremely important for the assessment and analysis of almost all geotechnical problems involving dynamic loading. This paper presents the dynamic properties and liquefaction behaviour of cohesive soil subjected to staged cyclic loading, which may be caused by main shocks of earthquakes preceded or followed by minor foreshocks or aftershocks, respectively. Cyclic triaxial tests were conducted on the specimens prepared at different dry densities （1.5 g/cm3 and 1.75 g/cm3） and different water contents ranging from 8% to 25%. The results indicated that the shear modulus reduction （G/Gmax） and damping ratio of the specimen remain unaffected due to the changes in the initial dry density and water content. Damping ratio is significantly affected by confining pressure, whereas G/Gmax is affected marginally. It was seen that the liquefaction criterion of cohesive soils based on single-amplitude shear strain （3.75% or the strain at which excess pore water pressure ratio becomes equal to 1, whichever is lower） depends on the initial state of soils and applied stresses. The dynamic model of the regional soil, obtained as an outcome of the cyclic triaxial tests, can be successfully used for ground response analysis of the region.

关键词： Cohesive soil Dynamic soil properties Liquefaction potential Cyclic triaxial tests Staged cyclic loading

New variation of median arcuate ligament compression causing hepatic arterial hypoperfusion during liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2020年第4期19卷 394-395页

作者： Noel Cassar Stephen Gregory krishna menon Institute of Liver Studies King’s Healthcare PartnersDenmark Hill SiteLondon SE59RSUK

Satisfactory blood flow after hepatic arterial anastomosis in liver transplantation is a critical point of the *** with this anastomosis can result in hepatic artery thrombosis with resultant graft failure and patient morbidity and *** of hepatic artery thrombosis include problematic technique,hepatic artery dissection,external compression(*** hematoma),hypercoagulable state,splenic arterial steal and rarer causes such as median arcuate ligament compression(MALC).A careful review of preoperative radiology and imaging will reveal these rare instances and enable a proper intraoperative plan.

关键词： hepatic arterial ligament

The Rationale for Reviewing Current Concepts of Urban Planning and Developing New Ones in India

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Built Heritage 2017年第3期1卷 34-43页

作者： A.G.krishna menon Departments of Architecture and Urban Design School of Planning and ArchitectureNew DelhiIndia

Urban planning in India is heir to a colonial paradigm that imposed practices developed from the experiences of Western urbanisation to the local Indian *** paper suggests that this paradigm exacerbates the complex problems of contemporary urbanisation,but there is little attempt among Indian urban planners to acknowledge and address the consequences of their colonial *** forces of globalisation are reinforcing this postcolonial intellectual malaise by reposing greater faith in capital-and technology-intensive solutions to solve problems instead of reforming the inherited processes of urban *** paper argues that the nascent field of urban conservation in India offers the potential to review the dominant paradigms of urban planning and develop more context-specific and appropriate strategies for tackling the problems of Indian urbanisation.

关键词： historic space historic metropolitan context evolution reflection

Redundant Transmission Control Algorithm for Information-Centric Vehicular IoT Networks

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Computers, Materials & Continua 2023年第8期76卷 2217-2234页

作者： Abdur Rashid Sangi Satish Anamalamudi Mohammed SAlkatheiri murali krishna Enduri Anil Carie Mohammed AAlqarni Department of Computer Science College of Science and TechnologyWenzhou-Kean UniversityWenzhou325060China Department of Computer Science Engineering SRM University APAmaravati522502India Department of Cybersecurity College of Computer Science&EngineeringUniversity of JeddahJeddahSaudi Arabia Department of Software Engineering College of Computer Science&EngineeringUniversity of JeddahJeddahSaudi Arabia

Vehicular Adhoc Networks(VANETs)enable vehicles to act as mobile nodes that can fetch,share,and disseminate information about vehicle safety,emergency events,warning messages,and passenger ***,the continuous dissemination of information fromvehicles and their one-hop neighbor nodes,Road Side Units(RSUs),and VANET infrastructures can lead to performance degradation of VANETs in the existing hostcentric IP-based ***,Information Centric Networks(ICN)are being explored as an alternative architecture for vehicular communication to achieve robust content distribution in highly mobile,dynamic,and errorprone *** ICN-based Vehicular-IoT networks,consumer mobility is implicitly supported,but producer mobility may result in redundant data transmission and caching inefficiency at intermediate vehicular *** paper proposes an efficient redundant transmission control algorithm based on network coding to reduce data redundancy and accelerate the efficiency of information *** proposed protocol,called Network Cording Multiple Solutions Scheduling(NCMSS),is receiver-driven collaborative scheduling between requesters and information sources that uses a global parameter expectation deadline to effectively manage the transmission of encoded data packets and control the selection of information *** results for the proposed NCMSS protocol is demonstrated to analyze the performance of ICN-vehicular-IoT networks in terms of caching,data retrieval delay,and end-to-end application *** end-to-end throughput in proposed NCMSS is 22%higher(for 1024 byte data)than existing solutions whereas delay in NCMSS is reduced by 5%in comparison with existing solutions.

关键词： Caching data dissemination redundancy control ICN-vehicular IoT networks