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A novel medical image data protection scheme for smart healthcare system

CAAI Transactions on Intelligence Technology 2024年第4期9卷 821-836页

作者： Mujeeb Ur Rehman Arslan Shafique muhammad shahbaz Khan Maha Driss Wadii Boulila Yazeed Yasin Ghadi Suresh Babu Changalasetty Majed Alhaisoni Jawad Ahmad School of Computer Science and Informatics Cyber Technology InstituteDe Montfort UniversityLeicesterUK Department of Biomedical Engineering University of GlasgowGlasgowUK School of Computing Engineering and the Built EnvironmentEdinburgh Napier UniversityEdinburghUK Robotics and Internet‐of‐Things Laboratory Prince Sultan UniversityRiyadhSaudi Arabia Department of Computer Science Al Ain UniversityAl AinUnited Arab Emirates Department of Computer Engineering College of Computer Science King Khalid UniversityAbhaSaudi Arabia Computer Sciences Department College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityRiyadhSaudi Arabia

The Internet of Multimedia Things(IoMT)refers to a network of interconnected multimedia devices that communicate with each other over the ***,smart healthcare has emerged as a significant application of the IoMT,particularly in the context of knowledge‐based learning *** healthcare systems leverage knowledge‐based learning to become more context‐aware,adaptable,and auditable while maintain-ing the ability to learn from historical *** smart healthcare systems,devices capture images,such as X‐rays,Magnetic Resonance *** security and integrity of these images are crucial for the databases used in knowledge‐based learning systems to foster structured decision‐making and enhance the learning abilities of ***,in knowledge‐driven systems,the storage and transmission of HD medical images exert a burden on the limited bandwidth of the communication channel,leading to data trans-mission *** address the security and latency concerns,this paper presents a lightweight medical image encryption scheme utilising bit‐plane decomposition and chaos *** results of the experiment yield entropy,energy,and correlation values of 7.999,0.0156,and 0.0001,*** validates the effectiveness of the encryption system proposed in this paper,which offers high‐quality encryption,a large key space,key sensitivity,and resistance to statistical attacks.

关键词： data analysis medical image processing security

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青蒿琥酯联合用药及作用机制研究进展

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中国实验方剂学杂志 2024年第3期30卷 290-298页

作者：张雨婷 muhammad shahbaz 张蕊王变利张会敏山东中医药大学药学院济南250355 山东省中医药研究院国家中医药管理局济南250014 山东大学附属齐鲁医院济南250012 山东大学基础医学院济南250100 山东省东营同安胸外科医院东营257300

青蒿素是一种从菊科蒿属植物黄花蒿(Artemisia annua)中分离出来的倍半萜类天然产物,青蒿琥酯(artesunate)是其衍生物之一,具有经济、速效、低毒、不易产生耐受等特点。目前临床主要用于脑型疟疾及各种重症疟疾的抢救,对疟原虫红内期有... 详细信息

青蒿素是一种从菊科蒿属植物黄花蒿(Artemisia annua)中分离出来的倍半萜类天然产物,青蒿琥酯(artesunate)是其衍生物之一,具有经济、速效、低毒、不易产生耐受等特点。目前临床主要用于脑型疟疾及各种重症疟疾的抢救,对疟原虫红内期有强大且快速杀灭的作用,能够迅速控制临床发作及症状。除此之外,青蒿琥酯还具有抗肿瘤、抗病毒、抗肝纤维化、抗炎、抗菌、保护肝细胞、免疫调节等药理作用,抑制细胞增殖、诱导细胞凋亡及下调血症水平。以青蒿素类化合物为基础的联合疗法(ACTs)是多国治疗疟疾的一线方法,主要包括蒿甲醚-本芴醇、青蒿琥酯-阿莫地喹和青蒿甲醚-苯甲酰胺等。近年来国内外学者对青蒿琥酯进行了研究,发现相对于单一疗法而言,青蒿琥酯联合疗法在增强药理作用、缩短用药时长和减少不良反应等方面更具有优越性。该文通过Web of Science核心合集(Web of Science Core Collection)系统检索并通过CiteSpace(6.2.1)软件对其进行整合,综述了近5年来青蒿琥酯联合其他药物在抗疟、抗肿瘤、抗菌和抗病毒等方面的作用机制并对其进行阐述,旨在为进一步合理开发利用青蒿琥酯及新药研发提供一定的理论依据。

关键词：青蒿琥酯联合疗法作用机制抗疟抗肿瘤

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The Influence of Depression on Different Age and Gender Groups in Bahawalpur

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Journal of Clinical and Nursing Research 2024年第7期8卷 196-207页

作者： Mehran Khan muhammad shahbaz Tooba Waris Shoaib Yaseen Iqra Afzal Emaan Khadim Sawera Usman muhammad Ismail Shah Sulaiman Aslam Zafar Iqbal Bahawalpur College of Pharmacy BMDC Complex63100PunjabPakistan

In Bahawalpur,a cross-sectional study assessed depression prevalence across age and gender groups,involving 442 participants from diverse socioeconomic backgrounds and *** the PHQ9 questionnaire,84%were found to meet depression *** findings revealed a higher incidence in females(88%)than males(79%),with the greatest disparity among young adults,particularly young women,due to factors like academic pressure and financial *** children had the lowest depression rates(68%),possibly due to better *** individuals exhibited more severe depression,likely related to aging and domestic *** study’s findings highlight a significant variation in depression severity across different demographic groups,with an overall higher incidence in *** research underscores the necessity for targeted mental health resources and interventions tailored to the specific needs of each demographic *** also points to the importance of addressing academic and socioeconomic stressors to mitigate depression,particularly among young *** the study provides valuable insights,it relies on self-reported data,which may introduce ***,future research should include clinical assessments to validate these findings and ensure a more accurate representation of depression within the community.

关键词： Influence Depression Different age Gender groups Bahawalpur

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Efficient Process Monitoring Under General Weibull Distribution

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Computer Systems Science & Engineering 2022年第1期40卷 287-297页

作者： Saman Hanif shahbaz muhammad Qaiser shahbaz Department of Statistics King Abdulaziz UniversityJeddahKingdom of Saudi Arabia

Product testing is a key ingredient in maintaining the quality of a pro-duction *** production process is considered an efficient process if it is capable of quick identification of faulty *** items produced by any production process are usually packed and acceptance or rejection of the pack depends upon its conformity to some specified quality ***,the specified quality level is based upon the number of defective items found in the inspected number of *** decisions are based upon some rules and usually acceptance of the pack is based upon a fewer number of defective items in the *** questions can be answered by using acceptance sampling *** acceptance sampling plans assume the fact that the quality level of the item follows some probability *** sampling plans based upon some classical probability distributions are available but often it happens that the quality behavior of the product does not follow a simple probability model and hence the available sampling plans *** this paper,we have developed acceptance sampling plans when the product life follows a general Weibull *** sampling plans have been constructed by considering the crisp and fuzzy behavior of the acceptance *** sampling plans have been constructed by assuming an infinite lot *** has been found that the number of items required for inspection decreases with an increase in some parameters.

关键词： General Weibull distribution sampling plans acceptance probability fuzzy plan

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On Relations for Moments of Generalized Order Statistics for Lindley–Weibull Distribution

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Computer Systems Science & Engineering 2022年第4期41卷 197-208页

作者： Faten A.Momen khan Saman Hanif shahbaz muhammad Qaiser shahbaz Department of Statistics University of JeddahJeddahKingdom of Saudi Arabia Department of Statistics King Abdulaziz UniversityJeddahKingdom of Saudi Arabia

Moments of generalized order statistics appear in several areas of science and *** moments are useful in studying properties of the random variables which are arranged in increasing order of importance,for example,time to failure of a computer *** computation of these moments is sometimes very tedious and hence some algorithms are *** algorithm is to use a recursive method of computation of these moments and is very useful as it provides the basis to compute higher moments of generalized order statistics from the corresponding lower-order *** order statistics pro-vides several models of ordered data as a special *** moments of general-ized order statistics also provide moments of order statistics and record values as a special *** this research,the recurrence relations for single,product,inverse and ratio moments of generalized order statistics will be obtained for Lindley–Weibull *** relations will be helpful for obtained moments of gen-eralized order statistics from Lindley–Weibull distribution *** cases of the recurrence relations will also be *** characterizations of the distribution will also be obtained by using moments of generalized order *** relations for moments and characterizations can be used in differ-ent areas of computer sciences where data is arranged in increasing order.

关键词： Generalized order statistics Lindley–Weibull distribution recurrence relations moments

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A New S-Box Design System for Data Encryption Using Artificial Bee Colony Algorithm

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Computers, Materials & Continua 2023年第10期77卷 781-797页

作者： Yazeed Yasin Ghadi Mohammed SAlshehri Sultan Almakdi Oumaima Saidani Nazik Alturki Fawad Masood muhammad shahbaz Khan Department of Computer Science Al Ain UniversityAbu Dhabi112612United Arab Emirates Department of Computer Science College of Computer Science and Information SystemsNajran UniversityNajran61441Saudi Arabia Department of Information Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Electrical Engineering Institute of Space TechnologyIslamabad4400Pakistan School of Computing Engineering and the Built EnvironmentEdinburgh Napier UniversityEdinburghEH105DTUK

Securing digital image data is a key concern in today’s information-driven *** encryption techniques are required to protect sensitive image data,with the Substitution-box(S-box)often playing a pivotal role in many symmetric encryption *** study introduces an innovative approach to creating S-boxes for encryption *** proposed S-boxes are tested for validity and non-linearity by incorporating them into an image encryption *** nonlinearity measure of the proposed S-boxes is *** qualities significantly enhance its resistance to common cryptographic attacks,ensuring high image data ***,to assess the robustness of the S-boxes,an encryption system has also been proposed and the proposed S-boxes have been integrated into the designed encryption *** validate the effectiveness of the proposed encryption system,a comprehensive security analysis including brute force attack and histogram analysis has been *** addition,to determine the level of security during the transmission and storage of digital content,the encryption system’s Number of Pixel Change Rate(NPCR),and Unified Averaged Changed Intensity(UACI)are *** results indicate a 99.71%NPCR and 33.51%*** results demonstrate that the proposed S-boxes offer a significant level of security for digital content throughout its transmission and storage.

关键词： S-box chaos artificial bee colony image encryption

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Prediction of the SARS-CoV-2 Derived T-Cell Epitopes’Response Against COVID Variants

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Computers, Materials & Continua 2023年第5期75卷 3517-3535页

作者： Hassam Tahir muhammad shahbaz Khan Fawad Ahmed Abdullah M.Albarrak Sultan Noman Qasem Jawad Ahmad Department of Electrical Engineering HITEC UniversityTaxila47080Pakistan Department of Cyber Security Pakistan Navy Engineering CollegeNUSTKarachi75350Pakistan Computer Science Department College of Computer and Information SciencesImam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11432Saudi Arabia School of Computing Edinburgh Napier UniversityEdinburghEH105DTU.K

TheCOVID-19 outbreak began in December 2019 andwas declared a global health emergency by the World Health *** four most dominating variants are Beta,Gamma,Delta,and *** the administration of vaccine doses,an eminent decline in new cases has been *** COVID-19 vaccine induces neutralizing antibodies and T-cells in our ***,strong variants likeDelta and Omicron tend to escape these neutralizing antibodies elicited by COVID-19 ***,it is indispensable to study,analyze and most importantly,predict the response of SARS-CoV-2-derived t-cell epitopes against Covid variants in vaccinated and unvaccinated *** this regard,machine learning can be effectively utilized for predicting the response of COVID-derived t-cell *** this study,prediction of T-cells Epitopes’response was conducted for vaccinated and unvaccinated people for Beta,Gamma,Delta,and Omicron *** dataset was divided into two classes,i.e.,vaccinated and unvaccinated,and the predicted response of T-cell Epitopes was divided into three categories,i.e.,Strong,Impaired,and *** the aforementioned prediction purposes,a self-proposed Bayesian neural network has been designed by combining variational inference and flow normalization ***,the Hidden Markov Model has also been trained on the same dataset to compare the results of the self-proposed Bayesian neural network with this state-of-the-art statistical *** experimentation and results demonstrate the efficacy of the proposed network in terms of accurate prediction and reduced error.

关键词： Omicron COVID-19 hidden Markov model Bayesian neural network

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Bivariate Beta–Inverse Weibull Distribution:Theory and Applications

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Computer Systems Science & Engineering 2021年第1期36卷 83-100页

作者： Ali Algarni muhammad Qaiser shahbaz Department of Statistics Faculty of ScienceKing Abdulaziz UniversityJeddahSaudi Arabia

Probability distributions have been in use for modeling of random phenomenon in various areas of *** of probability distributions has been the area of interest of several authors in the recent *** situations arise where joint modeling of two random phenomenon is *** such cases the bivariate distributions are *** of the bivariate distributions necessitates certain conditions,in a field where few work has been *** paper deals with a bivariate beta-inverse Weibull *** marginal and conditional distributions from the proposed distribution have been *** for the joint and conditional density functions for the proposed distribution have been *** properties,including product,marginal and conditional moments,joint moment generating function and joint hazard rate function of the proposed bivariate distribution have been *** study for the dependence function has been implemented to see the effect of various parameters on the dependence of *** of the parameters of the proposed bivariate distribution has been done by using the maximum likelihood method of *** and real data application of the distribution are presented.

关键词： Bivariate beta distribution inverse Weibull distribution conditional moments maximum likelihood estimation

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Mobilization and Acquisition of Sparingly Soluble P-Sources by Brassica Cultivars under P-Starved Environment I. Differential Growth Response,P-Efficiency Characteristics and P-Remobilization

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Journal of Integrative Plant Biology 2009年第11期51卷 1008-1023页

作者： muhammad shahbaz Akhtar Yoko Oki Tadashi Adachi Department of Environmental Management Engineering Faculty of Environmental Science and TechnologyThe Graduate School of Environmental ScienceOkayama University

Phosphorus （P） starvation is highly notorious for limiting plant growth around the globe. To combat P-starvation, plants constantly sense the changes in their environment, and elicit an elegant myriad of plastic responses and rescue strategies to enhance P-solublization and acquisition from bound soil P-forms. Relative growth responses, P-solublization and P- acquisition ability of 14 diverse Brassica cultivars grown with sparingly soluble P-sources （Rock-P （RP） and Ca3（PO4）2 （TCP）） were evaluated in a solution culture experiment. Cultivars showed considerable genetic diversity in terms of biomass accumulation, concentration and contents of P and Ca in shoots and roots, P-stress factor （PSF） and P use efficiency. Cultivars showed variable P-stress tolerance, and cultivars depicting low PSF and high P-efficiency values were better adaptable to P-starvation. In experiment 2, after initial feeding on optimum nutrition for 12 d after transplanting （DAT）, class-I （low P-tolerant （Oscar and Con-II）） and class-II （low P-sensitive （Gold Rush and RL-18）） cultivars were exposed to P-free environment for 25 d. All of the cultivars remobilized P from above ground parts to their roots during growth in P-free environment, the magnitude of which was variable in tested cultivars. P-concentrations （[P]s） at 37 DAT were higher in developing compared with developed leaves. Translocation of absorbed P from metabolically inactive to active sites in P- stressed plants may have helped class-I cultivars to establish a better rooting system, which provided a basis for enhanced P-utilization efficiency （PUE） and tolerance against P-stress. By supplying TCP and RP spatially separated from other nutrients in split root study, class-I cultivars were still able to mobilize RP and TCP more efficiently compared with class-II cultivars. To compare the growth behavior under P-stress, cultivars were grown in pots for 41 d after sowing, using a soil low in P （NaHCO3-extractable P = 3.97 mg/kg, Mehlich

关键词： Brassica Ca3(PO4)2 P-remobilization P-stress P-use efficiency P-stress factor rock phosphate.

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Microplastics affect activity and spatial distribution of C,N, and P hydrolases in rice rhizosphere

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Soil Ecology Letters 2023年第3期5卷 13-24页

作者： Yaoyao Tong Jina Ding Mouliang Xiao muhammad shahbaz Zhenke Zhu Ming Chen Yakov Kuzyakov Yangwu Deng Jianping Chen Tida Ge School of Resources and Environmental Engineering Jiangxi University of Science and TechnologyGanzhou 341000China State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products Institute of Plant VirologyNingbo UniversityNingbo 315211China Centre for Environmental and Climate Science Lund University22362 LundSweden Department of Soil Science of Temperate Ecosystems Department of Agricultural Soil ScienceUniversity of Göttingen37077 GöttingenGermany

Microplastics provide a new ecological niche for microorganisms,and the accumulation levels of microplastics(MPs)in terrestrial ecosystems are higher than those in marine ***,we applied the zymography to investigate how MPs–polyethylene[PE],and polyvinyl chloride[PVC])at two levels(0.01%and 1%soil weight)impacted the spatial distribution of soil hydrolases,nutrient availability,and rice growth in paddy *** increased the above-ground biomass by 13.0%–15.5%and decreased the below-ground biomass by 8.0%–15.1%.Addition of 0.01%and 1%MPs reduced soil NH4+content by 18.3%–63.2%and 52.2%–80.2%,*** average activities of N-and P-hydrolases increased by 0.8%–4.8%and 1.9%–6.3%with addition of MPs,*** nutrient uptake by rice plants and the enzyme activities in hotspots increased with MP content in *** accumulation of MPs in paddy soil could provide an ecological niche that facilitates microbial survival,alters the spatial distribution of soil hydrolases,and decreases nutrient availability.

关键词： MPs accumulation Soil zymography Microbial hotspots Soil nutrients Soil hydrolases

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