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International Journal of Biomathematics 2024年第4期17卷 1-38页

作者： muhammad aqib Abbasi Department of Mathematics Quaid-I-Azam University Islamabad44230Pakistan

The study of the population dynamics of a three-species Lotka-Volterra model is crucial in gaining a deeper understanding of the delicate balance between prey and predator *** research takes a unique approach by exploring the stability of fixed points and the occurrence of Hopf *** using the bifurcation theory,our study provides a comprehensive analysis of the conditions for the existence of Hopf *** is validated through detailed numerical simulations and visual representations that demonstrate the potential for chaos in these *** mitigate this instability,we employ a hybrid control strategy that ensures the stability of the controlled model even in the presence of Hopf *** research is not only significant in advancing the field of ecology but also has far-reaching practical implications for wildlife management and conservation *** results provide a deeper understanding of the complex dynamics of prey-predator interactions and have the potential to inform sustainable management practices and ensure the survival of these species.

关键词： Fixed points existence and uniqueness Hopf bifurcation

Under the influence of crowding effects:Stability,bifurcation and chaos control for a discrete-time predator-prey model

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International Journal of Biomathematics 2019年第4期12卷 185-213页

作者： muhammad aqib Abbasi Qamar Din Department of Mathematics University of the Poonch Rawalakot Pakistan

The interaction between predators and preys exhibits more complicated behavior under the influence of crowding effects. By taking into account the crowding effects, the qualitative behavior of a prey-predator model is investigated. Particularly, we examine the boundedness as well as existence and uniqueness of positive steady-state and stability analysis of the unique positive steady-state. Moreover, it is also proved that the system undergoes Hopf bifurcation and flip bifurcation with the help of bifurcation theory. Moreover, a chaos control technique is proposed for controlling chaos under the influence of bifurcations. Finally, numerical simulations are provided to illustrate the theoretical results. These results of numerical simulations demonstrate chaotic long-term behavior over a broad range of parameters. The presence of chaotic behavior in the model is confirmed by computing maximum Lyapunov exponents.

关键词： Prey-predator model stability analysis boundedness flip bifurcation Hopfbifurcation chaos control

Mining Software Repository for Cleaning Bugs Using Data Mining Technique

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Computers, Materials & Continua 2021年第10期69卷 873-893页

作者： Nasir Mahmood Yaser Hafeez Khalid Iqbal Shariq Hussain muhammad aqib muhammad Jamal Oh-Young Song University Institute of Information Technology Pir Mehr Ali Shah Arid Agriculture UniversityRawalpindi46000Pakistan Department of Computer Science COMSATS University IslamabadAttock CampusAttock43600Pakistan Department of Software Engineering Foundation University IslamabadIslamabad44000Pakistan Department of Mathematics and Statistics Pir Mehr Ali Shah Arid Agriculture UniversityRawalpindi46000Pakistan Department of Software Sejong UniversitySeoul05006Korea

Despite advances in technological complexity and efforts,software repository maintenance requires reusing the data to reduce the effort and ***,increasing ambiguity,irrelevance,and bugs while extracting similar data during software development generate a large amount of data from those data that reside in ***,there is a need for a repository mining technique for relevant and bug-free data *** paper proposes a fault prediction approach using a data-mining technique to find good predictors for high-quality *** predict errors in mining data,the Apriori algorithm was used to discover association rules by fixing confidence at more than 40%and support at least 30%.The pruning strategy was adopted based on evaluation ***,the rules were extracted from three projects of different domains;the extracted rules were then combined to obtain the most popular rules based on the evaluation measure *** evaluate the proposed approach,we conducted an experimental study to compare the proposed rules with existing ones using four different industrial *** evaluation showed that the results of our proposal are *** and developers can utilize these rules for defect prediction during early software development.

关键词： Fault prediction association rule data mining frequent pattern mining

Metal-Doped Brushite Cement for Bone Regeneration

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Journal of Bionic Engineering 2023年第6期20卷 2716-2731页

作者： muhammad aqib Aneela Anwar Humayun Ajaz Samina Akbar Ahsan Manzoor Maham Abid Zohaib Waheed Qudsia Kanwal Department of Chemistry University of Engineering and TechnologyGT RoadLahore54890Pakistan Department of Chemistry University of LahoreLahore5400Pakistan

For the past several years,calcium phosphate cement was used in the biomedical *** biocompatibility,good bioactivity,self-setting qualities,minimum setting degree,appropriate toughness,and simple shape to accommodate any difficult geometry are among their most notable *** phosphate has some types and brushite is one of the most attractive mineral for bone repair *** is extensively employed in filling fractures and trauma treatments as a bone substituted *** kind of material can potentially be used as a medicine delivery *** replacement of metal,such as magnesium,zinc,and strontium ions,into the calcium phosphate structure is a major research topic these *** cement has low mechanical strength and quick setting *** is possible to produce biomaterials with higher mechanical *** adding metal that are great potential in controlling cellular density when included into *** a result,it is a successful method to develop quite well regenerative *** paper provides a detailed summary of the present achievements of metal-doped brushite cement for bone repair and healing *** major purpose of this work is to give a simple but thorough analysis of current successes in brushite cement doped with Zn,Mg,Sr,and other ions as well as to highlight new advancements and *** impact of metal replacement on cement physical and chemical properties,including microstructure,setting time,injectability,mechanical property,and ion release,is *** metal-doped cement has osteogenesis,angiogenesis,and antibacterial properties,as well as their prospective utility as drug carriers,also considered.

关键词： Calcium phosphate Brushite Bone cement Metal dopants Bone regeneration

Towards Improving the Quality of Requirement and Testing Process in Agile Software Development:An Empirical Study

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Computers, Materials & Continua 2024年第9期80卷 3761-3784页

作者： Irum Ilays Yaser Hafeez Nabil Almashfi Sadia Ali Mamoona Humayun muhammad aqib Ghadah Alwakid University Institute of Information Technology Pir Mehr Ali Shah Arid Agriculture UniversityRawalpindi46000Pakistan Department of Software Engineering College of Computer and Information SciencesJouf UniversityAl Jouf72388Saudi Arabia School of Arts Humanities and Social Sciences University of RoehamptonLondonSW155PJUK Department of Computer Science College of Computer and Information SciencesJouf UniversityAl Jouf72388Saudi Arabia

Software testing is a critical phase due to misconceptions about ambiguities in the requirements during specification,which affect the testing ***,it is difficult to identify all faults in *** requirement changes continuously,it increases the irrelevancy and redundancy during *** to these challenges;fault detection capability decreases and there arises a need to improve the testing process,which is based on changes in requirements *** this research,we have developed a model to resolve testing challenges through requirement prioritization and prediction in an agile-based *** research objective is to identify the most relevant and meaningful requirements through semantic analysis for correct change *** compute the similarity of requirements through case-based reasoning,which predicted the requirements for reuse and restricted to error-based ***,the apriori algorithm mapped out requirement frequency to select relevant test cases based on frequently reused or not reused test cases to increase the fault detection ***,the proposed model was evaluated by conducting *** results showed that requirement redundancy and irrelevancy improved due to semantic analysis,which correctly predicted the requirements,increasing the fault detection rate and resulting in high user *** predicted requirements are mapped into test cases,increasing the fault detection rate after changes to achieve higher user ***,the model improves the redundancy and irrelevancy of requirements by more than 90%compared to other clustering methods and the analytical hierarchical process,achieving an 80%fault detection rate at an earlier ***,it provides guidelines for practitioners and researchers in the modern *** the future,we will provide the working prototype of this model for proof of concept.

关键词： Requirement prediction software testing agile software development semantic analysis case-based reasoning

Engineered Nano−Bio Interfaces for Stem Cell Therapy

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Precision Chemistry 2023年第6期1卷 341-356页

作者： Arsalan Umer muhammad Daniyal Ghouri Theoneste Muyizere Raja muhammad aqib Abdul Muhaymin Rong Cai Chunying Chen CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety&CAS Center for Excellence in Nanoscience and Technology of China Chinese Academy of Sciences(CAS)Beijing 100190China University of Chinese Academy of Sciences Beijing 100049China GBA National Institute for Nanotechnology Innovation Guangdong 5110700China

Engineered nanomaterials(ENMs)with different topographies provide effective nano−bio interfaces for controlling the differentiation of stem *** interaction of stem cells with nanoscale topographies and chemical cues in their microenvironment at the nano−bio interface can guide their *** use of nanotopographical cues,in particular nanorods,nanopillars,nanogrooves,nanofibers,and nanopits,as well as biochemical forces mediated factors,including growth factors,cytokines,and extracellular matrix proteins,can significantly impact stem cell *** factors were seen as very effective in determining the proliferation and spreading of stem *** specific outgrowth of stem cells can be decided with size variation of topographic nanomaterial along with variation in matrix stiffness and surface structure like a special *** precision chemistry enabled controlled design,synthesis,and chemical composition of ENMs can regulate stem cell *** parameters of size such as aspect ratio,diameter,and pore size of nanotopographic structures are the main factors for specific termination of stem *** corona nanoparticles(NPs)have shown a powerful facet in stem cell therapy,where combining specific proteins could facilitate a certain stem cell differentiation and cellular ***−bio reactions implicate the interaction between biological entities and nanoparticles,which can be used to tailor the stem cells’*** ion release can also be a parameter to enhance cellular proliferation and to commit the early differentiation of stem *** research is needed to fully understand the mechanisms underlying the interactions between engineered nano−bio interfaces and stem cells and to develop optimized regenerative medicine and tissue engineering designs.

关键词： nano−bio interface protein corona stem cell therapy extracellular matrix biochemical forces

Regression analysis of squeezing-induced hybrid nanofluid flow in Darcy-Forchheimer porous medium

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 193-208页

作者： K.muhammad M.SARFRAZ Department of Humanities and Sciences School of Electrical Engineering and Computer Science National University of Sciences and Technology Department of Mathematics Quaid-i-Azam University

This article presents a mathematical model addressing a scenario involving a hybrid nanofluid flow between two infinite parallel plates. One plate remains stationary, while the other moves downward at a squeezing velocity. The space between these plates contains a Darcy-Forchheimer porous medium. A mixture of water-based fluid with gold(Au) and silicon dioxide(Si O2) nanoparticles is formulated. In contrast to the conventional Fourier's heat flux equation, this study employs the Cattaneo-Christov heat flux equation. A uniform magnetic field is applied perpendicular to the flow direction, invoking magnetohydrodynamic(MHD) effects. Further, the model accounts for Joule heating, which is the heat generated when an electric current passes through the fluid. The problem is solved via NDSolve in MATHEMATICA. Numerical and statistical analyses are conducted to provide insights into the behavior of the nanomaterials between the parallel plates with respect to the flow, energy transport, and skin *** findings of this study have potential applications in enhancing cooling systems and optimizing thermal management strategies. It is observed that the squeezing motion generates additional pressure gradients within the fluid, which enhances the flow rate but reduces the frictional drag. Consequently, the fluid is pushed more vigorously between the plates, increasing the flow velocity. As the fluid experiences higher flow rates due to the increased squeezing effect, it spends less time in the region between the plates. The thermal relaxation, however, abruptly changes the temperature, leading to a decrease in the temperature fluctuations.

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Single-cell and spatial omics:exploring hypothalamic heterogeneity

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Neural Regeneration Research 2025年第6期20卷 1525-1540页

作者： muhammad Junaid Eun Jeong Lee Su Bin Lim Department of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Graduate School of Ajou UniversitySuwonSouth Korea Department of Brain Science Ajou University School of MedicineSuwonSouth Korea

Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technologies have significantly evolved, overcoming initial technical challenges in capturing and analyzing individual cells. These high-throughput omics technologies now offer a remarkable opportunity to comprehend the complex spatiotemporal patterns of transcriptional diversity and cell-type characteristics across the entire hypothalamus. Current single-cell and single-nucleus RNA sequencing methods comprehensively quantify gene expression by exploring distinct phenotypes across various subregions of the hypothalamus. However, single-cell/single-nucleus RNA sequencing requires isolating the cell/nuclei from the tissue, potentially resulting in the loss of spatial information concerning neuronal networks. Spatial transcriptomics methods, by bypassing the cell dissociation, can elucidate the intricate spatial organization of neural networks through their imaging and sequencing technologies. In this review, we highlight the applicative value of single-cell and spatial transcriptomics in exploring the complex molecular-genetic diversity of hypothalamic cell types, driven by recent high-throughput achievements.

关键词： cellular diversity hypothalamus multi-omics single-cell transcriptomics spatial transcriptomics

Solid Waste Management:A MADM Approach Using Fuzzy Parameterized Possibility Single-Valued Neutrosophic Hypersoft Expert Settings

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 531-553页

作者： Tmader Alballa muhammad Ihsan Atiqe Ur Rahman Noorah Ayed Alsorayea Hamiden Abd El-Wahed Khalifa Department of Mathematics College of SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia 2 Department of Mathematics University of Management and TechnologyLahore54000Pakistan Department of Mathematics College of ScienceQassim UniversityBuraydah51452Saudi Arabia

The dramatic rise in the number of people living in cities has made many environmental and social problems *** search for a productive method for disposing of solid waste is the most notable of these *** scholars have referred to it as a fuzzy multi-attribute or multi-criteria decision-making problem using various fuzzy set-like approaches because of the inclusion of criteria and anticipated *** goal of the current study is to use an innovative methodology to address the expected uncertainties in the problem of solid waste site *** characteristics(or sub-attributes)that decision-makers select and the degree of approximation they accept for various options can both be indicators of these *** tackle these problems,a novel mathematical structure known as the fuzzy parameterized possibility single valued neutrosophic hypersoft expert set(ρˆ-set),which is initially described,is integrated with a modified version of Sanchez’s *** this,an intelligent algorithm is *** steps of the suggested algorithm are explained with an example that explains *** compatibility of solid waste management sites and systems is discussed,and rankings are established along with detailed justifications for their *** study’s strengths lie in its application of fuzzy parameterization and possibility grading to effectively handle the uncertainties embodied in the parameters’nature and alternative approximations,*** uses specific mathematical formulations to compute the fuzzy parameterized degrees and possibility grades that are missing from the prior *** is simpler for the decisionmakers to look at each option separately because the decision is *** the computed results,it is discovered that they are consistent and dependable because of their preferred properties.

关键词： Hypersoft expert set Sanchez’s method decision making optimization solid waste management possibility grade fuzzy parameterization

Alternative Strategy for Development of Dielectric Calcium Copper Titanate‑Based Electrolytes for Low‑Temperature Solid Oxide Fuel Cells

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Nano-Micro Letters 2025年第1期17卷 310-332页

作者： Sajid Rauf muhammad Bilal Hanif Zuhra Tayyab Matej Veis MAKYousaf Shah Naveed Mushtaq Dmitry Medvedev Yibin Tian Chen Xia Martin Motola Bin Zhu College of Mechatronics and Control Engineering Shenzhen UniversityShenzhen 518060People’s Republic of China Department of Inorganic Chemistry Faculty of Natural SciencesComenius University BratislavaIlkovicova684215 BratislavaSlovakia Energy Storage Joint Research Center School of Energy and EnvironmentSoutheast UniversityNanjing 210096People’s Republic of China Hydrogen Energy Laboratory Ural Federal University620002 EkaterinburgRussia Laboratory of Electrochemical Devices Based on Solid Oxide Proton Electrolytes Institute of High Temperature Electrochemistry620066 EkaterinburgRussia School of Microelectronics Hubei UniversityWuhan 430062People’s Republic of China

The development of low-temperature solid oxide fuel cells(LT-SOFCs)is of significant importance for realizing the widespread application of *** has stimulated a substantial materials research effort in developing high oxide-ion conductivity in the electrolyte layer of *** this context,for the first time,a dielectric material,CaCu_(3)Ti_(4)O_(12)(CCTO)is designed for LT-SOFCs electrolyte application in this *** individual CCTO and its heterostructure materials with a p-type Ni_(0.8)Co_(0.15)Al_(0.05)LiO_(2−δ)(NCAL)semiconductor are evaluated as alternative electrolytes in LT-SOFC at 450–550℃.The single cell with the individual CCTO electrolyte exhibits a power output of approximately 263 mW cm^(-2) and an open-circuit voltage(OCV)of 0.95 V at 550℃,while the cell with the CCTO–NCAL heterostructure electrolyte capably delivers an improved power output of approximately 605 mW cm^(-2) along with a higher OCV over 1.0 V,which indicates the introduction of high hole-conducting NCAL into the CCTO could enhance the cell performance rather than inducing any potential short-circuiting *** is found that these promising outcomes are due to the interplay of the dielectric material,its structure,and overall properties that led to improve electrochemical mechanism in CCTO–***,density functional theory calculations provide the detailed information about the electronic and structural properties of the CCTO and NCAL and their heterostructure CCTO–*** study thus provides a new approach for developing new advanced electrolytes for LT-SOFCs.

关键词： LT-SOFCs Dielectric CaCu_(3)Ti_(4)O_(12) Semiconductor Ni_(0.8)Co_(0.15)Al_(0.05)LiO_(2−δ) Ionic conductivity Heterostructure electrolyte