检索结果-南通市图书馆

Fluoride passivation of ZnO electron transport layers for efcient PbSe colloidal quantum dot photovoltaics

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Optoelectronics 2023年第3期16卷 141-151页

作者： Jungang He You Ge Ya Wang mohan yuan Hang Xia Xingchen Zhang Xiao Chen Xia Wang Xianchang Zhou Kanghua Li Chao Chen Jiang Tang Hubei Key Laboratory of Plasma Chemistry and Advanced Materials Hubei Engineering Technology Research Center of Optoelectronic and New Energy MaterialsSchool of Materials Science and EngineeringWuhan Institute of TechnologyWuhan 430205China Wuhan National Laboratory for Optoelectronics(WNLO) School of Optical and Electronic InformationSchool of Integrated CircuitsHuazhong University of Science and TechnologyWuhan 430074China

Lead selenide(PbSe)colloidal quantum dots(CQDs)are suitable for the development of the next-generation of photovoltaics(PVs)because of efcient multiple-exciton generation and strong charge coupling *** date,the reported high-efcient PbSe CQD PVs use spin-coated zinc oxide(ZnO)as the electron transport layer(ETL).However,it is found that the surface defects of ZnO present a difculty in completion of passivation,and this impedes the continuous progress of *** address this disadvantage,fuoride(F)anions are employed for the surface passivation of ZnO through a chemical bath deposition method(CBD).The F-passivated ZnO ETL possesses decreased densities of oxygen vacancy and a favorable band *** from these improvements,PbSe CQD PVs report an efciency of 10.04%,comparatively 9.4%higher than that of devices using sol-gel(SG)ZnO as *** are optimistic that this interface passivation strategy has great potential in the development of solution-processed CQD optoelectronic devices.

关键词： Zinc oxide Surface passivation Band alignment Quantum-dot solar cells

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

一种高效的分布式相似短文本聚类算法

计算机与数字工程 2016年第5期44卷 895-900,943页

作者：原默晗唐晋韬王挺国防科学技术大学计算机学院长沙410073

近似重复在微博等网络短文本中十分常见,查找和消除近似重复对于网络信息的有效处理具有非常重要的意义。论文针对相似短文本聚类的特点,在改进shingling、最小哈希和局部敏感哈希算法相结合的文件相似检测方法的基础上,设计了一个高效... 详细信息

近似重复在微博等网络短文本中十分常见,查找和消除近似重复对于网络信息的有效处理具有非常重要的意义。论文针对相似短文本聚类的特点,在改进shingling、最小哈希和局部敏感哈希算法相结合的文件相似检测方法的基础上,设计了一个高效的短文本聚类方法。该方法通过将文本表示成连续短字符串集合,并应用最小哈希将集合简化成一组由数字组成的文本签名,通过局部敏感哈希算法得到符合相似度条件的文本聚类。为了适应网络信息规模大的特点,论文进一步利用Apache Spark集群计算框架对聚类算法进行了并行化,提高了数据处理的效率,并分析了影响算法性能的因素。

关键词：文本聚类最小哈希局部敏感哈希 shingling Spark

Au nanoclusters suppress chronic lymphocytic leukaemia cells by inhibiting thioredoxin reductase 1 to induce intracellular oxidative stress and apoptosis

在线全文

学校读者我要写书评

暂无评论

Science Bulletin 2017年第8期62卷 537-545页

作者： Qiong Li Qing yuan mohan Zhao Yawen Yao Liang Gao Ru Liu Yaling Wang Yong Gong Fuping Gao Xueyun Cao Faculty of Life Science and Technology Kunming University of Science and Technology Kunming 650500 China University of Chinese Academy of Sciences Beijing 100049 China CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China Department of Chemistry and Chemical Engineering Beijing University of Technology Beijing 100124 China Synchrotron Radiation Facility Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China

Chronic lymphocytic leukaemia （CLL） is a rare blood cancer that always relapses as refractory disease and eventually leads to death. To date, therapeutic options for CLL patients are scarce and there is an urgent need to develop novel chemotherapeutics that are both effective and safe. Gold-containing compounds induce a lethal oxidative and endoplasmic reticulum stress response in cultured and primary CLL cells via inhibition of thioredoxin reductase （TrxR）. However, traditional gold-containing medicines have revealed side effects during clinical applications. Therefore, safer gold-containing drugs are needed to overcome this challenge. In this study, a novel peptide templated gold cluster Au2sSv9 was synthesized and its therapeutic effect on CLL cells was evaluated. This nanocluster could induce cell apoptosis in MEC-1 cells in a dose-dependent manner which correlated with the uptake amount of clusters in cells. As expected, increasing intracellular reactive oxidative species （ROS） in MEC-1 cells was exhibited with the increase of cluster dosage. Further analyses demonstrated the underlying mechanism that the nan- oclusters suppress the activity ofTrxR1, increase the level of intracellular ROS, destroy the mitochondrial membrane potential and finally trigger the mitochondrial apoptotic pathway in MEC-1 cells. Furthermore, the direct interaction between Au2sSv9 clusters and TrxRl was confirmed for the first time by isothermal titration calorimetry. These findings explored the preclinical efficacy and potential mech- anism of gold clusters in CLL therapy and provided a fundamental reference for the development of other novel gold-containing chemotherapeutics to treat CLL.

关键词： Chronic lymphocytic leukaemia (CLL) Gold nanoclusters Thioredoxin reductase (TrxR) Mitochondrial membrane potential (MMP) Apoptosis

基于智慧教学平台超声医学SRV混合式教学模式探索

在线全文

学校读者我要写书评

暂无评论

医学教育研究与实践 2024年第4期32卷 423-427页

作者：董沫含栗艳杨晓丁雷袁佳妮刘瑾罗文空军军医大学西京医院医务处陕西西安710032 空军军医大学西京医院药剂科陕西西安710032 空军军医大学西京医院超声科陕西西安710032 空军军医大学西京医院影像医学教研室陕西西安710032

混合式教学是超声医学临床教学改革的必由之路。利用智慧教学平台的多种信息化技术,设计构建针对超声医学的“智能-远程-虚拟”(Smart-Remote-Virtual,SRV)混合式教学模式。利用智能化模块实施“基础-图像-临床”探究式教学,培养整合思... 详细信息

混合式教学是超声医学临床教学改革的必由之路。利用智慧教学平台的多种信息化技术,设计构建针对超声医学的“智能-远程-虚拟”(Smart-Remote-Virtual,SRV)混合式教学模式。利用智能化模块实施“基础-图像-临床”探究式教学,培养整合思维能力;利用远程实景教学,将理论与实践结合,培养实践运用能力;利用虚拟仿真模块,拓展实践训练时空。教学实践问卷调查显示,基于智慧教学平台的超声医学SRV混合式教学模式促进学习能力提升,提高课堂教学效果。

关键词：智慧教室混合式教学远程教学虚拟仿真教学超声医学

在线全文

学校读者我要写书评

暂无评论

基于文献与专家咨询的中医体质舌象特征研究

安徽中医药大学学报 2024年第3期43卷 8-12页

作者：陈泽杰郑燕飞周开林高源郭怡阳武默涵侯淑涓北京中医药大学中医学院北京100029 北京中医药大学国家中医体质与治未病研究院北京100029 北京中医药大学人文学院北京100029

目的构建中医体质舌象特征条目池并评价其在体质辨识中的贡献度。方法梳理现有文献中中医体质的舌象特征,构建特征条目池,采用德尔菲法专家咨询形成专家共识。结果通过22篇文献构建了9种体质104项舌象特征条目池,在此基础上,专家对舌象... 详细信息

目的构建中医体质舌象特征条目池并评价其在体质辨识中的贡献度。方法梳理现有文献中中医体质的舌象特征,构建特征条目池,采用德尔菲法专家咨询形成专家共识。结果通过22篇文献构建了9种体质104项舌象特征条目池,在此基础上,专家对舌象特征在中医体质辨识的重要性进行打分,形成7种体质20项的专家共识条目,总体评价均值为8.13分,其中血瘀质(8.76分)、痰湿质(8.53分)、湿热质(8.42分)和阴虚质(8.39分)表现出较高的贡献度。结论不同体质具有不同的舌象特征,舌象特征对体质辨识具有一定的指导意义,但通过舌象区分体质类型具有一定的难度。

关键词：中医体质舌象特征德尔菲法专家共识

Mps1 dimerization and multisite interactions with Ndc80 complex enable responsive spindle assembly checkpoint signaling

在线全文

学校读者我要写书评

暂无评论

Journal of Molecular Cell Biology 2020年第7期12卷 486-498页

作者： Ping Gui Divine M.Sedzro Xiao yuan Sikai Liu mohan Hei Wei Tian Najdat Zohbi Fangwei Wang Yihan Yao Felix O.Aikhionbare Xinjiao Gao Dongmei Wang Xuebiao Yao Zhen Dou MOE Key Laboratory of Membraneless Organelle and Cellular Dynamics Hefei National Laboratory for Physical Sciences at the MicroscaleSchool of Life SciencesUniversity of Science and Technology of ChinaHefei 230027China Keck Center for Cellular Dynamics and Organoids Plasticity Morehouse School of MedicineAtlantaGA 30310USA Key Laboratory of Molecular Biophysics of the Ministry of Education College of Life Science and TechnologyHuazhong University of Science and TechnologyWuhan 430074China Life Sciences Institute and Innovation Center for Cell Signaling Network Zhejiang UniversityHangzhou 310058China

Error-free mitosis depends on accurate chromosome attachment to spindle microtubules,which is monitored by the spindle assembly checkpoint(SAC)*** an upstream factor of SAC,the precise and dynamic kinetochore localization of Mps1 kinase is critical for initiating and silencing SAC ***,the underlying molecular mechanism remains ***,we demonstrated that the multisite interactions between Mps1 and Ndc80 complex(Ndc80C)govern Mps1 kinetochore ***,we identified direct interaction between Mps1 tetratricopeptide repeat domain and *** further identified that Mps1 C-terminal fragment,which contains the protein kinase domain and C-tail,enhances Mps1 kinetochore ***,Mps1 C-terminal fragment mediates its *** of C-tail attenuates the kinetochore targeting and activity of Mps1,leading to aberrant mitosis due to compromised SAC *** together,our study highlights the importance of Mps1 dimerization and multisite interactions with Ndc80C in enabling responsive SAC signaling.

关键词： mitosis spindle assembly checkpoint kinetochore Mps1 kinase Ndc80 complex

侧卧位对骨质疏松性椎体压缩性骨折病人单侧PKP骨水泥分布的影响

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

实用老年医学 2024年第4期38卷 367-371页

作者：白云峰李明哲宋睿嘉袁若婷雷智轩史默涵曹书畅吴涛南京市第二医院骨科江苏省南京市210003 南京医科大学第二附属医院骨科江苏省南京市210011 南京医科大学第二临床医学院江苏省南京市211166

目的研究侧卧位对骨质疏松性椎体压缩性骨折(OVCF)病人单侧经皮椎体球囊扩张后凸成形术(PKP)骨水泥分布的影响。方法对2018年1月至2022年1月在我院脊柱外科行单侧PKP治疗的OVCF病人进行回顾性分析。根据骨水泥注入过程中使用的体位将病... 详细信息

目的研究侧卧位对骨质疏松性椎体压缩性骨折(OVCF)病人单侧经皮椎体球囊扩张后凸成形术(PKP)骨水泥分布的影响。方法对2018年1月至2022年1月在我院脊柱外科行单侧PKP治疗的OVCF病人进行回顾性分析。根据骨水泥注入过程中使用的体位将病人分为侧卧位组和俯卧位组,比较2组治疗及随访期间的影像学和症状指标。结果本研究共纳入190例病人,94例病人接受侧卧位水泥注射(侧卧位组),96例病人接受俯卧位水泥注射(俯卧位组)。2组病人术后症状和影像学指标均明显改善。与俯卧位组相比,术后1周,侧卧位组的VAS评分显著降低(P<0.05)。与俯卧位组相比,侧卧位组骨水泥分布分级更优(P<0.05),水泥渗漏率较低(13.8%比26.0%,P<0.05)。最后一次随访时,侧卧位组对侧椎体高度高于俯卧位组[(18.3±1.08)mm比(17.4±1.03)mm,P<0.05]。结论侧卧位可有效改善单侧PKP病人的骨水泥分布,更好地缓解急性疼痛,降低骨水泥渗漏发生率及远期对侧椎体高度塌陷程度。

关键词：侧卧位经皮椎体球囊扩张后凸成形术水泥分布骨质疏松性椎体压缩性骨折

N,S-CQDs/Mn_(0.5)Cd_(0.5)S的制备及光催化产氢性能

在线全文

学校读者我要写书评

暂无评论

河北师范大学学报（自然科学版） 2024年第2期48卷 141-149页

作者：杨沫寒贾子璇袁晓张旭红河北师范大学化学与材料科学学院河北石家庄050024

采用水热法制备了氮、硫共掺杂碳量子点(N,S-CQDs),并用超声辅助法合成了N,S-CQDs修饰的Mn_(0.5)Cd_(0.5)S(MCS)复合光催化材料.研究表明,在模拟太阳光照射下,质量分数为1%的N,S-CQDs/MCS的光催化产氢速率显著提高,为34159.25μmol/(g·... 详细信息

采用水热法制备了氮、硫共掺杂碳量子点(N,S-CQDs),并用超声辅助法合成了N,S-CQDs修饰的Mn_(0.5)Cd_(0.5)S(MCS)复合光催化材料.研究表明,在模拟太阳光照射下,质量分数为1%的N,S-CQDs/MCS的光催化产氢速率显著提高,为34159.25μmol/(g·h),是MCS的1.63倍,是质量分数为1%的CQDs/MCS的1.14倍.此复合物光催化产氢性能的提高主要归因于N,S-CQDs优异的电子迁移能力以及MCS与N,S-CQDs之间的紧密接触.

关键词： N,S共掺杂碳量子点 Mn_(0.5)Cd_(0.5)S 光催化剂产氢

Interfacial engineering of heterogeneous molecular electrocatalysts using ionic liquids towards efficient hydrogen peroxide production

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Catalysis 2022年第5期43卷 1238-1246页

作者： Zixun Yu Chang Liu Yeyu Deng mohan Li Fangxin She Leo Lai yuan Chen Li Wei School of Chemical and Biomolecular Engineering The University of SydneyDarlingtonNew South WalesAustralia

Efficient and selective oxygen reduction reaction(ORR)electrocatalysts are critical to realizing decentralized H_(2)O_(2)production and *** we demonstrate a facile interfacial engineering strategy using a hydrophobic ionic liquid(IL,i.e.,[BMIM][NTF2])to boost the performance of a nitrogen coordinated single atom cobalt catalyst(i.e.),cobalt phthalocyanine(CoPc)supported on carbon nanotubes(CNTs).We find a strong correlation between the ORR performance of CoPc/CNT and the thickness of its IL *** characterization revealed that a higher O_(2)solubility(2.12×10^(−3)mol/L)in the IL compared to aqueous electrolytes provides a local O2 enriched surface layer near active catalytic sites,enhancing the ORR ***,the hydrophobic IL can efficiently repel the as‐synthesized H_(2)O_(2)molecules from the catalyst surface,preventing their fast decomposition to H_(2)O,resulting in improved H_(2)O_(2)*** to CoPc/CNT without IL coatings,the catalyst with an optimal~8 nm IL coating can deliver a nearly 4 times higher mass specific kinetic current density and 12.5%higher H2O2 selectivity up to 92%.In a two‐electrode electrolyzer test,the optimal catalyst exhibits an enhanced productivity of 3.71 molH2O2 gcat^(–1)h^(–1),and robust *** IL‐based interfacial engineering strategy may also be extended to many other electrochemical reactions by carefully tailoring the thickness and hydrophobicity of IL coatings.

关键词： Hydrogen peroxide Ionic liquid Oxygen reduction reaction Single‐atom catalyst Heterogeneous molecular catalyst