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Ethmoidal Polyposis, Adenoid Hypertrophy and Tympanic Membrane Perforation—A Case Report

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International Journal of Otolaryngology and Head & Neck Surgery 2024年第3期13卷 178-186页

作者： Ahmad Mahmud mohammed Bello Fufore abubakar Umar Hamisu Abdullahi Thomas Musa Samdi Auwal Adamu Onyekwere George B. Nwaorgu Department of Otorhinolaryngology Modibbo Adama University/Modibbo Adama University Teaching Hospital Yola Nigeria Department of Otorhinolaryngology Bayero University/Aminu Kano Teaching Hospital Kano Nigeria National Ear Care Centre (NECC) Kaduna Nigeria Department of ENT Abubakar Tafawa Balewa Teaching Hospital Bauchi Nigeria Department of ENT Federal University of Health Sciences Azare Bauchi Nigeria Department of Otorhinolaryngology University College Hospital Ibadan/College of Medicine University of Ibadan Ibadan Nigeria

Background: Ethmoidal polyposis coexisting with adenoid enlargement and tympanic membrane perforation is a rare condition in otolaryngological practice. Evidences have shown that antrochoanal polyp often times coexists with adenoid enlargement especially in the young which was in sharp contrast to ethmoidal polyposis occurring in the presence of adenoid enlargement. Moreover, the hidden location of nasopharynx housing the adenoids, coupled with the masking effect of bilateral sinonasal polyps, leads to inadvertent misdiagnosis of this complex pathology with subsequent difficulty in providing effective management. Case Presentation: A 24 year-old lady presented with recurrent bilateral nasal obstruction that became persistent associated with nasal discharge and anosmia. She also had recurrent right otorrhoea with associated hearing loss. Diagnostic rigid nasal endoscopy revealed mucoid discharge with bilateral polypoid masses filling both nasal cavities. Otoendoscopic finding revealed a small (about 5%) central tympanic membrane perforation. A clinical assessment of chronic rhinosinusitis with nasal polyposis complicated by chronic suppurative otitis media (CSOM) was made. A non-contrast CT scan of the paranasal sinuses showed isodense lesions in the nasal cavities, all paranasal sinuses and the entire nasopharynx. She had endoscopic sinus surgery and a nasopharyngeal clearance biopsy. The nasal, paranasal and nasopharyngeal masses had histologic confirmation of inflammatory nasal polyps and lymphoid (adenoid) hyperplasia respectively. Her condition improved remarkably with subsequent medical treatment. She was followed up for 8 months and no recurrence was observed. Conclusion: Sinonasal polyposis can coexist with adenoid hypertrophy and middle ear disease as a single pathological condition. Hence, a high index of suspicion and thorough evaluation become necessary for making timely diagnoses and instituting effective management.

关键词： Sino-Nasal Polyps Adenoid Enlargement Rhinosinusitis Otitis Media Endoscopic Sinus Surgery

Techno-Economic Analysis of a Grid-Connected Waste to Energy Gasification Plant:A Case Study

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Energy Engineering 2021年第6期118卷 1681-1701页

作者： Ahmed abubakar Elwan mohammed Hafiz Habibuddin Department of Electrical Power Engineering Universiti Teknologi MalaysiaJohor Bahru81310Malaysia

With population growth around the world,municipal waste disposal and continued energy demand becomes some of the major challenges to deal *** order to address these,an approach is required for an optimal waste management system that offers the population benefit with a lower environmental *** study evaluates the technical-economic and environmental impact analysis of a grid-connected waste to energy(WtE)plant to power a Univerisiti Teknologi Malaysia(UTM)*** energy recovery potential of the waste stream was assessed using the life cycle assessment(LCA)method with GaBi^(TM) software(version 4).A technical,economic and environmental analysis was then carried out for the grid-connected WtE system using HOMERPro software with gasification conversion *** cash flow analysis was based on levelized costs of energy(LCOE)and total net present value(NPV).The results gave an NPV for the system at USD 1.11×10^(7),with most of the effects resulting from the grid operating costs and the LCOE of USD 0.43/kWh compared to the grid unit price of USD 0.7/kWh which corresponds to a saving of$0.27/kWh in energy *** an environmental point of view,the results showed a significant reduction in carbon dioxide emissions from around 2,000 tons per year to around 400 tons per *** regard to the amount of waste sent to landfills,the results show a significant improvement from 142,605.5 kg/year to 0.13 kg/year.

关键词： Waste to energy techno-economic analysis solid waste gasification

Quartz dissolution in a single phase-high pH Berea sandstone via alkaline injection

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Energy Geoscience 2021年第3期2卷 181-188页

作者： Abdullah Musa Ali mohammed Yerima Kwaya abubakar Mijinyawa Department of Geology Bayero University Kano(BUK)KanoNigeria

A common assertion is that alkaline solution aids oil mobilization by generating in situ soap,or by lowering interfacial tension(IFT)to ultra-low values in synergy with *** study takes a different approach that involves the alkaline dissolution of detrital quartz grains of sandstone reservoirs to create pathways for oil migration and *** dissolution via alkaline injection will result in changes in permeability and *** study performed high-pH core flooding on Berea sandstones using core displacement *** molybdate spectrophotometry was applied to measure the amount of dissolved *** and confining pressure variations were also *** molar concentration of NaOH varied at 0.5 M and 1.0 *** results show higher initial silica dissolution for 0.5 M NaOH(˃200mg/L)compared to 1.0 M NaOH(20 mg/L),which can be attributed to the presence of pre-existing dissolved silica and precipitates in the system prior to the first injection ***,a steady quartz dissolution rate of 0.4 mg/L/hr for 20 h was only achieved at 1.0 ***,an abrupt drop in quartz dissolution to below 0 mg/L was recorded for 0.5 M NaOH after 3 h of *** higher molar concentration of injected alkaline solution,both confining and inlet pressures increased from 8 and 5 bars to 12 and 11 bars as a result of the increased secondary phase of(hydr)oxides or precipitates in the ***,it can be inferred that the effect of alkaline solution on quartz dissolution is strongly dependent on molar concentration.

关键词： Alkaline injection Core flooding Dissolved silica Quartz Petroleum recovery

Conditional Heteroscedasticity in Streamflow Process: Paradox or Reality?

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Open Journal of Modern Hydrology 2012年第4期2卷 79-90页

作者： Martins Yusuf Otache Isiguzo Edwin Ahaneku abubakar sadeeq mohammed John Jiya Musa Department of Agricultural & Bioresources Engineering Federal University of Technology Minna Nigeria

The various physical mechanisms governing the dynamics of streamflow processes act on a seemingly wide range of temporal and spatial scales;almost all the mechanisms involved present some degree of nonlinearity. Against the backdrop of these issues, in this paper, attempt was made to critically look at the subject of Autoregressive Conditional Heteroscedasticity (ARCH) or volatility of streamflow processes, a form of nonlinear phenomena. Towards this end, streamflow data (both daily and monthly) of the River Benue, Nigeria were used for the study. Results obtained from the analyses indicate that the existence of conditional heteroscedasticity in streamflow processes is no paradox. Too, ARCH effect is caused by seasonal variation in the variance for monthly flows and could partly explain same in the daily streamflow. It was also evident that the traditional seasonal Autoregressive Moving Average (ARMA) models are inadequate in describing ARCH effect in daily streamflow process though, robust for monthly streamflow;and can be removed if proper deseasonalisation pre-processing was done. Considering the findings, the potential for a hybrid Autoregressive Moving Average (ARMA) and Generalised Autoregressive Conditional Heteroscedasticity (GARCH)type models should be further explored and probably embraced for modelling daily streamflow regime in view of the relevance of statistical modelling in hydrology.

关键词： Autoregressive Heteroscedasticity Homoscedasticity Volatility Nonlinear Dynamics

Antihyperglycaemic activity of ethylacetate extract of Chlorophytum alismifolium in type 2 diabetes:The involvement of peroxisome proliferator-activated receptor-γand dipeptidyl peptidase-4

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Journal of Integrative Medicine 2021年第1期19卷 78-84页

作者： Abdulhakim abubakar Abdullahi Balarabe Nazifi Idris mohammed Maje Yusuf Tanko Joseph Akpojo Anuka Ezzeldin Mukthar Abdurahman Department of Pharmacology and Therapeutics Ahmadu Bello UniversityZaria PMB-1044Nigeria Department of Pharmacology and TherapeuticsBayero UniversityKano PMB-3011Nigeria Department of Human PhysiologyAhmadu Bello UniversityZaria PMB-1044Nigeria Department of Pharmacognosy and Drug DevelopmentAhmadu Bello UniversityZaria PMB-1044Nigeria

Objective:This research is to investigate the antihyperglycaemic activity and the underlying mechanisms of action of the ethylacetate extract of Chlorophytum alismifolium(EACA)tubers in a type 2 diabetes ***:The tubers were processed and sequentially extracted in hexane followed by ethylacetate,using a Soxhlet apparatus,and subjected to gas chromatography-mass spectrometry(GC–MS).The acute toxicity of EACA was investigated in albino Wistar *** antihyperglycaemic study was carried out using high-fat diet(pelletized diet and margarine in the ratio of 10:1 and 20%fructose solution)and streptozotocin-induced hyperglycaemic Wistar *** effects of the extract(150,300 and 600 mg/kg)on blood glucose level,insulin,peroxisome proliferator-activated receptor-c(PPAR-c)and dipeptidyl peptidase-4(DPP-4)were evaluated using enzyme-linked immunosorbent ***:The oral median lethal dose in Wistar rats was estimated to be>5000 mg/*** with EACA at all doses significantly reduced the fasting blood glucose levels,compared to the hyperglycaemic control,and over *** of EACA increased the serum insulin and PPAR-c levels while decreasing DPP-4 ***–MS analysis revealed the presence of 13 compounds,with isothiazole and isoxazolidine covering total area of 24.6%and 22.69%,***:The findings from this study showed that EACA has important compounds with beneficial effect in type 2 diabetes and acts by increasing insulin secretion and PPAR-c level and decreasing DPP-4 activity.

关键词： Chlorophytum alismifolium Diabetes mellitus Gas chromatography-mass spectrometry Insulin Peroxisome proliferator-activated receptor-c Dipeptidyl-peptidase 4

Saponins-rich fraction of Calotropis procera leaves elicit no antitrypanosomal activityin a rat model

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Asian Pacific Journal of Tropical Biomedicine 2013年第7期3卷 569-572页

作者： mohammed Auwal Ibrahim abubakar Babando Aliyu Kayode Meduteni Isa Yunusa Departments of 1Biochemistry Zaria Nigeria Departments of Chemistry Ahmadu Bello UniversityZaria Nigeria Department of Biochemistry Kano University of Science and TechnologyWudil Nigeria

Objective:To examine thein vitroandin vivoanti-Trypanosoma evansi(***)activity ofsaponins-rich fraction ofCalotropis procera(cpsf)leaves as well as the effect of the fraction onthe parasite-induced ***:A 60-minutes time course experiment was conductedwith various concentrations of the fraction using a 96-well microtiter plate technique,andsubsequently used to treat *** rats at 100 and 200 mg/kg *** of anemia was analyzed in all animals during the ***:The cpsfdid not demonstrate anin vitroantitrypanosomal ***,the cpsf treatments did notsignificantly(P>0.05)keep the parasites lower than the infected untreated *** the end ofthe experiment,*** rats developed anemia whose severity was not significantly(P>0.05)ameliorated by the cpsf ***:It was concluded that saponins derivedfromCalotropis proceraleaves could not elicitin vitroandin vivoactivities ***.

关键词： Anemia Asclepiadaceae Calotropis procera saponins Trypanosoma evansi

Prevalence and risk factors associated with malaria infection among pregnant women in a semi-urban community of north-western Nigeria

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Infectious Diseases of Poverty 2015年第1期4卷 193-197页

作者： Sani Abdullahi Fana mohammed Danladi abubakar Bunza Sule Aliyu Anka Asiya Umar Imam Shehu Usman Nataala Author details 1 Department of Medical Microbiology Faculty of Medical Laboratory ScienceUsmanuDanfodiyo UniversitySokotoNigeria Department of Biological Sciences UsmanuDanfodiyo UniversitySokotoNigeria

Background:Malaria during pregnancy remains a serious public health problem,with substantial risks for the mother,her foetus and the *** aim of this study was to determine the prevalence of malaria and possible risk factors for malaria infection among pregnant women in a semi-urban area in north-western *** women are among the most susceptible to malaria *** of their malaria infection status is an important yardstick to measure the effectiveness of any malaria control ***:We conducted a cross sectional study in the semi-urban area of Argungu,Kebbi State *** hundred and fifty five pregnant women were included in the study after informed verbal consent was *** each participant,the socio-demographic profile,stage of pregnancy and attitude to the use of insecticide-treated nets(ITNs)were investigated using a *** blood samples were collected and thick blood smears were prepared and stained with Giemsa stains to check for malaria *** associations between age,education level and use of ITNs with occurrence of malaria infection during pregnancy were analysed using the chi-square ***:One hundred and six(41.6%)out of 255 pregnant women were infected with malaria parasites,with a mean parasite density of 800 parasitesμl−*** was found that prevalence and parasite density decreased as age *** chi-square test indicated that a lack of education and non-usage of ITNs were significantly associated with malaria ***:Malaria is still a major public health issue among pregnant women mainly due to illiteracy and non-compliance to using *** awareness about malaria preventive measures and early attendance of antenatal care services will help to reduce malaria and,consequently,its associated morbidities and mortalities.

关键词： Malaria Pregnant women Mean parasite density Prevalence Risk factors Giemsa stain Argungu

Groundwater Vulnerability and Sensitivity Optimization Using Geographical Information System for Kano Metropolis, North-Western Nigeria

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Journal of Geoscience and Environment Protection 2022年第4期10卷 202-226页

作者： Zaharatu mohammed Babika abubakar Ibrahim Tukur Deparrtment of Architecture and Civil Engineering University of Bath Bath United Kingdom Department of Geography Kano University of Science and Technology Kano Nigeria

This paper developed an optimization technique for groundwater vulnerability in Kano Metropolis, North-Western Nigeria. A combination of DRASTIC is taken from initial letters of seven parameters namely depth to water table (D), net recharge (R), aquifer media (A), soil media (S), topography (T), impact of vadose zone (V) and hydraulic conductivity (C), while GOD also represents groundwater confinement (G), overlaying strata (O), depth of water (D) and multi-criteria evaluation (MCE) techniques were used in the optimization method by integrating other important and sensitive parameters for groundwater pollution, principally the anthropogenic point source pollution parameters (dump site, petroleum stations, automobile shops and under storage tanks). Geographic Information System was used to perform the sensitivity analysis (SA) using the single parameter and map removal sensitivity methods. Result of sensitivity optimization revealed the depth to groundwater (D), net recharge (N), impact of vadose zone (V) from DRASTIC model, and groundwater conferment (G) from GOD model having significant impact on the groundwater vulnerability, respectively. A combination of these four parameters was used to generate DNVG groundwater vulnerability for the area. This suggests that an integration of other point source pollution parameters can enhance the influence of DRASTIC and GOD model parameters on groundwater vulnerability condition. The paper recommends for the application of the optimization method used in this study in another area with similar geological and anthropogenic point source of pollution with a view to validating or improving on it. In this study, several input data, such as anthropogenic point sources of contamination, are added to the existing DRASTIC and GOD model parameters as part of a sensitivity analysis aiming to optimise the performance of the resultant models.

关键词： Groundwater Pollution Sensitivity Modelling Optimization

The Incorporation of Precautionary Principle in the Planning of Global System for Mobile Communications Mast Locations in Built-up Areas： Proposals for Jimeta, Nigeria

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Journal of Earth Science and Engineering 2014年第5期4卷 284-294页

作者： mohammed abubakar Husain Abdurrahman Belel Ismaila Department of Urban and Regional Planning Modibbo Adama University of Technology P.M.B. 2076 Yola Nigeria

This paper aimed at incorporating the precautionary principles into the planning and development of GSM （global system for mobile communications） masts within the built-up areas of Jimeta. Using GIS （geographic information system） analysis technique, the zone of precautionary principle was defined to 500 meters radius as the zone within which precautionary measures are exercised. The criteria for siting GSM base station are also equally identified. For instance, the presence of certain elements within the precautionary zone like schools, hospitals, residential density and overlap of RF （radio frequency） occurrences, may disqualify any mast location. Analysis of the land use within precautionary zone has shown various proportions of exposure to RF, whereas, only 3.39% of the masts are suitably located and 94.92% are not and therefore should be relocated. The study recommend measures for addressing physical development within precautionary areas, including land conversion and mast sharing to reduce potential harmful effects of RF emanating from GSM base stations.

关键词： Precautionary principle GSM mast locations RF in built-up areas.