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The global stability and optimal control of the COVID-19 epidemic model

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International Journal of Biomathematics 2024年第1期17卷 1-28页

作者： Fengsheng Chien Hassan Saberi Nik mohammad Shiraziant J.F.Gomez-Aguilar School of Finance and Accounting Fuzhou University of International Studies and Trade Fuzhou 352020 P.R.China Faculty of Business City university of Macao Macao 999078P.R.China Department of Mathematics and Statistics University of Neyshabur NeyshaburIran CONACyT-Tecnologico Nacional de Mécico/CENIDET Interior Internado Palmira S/N Col.Palmira C.P.62490CuernavacaMorelosMérico

This paper considers stability analysis of a Susceptible-Exposed-Infected-Recovered-Virus(SEIRV)model with nonlinear incidence rates and indicates the severity and weakness of control factors for disease *** Lyapunov function using Volterra-Lyapunov matrices makes it possible to study the global stability of the endemic equilibrium *** optimal control strategy is proposed to prevent the spread of coronavirus,in addition to governmental *** objective is to minimize together with the quantity of infected and exposed individuals while minimizing the total costs of treatment.A numerical study of the model is also carried out to investigate the analytical results.

关键词： Global stability SEIRV epidemic model dynamical systems Volterra-Lyapunov stability optimal control

Insight into small eyes: a practical description from phenotypes presentations to the management

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International Journal of Ophthalmology(English edition) 2024年第2期17卷 380-391页

作者： Sana Niazi Sorcha NíDhubhghaill Farideh Doroodgar Zisis Gatzioufas mohammad Hossein Dehghan Translational Ophthalmology Research Center Tehran University of Medical SciencesTehran ***Iran Antwerp University Hospital Edegem 2650Belgium Faculty of Health Sciences Antwerp UniversityAntwerpen 2000EdegemBelgium Negah Aref Ophthalmic Research Center Shahid Beheshti University of Medical SciencesTehran 16666Iran University Eye Hospital Basel Basel 4031Switzerland

This narrative review aimed to have an algorithmic approach to microphthalmos by a systematic *** definition can be related to a number of special *** the more challenging cases of complex microphthalmos,relative anterior microphthalmos,and nanophthalmos,the surgeon can approach these cases more safely if they have a deep understanding of the anatomical variations and ideal formulae for intraocular lens computation and knows how to avoid intra-and post-operative *** this article,we review the criteria by which we recognize and describe pre-,intra-,and post-operative considerations,as well as discuss the ideal intraocular lenses for microphthalmos,given the intricate varieties of small eye phenotypes.

关键词： microphthalmos nanophthalmos lenses intraocular anterior chamber axial length eye cataract microcornea syndrome

Thermodynamic Performance Analysis of Geothermal Power Plant Based on Organic Rankine Cycle (ORC) Using Mixture of Pure Working Fluids

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Energy Engineering 2024年第8期121卷 2023-2038页

作者： Abdul Sattar Laghari mohammad Waqas Chandio Laveet Kumar Mamdouh El Haj Assad Department of Mechanical Engineering Mehran University of Engineering and TechnologyJamshoro76062Pakistan Department of Mechanical and Industrial Engineering College of EngineeringQatar UniversityDoha00000Qatar Sustainable&Renewable Energy Engineering Department University of SharjahSharjah00000United Arab Emirates

The selection of working fluid significantly impacts the geothermal ORC’s *** a mixture as a working fluid is a strategy to improve the output of geothermal *** the current study,modelling and thermodynamic analysis of ORC,using geothermal as a heat source,is carried out at fixed operating *** model is simulated in the Engineering Equation Solver(EES).An environment-friendly mixture of fluids,i.e.,R245fa/R600a,with a suitable mole fraction,is used as the operating *** mixture provided the most convenient results compared to the pure working fluid under fixed operating *** impact of varying the evaporator pressure on the performance parameters,including energy efficiency,exergy efficiency and net power output is *** system provided the optimal performance once the evaporator pressure reached the maximum *** efficiencies:Energy and Exergy,and Net Power output of the system are 16.62%,64.08%and 2199 kW for the basic cycle and 20.72%,67.76%and 2326 kW respectively for the regenerative cycle.

关键词： Organic rankine cycle internal heat exchanger moderate-temperature geothermal source mixture of the fluid exergy

Beyond bacteria:Role of non-bacterial gut microbiota species in inflammatory bowel disease and colorectal cancer progression

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World Journal of Gastroenterology 2024年第36期30卷 4078-4082页

作者： Hania Haque Syeda Warisha Zehra mohammad Shahzaib Saif Abbas Nazish Jaffar of Medicine Jinnah Sindh Medical UniversityKarachi 75510SindhPakistan Department of Pathology Jinnah Sindh Medical UniversityKarachi 75510SindhPakistan

This letter emphasizes the need to expand discussions on gut microbiome’s role in inflammatory bowel disease(IBD)and colorectal cancer(CRC)by including the often-overlooked non-bacterial components of the human gut *** highlights how viral,fungal and archaeal inhabitants of the gut respond towards gut dysbiosis and contribute to disease *** such as bacteriophages target certain bacterial species and modulate the immune *** viruses found associated include Epstein-Barr virus,human papillomavirus,John Cunningham virus,cytomegalovirus,and human herpes simplex virus type *** such as Candida albicans and Malassezia contribute by forming tissue-invasive filaments and producing inflammatory cytokines,***,mainly methanogens are also found altering the microbial fermentation *** correspondence,thus underscores the significance of considering the pathological and physiological mechanisms of the entire spectrum of the gut microbiota to develop effective therapeutic interventions for both IBD and CRC.

关键词： Gut microbiota Colorectal cancer Inflammatory bowel disease Dysbiosis Bacteriophages Methanogens Fungi

Gut microbiota predicts the diagnosis of ulcerative colitis in Saudi children

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World Journal of Clinical Pediatrics 2024年第1期13卷 118-124页

作者： mohammad El Mouzan Ahmed Al Sarkhy Asaad Assiri Department of Pediatrics Gastroenterology UnitKing Saud UniversityRiyadh 11461Saudi Arabia

BACKGROUND Ulcerative colitis(UC)is an immune-mediated chronic inflammatory condition with a worldwide *** the etiology of this disease is still unknown,the understanding of the role of the microbiota is becoming increasingly *** To investigate the predictive power of the gut microbiota for the diagnosis of UC in a cohort of newly diagnosed treatment-naïve Saudi children with *** The study population included 20 children with a confirmed diagnosis of UC and 20 healthy *** DNA was extracted and sequenced,and shotgun metagenomic analysis was performed for bacteria and *** and bioinformatics demonstrated significant dysbiosis in the form of reduced alpha diversity,beta diversity,and significant difference of abundance of taxa between children with UC and control *** receiver operating characteristic curve,a probability curve,was used to determine the difference between the UC and control *** area under the curve(AUC)represents the degree of separability between the UC group and the control *** AUC was calculated for all identified bacterial species and for bacterial species identified by the random forest classification algorithm as important potential biomarkers of UC.A similar method of AUC calculation for all bacteriophages and important species was *** The median age and range were 14(0.5-21)and 12.9(6.8-16.3)years for children with UC and controls,respectively,and 40%and 35%were male for children with UC and controls,*** AUC for all identified bacterial species was 89.5%.However,when using the bacterial species identified as important by random forest classification algorithm analysis, the accuracy increased to 97.6%. Similarly, the AUC for all theidentified bacteriophages was 87.4%, but this value increased to 94.5% when the important bacteriophagebiomarkers were *** very high to excellent AUCs of fecal bacterial and viral species sugge

关键词： Ulcerative colitis Microbiota Area under the curve Children Saudi Arabia

Modeling functional brain connections in methamphetamine and opioid abusers

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Medicine in Novel Technology and Devices 2024年第1期21卷 88-96页

作者： Nasimeh Marvi Javad Haddadnia mohammad Reza Fayyazi Bordbar Hakim Sabzevari University SabzevarIran Psychiatry and Behavioral Sciences Research Center Mashhad University of Medical SciencesMashhadIran

Substance abuse has become a significant problem *** primary purpose of this study was to model the functional brain connectivity in methamphetamines(Meth)and opioids(Op)groups in comparison with the healthy control(HC)*** data were recorded in Meth(n=8),Op(n=12),and HC groups(n=12)in a closed-eye resting *** NeuCube model based on a spiking neural network was used for EEG data's functional brain connectivity *** NeuCube model was evaluated quantitatively and qualitatively with model descriptive *** results showed the average value of the neuron's activation level,spikes emitted from neurons,and clustering coefficient as a communication parameter in the HC group decreased from 1154,1103,0.026 to 1036,981,0.020 in the Op group and to 511,468,0.009 in the Meth group,*** changes in indices were significant according to the ANOVA test with p〈*** decrease in indices was more significant in the Meth group than in the Op *** research findings showed that the abuse of Meth and Op causes damage to the brain's functional *** damage included shortening and limiting communication routes and decreased neurons'ability to generate membrane potential and emit inhibitory and excitatory *** were reported to be more severe in the Meth group than in the Op group.

关键词： Electroencephalogram Methamphetamines NeuCube model Opioids Spiking neural networks

Global systematic review and meta-analysis of knowledge, attitudes, and practices towards dengue fever among the general population

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Asian Pacific Journal of Tropical Medicine 2024年第5期17卷 191-207,I0001-I0003页

作者： Abdolreza Sotoodeh Jahromi mohammad Jokar Arman Abdous Nader Sharifi Tahere Abbasi Vahid Rahmanian Zoonoses Research Center Jahrom University of Medical SciencesJahromIran Faculty of Veterinary Medicine Karaj BranchIslamic Azad UniversityKarajIran Department of Public Health Khomein University of Medical SciencesKhomeinIran Research Center for Social Determinants of Health Jahrom University of Medical SciencesJahromIran Department of Public Health Torbat Jam Faculty of Medical SciencesTorbat JamIran

Objective:To determine the global level of knowledge,attitudes,and practices towards dengue fever among the general ***:To complete this systematic review and meta-analysis,a thorough search for pertinent English-language literature was undertaken during the study's extension until October *** search used Google Scholar,Scopus,PubMed/MEDLINE,Science Direct,Web of Science,EMBASE,Springer,and ProQuest.A quality assessment checklist developed using a modified Newcastle-Ottawa Scale for the cross-sectional study was used to evaluate the risk of bias in the included *** variance and Cochran Q statistics were employed in the STATA software version 14 to assess study *** there was heterogeneity,the Dersimonian and Liard random-effects models were ***:59 Studies totaling 87353 participants were included in this *** investigations included 86278 participants in 55 studies on knowledge,20196 in 33 studies on attitudes,and 74881 in 29 studies on *** pooled estimates for sufficient knowledge,positive attitudes,and dengue fever preventive behaviors among the general population were determined as 40.1%(95%CI 33.8%-46.5%),46.8%(95%CI 35.8%-58.9%),and 38.3%(95%CI 28.4%-48.2%),*** exhibits the highest knowledge level at 63.5%,and Africa shows the lowest at 20.3%.Positive attitudes are most prevalent in the Eastern Mediterranean(54.1%)and Southeast Asia(53.6%),contrasting sharply with the Americas,where attitudes are notably lower at 9.05%.Regarding preventive behaviors,the Americas demonstrate a prevalence of 12.1%,Southeast Asia at 28.1%,Western Pacific at 49.6%,Eastern Mediterranean at 44.8%,and Africa at 47.4%.Conclusions:Regional disparities about the knowledge,attitude and preventive bahaviors are evident with Europe exhibiting the highest knowledge level while Africa has the *** findings emphasize the importance of targeted public health interventions tailored to regional

关键词： Break-bone fever Knowledge Attitudes Practices

Exploring the meaning of care among lived experiences of patients with blindness:an interpretive phenomenological study

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Frontiers of Nursing 2024年第3期11卷 319-326页

作者： mohammad Ali mohammadi Mehdi Heidarzadeh Saeed Mehri Mahmood Shamshiri Department of Medical-Surgical Nursing School of Nursing and MidwiferyArdabil University of Medical SciencesArdabil ***Iran Department of Emergency Nursing School of Nursing and MidwiferyArdabil University of Medical SciencesArdabil ***Iran Department of Critical Care Nursing School of Nursing and MidwiferyArdabil University of Medical SciencesArdabil ***Iran

Objective:To explore the meaning of care experienced by people with blindness in ***:Interpretive phenomenology along with the 6-step method of van Manen was used to conduct the *** purposeful sampling,15 people with legal blindness were *** analysis was used to isolate the meaning of ***:Five themes emerged:(a)nurses in the eyes of patients with blindness;(b)negligence in the caring moments;(c)being cared for in ambiguity;(d)Uncoordinated care;and(e)Psychological discomfor *** sub-themes were condensed into an overarching theme titled as“marginalized patients inside the stereotypical healthcare system.”Conclusions:Lived experiences of patients with blindness revealed that hospitals provide stereotypic or inappropriate care for this minority group in *** professionals par ticularly nurses should be skilled to provide person-centered and coordinated care for patients with blindness.

关键词： hospitalization lived experience meaning of care people with blindness phenomenology

Effects of relaxation breathing exercise on fatigue and cortisol level among Indonesian gynecological cancer patients undergoing chemotherapy:a pilot study

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Frontiers of Nursing 2024年第2期11卷 201-208页

作者： Mulhaeriah Mulhaeriah mohammad Syafar Sangkala Syahrul Syahrul Rezki Wahyuni Department of Maternity Nursing Faculty of NursingHasanuddin UniversityMakassarSouth Sulawesi 90245Indonesia Department of Medical Surgical Nursing Faculty of NursingHasanuddin UniversityMakassarSouth Sulawesi 90245Indonesia Hasanuddin University Hospital MakassarSouth Sulawesi 90245Indonesia

Objective:This study aimed to determine the effect of the relaxation breathing exercise(RBE)on fatigue and cortisol levels among Indonesian women with gynecological cancer undergoing ***:This pilot study consecutively recruited 44 gynecological cancer patients to receive RBE(22)or usual care(22).Cortisol level was measured before and after completion of the intervention(day 8).Fatigue was measured using the Piper Fatigue Scale(PFS).Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale(HADS)at the baseline days of the study for days 1,4,and *** obtained data were analyzed using Fisher’s exact test,the independent t-test,and the Mann-Whitney U ***:There were significant increases in cortisol levels within the groups,either the intervention or control groups,respectively(P-value=0.0003 and 0.001).Despite there being no statistical significance between the intervention and control groups,there were noticeable differences in the cortisol levels,indicating the extreme increase in cortisol levels in the control group(Median[IQR1-IQR3]:2.30[0.99-9.09];Min-Max:0.43-23.38)compared with the intervention group(Median[IQR1-IQR3]=2.97[1.26-5.18];Min-Max=0.39-6.91).Conclusions:RBE helps prevent a significant increase in cortisol levels that can alleviate fatigue for women with gynecological *** research was recommended to compare several intervention modalities for fatigue and cancer-related symptom management based on cortisol level changes.

关键词： anxiety cortisol fatigue gynecological cancer relaxation breathing exercise