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Molecular and cellular aspects of extramedullary manifestations of acute myeloid leukemia

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Journal of Cancer Metastasis and Treatment 2016年第1期2卷 44-50页

作者： Javad mohammadiasl Abbas Khosravi mohammad Shahjahani Shirin Azizidoost Najmaldin Saki Department of Medical Genetics Faculty of MedicineAhvaz Jundishapur University of Medical SciencesAhvaz ***Iran Health Research Institute Research Center of Thalassemia and HemoglobinopathyAhvaz Jundishapur University of Medical SciencesAhvaz ***Iran

The myeloid extramedullary tumor is a solid tumor formed by infiltration of immature myeloid cells in various tissues of the *** tumor is also identified as chloroma or myeloid sarcoma(MS).MS is a manifestation of acute myeloid leukemia(AML)occurring at presentation or during treatment or *** is associated with multiple chromosomal abnormalities and molecular mutations since patients with these disorders bear a high potential for MS *** is a high incidence of extramedullary infiltration(EMI)in *** patients with EMI have a worse prognosis than patients without *** stem cells and leukemic stem cells reside in a special bone marrow microenvironment called niche,which is essential for their normal *** are exploited dysfunctional cell-cell and matrix-cell interactions,which convert a normal niche into a neoplastic *** study summarizes the current knowledge on the molecular and cellular characteristics of AML with EMI and extramedullary niches in AML patients.

关键词： Acute myeloid leukemia extramedullary infiltration niche

A Measure Theoretical Approach for Path Planning Problem of Nonlinear Control Systems

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Intelligent Control and Automation 2011年第2期2卷 144-151页

作者： Amin Jajarmi Hamidreza Ramezanpour mohammad Dehghan Nayyeri Ali Vahidian Kamyad 不详

This paper presents a new approach to find an approximate solution for the nonlinear path planning problem. In this approach, first by defining a new formulation in the calculus of variations, an optimal control problem, equivalent to the original problem, is obtained. Then, a metamorphosis is performed in the space of problem by defining an injection from the set of admissible trajectory-control pairs in this space into the space of positive Radon measures. Using properties of Radon measures, the problem is changed to a measure-theo- retical optimization problem. This problem is an infinite dimensional linear programming (LP), which is approximated by a finite dimensional LP. The solution of this LP is used to construct an approximate solution for the original path planning problem. Finally, a numerical example is included to verify the effectiveness of the proposed approach.

关键词： Path Planning Optimal Control Measure Theory Linear Programming

Assessment of dairy products consumed on the Arakmarket as determined by heavy metal residues

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Health 2014年第5期6卷 323-327页

作者： mohammad Rezaei Hajar Akbari Dastjerdi Hassan Jafari Ali Farahi Arman Shahabi Hossein Javdani Hossein Teimoory mohammad Yahyaei Ali Akbar Malekirad Arak University of Medical Sciences Arak Iran Department of Biology Payame Noor University Tehran Iran Department of Food Safety and Hygiene School of Public Health Tehran University of Medical Sciences (TUMS) Tehran Iran Department of New Sciences and Technologies Life Science Engineering Group University of Tehran Tehran Iran Department of Veterinary School of Veterinary Shahid Bahonar University of Kerman Kerman Iran Soren Tech Toos Laboratory Food & Biotechnology North East Town Toos Industrial Town Mashhad Iran

Dairy products are nutritious drink and can play a significant part in a healthy diet. The safety of dairy products decreases with increasing concentration of toxic compounds and environmental pollutants (especially heavy metals). In the present study, the contamination of Al, Sn, As, Cd, Hg and Pb in dairy products (pasteurized milk, yogurt, yogurt drink, cheese) consumed in Arak, Iran, 2013 was evaluated using inductively coupled plasma mass spectrometry (ICP-SFMS) method. To meet the aim, 60 samples of 5 different brands, consisting of pasteurized milk, yogurt, yogurt drink, cheese (n = 15) were selected and analyzed for heavy metals content. 100% of the samples were positive regarding the total average and range concentration of Al, Sn, As, Cd, Hg and Pb in dairy products was 168.25 ± 92.2 (30.6 - 356.5), 5.9 ± 4 (1.1 - 16), 3.2 ± 1.95 (0.4 - 8.1), 4.55 ± 2.6 (0.6 - 10.6), 23.15 ± 10.4 (6.8 - 50.2) and 15.4 ± 8.53 (3.1 - 40.2) μg/kg, respectively. 28.3% (17 of 60 samples) of dairy products samples had lead (Pb) greater than EU limit and national Iranian standard (20 μg/kg). Statistical analysis indicated except about As in pasteurized milk and cheese there was no significant difference between products in terms of heavy metals content.

关键词： Heavy Metals Milk Cheese Yogurt Food Safety ICP

前房注射0.1%莫西沙星联合结膜下注射曲安奈德预防超声乳化术后感染（英文）

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国际眼科杂志 2018年第10期18卷 1757-1762页

作者： Suzan Amana Rattan Najah Kadhum mohammad Mahir Kadhim Mutashar 巴格达大学Al-kindy医学院手术室伊拉克巴格达AL-Nahdhasquare10001 巴格达大学医学院手术室伊拉克巴格达BabAL-Moadhamsquare10001 Al-Wazyrea 眼专科私立医院伊拉克巴格达10001

目的:评估前房注射0.1%莫西沙星联合结膜下注射4 mg曲安奈德预防白内障超声乳化术后感染和炎症的疗效,并与局部滴药组比较。方法:共纳入1000例,平均年龄38～70岁,全部行超声乳化术的患者分为两组,两组在年龄、术前眼压(IOP)和中心黄斑厚... 详细信息

目的:评估前房注射0.1%莫西沙星联合结膜下注射4 mg曲安奈德预防白内障超声乳化术后感染和炎症的疗效,并与局部滴药组比较。方法:共纳入1000例,平均年龄38～70岁,全部行超声乳化术的患者分为两组,两组在年龄、术前眼压(IOP)和中心黄斑厚度(CMT)方面无显著差异,分别为P=0.6,P=0.9和P=0.8。对照组患者500例,术后1mo每日4次局部应用0.5%盐酸莫西沙星和0.1%地塞米松滴眼液。研究组在手术结束时,前房注入0.1%莫西沙星0. 4 m L联合4 mg曲安奈德结膜下注射。随访时间为术后1d、1wk、1mo和3mo。检查4次前房反应,测量3次眼压,最后一次测量CMT。结果:该临床试验研究中两组人群分别应用不同的预防方法,两组无眼内炎病例发生。通过两样本t检验,术后1d,研究组前房细胞显著低于对照组,而术后1wk、1mo和3mo两组间无统计学差异。在第3mo随访时,两组间眼压和中心黄斑厚度无明显差异。对照组炎症发生率为9.6%,研究组为4%。对照组在1mo时眼压升高≥10 mmHg患者占2. 4%,显著高于研究(0.8%)。结论:白内障术后联合应用前房内莫西沙星和结膜下曲安奈德可有效预防感染和炎症,并且大多数(480例)患者不需其它任何外用药物,这为患者节省了成本,并帮助降低无法实施局部用药的病人并发症的几率与依从性差的患者术后不良药物反应。

关键词：盐酸莫西沙星曲安奈德超声乳化

Nonlinear Seismic Response of Steel Concentrically Braced Frames Using Endurance Time Analysis Method

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Journal of Civil Engineering and Architecture 2011年第9期5卷 847-855页

作者： mohammad Amin Hariri Ardebili Yashar Zarringhalam Masoud Mirtaheri Mahmood Yahyai Department of Civil Engineering K. N. Toosi University of Technology Tehran Iran

In present paper application of Endurance Time Analysis （ETA） method in nonlinear seismic assessment of steel concentrically braced frames is studied. In this method structure is subjected to a set of predesigned increasing acceleration functions and various responses of the structure are recorded during synthetic seismic excitation. The averages of maximum values for various responses in Nonlinear Time-History Analyses （NTHA） extracted from real ground motions are expected to be close to those obtained from ETA up to equivalent target time. For this purpose a set of 9, 11, 13 and 15 stories steel frames were designed and plastic hinge method was selected as source of nonlinearity in all cases. Responses were compared based on interstory drift ratio and story shear in two methods and results show satisfactory consistency between two methods. Finally, it was concluded that the ETA method can be used as alternative method in nonlinear seismic analysis of concentrically braced steel frames.

关键词： Endurance time analysis concentrically braced frames nonlinear seismic assessment.

The University of Jordan E-Learning Platform: State, Students’ Acceptance and Challenges

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Journal of Software Engineering and Applications 2014年第12期7卷 999-1007页

作者： Tamara Almarabeh Hiba mohammad Rana Yousef Yousef Kh. Majdalawi Department of Computer Information Systems King Abdullah II School for Information Technology The University of Jordan Amman Jordan

The rapid changes and increased complexity in today’s world present new challenges and put new demands on the education system. There has been generally a growing awareness of the necessity?to change and improve the existing system towards online learning. Jordan is one of the distinguished countries in the Middle East with rapid progress in education and with advanced teaching and learning technologies. The University of Jordan is trying to exploit Information and Communication Technology (ICT) in education and moving forward by introducing the latest E-learning management systems (LMSs) to keep pace of technological revolution in the higher education. It is?important to find out the impact of E-learning management system in the University of Jordan,?examine the students’ acceptance for this new system and address the challenges facing the students while using the E-learning management system and these are what this paper is trying to do.

关键词： Moodle E-Learning Blackboard Technology Acceptance Model Jordan

Satisfaction of Adult Patients about Their Smile Aesthetics Compared to Dental Professionals Observation

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Open Journal of Stomatology 2016年第11期6卷 236-244页

作者： Basil Yousef Alamassi mohammad Saleh Al Onazi Ahmad Abdullah Al Zoman Department of Restorative Dentistry Riyadh Colleges of Dentistry and Pharmacy Riyadh Saudi Arabia Department of Dentistry Security Force Hospital Riyadh Saudi Arabia

Objective: The aim of the present study was to evaluate personal satisfaction of adult dental patients about their smiles aesthetics in comparison to dental professionals view. Method: One hundred twenty adult patients (76 male and 44 female) visiting the screening clinics of Riyadh colleges of dentistry and Pharmacy were asked to evaluate their smiles by completing a questionnaire containing five questions concerning five aesthetic elements which are: Overall smile;color;shape;alignment of their teeth;and appearance of their gum during smiling. They were asked to rate each of the five categories in Visual Analog Scale (VAS) graded from 0 to 10. A smiling photograph was taken for each patient to be evaluated by two restorative specialists using the same scale. Patients and dental professional mean evaluation scores were statistically analyzed for any significant differences. Result: The average age of the patients was 39.1 years. The mean patients’ satisfaction with their own smiles was [6.47] on the VAS which was statistically higher than the average of dentists’ evaluation scores [4.95] (p Conclusion: Patients’ satisfaction about their dental aesthetics was statistically higher than the dental professional assessments. Dental professionals appear to be more critical in their evaluation of patients smile aesthetics. Age showed no significant relation with the level of satisfaction while gender and reason of dental visit showed a significant relation with patients smile satisfaction.

关键词： Dental Aesthetic Satisfaction Smile Perception

Neutrophil Count, Platelet Indices, CRP and Their Association with Disease Activity of Juvenile Idiopathic Arthritis (JIA): A Study from Bangladesh

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Open Journal of Rheumatology and Autoimmune Diseases 2023年第1期13卷 41-49页

作者： Sanjida Pervin Sonia Ellen Ferdous mohammad Imnul Islam Shahana Akhter Rahman Medical Officer National Institute of Cardiovascular Diseases Sher E Bangla Nagar Dhaka Bangladesh Department of Paediatrics Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh

Background: Chronic inflammation of the joints in JIA patients is associated with raised levels of serum inflammatory biomarkers, which vary according to disease activity. Neutrophil count, platelet count, mean platelet volume (MPV), platelet distribution width (PDW), ESR and CRP are the essential markers to evaluate the disease activity status of JIA patients. Objectives: To assess neutrophil count, platelet count, MPV, PDW, CRP and Juvenile Arthritis Disease Activity Score (JADAS) in JIA patients and determine their association at the initial visit and six months after treatment. Methods: This prospective observational study was conducted from March 2019 to December 2020 in the department of paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. Fifty newly diagnosed JIA cases fulfilling the ILAR classification criteria were included in the study. Disease activity was assessed by JADAS 27. JADAS 27 and inflammatory biomarkers were measured at the initial visit and six months of treatment and these were compared. Results: Mean neutrophil count, platelet count, and CRP significantly decreased at follow-up after six months of treatment. MPV and PDW were increased after six months compared to the initial visit, and the change was significant. Mean JADAS 27 also decreased significantly at follow-up. Neutrophil count, Platelet indices and CRP had a significant association with JADAS 27. Conclusion: In this study, neutrophil count, platelet indices, and CRP after six months of treatment were improved. A significant association of JADAS 27 was found with platelet indices, neutrophil count and CRP.

关键词： Arthritis Chronic Inflammation Inflammatory Biomarkers

Recovery of Image through Alamouti Channel with Incorporation of RSA Algorithm

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Journal of Computer and Communications 2016年第2期4卷 1-10页

作者： Aninda Majumder mohammad Raihan Ruhin Tahsina Hashem Md. Imdadul Islam Department of Computer Science and Engineering Jahangirnagar University Dhaka Bangladesh

In many applications, it is necessary to transmit images at a remote station, where wired Internet service is not available. In this case, wireless local loop (WLL) can help in making wireless link between one end node of the internet and remote service center. In such link, the communication is heavily affected by large and small scale fading;hence the received signal experiences huge distortion in case of forward error correction. Otherwise, huge service delay arises due to frequent negative acknowledgements. To combat the situation, we can choose Alamouti channel of full rate and fully orthogonal space-time block code (OSTBC). Our aim is to transmit images through Alamouti channel and to observe the quality of the recovered image, in context of bit error rate (BER). We have also observed the impact of fading and additive white Gaussian noise (AWGN) on the image without application of error correction or detection technique of channel coding. To ensure security, we apply the RSA algorithm on each pixel prior transmitting and decrypt them at the receiving end, where we found no impairment from the algorithm. Finally, we observe that the relative performance of the system changes digital modulation schemes.

关键词： Quotient and Remainder Matrix Alamouti Simulator Multiple-Input Single-Output (MISO) Image Encryption and Decryption BER and Discrete Wavelet Transform (DWT)