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Development of anti-corrosive coating on AZ31 Mg alloy modified by MOF/LDH/PEO hybrids

Journal of Magnesium and Alloys 2024年第2期12卷 586-607页

作者： Muhammad Ali Khan Ananda Repycha Safira mohammad Aadil Mosab Kaseem Corrosion and Electrochemistry Laboratory Department of Nanotechnology and Advanced Materials EngineeringSejong UniversitySeoul 05006Republic of Korea

The self-assembly of hybrid inorganic-organic materials on stationary platforms plays a critical role in improving their structural stability and wide *** this work,a novel two-step hydrothermal approach is proposed for synthesizing stable and advanced hybrid coatings on metal-oxide platforms through the surface modification of layered double hydroxide(LDH)films using novel metal-organic frameworks(MOFs).Initially,Mg-Al LDH nanocontainers,grown on a magnesium oxide layer produced through plasma electrolytic oxidation(PEO)of AZ31 Mg alloy substrate,were intercalated with cobalt via an oxidation route,providing the metallic coordination center for the MOF *** the subsequent step,a pioneering technique is introduced,utilizing tryptophan as the organic linker for the first time at a pH of *** self-assembly of cobalt-tryptophan complex,driven by the strong bonding between electrophilic sites of monomers and nucleophilic sites,facilitated the formation of a MOF network having a cloud-like structure on the surface of MgAl LDH's *** resulting MOF-LDH encapsulation containers demonstrate exceptional electrochemical stability when exposed to a 3.5 wt.%NaCl solution,surpassing the performance of PEO and pure LDH *** enhanced stability is attributed to the development of a dense top layer and a stable composition within the self-assembled MOF,effectively sealing flaws and preventing the infiltration of corrosive ions into the underlying metallic *** formation mechanism of MOFs on LDH galleries is investigated using density functional theory calculations.

关键词： Mg alloy Layered double hydroxide Metal-organic frameworks Corrosion DFT

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RoGRUT: A Hybrid Deep Learning Model for Detecting Power Trapping in Smart Grids

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Computers, Materials & Continua 2024年第5期79卷 3175-3192页

作者： Farah mohammad Saad Al-Ahmadi Jalal Al-Muhtadi Center of Excellence in Information Assurance(CoEIA) King Saud UniversityRiyadh11543Saudi Arabia College of Computer&Information Sciences King Saud UniversityRiyadh11543Saudi Arabia

Electricity theft is a widespread non-technical issue that has a negative impact on both power grids and electricity *** hinders the economic growth of utility companies,poses electrical risks,and impacts the high energy costs borne by *** development of smart grids is crucial for the identification of power theft since these systems create enormous amounts of data,including information on client consumption,which may be used to identify electricity theft using machine learning and deep learning ***,there also exist different solutions such as hardware-based solutions to detect electricity theft that may require human resources and expensive ***-based solutions are presented in the literature to identify electricity theft but due to the dimensionality curse,class imbalance issue and improper hyper-parameter tuning of such models lead to poor *** this research,a hybrid deep learning model abbreviated as RoGRUT is proposed to detect electricity theft as amalicious and non-malicious *** key steps of the RoGRUT are data preprocessing that covers the problem of class imbalance,feature extraction and final theft *** advanced-level models like RoBERTa is used to address the curse of dimensionality issue,the near miss for class imbalance,and transfer learning for *** effectiveness of the RoGRUTis evaluated using the dataset fromactual smartmeters.A significant number of simulations demonstrate that,when compared to its competitors,the RoGRUT achieves the best classification *** performance evaluation of the proposed model revealed exemplary results across *** accuracy achieved was 88%,with precision at an impressive 86%and recall reaching 84%.The F1-Score,a measure of overall performance,stood at 85%.Furthermore,themodel exhibited a noteworthyMatthew correlation coefficient of 78%and excelled with an area under the curve of 91%.

关键词： Electricity theft smart grid RoBERTa GRU transfer learning

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Randomization Strategies in Image Steganography Techniques:A Review

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Computers, Materials & Continua 2024年第8期80卷 3139-3171页

作者： AFM Zainul Abadin Rossilawati Sulaiman mohammad Kamrul Hasan Center for Cyber Security Faculty of Information Science and TechnologyUniversiti Kebangsaan Malaysia(UKM)BangiSelangor43600Malaysia Department of Information and Communication Engineering Pabna University of Science and TechnologyPabna6600Bangladesh

Image steganography is one of the prominent technologies in data hiding *** system performance mostly depends on the embedding *** goal is to embed strictly confidential information into images without causing perceptible changes in the original *** randomization strategies in data embedding techniques may utilize random domains,pixels,or region-of-interest for concealing secrets into a cover image,preventing information from being discovered by an *** implementation of an appropriate embedding technique can achieve a fair balance between embedding capability and stego image imperceptibility,but it is challenging.A systematic approach is used with a standard methodology to carry out this *** review concentrates on the critical examination of several embedding strategies,incorporating experimental results with state-of-the-art methods emphasizing the robustness,security,payload capacity,and visual quality metrics of the stego *** fundamental ideas of steganography are presented in this work,along with a unique viewpoint that sets it apart from previous works by highlighting research gaps,important problems,and ***,it offers a discussion of suggested directions for future study to advance and investigate uncharted territory in image steganography.

关键词： Information hiding image steganography randomized embedding techniques payload capacity imperceptibility

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Hippo-YAP/TAZ signaling in breast cancer:Reciprocal regulation of microRNAs and implications in precision medicine

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Genes & Diseases 2024年第2期11卷 760-771页

作者： Farzad Sadri Seyede fatemeh hosseini Zohreh Rezaei mohammad Fereidouni Student Research Committee Birjand University of Medical SciencesBirjand ***Iran Tabas School of Nursing Birjand University of Medical SciencesBirjand ***Iran Department of Biology University of Sistan and BaluchestanZahedan ***Iran Cellular and Molecular Research Center Birjand University of Medical SciencesBirjand ***Iran

Breast cancer is a molecularly heterogeneous disease and the most common female *** recent years,therapy approaches have evolved to accommodate molecular diversity,with a focus on more biologically based therapies to minimize negative *** regulate cell fate in human breast cells,the Hippo signaling pathway has been associated with the alpha subtype of estrogen *** pathway regulates tissue size,regeneration,and healing,as well as the survival of tissue-specific stem cells,proliferation,and apoptosis in a variety of organs,allowing for cell *** signaling is mediated by the kinases MST1,MST2,LATS1,and LATS2,as well as the adaptor proteins SAV1 and *** kinases phosphorylate the downstream effectors of the Hippo pathway,yes-associated protein(YAP),and transcriptional coactivator with PDZ-binding motif(TAZ),suppressing the expression of their downstream target *** Hippo signaling pathway kinase cascade plays a significant role in all *** the principles of this kinase cascade would prevent the occurrence of breast *** recent years,small noncoding RNAs,or microRNAs,have been implicated in the development of several malignancies,including breast *** interconnections between miRNAs and Hippo signaling pathway core proteins in the breast,on the other hand,remain poorly *** this review,we focused on highlighting the Hippo signaling system,its key parts,its importance in breast cancer,and its regulation by miRNAs and other related pathways.

关键词： Breast cancer Hippo signaling Large tumor suppressor kinase 1 microRNAs PDZ-binding motif Yes-associated protein

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Chain Rule for Extracting Resilience Procurement Costs from Locational Marginal Prices

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CSEE Journal of Power and Energy Systems 2024年第3期10卷 1342-1355页

作者： Yifei Wang Tong Zhu Tiancong Chen mohammad Shahidehpour Qingshan Xu College of Electrical Engineering Southeast UniversityNanjing 210096China Henan Mechanical&Electrical Vocational College Xinzheng 451191China Illinois Institute of Technology ChicagoIllinois 60616USA IEEE CSEE

Power system resilience procurement costs in N-k contingencies have gained more prominence as number of extreme events continues to increase.A chain rule is presented in this paper for extracting resilience procurement costs from a fully decomposed locational marginal price(LMP)***,power transfer distribution factor(PTDF)matrices with AC power flow(i.e.,AC-PTDF)are ***-PTDF and AC-LODF(line outage distribution factor)equations are derived for N-k contingencies and a fully decomposed LMP model is developed where generation and transmission security components are established for specific ***,resilience procurement costs can be measured at different buses for the proposed security *** of N-k contingencies on resilience procurement costs at specific buses can be determined as proposed security components will gain more insight for resilience procurement in power *** modified IEEE 6-bus and 118-bus systems are adopted to verify effectiveness of the proposed resilience procurement method.

关键词： Line outage distribution factors locational marginal price power system resilience power transfer distribution factor security components

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Two-dimensional MOF-based materials:Preparations and applications as electrodes in Li-ion batteries

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Journal of Energy Chemistry 2024年第10期97卷 388-418页

作者： Narges Nobakht Seyyed Ahmad Etghani mohammad hosseini Seyed Hamed Aboutalebi Condensed Matter National Laboratory Institute for Research in Fundamental Sciences Batt Scout Company School of Biological Sciences Institute for Research in Fundamental Sciences

Two-dimensional(2D) metal-organic frameworks(MOFs) are rapidly emerging as a unique class of mushrooming family of 2D materials offering distinctive features,such as hierarchical porosity,extensive surface area,easily available active sites,and versatile,adaptable *** promising characteristics have positioned them as highly appealing alternatives for a wide range of applications in energy storage technologies,including lithium ***,the poor conductivity and limited stability of 2D MOFs have limited their real applications in electrochemical energy *** limitations have therefore warranted ongoing research to enhance the performance of 2D *** the significance of 2D MOF-based materials as an emerging class of advanced materials,a multitude of strategy has been devised to address these challenges such as synthesizing 2D conductive MOFs and derivatives along with 2D MOF *** promising approach involves the use of 2D MOF derivatives,including transition metal oxides,which due to their abundant unsatu rated active metal sites and shorter diffusion paths,offer superior electrochemical ***,by combining pristine 2D MOFs with other materials,hybrid 2D MOF materials can be *** hybrids,with their enhanced stability and conductivity,can be directly utilized as active materials in lithium *** the present review,we categorize 2D MOF-based materials into three distinct groups:pristine 2D MOFs,2D MOFderived materials,and 2D MOF hybrid *** synthesis methods for each group,along with their specific applications as electrode materials in lithium-ion batteries,are discussed in *** comprehensive review provides insights into the potential of 2D MOFs while highlighting the opportunities and challenges that are present in this evolving field.

关键词： 2D materials 2D metal-organic frameworks Energy storage Li-ion batteries Synthesis

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Effects of grain's shape-and size-polydispersities,orientation,and area fraction on tortuosity and permeability of 2D granular media

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Particuology 2024年第7期90卷 535-557页

作者： Ke Cao Huisu Chen mohammad Iqbal Khan Mingqi Li Lin Liu Jiangsu Key Laboratory of Construction Materials School of Materials Science and EngineeringSoutheast UniversityNanjing 211189China Department of Civil Engineering College of EngineeringKing Saud UniversityP.O.Box 800Riyadh 11421Saudi Arabia School of Civil and Transportation Engineering Hebei University of TechnologyTianjin 300401China College of Civil and Transportation Engineering Hohai UniversityNanjing210098China

The microstructure of granular media, including grain's shape- and size-polydispersities, orientation, and area fraction can potentially affect its permeability. However, few studies consider the coupling effects of these features. This work employs geometrical probability and stereology to establish quantitative relationships between the above microstructural features and the geometric tortuosity of the two-dimensional granular media containing superellipse, superoval, and polygon grains. Then the lattice Boltzmann method (LBM) is used to determine the permeabilities of these granular media. By combining the tortuosity model and the LBM-derived permeabilities, modified K–C equations are formulated to predict the permeability and the shape factor, considering the grain's shape- and size-polydispersities, orientation, and area fraction. The reliability of these methods can be verified by comparing them with both our simulations and available experimental, theoretical, and numerical data reported in the literature. The findings implicate that the tortuosity and permeability of the granular media are strongly correlated with the grain's shape, orientation, and area fraction but unaffected by the size polydispersity and spatial arrangement of grains. Only circularity is not enough to derive a unified formula for considering the impact of grain shape on tortuosity and permeability, other shape parameters need to be explored in the future.

关键词： Geometric tortuosity Konzey-Carman equation Shape and size ploydispersities Grain orientation Lattice Boltzmann method Granular media

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New insights into the therapeutic approaches for the treatment of tauopathies

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Neural Regeneration Research 2024年第5期19卷 1020-1026页

作者： Himanshi Singh Asmita Das mohammad Moshahid Khan Tayebeh Pourmotabbed Department of Microbiology Immunology and BiochemistryUniversity of Tennessee Health Science CenterMemphisTNUSA Department of Biotechnology Delhi Technological UniversityShahbad DaulatpurDelhiIndia Department of Neurology College of MedicineUniversity of Tennessee Health Science CenterMemphisTNUSA Neuroscience Institute University of Tennessee Health Science CenterMemphisTNUSA Center for Muscle Metabolism and NeuropathologyDivision of Regenerative and Rehabilitation Sciences and Department of Physical TherapyCollege of Health ProfessionsUniversity of Tennessee Health Science CenterMemphisTNUSA

Tauopathies are a group of neurological disorders,including Alzheimer’s disease and frontotemporal dementia,which involve progressive neurodegeneration,cognitive deficits,and aberrant tau protein *** development of tauopathies cannot currently be stopped or slowed down by treatment *** the significant contribution of tau burden in primary tauopathies and the strong association between pathogenic tau accumulation and cognitive deficits,there has been a lot of interest in creating therapies that can alleviate tau pathology and render neuroprotective ***,small molecules,immunotherapies,and gene therapy have been used to reduce the pathological tau burden and prevent neurodegeneration in animal models of ***,the major pitfall of the current therapeutic approach is the difficulty of drugs and gene-targeting modalities to cross the blood-brain barrier and their unintended side *** this review,the current therapeutic strategies used for tauopathies including the use of oligonucleotide-based gene therapy approaches that have shown a promising result for the treatment of tauopathies and Alzheimer’s disease in preclinical animal models,have been discussed.

关键词： dementia gene therapies immunotherapy neurodegeneration oligonucleotides tau tauopathies therapies

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The Effect of Spironolactone Loading on the Properties of 3D-Printed Polycaprolactone/Gold Nanoparticles Composite Scaffolds for Myocardial Tissue Engineering

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Journal of Bionic Engineering 2024年第2期21卷 924-937页

作者： Sharareh Ghaziof Shahrokh Shojaei Mehdi Mehdikhani mohammad Khodaei Milad Jafari Nodoushan Department of Biomedical Engineering Central Tehran BranchIslamic Azad UniversityTehran***Iran Stem Cells Research Center Tissue Engineering and Regenerative Medicine InstituteCentral Tehran BranchIslamic Azad UniversityTehran***Iran Department of Biomedical Engineering Faculty of EngineeringUniversity of IsfahanIsfahan***Iran Materials Engineering Group Golpayegan College of EngineeringIsfahan University of TechnologyGolpayegan87717-67498Iran Hard Tissue Engineering Research Center Tissue Engineering and Regenerative Medicine InstituteCentral Tehran BranchIslamic Azad UniversityTehran***Iran

Engineered cardiac constructs(ECC)aid in the progression of regenerative medicine,disease modeling and targeted drug delivery to adjust and aim the release of remedial combination as well as decrease the side effects of *** this research,polycaprolactone/gold nanoparticles(PCL/GNPs)three-dimensional(3D)composite scaffolds were manufactured by 3D printing using the fused deposition modeling(FDM)method and then coated with gelatin/spironolactone(GEL/SPL).Scanning electron microscopy(SEM)and Fourier transform-infrared spectroscopy(FTIR–ATR)were applied to characterize the ***,drug release,biodegradation,behavior of the myoblasts(H9C2)cell line,and cytotoxicity of the 3D scaffolds were *** microstructural observation of the scaffolds reported interconnected pores with 150–300µm in *** 3D scaffolds were degraded significantly after 28 days of immersion in stimulated body fluid(SBF),with the maximum rate of GEL-coated 3D *** release from cross-linked GEL coating demonstrated the excess of drug release over time,and according to the control release systems,the drug delivery systems(DDS)went into balance after the 14th *** addition,cell culture study showed that with the addition of GNPs,the proliferation of(H9C2)was enhanced,and with GEL/SPL coating the cell attachment and viability were improved *** findings suggested that PCL/GNPs 3D scaffolds coated with GEL/SPL can be an appropriate choice for myocardial tissue engineering.

关键词： Polycaprolactone Gold nanoparticles Drug delivery systems Spironolactone Cell behavior Myoblasts

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Suspended particulate matter promotes epithelial-to-mesenchymal transition in alveolar epithelial cells via TGF-β1-mediated ROS/IL-8/SMAD3 axis

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Journal of Environmental Sciences 2024年第7期141卷 139-150页

作者： Shahrzad Molavinia Dian Dayer mohammad Javad Khodayar Gholamreza Goudarzi Maryam Salehcheh Cellular and Molecular Research Center Medical Basic Sciences Research InstituteAhvaz Jundishapur University of Medical SciencesAhvazIran Department of Toxicology School of PharmacyAhvaz Jundishapur University of Medical SciencesAhvazIran Student Research Committee Ahvaz Jundishapur University of Medical SciencesAhvazIran Toxicology Research Center Medical Basic Sciences Research InstituteAhvaz Jundishapur University of Medical SciencesAhvazIran Air Pollution and Respiratory Diseases Research Center Ahvaz Jundishapur University of Medical SciencesAhvazIran Iranian Scientific Association of Clean Air TehranIran

Epidemiological evidence presents that dust storms are related to respiratory diseases,such as pulmonary fibrosis(PF).However,the precise underlying mechanisms of SPM-elicited adverse effects still need to be ***-mesenchymal transition(EMT)process is a characteristic of *** discussed whether suspended particulate matter(SPM)is involved in EMT induction via transforming growth factor-β1(TGF-β1).In this study,a detailed elemental analysis(55 elements),particle size,and morphology were *** investigate the toxicity of SPM,an MTT test was performed to detect cell ***,A549cells were exposed to selected concentrations of SPM(20 and 40μg/mL)for single and repeated *** DCFH-DA assay showed that exposure to SPM could produce reactive oxygen species(ROS).The ELISA assay demonstrated increased levels of interleukin-8(IL-8)and TGF-β1 in the *** blot was used to detect the expression of proteins associated with EMT and the SMAD3-dependent *** of western blot demonstrated that E-cadherin was reduced,whereas p-SMAD3,vimentin,andα-smooth muscle actin were *** findings indicated that SPM triggered EMT by induction of oxidative stress,inflammation,and the TGF-β1/SMAD3 pathway activation.

关键词： Particulate matter TGF-β1 Oxidative stress Epithelial-mesenchymal transition Pulmonary fibrosis Cells

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