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Fatal cases in pediatric patients after post-exposure prophylaxis for rabies:A report of two cases

Asian Pacific Journal of Tropical Medicine 2024年第1期17卷 39-42页

作者： Hekmatollah Khoubfekr mohammad Jokar Vahid Rahmanian Hasan Blouch mohammad reza shirzadi Rouzbeh Bashar Department of Public Health Iranshahr University of Medical SciencesIranshahrIran Faculty of Veterinary Medicine Karaj BranchIslamic Azad UniversityKarajIran Department of Public Health Torbat Jam Faculty of Medical SciencesTorbat JamIran Center for Communicable Diseases Control Ministry of Health and Medical EducationTehranIran WHO Collaborating Center for Reference and Research on Rabies Virology DepartmentPasteur Institute of IranTehranIran

Rationale:Rabies is a zoonotic disease with a high mortality,primarily transmitted through the bite of infected mammals,particularly dogs and *** being a well-known disease since ancient times,it continues to cause a significant number of human deaths worldwide,with approximately 65000 fatalities reported *** concerns:We present two fatal cases of rabies in a 12-year-old immigrant boy and a 7-year-old *** first case was subject to a 24-hour delay in receiving appropriate medical attention and rabies preventive measures due to the lack of awareness among emergency hospital staff,leading to the administration of wound dressing *** second case received timely rabies immunoglobulin administration;however,there was a 4-day delay in administering the fourth dose of the rabies vaccine,despite presenting evident symptoms of ***:Postmortem examination of brain samples from both patients confirmed the presence of rabies ***:Post-exposure prophylaxis for ***:Both patients were admitted to the hospital after the manifestation of rabies-related symptoms,with the 12-year-old child seeking medical care 47 days after the animal bite and the 7-year-old child seeking medical care 58 days after the ***,the first patient died after 27 days and the second patient died after 40 days of ***:There is an urgent need for heightened awareness and education among both healthcare professionals and the public regarding the urgency of seeking immediate medical attention after potential rabies *** recognition and initiation of post-exposure prophylaxis are pivotal in preventing the progression of the *** surveillance and reporting systems,coupled with continuous training for healthcare professionals,can contribute to early detection and management of rabies cases.

关键词： Rabies Encephalitis Pediatric patients Rabies prophylaxis Public health awareness

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Phenology and population dynamics of sand flies in a new focus of visceral leishmaniasis in Eastern Azarbaijan Province,North western of Iran

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Asian Pacific Journal of Tropical Medicine 2011年第8期4卷 604-609页

作者： Teimour Hazratian Yavar Rassi mohammad Ali Oshaghi mohammad reza Yaghoobi-Ershadi Esmael Fallah mohammad reza shirzadi Sina Rafizadeh Department of Medical Entomology and Vector Control School of Public HeallhTehran University of Medical SciencesTehranIran Department of Parasitology School of MedicineMedical Science/University of TabrizIran Zoonosis Department Ministry of Health& Medical Education Violence and Injury Prevention Safety Promotion Office Emergency Management CenterMinistry of Health & Medical Education

Objective:To investigate species composition,density,accumulated degree-day and diversity of sand flies during April to October 2010 in Azarshahr district,a new focus of visceral leishmaniasis in north western ***:Sand flies were collected using sticky traps biweekly and were stored in 96%*** specimens were mounted in Puri’s medium for species identification using valid keys of *** density was calculated by the formula: number of specimens/m of sticky traps and number of specimens/ number of ***-day was calculated as follows:(Maximum temperature + Minimum temperature)/2—Minimum *** indices of the collected sand flies within different villages were estimated by the Shannon- weaver formula(H’=sum form(i=1) to s Pi log_e Pi ).Results:Totally 5 557 specimens comprising 16 Species(14 Phlebotomus,and 2 Sergentomyia) were *** activity of the species extended from April to *** sand-flies in resting places were Phlebotomus papatasi, Phlebotomus sergenti and Phlebotomus *** monthly average density was 37.***.41.1, 40.23,30.38 and 30.67 for Almalodash,Jaragil,Segaiesh,Amirdizaj and Germezgol villages, *** degree-day from early January to late May was approximately 289 degree *** minimum threshold temperature for calculating of accumulated degree-day was 17.32℃.According on the Shannon-weaver(H’),diversity of sand flies within area study were estimated as 0.917,1.867,1.339,1.673,and 1.562 in Almalodash,Jaragil,Segaiesh,Amirdizaj and Germezgol villages,***:This study is the first detailed research in terms of species composition,density,accumulated degree-day and diversity of sand flies in an endemic focus of visceral leishamaniasis in Azarshahr *** population dynamics of sand flies in Azarshahr district were greatly affected by climatic *** to this study the highest activity of the collected sand fly species occurs at the ter

关键词： Sand fly Visceral leishmaniasis Diversity Degree day Density Iran

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Temperature-jump tensile tests to induce optimized TRIP/TWIP effect in a metastable austenitic stainless steel

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International Journal of Minerals,Metallurgy and Materials 2024年第9期31卷 2025-2036页

作者： mohammad Javad Sohrabi Hamed Mirzadeh Saeed Sadeghpour Abdol reza Geranmayeh reza Mahmudi School of Metallurgy and Materials Engineering College of EngineeringUniversity of Tehran14395-515TehranIran Centre for Advanced Steels Research Materials and Mechanical EngineeringUniversity of Oulu90014 OuluFinland

In the present work,plastic deformation mechanisms were initially tailored by adjusting the deformation temperature in the range of 0 to 200℃ in AISI 304L austenitic stainless steel,aiming to optimize the strength-ductility *** was shown that the combined twinning-induced plasticity(TWIP)/transformation-induced plasticity(TRIP)effects and a wider strain range for the TRIP effect up to higher strains by adjusting the deformation temperature are good strategies to improve the strength-ductility synergy of this metastable stainless *** this regard,by consideration of the observed temperature-dependency of plastic deformation,the controlled sequence of TWIP and TRIP effects for archiving superior strength-ductility trade-off was intended by the pre-designed temperature jump tensile ***,the optimum tensile toughness of 846 MJ/m^(3) and total elongation to 133% were obtained by this strategy via exploiting the advantages of the TWIP effect at 100℃ and the TRIP effect at 25℃ at the later stages of the ***,a deformation-temperature-transformation(DTT)diagram was developed for this metastable ***,based on work-hardening analysis,it was found that the main phenomenon constraining further improvement in the ductility and strengthening was the yielding of the deformation-induced α′-martensite.

关键词： metastable stainless steels transformation-induced plasticity twinning-induced plasticity stacking fault energy mechanical properties

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High-risk spatiotemporal patterns of cutaneous leishmaniasis:a nationwide study in Iran from 2011 to 2020

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Infectious Diseases of Poverty 2023年第3期12卷 93-93页

作者： Neda Firouraghi Robert Bergquist Munazza Fatima Alireza mohammadi Davidson H.Hamer mohammad reza shirzadi Behzad Kiani Department of Medical Informatics School of MedicineMashhad University of Medical SciencesMashhadIran Ingerod BrastadSweden Formerly with the UNICEF/UNDP/World Bank/WHO Special Program for Research and Training in Tropical Diseases World Health OrganizationGenevaSwitzerland Department of Geography The Islamia University of BahawalpurBahawalpurPunjabPakistan Department of Geography and Urban Planning Faculty of Social SciencesUniversity of Mohaghegh ArdabiliArdabilIran Department of Global Health Boston University School of Public HealthBostonMAUSA Section of Infectious Diseases Department of MedicineBoston University School of MedicineBostonMAUSA Center for Disease Control and Prevention(CDC) Iran Ministry of Health&Medical EducationTehranIran Centre de Recherche en SantéPublique Universitéde Montréal7101Avenue du ParcMontréalCanada

Background Cutaneous leishmaniasis(CL)is a wide-reaching infection of major public health *** is one of the six most endemic countries in the *** study aims to provide a spatiotemporal visualization of CL cases in Iran at the county level from 2011 to 2020,detecting high-risk zones,while also noting the movement of high-risk *** On the basis of clinical observations and parasitological tests,data of 154,378 diagnosed patients were obtained from the Iran Ministry of Health and Medical *** spatial scan statistics,we investigated the disease’s purely temporal,purely spatial,spatial variation in temporal trends and spatiotemporal *** P=0.05 level,the null hypothesis was rejected in every *** In general,the number of new CL cases decreased over the course of the 9-year research *** 2011 to 2020,a regular seasonal pattern,with peaks in the fall and troughs in the spring,was *** period of September–February of 2014–2015 was found to hold the highest risk in terms of CL incidence rate in the whole country[relative risk(RR)=2.24,P<0.001)].In terms of location,six signifcant high-risk CL clusters covering 40.6%of the total area of the country were observed,with the RR ranging from 1.87 to *** addition,spatial variation in the temporal trend analysis found 11 clusters as potential high-risk areas that highlighted certain regions with an increasing ***,fve space-time clusters were *** geographical displacement and spread of the disease followed a moving pattern over the 9-year study period afecting many regions of the *** Our study has revealed signifcant regional,temporal,and spatiotemporal patterns of CL distribution in *** the years,there have been multiple shifts in spatiotemporal clusters,encompassing many diferent parts of the country from 2011 to *** results reveal the formation of clusters across counties that cover certain parts of provinces

关键词： Cutaneous leishmaniasis Spatial epidemiology Geographical Information Systems Spatiotemporal analysis SaTScan Spatial scan statistics Neglected tropical diseases Spatiotemporal clustering Iran

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Movement Trend Alterations in the Periaqueductal Gray(PAG)-Employed Ratbot Navigation Are Correlated with Stimulation Parameters

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Journal of Bionic Engineering 2024年第2期21卷 866-876页

作者： Sina Khajei Abed Khorasani mohammad reza Afarinesh Vahid Sheibani Neuroscience Research Center Institute of NeuropharmacologyKerman University of Medical SciencesKerman***Iran Cognitive Neuroscience Research Center Institute of NeuropharmacologyKerman University of Medical SciencesKerman***Iran

In previous studies,Periaqueductal Gray(PAG)stimulation was used to stop ratbots from *** to the homology between the PAG and the intercollicular nucleus,which has been used for forward movement in birds,we investigated the possibility of PAG application to induce forward locomotion for the first *** a corridor maze,the traveled distances via PAG electrical stimulation were examined in nine Wistar male rats during three sessions.A custom-designed stimulator was developed to apply the *** results showed reductions in responses to stimulation over ***,the traveled distances had negative slopes during the consecutive trials(in 8 out of the 9 rats),and the slope mean was significantly different from *** was a strong correlation between the stimulation parameters(electric Charge per Phase(CPP)and the Number of Pulses(NP))and the observed *** negative Movement Slopes(MS)were highly correlated with the CPP and the NP,as the Pearson's linear correlation coefficients were−0.87 and−0.79,*** MS-CPP coefficients of determination(R-squared)were also between 0.76 and *** addition,the MS-NP coefficients of determination were between 0.63 and ***,it is concluded that the electrical stimulation parameters influence the behavioral outcomes ***,the PAG area may be considered a suitable candidate for forward locomotion control in the future if the area is harnessed effectively to prevent undesirable chaotic behaviors.

关键词： Periaqueductal Gray(PAG) Navigation Ratbot Animal-robot Forward locomotion Movement slope

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Interplay between temperature-dependent strengthening mechanisms and mechanical stability in high-performance austenitic stainless steels

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International Journal of Minerals,Metallurgy and Materials 2024年第10期31卷 2182-2188页

作者： mohammad Javad Sohrabi Hamed Mirzadeh Saeed Sadeghpour Milad Zolfipour Aghdam Abdol reza Geranmayeh reza Mahmudi School of Metallurgy and Materials Engineering College of EngineeringUniversity of Tehran14395-515 TehranIran Centre for Advanced Steels Research Materials and Mechanical EngineeringUniversity of Oulu90014 OuluFinland Department of Mechanical Engineering College of EngineeringUniversity of Tehran14395-515 TehranIran

The effects of deformation temperature on the transformation-induced plasticity(TRIP)-aided 304L,twinning-induced plasti-city(TWIP)-assisted 316L,and highly alloyed stable 904L austenitic stainless steels were compared for the first time to tune the mechan-ical properties,strengthening mechanisms,and strength-ductility *** this purpose,the scanning electron microscopy(SEM),electron backscattered diffraction(EBSD),X-ray diffraction(XRD),tensile testing,work-hardening analysis,and thermodynamics calcu-lations were *** induced plasticity effects led to a high temperature-dependency of work-hardening behavior in the 304L and 316L stainless *** the deformation temperature increased,the metastable 304L stainless steel showed the sequence of TRIP,TWIP,and weakening of the induced plasticity mechanism;while the disappearance of the TWIP effect in the 316L stainless steel was also ***,the solid-solution strengthening in the 904L superaustenitic stainless steel maintained the tensile properties over a wide temper-ature range,surpassing the performance of 304L and 316L stainless *** this regard,the dependency of the total elongation on the de-formation temperature was less pronounced for the 904L alloy due to the absence of additional plasticity *** results re-vealed the importance of solid-solution strengthening and the associated high friction stress for superior mechanical behavior over a wide temperature range.

关键词： austenitic stainless steels mechanical behavior stacking fault energy metastability mechanical twinning

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Numerical investigation of supercontinuum generation and optical frequency combs in Si N-based PCF with high nonlinear coefficient

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Optoelectronics Letters 2024年第3期20卷 163-170页

作者： mohammad reza Alizadeh Mahmood Seifouri Saeed Olyaee Faculty of Electrical Engineering Shahid Rajaee Teacher Training UniversityTehranIran Nano-photonics and Optoelectronics Research Laboratory(NORLab) Shahid Rajaee Teacher Training UniversityTehranIran

In this paper, a photonic crystal fiber(PCF) with a dispersion-engineered and high nonlinear coefficient has been designed for supercontinuum generation(SCG) and frequency comb generation(FCG). The proposed PCF has a Si_(3)N_(4) rod in the core. This rod provides more optical confinement in the core by increasing the refractive index of the core. This high confinement reduces the effective mode area of PCF and thus increases the nonlinear coefficient.

关键词： optical fiber nonlinear

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Multidisciplinary design optimization of a dual-spin guided vehicle

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Defence Technology（防务技术） 2024年第7期37卷 133-148页

作者： Jalal Karimi mohammad reza Rajabi Seyed Hossein Sadati Seyed Mahid Hosseini Department of Aerospace Engineering Malek Ashtar University of TechnologyTehranIran

In this research,a Multidisciplinary Design Optimization approach is proposed for the dual-spin guided flying projectile design considering external and internal parts of the body as design *** this way,a parametric formulation is *** related disciplines,including structure,aerodynamics,guidance,and control are *** total mass,maximum aerodynamic control effectiveness,minimum miss distance,maximum yield stress in all subsystems,controllability and gyroscopic stability constraints are some of objectives/constraints taken into *** problem is formulated in All-At-Ones Multidisciplinary Design Optimization approach structure and solved by Simulated Annealing and minimax *** optimal configurations are evaluated in various *** resulted optimal configurations have met all design objectives and constraints.

关键词： Flying projectile optimal design All-at-ones multidisciplinary optimization Structure discipline Guidance and control discipline Aerodynamic discipline

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Assessment of electrostatic discharge sensitivity of nitrogen-rich heterocyclic energetic compounds and their salts as high energy-density dangerous compounds:A study of structural variables

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Defence Technology（防务技术） 2024年第9期39卷 15-22页

作者： mohammad Hossein Keshavarz Sedigheh Heydari Bani reza Bakhtiari Seyyed Hesamodin Hosseini Faculty of Applied Sciences Malek Ashtar University of TechnologyIsfahan 177415875Iran

Nitrogen-rich heterocyclic energetic compounds(NRHECs)and their salts have witnessed widespread synthesis in recent *** substantial energy-density content within these compounds can lead to potentially dangerous explosive reactions when subjected to external stimuli such as electrical ***,developing a reliable model for predicting their electrostatic discharge sensitivity(ESD)becomes *** study proposes a novel and straightforward model based on the presence of specific groups(-NH_(2) or-NH-,-N=N^(+)-O^(-)and-NNO_(2),-ONO_(2) or-NO_(2))under certain conditions to assess the ESD of NRHECs and their salts,employing interpretable structural *** a comprehensive dataset comprising 54 ESD measurements of NRHECs and their salts,divided into 49/5 training/test sets,the model achieves promising *** Root Mean Square Error(RMSE),Mean Absolute Error(MAE),and Maximum Error for the training set are reported as 0.16 J,0.12 J,and 0.5 J,***,the ratios RMSE(training)/RMSE(test),MAE(training)/MAE(test),and Max Error(training)/Max Error(test)are all greater than 1.0,indicating the robust predictive capabilities of the *** presented model demonstrates its efficacy in providing a reliable assessment of ESD for the targeted NRHECs and their salts,without the need for intricate computer codes or expert involvement.

关键词： Electrostatic discharge sensitivity Heterocyclic energetic compounds containing azole compound Interpretable structural parameter Safety

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Integrating flood and earthquake resilience: a framework for assessing urban community resilience against multiple hazards

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JOURNAL OF SAFETY SCIENCE AND RESILIENCE 2024年第3期5卷 330-343页

作者： Ahmadi, Zahra Ghasemi, Mahdi Khavarian-Garmsir, Amir reza Ahmadi, mohammad Yazd Univ Fac Art & Architecture Urbanism Dept Yazd Iran Yazd Univ Fac Art & Architecture Dept Architecture Yazd Iran Univ Isfahan Fac Geog Sci & Planning Dept Geog & Urban Planning Esfahan Iran Islamic Azad Univ Dept Civil Engn Tabriz Branch Tabriz Iran

Floods and earthquakes are the most common natural disasters, causing significant damage and casualties in urban communities. Although academic research has focused on assessing cities' ability to withstand these natural disasters, there is a lack of established frameworks for evaluating resilience against multiple hazards. This research integrates the earthquake and flood resilience indicators to create a comprehensive resilience assessment framework. This study integrated seismic and flood resilience indicators and categorized them into 27 clusters. It also used the DEMATEL (Decision-Making Trial and Evaluation Laboratory) method to determine the significance of clusters and prioritize them. This research identified 13 cause clusters and 14 effect clusters of indicators for seismic and flood resilience. The 'response capacity' cluster has the most impact on seismic and flood resilience, while the 'transportation and accessibility' cluster is the most affected cluster. This article presents a framework for evaluating flood and seismic resilience and makes suggestions for future research.

关键词： Resilience Flood Earthquake Dematel Resilience assessment Multiple Hazards DEMATEL MAP

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