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Stabilization of Coupled Schrdinger and Heat Equations with Boundary Coupling

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Stabilization of Coupled Schrdinger and Heat Equations wit...

Nonlinear Stabilization Through Long Input Delay——Part Ⅰ:Forward Complete Systems

第三十届中国控制会议

作者： KRSTIC miroslav Department of Mechanical and Aerospace Engineering University of California at San Diego

＜正＞We study stability of a Schr（o|¨）dinger equation with a collocated boundary feedback compensator in the form of a heat equation with a collocated input/output *** show that the spectrum of the closed-loop system consists only of two branches along two parabolas which are asymptotically symmetric relative to the line Reλ= -Imλ（the 135°line in the second quadrant）.The asymptotic expressions of both eigenvalues and eigenfunctions are *** Riesz basis property and exponential stability of the system are then *** we show that the semigroup,generated by the system operator, is of Gevrey classδ＞ 2.A numerical computation is presented for the distributions of the spectrum of the closed-loop system.

关键词： Schrdinger equation Heat equation Boundary control Stability Spectrum Gevrey regularity

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Nonlinear Stabilization Through Long Input Delay——Part Ⅰ:...

Impulse magnetic stimulation facilitates synaptic regeneration in rats following sciatic nerve injury

Joint 48th IEEE Conference on Decision and Control and 28th Chinese Control Conference

作者： miroslav Krstic Department of Mechanical and Aerospace Engineering University of California

We present an approach for compensating input delay of arbitrary length in nonlinear control *** approach, which due to the infinite dimensionality of the actuator dynamics and due to the nonlinear character of the plant results in a nonlinear feedback operator, is essentially a nonlinear version of the Smith Predictor and its various predictor-based modifications for linear *** stabilization in the presence of arbitrarily long delay is achieved for all nonlinear plants that are globally stabilizable in the absence of delay and that satisfy the property of forward completeness（which is satisfied by most mechanical systems, electromechanical systems, vehicles, and other physical systems）.

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Neural Regeneration Research 2012年第17期7卷 1299-1303页

作者： Sergey A.Zhivolupov miroslav M.Odinak Nariman A.Rashidov Ludmila S.Onischenko Igor N.Samartsev Anton A.Jurin Department of Neurology Military-Medical AcademySaint-Petersburg194044Lesnoy prospect 2Russian Federation

The current studies describing magnetic stimulation for treatment of nervous system diseases mainly focus on transcranial magnetic stimulation and rarely focus on spinal cord magnetic stimulation. Spinal cord magnetic stimulation has been confirmed to promote neural plasticity after injuries of spinal cord, brain and peripheral nerve. To evaluate the effects of impulse magnetic stimulation of the spinal cord on peripheral nerve regneration, we compressed a 3 mm segment located in the middle third of the hip using a sterilized artery forceps to induce ischemia. Then, all animals underwent impulse magnetic stimulation of the lumbar portion of spinal crod and spinal nerve roots daily for 1 month. Electron microscopy results showed that in and below the injuryed segment, the inflammation and demyelination of neural tissue were alleviated, apoptotic cells were reduced, and injured Schwann cells and myelin fibers were repaired. These findings suggest that high-frequency impulse magnetic stimulation of spinal cord and corresponding spinal nerve roots promotes synaptic regeneration following sciatic nerve injury.

关键词： impulse magnetic stimulation experimental neuropathy sciatic nerve lesion neuroplasticity neuralregeneration

Longitudinal molecular characterization of endoscopic specimens from colorectal lesions

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World Journal of Gastroenterology 2016年第20期22卷 4936-4945页

作者： Petra Minarikova Lucie Benesova Tereza Halkova Barbora Belsanova Stepan Suchanek Jiri Cyrany Inna Tuckova Jan Bures miroslav Zavoral Marek Minarik Department of Internal Medicine 1st Faculty of Medicine of Charles University and Military University Hospital Genomac Research Institute Centre for Applied Genomics of Solid Tumors 2nd Department of Internal Medicine - Gastroenterology Charles University Faculty of Medicine at Hradec Kralove University Teaching Hospital

AIM: To compare molecular profiles of proximal colon, distal colon and rectum in large adenomas, early and late carcinomas. To assess feasibility of testing directed at molecular markers from this study in routine clinical practice. METHODS: A prospective 3-year study has resulted in the acquisition of samples from 159 large adenomas and 138 carcinomas along with associated clinical parameters including localization, grade and histological type for adenomas and localization and stage for carcinomas. A complex molecular phenotyping has been performed using multiplex ligation-dependent probe amplification technique for the evaluation of Cp G-islandmethylator phenotype(CIMP), PCR fragment analysis for detection of microsatellite instability and denaturing capillary electrophoresis for sensitive detection of somatic mutations in KRAS, BRAF, TP53 and APC ***: Molecular types according to previously introduced Jass classification have been evaluated for large adenomas and early and late carcinomas. An increase in CIMP+ type, eventually accompanied with KRAS mutations, was notable between large adenomas and early carcinomas. As expected, the longitudinal observations revealed a correlation of the CIMP+/BRAF + type with proximal location. CONCLUSION: Prospective molecular classification of tissue specimens is feasible in routine endoscopy practice. Increased frequency of some molecular types corresponds to the developmental stages of colorectal tumors. As expected, a clear distinction is notable for tumors located in proximal colon supposedly arising from the serrated(methylation) pathway.

关键词： Colorectal cancer Cp G-island methylator phenotype DNA Microsatellite instability BRAF

Study on Negative Impact of Harmonic Components on Sensitive Electric Equipment

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Journal of Energy and Power Engineering 2013年第4期7卷 733-739页

作者： miroslav Dubovsky Alena Otcenasova Michal Pokorny The Central Slovak Distribution Company Inc. (SSE-Distribution a.s.) Zilina 01047 Slovakia Department of Power Electrical Systems Faculty of Electrical Engineering University of Zilina Zilina 010 26 Slovakia

Distribution systems operators are often confronted with declined power quality, which can cause substantial economical losses. The problem analyzed in paper concerns thyristor controlled direct current motor used for ski-lift in ski resort as a source of disturbances with negative impact on sensitive electric equipment, which is then unable to operate correctly. To solve mentioned problems, series of measurements of voltage quality parameters were carried out according to the respective valid standards. Crucial power quality parameters necessary for parallel power active filter design were then analyzed. Power active filter compensates power factor and filters characteristic current harmonics. After power active filter was put into operation, power quality problems were eliminated. Payback period is estimated up to four years.

关键词： Power quality higher harmonics total harmonic distortion power factor power active filter sensitive electric equipment.

Basal cell carcinoma stem cells exhibit osteogenic and chondrogenic differentiation potential

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BIOCELL 2021年第6期45卷 1543-1550页

作者： MAJA MILOSEVIC MILOS LAZAREVIC BOSKO TOLJIC MILAN PETROVIC miroslav VUKADINOVIC ZORAN JEZDIC BOBAN ANICIC DRAGO JELOVAC SVETLANA JOVANOVIC JELENA MILASIN Department of Human Genetics School of Dental MedicineUniversity of BelgradeBelgrade11000Serbia Clinic for Maxillofacial Surgery School of Dental MedicineUniversity of BelgradeBelgrade11000Serbia Department of Public Health School of Dental MedicineUniversity of BelgradeBelgrade11000Serbia

Specific cell subpopulations identified as cancer stem cells(CSCs)can be found in basal cell carcinoma(BCC).Generally,CSCs have a marked trans-differentiation potential that could potentially be used in differentiation ***,there are no studies regarding BCC CSCs *** aim of the study was to analyze the characteristic of CSCs of BCC with emphasis on their differentiation potential upon specific *** staining and cell morphology were used for differentiation confirmation,along with the expression analysis of osteogenic(ALP,BSP,Runx2,OCN,BMP2),chondrogenic(COL1 and COL2A1),adipogenic(PPAR-γ)and neurogenic(Nestin and MAP2)*** CSCs differentiated into osteogenic and chondrogenic lineages,as judged by staining and high expression of specific markers(from 2-to 92-fold higher upon induction).Concomitantly with differentiation,the levels of cancer stem cell markers decreased in the ***-differentiation and neuro-differentiation were *** conclusion,BCC CSCs exhibit the capacity to trans-differentiate,a characteristic that may potentially be useful in the development of new strategies for the treatment of aggressive BCCs.

关键词： Basal cell carcinoma Cancer stem cells Differentiation potential Osteo-differentiation Chondro-differentiation

A Wideband Circularly Polarized Jeans-Based Antenna at 2.45 GHz

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Open Journal of Antennas and Propagation 2020年第1期8卷 1-18页

作者： miroslav Joler Anamaria Kolonic Maja Boljkovac Department of Computer Engineering Faculty of EngineeringUniversity of RijekaRijekaCroatia

Development of textile antennas is an important segment towards the goal of creating smart clothing. In this paper, we report on a jeans-based circularly polarized textile antenna designed for the E-band (around 2.45 GHz). We present three variations of the design and the respective results. The antenna comprises a multi-layer jeans-fabric as the substrate, a conductive fabric as the patch, which is concealed with another layer of jeans, and the ground plane is formed by either a cooper foil or another conductive fabric. A multi-layer structure was chosen to provide a wider bandwidth and better efficiency, whereas the upper surface of the antenna was covered by one more layer of jeans to both make the antenna less conspicuous, when worn on the arm, and protect the patch and substrate from mechanical damages and moisture. All three variants are characterized by a good realized gain of about 3 dB, a wide beam width and a wide bandwidth of 21% or better, around 2.45 GHz, having the radiation efficiency around 36%, and front-to-back ratio of 5 dB or better, with the ground plane being just slightly larger than the patch.

关键词： Textile Antenna Circular Polarization Jeans-Based Antenna Probe Feed

Minimal Requests on High-Fidelity Audio Recording and Reproduction

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Computer Technology and Application 2011年第9期2卷 705-711页

作者： Tomislav Jarmie Vesna Dusak miroslav Baea Varazdin County Franciseani Square 7 Varazdin 42000 Croatia Faculty of Organization and Informatics University of Zagreb Pavlinska 2 Varazdin 42000 Croatia

Sound recording quality, whether digital or analogue, presupposes true-to-life recording of the original audio signal. Contemporary audio media do not meet the requirements of high-fidelity recording since they do not insufficiently utilize the bandwidth for D/A conversion and sufficient word length. This paper deals with the values of these parameters in high-fidelity recording. The paper presents the results of a research into characteristics of faithful and high-fidelity audio recording considering the frequency range, signal-to-noise ratio and dynamic range.

关键词： High-fidelity audio quality audio recording and reproduction Nyquist theorem

Evaluation of the combined activity of benzimidazole arylhydrazones as new anti-Parkinsonian agents:monoamine oxidase-B inhibition,neuroprotection and oxidative stress modulation

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Neural Regeneration Research 2021年第11期16卷 2299-2309页

作者： Neda Anastassova Denitsa Aluani Anton Kostadinov miroslav Rangelov Nadezhda Todorova Nadya Hristova-Avakumova Maria Argirova Nikolay Lumov Magdalena Kondeva-Burdina Virginia Tzankova Denitsa Yancheva Institute of Organic Chemistry with Centre of Phytochemistry Bulgarian Academy of SciencesSofiaBulgaria Department of Pharmacology Pharmacotherapy and ToxicologyFaculty of PharmacyMedical University of SofiaSofiaBulgaria Institute of Biodiversity and Ecosystem Research Bulgarian Academy of SciencesSofiaBulgaria Department of Medical Physics and Biophysics Faculty of MedicineMedical University of SofiaSofiaBulgaria

Neuroprotective drugs and selective monoamine oxidase inhibitors can slow down the progression and improve symptoms of Parkinson’s disease(PD).Since there is an implication of oxidative stress in the pathophysiological mechanisms of the disease,the compounds possessing an ability to reduce the oxidative stress are prime candidates for *** our current study is focused on the development of new multi-target PD drugs capable of inhibiting the activity of monoamine oxidase-B while exerting neuroprotective and antioxidant properties.A small series of benzimidazole derivatives containing hydroxy and methoxy arylhydrazone fragments has been synthesized and the neurotoxicity of the compounds has been evaluated in vitro on neuroblastoma SH-SY5Y cells and on isolated rat brain synaptosomes by measuring the cell viability and the levels of reduced glutathione and a good safety profile has been *** 2-hydroxy-4-methoxy substituted arylhydrazone 7 was the least toxic on neuronal SH-SY5Y cells and showed the lowest neurotoxicity in rat brain *** neuroprotective properties of the test compounds were further assessed using two models:H2O2-induced oxidative stress on SH-SY5Y cells and 6-hydroxydopamine-induced neurotoxicity in rat brain *** 7 showed more pronounced neuroprotective activity on SH-SY5Y cells,compared to the referent melatonin and *** also preserved the synaptosomal viability and the reduced glutathione levels;the effects were stronger than those of rasagiline and comparable to *** the tested compounds were capable to inhibit human monoamine oxidase-B enzyme to a significant extent,however,compound 7 exerted the most prominent inhibitory activity,similar to selegiline and *** carried out molecular docking studies revealed that the activity is related to the appropriate molecular structure enabling the ligand to enter deeper in the narrow and highly lipophylic active site pocket of th

关键词： antioxidants benzimidazoles density functional theory hydr