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Is it better to use two elastographic methods for liver fibrosis assessment?

World Journal of Gastroenterology 2011年第33期17卷 3824-3829页

作者： Ioan Sporea Roxana Sirli Alina Popescu Simona Bota Radu Badea Monica Lupsor mircea focsa Mirela Danila Department of Gastroenterology and Hepatology University of Medicine and Pharmacy Timisoara10 Iosif Bulbuca Bv.300736 TimisoaraRomania Department of Medical Imaging 3rd Medical ClinicUniversity of Medicine and PharmacyClujNapoca2123 Croitorilor str.400162 ClujNapocaRomania Department of Biophysics and Medical Informatics University of Medicine and Pharmacy Timisoara14 Tudor Vladimirescu str.300173 TimisoaraRomania

AIM:To find out if by combining 2 ultrasound based elastographic methods:acoustic radiation force impulse(ARFI)elastography and transient elastography(TE),we can improve the prediction of fibrosis in patients with chronic hepatitis ***:Our study included 197 patients with chronic hepatitis *** each patient,we performed,in the same session,liver stiffness(LS)measurements by means of TE and ARFI,respectively,and liver biopsy(LB),assessed according to the Metavir score.10 LS measurements were performed both by TE and ARFI;median values were calculated and expressed in kilopascals(kPa)and meters/second(m/s),*** TE and ARFI measurements with IQR<30%andSR≥60%were considered ***:On LB 13(6.6%)patients had F0,32(16.2%) had F1,52(26.4%)had F2,47(23.9%)had F3,and 53(26.9%)had F4.A direct,strong correlation was found between TE measurements and fibrosis(r=0.741),between ARFI and fibrosis(r=0.730)and also between TE and ARFI(r=0.675).For predicting significant fibrosis(F≥2),for a cutoff of 6.7 kPa,TE had 77.5% sensitivity(Se)and 86.5%specificity(Sp)[area under the receiver operating characteristic curve(AUROC)0.87] and for a cutoff of 1.2 m/s,ARFI had 76.9%Se and 86.7%Sp(AUROC 0.84).For predicting cirrhosis(F=4),for a cutoff of 12.2 kPa,TE had 96.2%Se and 89.6% Sp(AUROC 0.97)and for a cutoff of 1.8 m/s,ARFI had 90.4%Se and 85.6%Sp(AUROC 0.91).When both elastographic methods were taken into consideration,for predicting significant fibrosis(F≥2),(TE≥6.7 kPa and ARFI≥1.2 m/s)we obtained 60.5%Se,93.3% Sp,96.8%positive predictive value(PPV),41.4%negative predictive value(NPV)and 68%accuracy,while for predicting cirrhosis(TE≥12.2 kPa and ARFI≥1.8 m/s) we obtained 84.9%Se,94.4%Sp,84.9%PPV,94.4% NPV and 91.8%***:TE used in combination with ARFI is highly specific for predicting significant fibrosis;therefore when the two methods are concordant,liver biopsy can be avoided.

关键词：肝纤维化 c方法评估丙型肝炎预测性 kPa 特征曲线肝硬化

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Corrosion Investigation by Scanning Electrochemical Microscopy of AISI 446 and Ti-Coated AISI 446 Ferritic Stainless Steel as Potential Material for Bipolar Plate in PEMWE

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Acta Metallurgica Sinica(English Letters) 2024年第4期37卷 607-619页

作者： Andrea Kellenberger Nicolae Vaszilcsin mircea Laurentiu Dan Ion Mitelea Alexandru Adrian Geana Sigrid Lædre Corneliu M.Craciunescu Faculty of Industrial Chemistry and Environmental Engineering Politehnica University TimisoaraPiata Victoriei 2300006TimisoaraRomania Faculty of Mechanical Engineering Politehnica University TimisoaraPiata Victoriei 2300006TimisoaraRomania SINTEF Industry 7465TrondheimNorway

The components of proton exchange membrane water electrolysers frequently experience corrosion issues, especially at high anodic polarization, that restrict the use of more affordable alternatives to titanium. Here, we investigate localized corrosion processes of bare and Ti-coated AISI 446 ferritic stainless steel under anodic polarization by scanning electrochemical microscopy (SECM) in sodium sulphate and potassium chloride solutions. SECM approach curves and area scans measured at open-circuit potential (OCP) of the samples in the feedback mode using a redox mediator evidence a negative feedback effect caused by the surface passive film. For the anodic polarization of the sample, the substrate generation-tip collection mode enables to observe local generation of iron (II) ions, as well as formation of molecular oxygen. For the uncoated AISI 446 sample, localized corrosion is detected in sodium sulphate solution simultaneously with oxygen formation at anodic potentials of 1.0 V vs. Ag/AgCl, whereas significant pitting corrosion is observed even at 0.2 V vs. Ag/AgCl in potassium chloride solution. The Ti-coated AISI 446 sample reveals enhanced corrosion resistance in both test solutions, without any evidence of iron (II) ions generation at anodic potentials of 1.2 V vs. Ag/AgCl, where only oxygen formation is observed.

关键词： Ferritic stainless steel Corrosion Ti coating Scanning electrochemical microscopy(SECM) Magnetron sputtering Proton exchange membrane water electrolysis(PEMWE)

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A GENERALIZED PENALTY METHOD FOR DIFFERENTIAL VARIATIONAL-HEMIVARIATIONAL INEQUALITIES

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Acta Mathematica Scientia 2022年第1期42卷 247-264页

作者：卢亮李丽洁 mircea SOFONEA Guangxi Key Laboratory of Cross-border E-commerce Intelligent Information Processing Guangxi University of Finance and EconomicsNanning 530003China Guangxi Colleges and Universities Key Laboratory of Complex System Optimization and Big Data Processing Yulin Normal UniversityYulin 537000China Laboratoire de Mathématiques et Physique Universitéde Perpignan Via Domitia52 Avenue Paul Alduy66860 PerpignanFrance

We consider a differential variational-hemivariational inequality with constraints,in the framework of reflexive Banach *** existence of a unique mild solution of the inequality,together with its stability,was proved in[1].Here,we complete these results with existence,uniqueness and convergence results for an associated penalty-type *** this end,we construct a sequence of perturbed differential variational-hemivariational inequalities governed by perturbed sets of constraints and penalty *** prove the unique solvability of each perturbed inequality as well as the convergence of its solution to the solution of the original ***,we consider a mathematical model which describes the equilibrium of a viscoelastic rod in unilateral *** weak formulation of the model is in a form of a differential variational-hemivariational inequality in which the unknowns are the displacement field and the history of the *** apply our abstract penalty method in the study of this inequality and provide the corresponding mechanical interpretations.

关键词： differential variational-hemivariational inequality generalized penalty method Mosco convergence viscoelastic rod unilateral constraint

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Alternative principles and minimax inequalities in G-convex spaces

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Applied Mathematics and Mechanics(English Edition) 2008年第5期29卷 665-672页

作者： mircea Balaj Department of Mathematics University of Oradea410087 OradeaRomania

Using a fixed point theorem by Kuo, Jeng and Huang, we obtain in G-convex spaces a very general intersection theorem concerning the values of three maps. From this result we derive successively alternative theorems co... 详细信息

关键词： G-convex space strict KKM property fixed point theorem maximal element alternative theorem minimax inequality

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Adapted Metrics and Webster Curvature in Finslerian 2-Dimensional Geometry

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Chinese Annals of Mathematics,Series B 2016年第3期37卷 419-426页

作者： mircea CRASMAREANU Feculty of Mathematics University A1. I. Cuza Iasi 700506 Romania.

The Webster scalar curvature is computed for the sphere bundle T_1S of a Finsler surface(S, F) subject to the Chern-Hamilton notion of adapted metrics. As an application,it is derived that in this setting(T_1S, g Sasaki) is a Sasakian manifold homothetic with a generalized Berger sphere, and that a natural Cartan structure is arising from the horizontal 1-forms and the author associates a non-Einstein pseudo-Hermitian structure. Also, one studies when the Sasaki type metric of T_1S is generally adapted to the natural co-frame provided by the Finsler structure.

关键词：标量曲率度量和韦伯几何二维 Cartan 埃尔米特爱因斯坦

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Vulnerability of groundwater resources under climate change in the Pannonian basin

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Geo-Spatial Information Science 2019年第4期22卷 345-358,I0010页

作者： Mărgărit-mircea Nistor National Institute for Economic Research“Costin C.Kiritescu”of the Romanian Academy/Department of Mountain Economy(CE-MONT) Vatra DorneiRomania Department of Hydrogeology Earthresearch CompanyCluj-NapocaRomania

The impact of climate change on groundwater vulnerability has been assessed in the Pannonian basin over 1961–***-resolution climatemodels,aquifers composition,land cover,and digital elevation model were the main factors which served to perform the spatial analysis using Geographical Information *** analysis reported here is focused on the long-term period,including three temporal time sets:the past period of 1961–1990(1990s),the present period of 2011–2040(2020s),and the future period of 2041–2070(2050s).During the 1990s,the high and very high areas of groundwater vulnerability were identified in all the central,western,eastern,southeastern,and northern sides of the Pannonian *** these areas,the water availability is lower and the pollution load index is high,due to the agricultural *** low and very low vulnerability classwas depicted in the South-West part of the basin and in few locations from the peripheral areas,mainly in the North and *** medium groundwater vulnerability spreads over the Pannonian basin,but it ismore concentrated in the central,South,and *** most affected territory is Hungary,while the territories of Slovenia,Croatia,and Bosnia and Herzegovina are less *** the present and future periods,the very high groundwater vulnerability increased in areas by 0.74%and 0.87%,*** low class area decreased between the 1990s and the 2020s by 2.33%and it is expected to decrease up to 2.97%in the *** on this analysis and the groundwater vulnerabilitymaps,the Pannonian basin appears more vulnerable to climate change in the present and *** findings demonstrate that the aquifers from Pannonian basin experience high negative effect under climate *** addition,the land cover contributes to this negative status of groundwater *** original maps of groundwater vulnerability represent an instrument for water management planning and for research.

关键词： Vulnerability aquifers spatial analysis climatic models pollution load index infiltration index water availability

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Statistical Structures on Metric Path Spaces

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Chinese Annals of Mathematics,Series B 2012年第6期33卷 889-902页

作者： mircea CRASMAREANU Cristina-Elena HRET CANU Faculty of Mathematics Alexandru Ioan Cuza University Faculty of Food Engineering Stefan Cel Mare University

The authors extend the notion of statistical structure from Riemannian geometry to the general framework of path spaces endowed with a nonlinear connection and a generalized *** particular cases of statistical data are *** existence and uniqueness of a nonlinear connection corresponding to these classes is *** Koszul tensors are introduced in accordance with the Riemannian *** applications,the authors treat the Finslerian (α,β)-metrics and the Beil metrics used in relativity and field theories while the support Riemannian metric is the Fisher-Rao metric of a statistical model.

关键词：统计结构空间结构路径广义度量空间 Koszul模公制黎曼度量统计数据

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Para-CR Structures of Codimension 2 on Tangent Bundles in Riemann–Finsler Geometry

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Acta Mathematica Sinica,English Series 2014年第11期30卷 1877-1884页

作者： mircea CRASMAREANU Laurian-Ioan PISCORAN Faculty of Mathematics University "Al.I.Cuza" of Iasi700506Romania Department of Mathematics and Computer Science North Univ.Center of Baia MareTechnical Univ.of Cluj Napoca430122Romania

We determine a 2-codimensional para-CR structure on the slit tangent bundle T0 M of a Finsler manifold（M,F） by imposing a condition regarding the almost paracomplex structure P associated to F when restricted to the structural distribution of a framed *** condition is satisfied when（M,F） is of scalar flag curvature（particularly constant） or if the Riemannian manifold（M,g） is of constant curvature.

关键词： Para-CR structure metric framed para-f-structure Finsler geometry scalar flag curvature space form

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Electrochemical studies on cerium(Ⅲ) in molten fluoride mixtures

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Journal of Rare Earths 2010年第3期28卷 428-434页

作者： VIRGIL CONSTANTIN ANA-MARIA POPESCU mircea OLTEANU Romanian Academy Institute of Physical Chemistry "Ilie Murgulescu"Department of Molten Salts Splaiul Independentei 202Bucharest-Romania

This study aims to determine the principal electrochemical characteristics of the electrodeposition of cerium metal from molten fluoride *** cathodic process of Ce3+ ions in LiF-NaF and LiF-NaF-CaF2 molten salts was studied using electrochemical techniques as steady state and cyclic voltammetry *** decomposition potential(Ed) and the overvoltage(η) were determined for NaCeF4 using current-potential curves under galvanostatic *** Ed was found to be 2.025 V in LiF-NaF and 2.045 V in...

关键词： cerium molten salts lanthanides NaCeF4 electrolysis cyclic voltammetry

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Robot-assisted surgery for gastric cancer

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World Journal of Gastrointestinal Oncology 2016年第1期8卷 8-17页

作者： livia procopiuc stefan tudor mircea manuc mircea diculescu catalin vasilescu "carol davila"university of medicine and pharmacy 020022 BucharestRomania department of general surgery and liver transplantation fundeni clinical institute022238 BucharestRomania department of gastroen-terology and hepatology fundeni clinical institute022238 BucharestRomania

Minimally invasive surgery for gastric cancer is a rela-tively new research field, with convincing results mostly stemming from Asian countries. The use of the robotic surgery platform, thus far assessed as a safe procedure, which is also easier to learn, sets the background for a wider spread of minimally invasive technique in the treatment of gastric cancer. This review will cover the literature published so far, analyzing the pros and cons of robotic surgery and highlighting the remaining study questions.

关键词： Gastric cancer survival Robotic surgery Gastric cancer surgery Lymphadenectomy Minimallyinvasive surgery

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