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An Improvement of Pedestrian Detection Method with Multiple Resolutions

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Journal of Computer and Communications 2017年第9期5卷 102-116页

作者： Guodong Zhang Peilin Jiang Kazuyuki Matsumoto minoru yoshida Kenji Kita Faculy and School of Engineering Tokushima University Tokushima Japan Xi’an Jiaotong University Xian China

In object detection, detecting an object with 100 pixels is substantially different from detecting an object with 10 pixels. Many object detection algorithms assume that the pedestrian scale is fixed during detection, such as the DPM detector. However, detectors often give rise to different detection effects under the circumstance of different scales. If a detector is used to perform pedestrian detection in different scales, the accuracy of pedestrian detection could be improved. A multi-resolution DPM pedestrian detection algorithm is proposed in this paper. During the stage of model training, a resolution factor is added to a set of hidden variables of a latent SVM model. Then, in the stage of detection, a standard DPM model is used for the high resolution objects and a rigid template is adopted in case of the low resolution objects. In our experiments, we find that in case of low resolution objects the detection accuracy of a standard DPM model is lower than that of a rigid template. In Caltech, the omission ratio of a multi-resolution DPM detector is 52% with 1 false positive per image (1FPPI);and the omission ratio rises to 59% (1FPPI) as far as a standard DPM detector is concerned. In the large-scale sample set of Caltech, the omission ratios given by the multi-resolution and the standard DPM detectors are 18% (1FPPI) and 26% (1FPPI), respectively.

关键词： Deformable Part Model Pedestrian Detection Multi-Resolution Latent SVM

Compression of 40-,20-,and 10GHz Optical Pulses from Mode-locked Er3+-doped Fiber Lasers by External Chirp Compensation

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Compression of 40-,20-,and 10GHz Optical Pulses from Mode-lo...

Analysis on the mechanism of the nucleocytoplasmic movement of CRM1, a leucine-rich NES receptor.

亚太地区通信会议暨光电子通信会议

作者： Shigeyuki Seikai Ikuo Yamashita Kazuhiro Shimoura minoru yoshida Kansai Electric Power Co.Inc. Kansai Electric Power Co.Inc. Kansai Electric Power Co.Inc. Mitsubishi Cable Industries LTD.3-11-20 Nakoji Amagasaki Hyogo 661-0974 JAPAN

Optical pulses with 3-ps,3.4-ps,and 3.8-pswidths at frequencies of 40,20,and 10GHz,respectively are obtained by externally attachinga conventional single-mode fiber to the mode-locked fiber laser to compensate for the...

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Analysis on the mechanism of the nucleocytoplasmic movement ...

High exposure of Chinese mercury mine workers to elemental mercury vapor and their increased hair methylmercury levels: A preliminary report

Third Congress of the Asian-Pacific Organization for Cell Biology

作者： Makoto Fukuda Shiro Asano Nobuaki Kudo minoru yoshida Eisuke Nishida Dept. Biophys. Grad. Sch. of ScienceKyoto Univ.Sakyo-kuKyoto 606Japan Dept. of Biotec. Grad. Sch. of Agriculture and Life ScienceUniv. of TokyoBunkyo-kuTokyo 113Japan

The discovery of nuclear export signals (NESs) in a number of proteins revealed the signal-dependent transport of proteins from the nucleus to the cytoplasm. It has recently been revealed

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Chinese Journal Of Geochemistry 2006年第B8期25卷 42-43页

作者： Mineshi Sakamoto Xinbin FENG Ping LI Guangle QIU Hongmei JIANG minoru yoshida Toyoto Iwata Xiaojie LIU Katsuyuki Murata National Institute for Minamata Disease Minamata 867-0008 Japan State Key Laboratory of Environmental Geochemistry Institute of Geochemistry Chinese Academy of Sciences Guiyang 550002 China Faculty of Human Health Science Hachinohe University Hachinohe 031-8566 Japan Department of Environmental Health Sciences Akita University School of Medicine

PNAS:科学家首次鉴别出让寨卡病毒如此致命的关键蛋白

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现代生物医学进展 2017年第3期17卷 I0001-I0002页

作者： Ge Li[a] Melissa Poulsen[a] Csaba Fenyvuesvolgyi[a] Yoko Yashiroda[b] minoru yoshida[b] J. Marc Simard[a],[c] Robert C. Gallo[d],[e],[f], Richard Y. Zhao[a],[d],[e], [a]Department of Pathology University of Maryland School of Medicine Baltimore MD 21201 [b]RIKEN Center for Sustainable Resource Science Wako Saitama 351-0198 Japan [c]Department of Neurosurgery University of Maryland School of Medicine Baltimore MD 21201 [d]Department of Microbiology and Immunology University of Maryland School of Medicine Baltimore MD 21201 [e]Institute of Human Virology University of Maryland School of Medicine Baltimore MD 21201 [f]Department of Medicine University of Maryland School of Medicine Baltimore MD 21201

当寨卡病毒横空出世时科学家们对其知之甚少。在过去一年里研究者们通过深入研究来阐明寨卡病毒为何会引发一系列危险的健康问题。包括新生儿缺陷等，比如小头畸型和神经性问题（格--巴二氏综合征等）。但研究者们并不知道寨卡病毒哪种... 详细信息

当寨卡病毒横空出世时科学家们对其知之甚少。在过去一年里研究者们通过深入研究来阐明寨卡病毒为何会引发一系列危险的健康问题。包括新生儿缺陷等，比如小头畸型和神经性问题（格--巴二氏综合征等）。但研究者们并不知道寨卡病毒哪种蛋白会让其变得具有杀伤性。当然他们也不清楚这些蛋白质的作用机理是什么。

关键词：蛋白质科学家病毒出让鉴别健康问题新生儿综合征

Insulin-like growth factor-I receptor in proliferation and motility of pancreatic cancer

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World Journal of Gastroenterology 2010年第15期16卷 1854-1858页

作者： minoru Tomizawa Fuminobu Shinozaki Takao Sugiyama Shigenori Yamamoto Makoto Sueishi Takanobu yoshida Department of Gastroenterology National Hospital Organization Shimoshizu Hospital Department of Radiology National Hospital Organization Shimoshizu Hospital Department of Rheu-matology National Hospital Organization Shimoshizu Hospital Department of Pediatrics National Hospital Organization Shimoshizu Hospital Department of Internal Medicine National Hospital Organization Shimoshizu Hospital

AIM:To develop a molecular therapy for pancreatic cancer, the insulin-like growth factor-I (IGF-I) signaling pathway was ***: Pancreatic cancer cell lines (MIA-Paca2, NOR-P1, PANC-1, PK-45H, PK-1, PK-59 and KP-4) were cultured in media with 10 mL/L fetal bovine serum. Western blotting analysis was performed to clarify the expression of IGF-I receptor (IGF-IR). Picropodophyllin (PPP), a specific inhibitor of IGF-IR, LY294002, a specific inhibitor of phosphatidylinositol3 kinase (PI3K), and PD98059, a specific inhibitor of mitogen-activated protein kinase, were added to the media. After 72 h, a 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium inner salt (MTS) assay was performed to analyze cell proliferation. A wound assay was performed to analyze cell motility with hematoxylin and eosin (HE) staining 48 h after addition of each inhibitor. RESULTS: All cell lines clearly expressed not only IGF-IR but also phosphorylated IGF-IR. PPP significantly suppressed proliferation of MIA-Paca2, NOR-P1, PANC-1, PK-45H, PK-1, PK-59 and KP-4 cells to 36.9% ± 2.4% (mean ± SD), 30.9% ± 5.5%, 23.8% ± 3.9%, 37.1% ± 5.3%, 10.4% ± 4.5%, 52.5% ± 4.5% and 22.6% ± 0.4%, at 2 μmol/L, respectively (P < 0.05). LY294002 significantly suppressed proliferation of MIA-Paca2, NOR-P1, PANC-1, PK-45H, PK-1, PK-59 and KP-4 cells to 44.4% ± 7.6%, 32.9% ± 8.2%, 53.9% ± 8.0%, 52.8% ± 4.0%, 32.3% ± 4.2%, 51.8% ± 4.5%, and 30.6% ± 9.4%, at 50 μmol/L, respectively (P < 0.05). PD98059 did not significantly suppress cell proliferation. PPP at 2 μmol/L suppressed motility of MIA-Paca2, NOR-P1, PANC-1, PK-45H, PK-1, PK-59 and KP-4 cells to 3.0% ± 0.2%, 0%, 0%, 2.0% ± 0.1%, 5.0% ± 0.2%, 3.0% ± 0.1%, and 5.0% ± 0.2%, respectively (P < 0.05). LY294002 at 50 μmol/L suppressed motility of MIA-Paca2, NOR-P1, PANC-1, PK-45H, PK-1, PK-59 and KP-4 to 3.0% ± 0.2%, 0%, 3.0% ± 0.2%, 0%, 0%, 0% and 3% ± 0.1%, respectively (P < 0.05). PD980509 at 20 μmol/L did not suppress

关键词： Insulin-like growth factor-I receptor Phosphatidylinositol 3 kinase Pancreatic neoplasms

Reconstruction of Chest Wall after Extensive Chest Wall Necrosis Caused by Transcatheter Arterial Embolization of Bilateral Internal Mammary Arteries Injured by Cardiopulmonary Resuscitation—A Case Report

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Modern Plastic Surgery 2019年第2期9卷 33-43页

作者： Ayako Kamitomo minoru Hayashi Ryohei Tokunaka Yuki yoshida Sayo Tatsuta Yoshie Sasaki Department of Plastic Reconstructive and Aesthetic Surgery Japan Red Cross Maebashi Hospital Maebashi-shi Japan

Transcatheter Arterial Embolization (TAE) is known to be effective for controlling severe hemorrhage caused by iatrogenic or blunt trauma. Out of more than 100 cases of TAE performed in our hospital, we have treated some cases of skin or muscle necrosis that resulted from embolization of the main arteries. In this study, we report the case of a patient with significant chest wall necrosis after TAE of the bilateral internal mammary arteries (IMAs). A 66-year-old male was transported to our hospital for loss of consciousness while playing golf. Cardiopulmonary resuscitation (CPR) was performed for cardiac arrest, which resulted in several rib fractures and mediastinal hematoma due to bilateral mammary artery injuries. Immediate TAE embolization was performed because of continuous hemorrhage. He was referred to our department 16 days after embolization due to the presentation of chest wall necrosis. Heart, lungs and diaphragm were exposed after surgical debridement under systemic anesthesia. We performed several operations to reconstruct the anterior chest wall. His spontaneous respiration returned, and is now controlled with a tracheostomy tube. Complete epithelialization was achieved, and he was transferred to another hospital for further rehabilitation. To the best of our knowledge, this is the first report of chest wall necrosis resulting from TAE of IMAs. Arterial embolization can cause widespread necrosis of bone, muscle and skin. Although treatment required an extended period, we managed to reconstruct the chest wall with multidisciplinary strategies.

关键词： Transcatheter Arterial Embolization Chest Wall Reconstruction Internal Mammary Arteries Negative Pressure Wound Therapy Cardiopulmonary Resuscitation

贵州省务川地区土法炼汞工人汞蒸汽暴露调查及健康影响评价

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生态毒理学报 2006年第1期1卷 30-34页

作者：李平冯新斌仇广乐蒋红梅李仲根付学吾白薇扬 MinishiSakamoto 刘晓洁 minoruyoshida ToyotoIwata 王定勇张成中国科学院地球化学研究所环境地球化学国家重点实验室 MinistryoftheEnvironmentNationalInstituteforMinamataDisease DepartmentofBiochemistry DivisionofChemistry St.MariannaUniversitySchoolofMedicine216-8511SugaoMiyamae-kuKawasakiJapan EnvironmentalHealthSciences DepartmentofSocialMedicine AkitaUniversitySchoolofMedicine010-8543AkitaHondoJapan 西南农业大学资源环境学院重庆400716

为探讨土法炼汞过程中汞蒸汽暴露对炼汞工人健康的影响,测定了贵州省务川土法炼汞区和对照区(贵州省长顺县)人群的尿汞、尿常规参数(pH、葡萄糖、尿胆红素原、潜血、尿蛋白)、尿肌酐和尿β2微球蛋白含量,并对两地区人群进行了详细的健... 详细信息

为探讨土法炼汞过程中汞蒸汽暴露对炼汞工人健康的影响,测定了贵州省务川土法炼汞区和对照区(贵州省长顺县)人群的尿汞、尿常规参数(pH、葡萄糖、尿胆红素原、潜血、尿蛋白)、尿肌酐和尿β2微球蛋白含量,并对两地区人群进行了详细的健康检查．测定结果显示,土法炼汞区人群尿汞和尿β2微球蛋白的平均含量分别高达779μg·g-1 Cr 和208．5μg·g-1 Cr,远远高于对照区人群的尿汞1．24μg·g-1 Cr和尿β2微球蛋白75．4μg·g-1 Cr．分析表明,务川地区土法炼汞人群遭受了较严重的汞蒸汽暴露,部分暴露人群已经表现出轻度慢性汞中毒的症状,其肾脏已经遭受到一定程度的损伤．

关键词：汞蒸汽暴露健康影响评价土法炼汞务川地区贵州

Preparation and Evaluation of Poly-γ-Glutamic Acid Hydrogel Mixtures with Basic Drugs or Acidic Drugs: Effect on Ease of Swallowing and Taste Masking

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Pharmacology & Pharmacy 2019年第10期10卷 427-444页

作者： Honami Kojima Saeri Ikegami Shiho Nakamura Haruka Nishikawa Tamami Haraguchi Miyako yoshida minoru Ozeki Ikuo Kawasaki Takahiro Uchida Faculty of Pharmaceutical Sciences Mukogawa Women’s University Nishinomiya Japan

The purpose of this study was to prepare a poly-γ-glutamic acid hydrogel (PGA gel), to examine its ease of swallowing using texture profile analysis (TPA) and to evaluate its taste-masking effects on basic or acidic drugs using the artificial taste sensor. Using TPA, 0.5% and 1.0% PGA gels, 0.5% and 1.0% agar and 1.0% ι-carrageenan in the absence of drug was examined the hardness, adhesiveness and cohesiveness, ranked according to permission criteria published by the Japanese Consumers Affairs Agency. 0.5% PGA gel and 1.0% agar were classified into grade II. In the taste sensor measurement, the bitterness suppressions by 0.5% PGA gel were larger than that by 1.0% agar in all drugs and the bitterness suppressions of basic drugs in 0.5% PGA gel were more potent than those of acidic drugs in 0.5% PGA gel. 1H-nuclear magnetic resonance spectroscopic analysis was carried out to examine the difference in mechanism of bitterness suppression between basic drugs and acidic drugs mixed with PGA gel. The signals of the proton nearest to the nitrogen atom of basic drugs shifted clearly upfield, suggesting an interaction between the amino group of basic drugs and the carboxyl group of PGA gel. In conclusion, PGA gel is expected to be a useful excipient in formulations contained various drugs, especially basic drugs;it also has advantage for not only increasing ease of swallowing but also masking the bitterness of drugs even though a small amount of a single drug dose might be preferred.

关键词： Poly-γ-Glutamic Acid Hydrogel Bitterness Taste Sensor