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Power Quality Disturbance Identification Basing on Adaptive Kalman Filter andMulti-Scale Channel Attention Fusion Convolutional Network

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Energy Engineering 2024年第7期121卷 1865-1882页

作者： Feng Zhao Guangdi liu Xiaoqiang Chen Ying Wang School of Automation and Electrical Engineering Lanzhou Jiaotong UniversityLanzhou730070China

In light of the prevailing issue that the existing convolutional neural network(CNN)power quality disturbance identification method can only extract single-scale features,which leads to a lack of feature information and weak anti-noise performance,a new approach for identifying power quality disturbances based on an adaptive Kalman filter(KF)and multi-scale channel attention(MS-CAM)fused convolutional neural network is *** and composite-disruption signals are generated through *** adaptive maximum likelihood Kalman filter is employed for noise reduction in the initial disturbance signal,and subsequent integration of multi-scale features into the conventional CNN architecture is *** multi-scale features of the signal are captured by convolution kernels of different sizes so that the model can obtain diverse feature *** attention mechanism(ATT)is introduced to adaptively allocate the extracted features,and the features are fused and selected to obtain the new main *** Softmax classifier is employed for the classification of power quality ***,by comparing the recognition accuracy of the convolutional neural network(CNN),the model using the attention mechanism,the bidirectional long-term and short-term memory network(MS-Bi-LSTM),and the multi-scale convolutional neural network(MSCNN)with the attention mechanism with the proposed *** simulation results demonstrate that the proposed method is higher than CNN,MS-Bi-LSTM,and MSCNN,and the overall recognition rate exceeds 99%,and the proposed method has significant classification accuracy and robust classification *** achievement provides a new perspective for further exploration in the field of power quality disturbance classification.

关键词： Power quality disturbance kalman filtering convolutional neural network attention mechanism

SFNet:Stellar Feature Network with CWT for Stellar Spectra Recognition

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Research in Astronomy and Astrophysics 2024年第9期24卷 260-270页

作者： Hao Fu Peng liu Xuan Qi Xue Mei College of Electrical Engineering and Control Science Nanjing Tech UniversityNanjing 211816China

Stellar spectral classification is crucial in astronomical data ***,existing studies are often limited by the uneven distribution of stellar samples,posing challenges in practical *** when balancing stellar categories and their numbers,there is room for improvement in classification *** study introduces a Continuous Wavelet Transform using the Super Morlet wavelet to convert stellar spectra into wavelet images.A novel neural network,the Stellar Feature Network,is proposed for classifying these *** spectra from Large Sky Area Multi-Object Fiber Spectroscopic Telescope DR9,encompassing five equal categories(B,A,F,G,K),were *** experiments validate the effectiveness of the proposed methods and network,achieving significant improvements in classification accuracy.

关键词： methods data analysis-techniques image processing-stars imaging-galaxies stellar content

Valley-dependent transport in a mescoscopic twisted bilayer graphene device

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Chinese Physics B 2024年第1期33卷 61-65页

作者：史文萱刘翰林汪军 School of Physics Southeast UniversityNanjing 210096China

We study the valley-dependent electron transport in a four-terminal mesoscopic device of the two monolayer graphene nanoribbons vertically stacked together, where the intersection forms a bilayer graphene lattice with a controllable twist angle. Using a tight-binding lattice model, we show that the longitudinal and transverse conductances exhibit significant valley polarization in the low energy regime for small twist angles. As the twist angle increases, the valley polarization shifts to the high energy regime. This arises from the regrouping effect of the electron band in the twisted bilayer graphene region. But for relatively large twist angles, no significant valley polarization is observed. These results are consistent with the spectral densities of the twisted bilayer graphene.

关键词： twisted bilayer graphene valley-dependent transport graphene nanoribbon conductance

Olfactory Three-Needle Electroacupuncture Improved Synaptic Plasticity and Gut Microbiota of SAMP8 Mice by Stimulating Olfactory Nerve

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Chinese Journal of Integrative Medicine 2024年第8期30卷 729-741页

作者： WANG Yuan ZHENG A-ni YANG Huan WANG Qiang DAI Biao WANG Jia-ju WAN Yi-tong liu Zhi-bin liu Si-yang College of Acu-moxibustion and Massage Shaanxi University of Chinese MedicineXianyangShaanxi Province712046China Shaanxi Key Laboratory of Acupuncture and Medicine Shaanxi University of Chinese MedicineXianyangShaanxi Province712046China The Second Affiliated Hospital of Shaanxi University of Chinese Medicine XianyangShaanxi Province712000China Department of Traditional Chinese Medicine Baotou Medical CollegeBaotouInner Mongolia Autonomous Region014040China School of Basic Medical Sciences Xi’an Medical UniversityXi’an710021China

Objective To investigate the effects and mechanisms of olfactory three-needle(OTN)electroacupuncture(EA)stimulation of the olfactory system on cognitive dysfunction,synaptic plasticity,and the gut microbiota in senescence-accelerated mouse prone 8(SAMP8)*** Thirty-six SAMP8 mice were randomly divided into the SAMP8(P8),SAMP8+OTN(P8-OT),and SAMP8+nerve transection+OTN(P8-N-OT)groups according to a random number table(n=12 per group),and 12 accelerated senescence-resistant(SAMR1)mice were used as the control(R1)*** was performed at the Yintang(GV 29)and bilateral Yingxiang(LI 20)acupoints of SAMP8 mice for 4 *** Morris water maze test,transmission electron microscopy,terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling(TUNEL)staining,Nissl staining,Golgi staining,Western blot,and 16S rRNA sequencing were performed,*** Compared with the P8 group,OTN improved the cognitive behavior of SAMP8 mice,inhibited neuronal apoptosis,increased neuronal activity,and attenuated hippocampal synaptic dysfunction(P<0.05 or P<0.01).Moreover,the expression levels of synaptic plasticity-related proteins N-methyl-D-aspartate receptor 1(NMDAR1),NMDAR2B,synaptophysin(SYN),and postsynaptic density protein-95(PSD95)in hippocampus were increased by OTN treatment(P<0.05 or P<0.01).Furthermore,OTN greatly enhanced the brain-derived neurotrophic factor(BDNF)/cAMP-response element binding(CREB)signaling and phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin(PI3K/AKT/mTOR)signaling compared with the P8 group(P<0.05 or P<0.01).However,the neuroprotective effect of OTN was attenuated by olfactory nerve *** with the P8 group,OTN had a very limited effect on the fecal microbial structure and composition of SAMP8 mice,while specifically increased the genera Oscillospira and Sutterella(P<0.05).Interestingly,the P8-N-OT group showed an abnormal fecal microbiota with higher microbialα-diversity,Firmicutes/Bacter

关键词： Alzheimer's disease olfactory threeneedle electroacupuncture olfactory nerve synaptic plasticity gut microbiota Chinese medicine

Thymoquinone affects hypoxia-inducible factor-1αexpression in pancreatic cancer cells via HSP90 and PI3K/AKT/mTOR pathways

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World Journal of Gastroenterology 2024年第21期30卷 2793-2816页

作者： Zhan-Xue Zhao Shuai Li Lin-Xun liu Department of General Surgery Qinghai Provincial People's HospitalXining 810007Qinghai ProvinceChina Department of Clinical Pharmacy The Affiliated Hospital of Qinghai UniversityXining 810001Qinghai ProvinceChina

BACKGROUND Pancreatic cancer(PC)is associated with some of the worst prognoses of all major ***(TQ)has a long history in traditional medical practice and is known for its anti-cancer,anti-inflammatory,anti-fibrosis and antioxidant pharmacological *** studies on hypoxia-inducible factor-1α(HIF-1α)and PC have shown that HIF-1αaffects the occurrence and development of PC in many *** addition,TQ could inhibit the development of renal cancer by decreasing the expression of HIF-1α.Therefore,we speculate whether TQ affects HIF-1αexpression in PC cells and explore the *** To elucidate the effect of TQ in PC cells and the regulatory mechanism of HIF-1α*** Cell counting kit-8 assay,Transwell assay and flow cytometry were performed to detect the effects of TQ on the proliferative activity,migration and invasion ability and apoptosis of PANC-1 cells and normal pancreatic duct epithelial(hTERTHPNE)*** real-time polymerase chain reaction and western blot assay were performed to detect the expression of HIF-1αmRNA and protein in PC *** effects of TQ on the HIF-1αprotein initial expression pathway and ubiquitination degradation in PANC-1 cells were examined by western blot assay and *** TQ significantly inhibited proliferative activity,migration,and invasion ability and promoted apoptosis of PANC-1 cells;however,no significant effects on hTERT-HPNE cells were *** significantly reduced the mRNA and protein expression levels of HIF-1αin PANC-1,AsPC-1,and BxPC-3 *** significantly inhibited the expression of the HIF-1αinitial expression pathway(PI3K/AKT/mTOR)related proteins,and promoted the ubiquitination degradation of the HIF-1αprotein in PANC-1 *** had no effect on the hydroxylation and von Hippel Lindau protein mediated ubiquitination degradation of the HIF-1αprotein but affected the stability of the HIF-1αprotein by inhibiting the interaction between HI

关键词： Thymoquinone Pancreatic cancer Hypoxia-inducible factor-1α PI3K/AKT/mTOR HSP90

Surface heterojunction based on n-type low-dimensional perovskite film for highly efficient perovskite tandem solar cells

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National Science Review 2024年第5期11卷 244-253页

作者： Xianyuan Jiang Qilin Zhou Yue Lu Hao Liang wenzhuo Li Qi Wei Mengling Pan Xin wen Xingzhi Wang Wei Zhou Danni Yu Hao Wang Ni Yin Hao Chen Hansheng Li Ting Pan mingyu Ma Gaoqi liu wenjia Zhou Zhenhuang Su Qi Chen Fengjia Fan Fan Zheng Xingyu Gao Qingqing Ji Zhijun Ning School of Physical Science and Technology Shanghai Tech University Department of Modern Physics University of Science and Technology of China i-Lab CAS Key Laboratory of Nanophotonic Materials and Devices Suzhou Institute of Nano-Tech and Nano-Bionics Shanghai Synchrotron Radiation Facility (SSRF) Shanghai Advanced Research InstituteChinese Academy of Sciences

Enhancing the quality of junctions is crucial for optimizing carrier extraction and suppressing recombination in semiconductor devices. In recent years, metal halide perovskite has emerged as the most promising next-generation material for optoelectronic devices. However, the construction of high-quality perovskite junctions, as well as characterization and understanding of their carrier polarity and density,remains a challenge. In this study, using combined electrical and spectroscopic characterization techniques,we investigate the doping characteristics of perovskite films by remote molecules, which is corroborated by our theoretical simulations indicating Schottky defects consisting of double ions as effective charge *** a post-treatment process involving a combination of biammonium and monoammonium molecules, we create a surface layer of n-type low-dimensional perovskite. This surface layer forms a heterojunction with the underlying 3D perovskite film, resulting in a favorable doping profile that enhances carrier extraction. The fabricated device exhibits an outstanding open-circuit voltage(VOC) up to 1.34 V and achieves a certified efficiency of 19.31% for single-junction wide-bandgap（1.77 eV） perovskite solar cells, together with significantly enhanced operational stability, thanks to the improved separation of carriers. Furthermore, we demonstrate the potential of this wide-bandgap device by achieving a certified efficiency of 27.04% and a VOCof 2.12 V in a perovskite/perovskite tandem solar cell configuration.

关键词： perovskite solar cells field effect transistors heterojunction

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此心光明:王阳明“山贼与心贼”说探析

宜春学院学报 2024年第8期46卷 18-23页

作者：刘振文池升明宜春学院马克思主义学院江西宜春336000 中共抚州市委党校江西抚州344000

“山贼与心贼”说是王阳明心学的著名论断,承载着其学术旨趣的精妙独到之处。本文主要通过王阳明在江西平叛前后上书朝廷的奏疏为依据,解析了“山贼与心贼”说的思想渊源,分析了“山贼与心贼”说的实践生成,揭示了“山贼与心贼”说的独... 详细信息

“山贼与心贼”说是王阳明心学的著名论断,承载着其学术旨趣的精妙独到之处。本文主要通过王阳明在江西平叛前后上书朝廷的奏疏为依据,解析了“山贼与心贼”说的思想渊源,分析了“山贼与心贼”说的实践生成,揭示了“山贼与心贼”说的独特学术地位。至此,从百死千难的实践中得来的“山贼与心贼”说,对王阳明具有特殊的意义,不仅成为开示后学的方便法门,而且现实地打通了其前后学术思想的隔阂,也是“良知”所“致”“知行合一”所“合”的最好注脚。

关键词：王阳明山贼心贼此心光明

A proteomic landscape of pharmacologic perturbations for functional relevance

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Journal of Pharmaceutical Analysis 2024年第1期14卷 128-139页

作者： Zhiwei liu Shangwen Jiang Bingbing Hao Shuyu Xie Yingluo liu Yuqi Huang Heng Xu Cheng Luo Min Huang Minjia Tan Jun-Yu Xu State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai201203China School of Chinese Materia Medica Nanjing University of Chinese MedicineNanjing210023China Zhongshan Institute for Drug Discovery Shanghai Institute of Materia MedicaChinese Academy of SciencesZhongshanGuangdong528400China State Key Laboratory of Pharmaceutical Biotechnology Nanjing UniversityNanjing210023China

Pharmacological perturbation studies based on protein-level signatures are fundamental for drug discovery. In the present study, we used a mass spectrometry (MS)-based proteomic platform to profile the whole proteome of the breast cancer MCF7 cell line under stress induced by 78 bioactive compounds. The integrated analysis of perturbed signal abundance revealed the connectivity between phenotypic behaviors and molecular features in cancer cells. Our data showed functional relevance in exploring the novel pharmacological activity of phenolic xanthohumol, as well as the noncanonical targets of clinically approved tamoxifen, lovastatin, and their derivatives. Furthermore, the rational design of synergistic inhibition using a combination of histone methyltransferase and topoisomerase was identified based on their complementary drug fingerprints. This study provides rich resources for the proteomic landscape of drug responses for precision therapeutic medicine.

关键词： Proteomics Drug Perturbation Drug target Drug combination

Recent advances in switchable surfactants for heavy oil production:A review

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Energy Geoscience 2024年第4期5卷 75-88页

作者： Qi Li Lingfei liu Dejun Sun Zhenghe Xu Key Laboratory of Colloid and Interface Chemistry Ministry of EducationSchool of Chemistry and Chemical EngineeringShandong UniversityJinanShandong250100PR China Shenzhen Key Laboratory of Interfacial Science and Engineering of Materials Department of Materials Science and EngineeringSouthern University of Science and TechnologyShenzhenGuangdong518055PR China Key Laboratory of Tertiary Oil Recovery and Oilfield Chemistry PetroChina Dagang Oilfield CompanyTianjin300280PR China

Surfactants are extensively employed in the cold production of heavy ***,producing heavy oil emulsions using conventional surfactants poses a challenge to spontaneous demulsification,necessitating the addition of demulsifiers for oil-water *** inevitably increases the exploitation cost and environmental pollution *** surfactants have garnered much attention due to their dual capabilities of underground heavy oil emulsification and surface *** study focuses on the fundamental working principles and classification of novel switchable surfactants for oil displacement developed in recent *** offers a comprehensive overview of the latest advances in the applications of switchable surfactants in the fields of enhanced oil recovery(EOR),oil sand washing,and oil-water ***,it highlights the existing challenges and future development directions of switchable surfactants for heavy oil recovery.

关键词： Heavy oil Switchable surfactant Cold production Emulsification Demulsification