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Allelopathic potentials of surrounding vegetation on seedling establishment of alpine cushion Arenaria polytrichoides

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Journal of Plant Ecology 2024年第2期17卷 146-160页

作者： Xu-Fang Chen Li-Shen Qian Hong-Hua Shi Ya-Zhou Zhang min-shu song Hang Sun Jian-Guo Chen Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina University of Chinese Academy of Sciences Beijing 101408China

When facilitating other species and sustaining plant community structures and biodiversity,alpine cushion plants simultaneously experience negative feedback effects from surrounding ***,the impact of surrounding vegetation on cushion dynamics remains poorly understood,particularly in terms of allelopathic *** investigate the allelopathic potentials of surrounding vegetation on seedling establishment of the typical cushion plant Arenaria polytrichoides *** an elevational gradient,we extracted potential allelopathic compounds and tested their impacts on seed germination and seedling growth of *** addition,exclusion experiments using activated carbon were conducted to further elucidate these *** results demonstrate that surrounding vegetation exhibits certain allelopathic potentials on *** seedling establishment,with variations observed based on elevation,source and concentration of allelopathy compounds,as well as growing ***,low-elevation vegetation exerts pronounced suppression on seedling ***,higher-elevation vegetation generally shows no effect on seed germination but stimulates seedling growth through allelopathy ***,aboveground vegetation predominantly inhibits both seed germination and seedling growth in low-elevation communities;however,the effects of belowground vegetation depend on elevation and extract concentration *** identifed allelopathic potentials of surrounding vegetation signifcantly infuence the population dynamics of cushion *** by potentially accelerating population degeneration in lower-elevation communities while ensuring consistent population recruitment and expansion in higher-elevation communities.

关键词： allelopathic potential community dynamic cushion plant seed germination seedling growth

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The recruitment of exogenous endothelial progenitor cells in lung tumor model of nude mice

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Chinese Journal of Cancer 2010年第11期29卷 952-958页

作者： Qiang Peng ming Liu shu-min song Xian-Hua Li Yi-Hua Du Yong Zhi min-Yong Wang Department of Surgery Affiliated Hospital of Luzhou Medical College Luzhou Sichuan 646000 P. R. China Physiology Laboratory Luzhou Medical College Luzhou Sichuan 646000 P. R. China Central Laboratory Luzhou Medical College Luzhou Sichuan 646000 P. R. China

Background and Objective: Endothelial progenitor cells (EPCs) play an important role in hypoxia-triggered tumor vasculogenesis. However, the homing of exogenous EPCs in tumors is still unclear. In this study, we investigated the recruitment of exogenous EPCs in human lung adenocarcinoma model of nude mice. Methods: EPCs labeled with green fluorescence protein (GFP) were transplanted into nude mice bearing human lung adenocarcinoma. The growth of tumor was observed. After the mice were killed, GFP-EPCs in different tissues were examined by fluorescence. The tumor tissues were stained for CD133, hypoxia-inducible factor-1alpha (HIF-1α), stromal cell-derived factor-1α (SDF-1α), and vascular endothelial growth factor receptor (KDR). Real-time polymerase chain reaction of CD133, HIF-1α, SDF-1α, and VEGF-1 were also performed. Results: The growth of tumor in EPC group was significantly faster than that in saline solution group (P < 0.05). Under fluorescence microscope, GFP-EPCs were strongly expressed in both tumor and bone marrow. EPCs were recruited to the tumor periphery to participate in tumor vasculogenesis. The expression of CD133, HIF-1α, and SDF-1 mRNA in tumor and bone marrow were significantly higher than that in the liver, spleen, and skin (P < 0.05). Conclusions: Exogenous EPCs can be recruited to tumor and accelerate tumor growth. Except tumor, bone marrow can also recruit EPCs.

关键词：内皮祖细胞肺肿瘤外源性血管内皮生长因子受体缺氧诱导因子-1α 裸鼠招聘模型

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Concise extraction and characterization of the pore-throat network in unconventional hydrocarbon reservoirs: A new perspective

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Petroleum Science 2024年第3期21卷 1474-1487页

作者： shu-Heng Du Yong-min Shi State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing100190China School of Engineering Science University of Chinese Academy of SciencesBeijing100049China School of Earth and Space Sciences Peking UniversityBeijing100871China

In this study,a new image-based method for the extraction and characterization of pore-throat network for unconventional hydrocarbon storage and exploitation is proposed.“Pore-throat solidity”,which is analogous to particle solidity,and a new method for automatic identification of pores and throats in tight sandstone oil reservoirs are ***,the“pore-throat combination”and“pure pore”are defined and distinguished by drawing the cumulative probability curve of the pore-throat solidity and by selecting an appropriate cutoff *** the discrete grid set is recognized as a pore-throat combination,Legendre ellipse fitting and minimum Feret diameter are *** the pore and throat grid sets are identified as pure pores,the pore diameter can be directly *** the new method,the analytical results for the physical parameters and pore radius agree well with most prior *** results comparing the maximum ball and the new model could also prove the accuracy of the latter's in micro and nano *** new model provides a more practical theoretical basis and a new calculation method for the rapid and accurate evaluation of the complex processes of oil migration.

关键词： Hydrocarbon exploitation Pore Throat Porous media Identification

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Comparison of models to predict air infiltration rate of buildings with different surrounding environments

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Building Simulation 2024年第6期17卷 1007-1021页

作者： shu Zheng Xiujiao song Lin Duanmu Yu Xue Xudong Yang Department of Building Science Tsinghua UniversityBeijing100084China School of Civil Engineering Dalian University of TechnologyDalian116024China Shanxi Research Institute for Clean Energy Tsinghua UniversityTaiyuan030032China

The air infiltration rate of buildings strongly influences indoor environment and energy *** this study,several traditional methods for determining the air infiltration rate were compared,and their accuracy in different scenarios was ***,a method combining computational flow dynamics(CFD)with the Swami and Chandra(S-C)model was developed to predict the influence of the surrounding environment on the air infiltration *** buildings in Dalian,China,were selected:one with a simple surrounding environment and the other with a complex surrounding environment;their air infiltration rates were *** test results were used to validate the accuracy of the air infiltration rate solution models in different urban *** the building with a simple environment,the difference between the simulation and experimental results was 0.86%–22.52%.For the building with a complex environment,this difference ranged from 17.42%to 159.28%.We found that most traditional models provide accurate results for buildings with simple surrounding and that the simulation results widely vary for buildings with complex *** results of the method of combining CFD with the S-C model were more accurate,and the relative error between the simulation and test results was 10.61%.The results indicate that the environment around the building should be fully considered when calculating the air infiltration *** results of this study can guide the application of methods of determining air infiltration rate.

关键词： air infiltration rate models CFD simulation building surrounding air infiltration rate test

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Microstructure evolution and mechanical properties of brazing joint for ultra-thin-walled Inconel 718 considering grain size effect and brazing temperature

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Chinese Journal of Aeronautics 2024年第2期37卷 541-556页

作者： Rui ZHAO Yueshuai song Hui KANG min WAN School of Mechanical Engineering and Automation Beihang UniversityBeijing 100191China Jiangxi Research Institute of Beihang University Jiangxi 330000China

The systematic investigation of the mechanical properties and microstructure evolution process of ultra-thin-walled Inconel 718 capillary brazing joints is of great significance because of the exceptionally high demands on its *** achieve this objective,this study investigates the impact of three distinct brazing temperatures and five typical grain sizes on the brazed joints’mechanical properties and microstructure evolution *** evolution analysis was conducted based on Electron Back Scatter Diffraction(EBSD),Scanning Electron Microscopy(SEM),X-Ray Diffraction(XRD),High-Resolution Transmission Electron Microscopy(HRTEM),and Focused Ion Beam(FIB).Besides,the mechanical properties and fracture behavior were studied based on the uniaxial tension tests and in-situ tension *** findings reveal that the brazing joint’s strength is higher for the fine-grain capillary than the coarse-grain one,primarily due to the formation of a dense branch structure composed of G-phase in the brazing *** effects of grain size,such as pinning and splitting,are amplified at higher brazing ***,micro-cracks initiate around brittle intermetallic compounds and propagate through the eutectic zone,leading to a cleavage fracture *** fracture stress of fine-grain specimens is higher than that of coarse-grain due to the complex micro-crack ***,this study contributes significantly to the literature by highlighting the crucial impact of grain size on the brazing properties of ultra-thin-walled Inconel 718 structures.

关键词： EYWORDS Ultra-thin-walled structure Brazing Inconel 718 Grain size effect Brazing temperature

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Adaptation of Ocular Opponency Neurons Mediates Attention-Induced Ocular Dominance Plasticity

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Neuroscience Bulletin 2024年第3期40卷 339-349页

作者： Fangxing song Lili Lyu min Bao CAS Key Laboratory of Behavioral Science Institute of PsychologyChinese Academy of SciencesBeijing100101China Department of Psychology University of Chinese Academy of SciencesBeijing100049China Institute of Neuroscience Key Laboratory of Primate NeurobiologyCAS Center for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghai200031China

Previous research has shown that ocular dominance can be biased by prolonged attention to one *** ocular-opponency-neuron model of binocular rivalry has been proposed as a candidate account for this *** direct neural evidence is still *** manipulating the contrast of dichoptic testing gratings,here we measured the steady-state visually evoked potentials(SSVEPs)at the intermodulation frequencies to selectively track the activities of ocular-opponency-neurons before and after the“dichoptic-backward-movie”*** hour of adaptation caused a shift of perceptual and neural ocular dominance towards the unattended *** importantly,we found a decrease in the intermodulation SSVEP response after adaptation,which was significantly greater when high-contrast gratings were presented to the attended eye than when they were presented to the unattended *** results strongly support the view that the adaptation of ocular-opponency-neurons contributes to the ocular dominance plasticity induced by prolonged eye-based attention.

关键词： Attention Ocular dominance Opponency neuron Adaptation Steady-state visually evoked potential

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Top-quark rare decays with flavor violation

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Chinese Physics C 2024年第9期48卷 68-81页

作者： ming-Yue Liu shu-min Zhao song Gao Xing-Yu Han Tai-Fu Feng Department of Physics Hebei UniversityBaoding 071002China Hebei Key Laboratory of High-precision Computation and Application of Quantum Field Theory Baoding 071002China Hebei Research Center of the Basic Discipline for Computational Physics Baoding 071002China Department of Physics Chongqing UniversityChongqing 401331China

In the present study,we investigated the decays of the top quark:t→cy,t→cg,t→cZ,and t→*** are extremely rare processes in the standard model(SM).As the U(1)extension of the minimal supersymmetric standard model(MSSM),the U(1)_X SSM features new superfields such as the right-handed neutrinos and three Higgs *** analyzed the effects of different sensitive parameters on the results and made reasonable theoretical predictions,thereby providing a useful reference for future experimental *** the constraint set by the updated experimental data,the numerical results show that the branching ratios of the four proccsscs,i.e.,t→cγ,cg,cZ,ch,can reach the same order of magnitude as their experimental upper *** them,tanβhas the most evident effect on these processes and is the main parameter;g_(X),g_(YX),μ,M_(2),λ_(H),M_(U23)^(2),and M_(Q23)^(2) are also important parameters for the processes,and have effects on the numerical results.

关键词： Top quark flavor violation U(1)_(X)SSM new physics

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A condition-based maintenance policy for reconfigurable multi-device systems

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Advances in Manufacturing 2024年第2期12卷 252-269页

作者： shu-Lian Xie Feng Xue Wei-min Zhang Jia-Wei Zhu School of Mechanical Engineering Tongji UniversityShanghai201804People’s Republic of China

The exploration of component states for optimizing maintenance schedules in complex systems has garnered significant interest from ***,current literature usually overlooks the critical aspects of system flexibility and *** implementation of system reconfiguration can effectively mitigate system downtime and enhance production *** study proposes a dynamic condition-based maintenance policy considering reconfiguration for reconfigurable systems.A double-layer decision rule was constructed for the devices and *** achieve the best overall maintenance effect of the system,the remaining useful life probability distribution and recommended maintenance time of each device were used to optimize the concurrent maintenance time window of the devices and determine whether to reconfigure them.A comprehensive maintenance efficiency index was introduced that simultaneously considered the maintenance cost rate,reliability,and availability of the system to characterize the overall maintenance *** reconfiguration cost was included in the maintenance *** proposed policy was tested through numerical experiments and compared with different-level *** results show that the proposed policy can significantly reduce the downtime and maintenance costs and improve the overall system reliability and availability.

关键词： Condition-based maintenance(CBM) Reconfigurable system Remaining useful life Maintenance cost System reliability

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Discovery of TK-642 as a highly potent,selective,orally bioavailable pyrazolopyrazine-based allosteric SHP2 inhibitor

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3624-3642页

作者： Kai Tang shu Wang Siqi Feng Xinyu Yang Yueyang Guo Xiangli Ren Linyue Bai Bin Yu Hong-min Liu Yihui song School of Pharmaceutical Sciences&Key Laboratory of Advanced Drug Preparation Technologies Ministry of EducationZhengzhou UniversityZhengzhou 450001China College of Chemistry Pingyuan LaboratoryState Key Laboratory of Antiviral DrugsZhengzhou UniversityZhengzhou 450001China Tianjian Laboratory of Advanced Biomedical Sciences Institute of Advanced Biomedical SciencesZhengzhou UniversityZhengzhou 450000China State Key Laboratory of Pharmaceutical Biotechnology Nanjing UniversityNanjing 210023China

Src homology-2-containing protein tyrosine phosphatase 2(SHP2)is a promising therapeutic target for cancer *** this work,we presented the structure-guided design of 5,6-fused bicyclic allosteric SHP2 inhibitors,leading to the identification of pyrazolopyrazine-based TK-642 as a highly potent,selective,orally bioavailable allosteric SHP2 inhibitor(SHP2WT IC_(50)=2.7 nmol/L)with favorable pharmacokinetic profiles(F=42.5%;t_(1/2)=2.47 h).Both dual inhibition biochemical assay and docking analysis indicated that TK-642 likely bound to the“tunnel”allosteric site of ***-642 could effectively suppress cell proliferation(KYSE-520 cells IC_(50)=5.73μmol/L)and induce apoptosis in esophageal cancer cells by targeting the SHP2-mediated AKT and ERK signaling ***,oral administration of TK-642 also demonstrated effective anti-tumor effects in the KYSE-520 xenograft mouse model,with a T/C value of 83.69%.Collectively,TK-642 may warrant further investigation as a promising lead compound for the treatment of esophageal cancer.

关键词： Protein tyrosine phosphatase Pyrazolopyrazine SHP2 inhibitor Esophageal cancer

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Nonlocal coherence harvesting from quantum vacuum

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Communications in Theoretical Physics 2024年第7期76卷 44-51页

作者： Rui-Di Wang shu-min Wu Xiao-Li Huang Department of Physics Liaoning Normal UniversityDalian 116029China

It is well known that nonlocal coherence reflects nonclassical correlations better than quantum entanglement. Here, we analyze nonlocal coherence harvesting from the quantum vacuum to particle detectors adiabatically interacting with a quantum scalar field in minkowski *** find that the harvesting-achievable separation range of nonlocal coherence is larger than that of quantum entanglement. As the energy gap grows sufficiently large, the detectors harvest less quantum coherence, while the detectors could extract more quantum entanglement from the vacuum state. Compared with the linear configuration and the scalene configuration, we should choose the model of equilateral triangle configuration to harvest tripartite coherence from the vacuum. Finally, we find a monogamous relationship, which means that tripartite l_(1)-norm of coherence is essentially bipartite types.

关键词： nonlocal coherence quantum vacuum monogamous relationship

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