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Electrical stress and acid orange 7 synergistically clear the blockage of electron flow in the methanogenesis of low-strength wastewater

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Environmental Science and Ecotechnology 2024年第4期20卷 291-299页

作者： Ze-Chong Guo min-hua cui Chun-Xue Yang Hong-Liang Dai Tong-Yi Yang Lin-Zhi Zhai Yong Chen Wen-Zong Liu Ai-Jie Wang School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang212100China State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin150090China Jiangsu Key Laboratory of Anaerobic Biotechnology Jiangnan UniversityWuxi214122China School of Civil and Environmental Engineering Harbin Institute of TechnologyShenzhen518055China School of Geography and Tourism Harbin UniversityHarbin150001China School of Environmental Science and Engineering Huazhong University of Science and TechnologyWuhan430074China

Energy recovery from low-strength wastewater through anaerobic methanogenesis is constrained by limited substrate *** development of efficient methanogenic communities is critical but *** we develop a strategy to acclimate methanogenic communities using conductive carrier(CC),electrical stress(ES),and Acid Orange 7(AO7)in a modified *** synergistic integration of CC,ES,and AO7 precipitated a remarkable 72-fold surge in methane production rate compared to the *** increase was attributed to an altered methanogenic community function,independent of the continuous presence of AO7 and ***7 acted as an external electron acceptor,accelerating acetogenesis from fermentation intermediates,restructuring the bacterial community,and enriching electroactive bacteria(EAB).Meanwhile,CC and ES orchestrated the assembly of the archaeal community and promoted electrotrophic methanogens,enhancing acetotrophic methanogenesis electron flow via a mechanism distinct from direct electrochemical *** collective application of CC,ES,and AO7 effectively mitigated electron flow impediments in low-strength wastewater methanogenesis,achieving an additional 34%electron recovery from the *** study proposes a new method of amending anaerobic digestion systems with conductive materials to advance wastewater treatment,sustainability,and energy self-sufficiency.

关键词： Methanogenesis Conductive carrier Electrical stress Acid orange 7 Electron transfer

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Intelligent Setting and Optimization of Process Parameters for Plastic Injection Molding

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Computer Aided Drafting,Design and Manufacturing 2006年第1期16卷 1-16页

作者： FENG Wei ZHOU hua-min cui Shu-biao LI De-qun State Key Laboratory of Plastic Forming Simulation and Die ＆ Mold Technology Huazhong University of Science and Technology Wuhan 430074 China

An intelligent model employing case-based reasoning（CBR） and fuzzy inference was constructed in terms to the system characteristics of plastic injection molding and considering the molding personnel＇s thought during the molding trial-runs. The model describes the complex process of injection molding with a view to the characters and advantages of CBR and fuzzy theory. And it can be used to determine the initial process parameters and optimize the process parameters on-line. The key implementation technologies of the model are described in detail, including determining the initial process parameters based on CBR, correcting defects, optimizing process parameters based on fuzzy inference, etc. A corresponding intelligent system was developed which is integrated with injection machine by communicating with the controller.

关键词： injection molding case-based reasoning(CBR) fuzzy inference process parameters

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Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury

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Neural Regeneration Research 2025年第2期20卷 587-597页

作者： Tong Li Hui-min Xing Hai-Dong Qian Qiao Gao Sheng-Lan Xu hua Ma Zai-Long Chi State Key Laboratory of Ophthalmology Optometry and Visual ScienceEye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina

Several studies have found that transplantation of neural progenitor cells(NPCs)promotes the survival of injured ***,a poor integration rate and high risk of tumorigenicity after cell transplantation limits their clinical *** extracellular vesicles(sEVs)contain bioactive molecules for neuronal protection and *** studies have shown that stem/progenitor cell-derived sEVs can promote neuronal survival and recovery of neurological function in neurodegenerative eye diseases and other eye *** this study,we intravitreally transplanted sEVs derived from human induced pluripotent stem cells(hiPSCs)and hiPSCs-differentiated NPCs(hiPSC-NPC)in a mouse model of optic nerve *** results show that these intravitreally injected sEVs were ingested by retinal cells,especially those localized in the ganglion cell *** with hiPSC-NPC-derived sEVs mitigated optic nerve crush-induced retinal ganglion cell degeneration,and regulated the retinal microenvironment by inhibiting excessive activation of *** analysis further revealed that hiPSC-NPC derived sEVs transported neuroprotective and anti-inflammatory miRNA cargos to target cells,which had protective effects on RGCs after optic nerve *** findings suggest that sEVs derived from hiPSC-NPC are a promising cell-free therapeutic strategy for optic neuropathy.

关键词： exosome miRNA neural progenitor cell neurodegeneration neuroinflammation neuroprotection optic nerve crush optic neuropathy retinal ganglion cell small extracellular vesicles

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Self-assembled carbon monoxide nanoprodrug for chemiexcitationtriggered synergistic chemotherapy against breast cancer

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Science China Chemistry 2025年

作者： Shunfei cui Yiyao Pan Chenzhe Ma Bin Qi Qingqiang min ming Li huabing Chen Hengte Ke Xingyue Ji Jiangsu Province Engineering Research Center of Precision Diagnostics and Therapeutics Development College of Pharmaceutical ScienceSoochow University

Carbon monoxide（CO） has recently been well-established as a promising therapeutic modality against cancer. The development of transition-metal-free and tumor-targeted delivery platforms for CO is highly demanded but remains very sporadic. Herein, we developed a polyprodrug system for the co-delivery of CO and a chemotherapeutic agent combretastin A-4（CA-4） to the tumor site based on a chemiexcitation mechanism. Such a poly-prodrug successfully achieved the co-activation of CO and CA-4 in response to H2O2at the tumor site both in vitro and in vivo. Importantly, a synergist effect between CO and CA-4 was observed in suppressing tumor growth in a mouse tumor model. It is anticipated that such a poly-prodrug system could be potentially adapted for the co-delivery of CO and another drug payload for combinational therapy for other indications.

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Orientation gradient on surface of non-oriented electrical steel annealed by γ → α transformation

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Journal of Iron and Steel Research International 2020年第1期27卷 88-95页

作者： Jin-hua Wang Ping Yang Wei-min Mao Feng-e cui School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China

The microstructures and textures of the non-oriented electrical steel sheets under various annealing conditions were *** orientation gradient in the interior of grains appeared on the surface of steel sheets after α→γ→α transformation in various *** orientation gradient that appeared on the surface was inherited into the center of the steel sheet in H2 atmosphere,while that appeared only in the grains of the surface layer during γ→α transformation with N2 *** thin oxide scale was generated in various atmospheres containing traces of O2 and *** formation mechanism of orientation gradient is related to the thermal stress caused by the difference of thermal expansion coefficients between the oxide scale and the thin ferrite on the *** combined effect of phase transformation stress and thermal stress caused the plastic deformation of the thin ferrite grains on the surface in the initial stage of γ→α transformation,and then the orientations of the thin ferrite grains gradually rotated and caused the orientation gradient in the interior of grains.

关键词： Electrical steel Texture Phase transformation-Thermal stress Oxide scale

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Effectiveness of hot deformation and subsequent annealing forβgrain refinement of Ti-5Al-5Mo-5V-1Cr-1Fe titanium alloy

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Rare Metals 2021年第12期40卷 3608-3615页

作者： Yi-min cui Wei-Wei Zheng Chao-hua Li Guan-hua Cao Yan-Dong Wang State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing 100083China

High strength titanium alloys suffer from a limited combination of strength and *** their micro structure,the coarseβgrain is a detrimental *** the present study,the effects of hot deformation and annealing treatment on theβgrain refinement of Ti-5 Al-5 Mo-5 V-1 Cr-1 Fe(TC18)titanium alloy have been investigated by using electronic backscattered diffraction(EBSD)and transmission electric microscopy(TEM).Hot compression tests of TC18 alloy were performed between 1073 and 1223 K at strain rates of 0.01 and 0.10 s^(-1)·Subsequent annealing treatments were conducted to investigate the effect of deformation microstructure on the recrystallization behavior ofβ*** results indicate that dynamic recovery(DRV)is the dominant restoration mechanism during hot *** dynamic recrystallization(dDRX)is significantly limited at a higher temperature in theβregion,whereas continuous dynamic recrystallization(cDRX)of theβphase is observed at a higher strain rate in the(α+β)*** final annealing microstructure is highly dependent on the deformation *** dDRX during hot deformation could not effectively refine theβ*** refined and uniformβgrains with an average grain size of 12μm are achieved by combining hot deformation and subsequent annealing in the(α+β)*** study provides a guide for theβgrain refinement of high strength titanium alloys.

关键词： Grain refinement Dynamic recrystallization Hot deformation High strength titanium alloy

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Automated process parameters tuning for an injection moulding machine with soft computing

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第3期12卷 201-206页

作者： Peng ZHAO Jian-zhong FU hua-min ZHOU Shu-biao cui State Key Laboratory of Fluid Power Transmission and Control Zhejiang University Hangzhou 310027 China State Key Laboratory of Material Processing and Die & Mould Technology Huazhong University of Science and Technology Wuhan 430074 China

In injection moulding production,the tuning of the process parameters is a challenging job,which relies heavily on the experience of skilled *** this paper,taking into consideration operator assessment during moulding trials,a novel intelligent model for automated tuning of process parameters is *** consists of case based reasoning (CBR),empirical model (EM),and fuzzy logic (FL) *** and EM are used to imitate recall and intuitive thoughts of skilled operators,respectively,while FL is adopted to simulate the skilled operator optimization ***,CBR is used to set up the initial process *** CBR fails,EM is employed to calculate the initial ***,a moulding trial is performed using the initial *** FL is adopted to optimize these parameters and correct defects repeatedly until the moulded part is found to be *** on the above methodologies,intelligent software was developed and embedded in the controller of an injection moulding *** results show that the intelligent software can be effectively used in practical production,and it greatly reduces the dependence on the experience of the operators.

关键词： Injection moulding machine (IMM) Process parameters Case based reasoning (CBR) Empirical model (EM) Fuzzy logic (FL)

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Structure and properties of ZrCoCe getter film with Pd protection layer

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Rare Metals 2021年第9期40卷 2579-2583页

作者： Jian-Dong cui hua-Ting Wu Yan Zhang Yao-hua Xu Zhi-min Yang Advanced Electronic Materials Institute GRIMAT Engineering Institute Co.LtdBeijing 101407China

ZrCoCe getter films with thickness of ~2.3 lm were deposited on Si(100) wafers by direct current(DC)magnetron sputtering process. A 400-nm-thick Pd protection layer was then deposited on the as-deposited ZrCoCe film without exposure to atmosphere. Microstructure, surface morphology and surface chemical state of the films were analyzed. Moreover, hydrogen sorption properties were determined. The results show that the ZrCoCe film displays a cauliflower-like morphology and a porous columnar-like structure which is composed of nanocrystal grains. The Pd protection layer tightly adheres to the surface of the ZrCoCe film and efficiently prevents the oxidation of Zr under exposure to atmosphere. We find that the hydrogen sorption properties of the Pd-ZrCoCe film are significantly improved,in comparison with those of the as-deposited ZrCoCe film.

关键词： Getter films ZrCoCe Protection layer Sorption property

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Universal design of three-dimensional porous graphene-iron based promotors for kinetically rationalized lithium-sulfur chemistry

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Journal of Energy Chemistry 2025年第1期100卷 192-200页

作者： hua Gao Yunfeng Zhang Menglei Wang Ruoxuan Yang Shuai Feng Xuan Cao Yaping Zhang Zhongyuan Lu Yingze Song State Key Laboratory of Environment-Friendly Energy Materials School of Materials and Chemistry Southwest University of Science and Technology School of Material Science and Engineering Henan University of Technology College of Chemistry and Chemical Engineering Taishan University

Lithium-sulfur （Li-S） batteries are widely deemed to be one of the most potential candidates for future secondary batteries because of their remarkable energy ***,notorious polysulfide shuttling and retarded sulfur reaction kinetics pose significant obstacles to the further application of Li-S *** rationally designed highly active electrocatalysts can facilitate polysulfide conversion,the universal and scalable synthesis strategies need to be ***,a universal synthetic strategy to construct a series of three-dimensional （3D） porous graphene-iron （3DGr-Fe） based electrocatalysts involving 3DGr-FeP,3DGr-Fe3C,and 3DGr-Fe3Se4is exploited for manipulating the Li-S redox *** has been observed that the implementation of a 3D porous Gr architecture leads to the well-designed conductive networks,while the uniformly dispersed iron nanoparticles introduce an abundance of active sites,fostering the lithium polysulfide conversion,thereby bolstering the overall electrochemical *** Li-S battery with the 3DGr-Fe based electrocatalyst exhibits remarkable capacity retention of 94.8%upon 100 times at 0.2 ***,the soft-packaged Li-S pouch cell based on such a 3DGr-Fe electrocatalyst delivers superior capacity of 1060.71 mA h g-1and guarantees for the continuous 30 min work of fan *** investigation gives comprehensive insights into the design,synthesis,and mechanism of 3DGr-Fe based electrocatalysts with high activity toward efficient and durable Li-S batteries.

关键词： Redox reactions

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脂质转移蛋白SiLTP1基因参与谷子耐盐响应初探

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作物学报 2025年第1期51卷 58-67页

作者：孟凡花刘敏沈傲刘炜山东省农业科学院农作物种质资源研究所山东济南250100 上海应用技术大学生态技术与工程学院上海201418

土壤盐渍化严重制约农业生产发展,通过提高植物耐盐性进行盐碱地综合利用,对于保障粮食安全,提升农业生产效率具有重要意义。脂质转移蛋白是一类在高等植物中广泛存在的小分子蛋白质,能够参与植株生长、信号转导以及多种生物和非生物胁... 详细信息

土壤盐渍化严重制约农业生产发展,通过提高植物耐盐性进行盐碱地综合利用,对于保障粮食安全,提升农业生产效率具有重要意义。脂质转移蛋白是一类在高等植物中广泛存在的小分子蛋白质,能够参与植株生长、信号转导以及多种生物和非生物胁迫过程。前期本课题组克隆到一个谷子中编码脂质转移蛋白的基因SiLTP1,本研究通过构建其原核表达载体和植物双元过表达载体,获得了该基因的原核表达蛋白及同源转化过表达阳性植株,经进一步筛选获得4个纯合株系。体外耐盐性试验显示, SiLTP1的原核表达蛋白具有一定耐盐性;转基因植株苗期耐盐生理指标测定显示,SiLTP1过表达植株在遭受盐胁迫时,植株体内MDA积累减少,抗氧化酶含量升高,可积累更少的过氧化氢,从而降低胁迫对植株的氧化损伤,显示基因过表达植株具有更好的耐盐性。本研究结果初步揭示, SiLTP1可正向调控谷子的耐盐性,其在谷子耐盐抗逆方面具有潜在功能,为耐盐谷子品种改良及新品种培育提供了理论基础和候选基因资源。

关键词：脂质转移蛋白 SiLTP1 盐胁迫谷子耐盐响应

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