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Synthetic Time Series Genera.ion Model for a.a.ysis of Power System Opera.ion a.d Expa.sion with High Renewa.le Energy Penetra.ion

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Journa. of Modern Power Systems a.d Clea. Energy 2021年第4期9卷 849-858页

作者： Rodrigo Pa.ma.Behnke Jorge Vega.herrera Felipe Va.encia.Osca. Nunez-Ma.a Energy Center Department of Electrical EngineeringFaculty of Mathematical and Physical SciencesUniversity of ChileSantiagoChile Depa.tment of Electrica. Engineering University of AntofagastaAntofagastaChile School of Electrica. Engineering University of Costa RicaSan PedroCosta Rica

The increa.ing integra.ion of renewa.le energy sources into current power systems ha. posed the cha.lenge of a.equa.ely representing the sta.istica. properties a.socia.ed with their va.ia.le power genera.ion. In this pa.er, a.novel procedure is proposed to select a.proper synthetic time series genera.ion model for renewa.le energy sources to a.a.yze power system problems. The procedure ta.es a.va.ta.e of the objective of the specific a.a.ysis to be performed a.d the sta.istica. cha.a.teristics of the a.a.la.le time series. The a.m is to determine the suita.le model to be used for genera.ing synthetic time series of renewa.le energy sources. a.set of indica.ors is proposed to verify tha. the sta.istica. properties of synthetic time series fit the sta.istica. properties of the origina. da.a. The proposa. ca. be integra.ed into systema.ic tools a.a.la.le for da.a.a.a.ysis without compromising the representa.ion of the sta.istica. properties of the origina. time series. The procedure is tested using rea. da.a.from the New Zea.a.d power system in a.mid-term a.a.ysis on integra.ing wind power pla.ts into the power system. The results show tha. the proposed procedure reduces the error obta.ned in a.a.yzing power systems compa.ed with reference models.

关键词： Time series a.a.ysis renewa.le energy source sola. energy stocha.tic process sta.istica. a.a.ysis wind energy

Role of gene polymorphisms in ga.tric ca.cer a.d its precursor lesions:Current knowledge a.d perspectives in La.in a.erica. countries

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World Journa. of Ga.troenterology 2014年第16期20卷 4503-4515页

作者： miguel a.gel Chiurillo La.ora.orio de Genética.Molecula. "Dr.Jorge Yunis-Turba." Decanato de Ciencias de la SaludUniversidad Centroccidental Lisandro AlvaradoBarquisimeto 3001Venezuela

La.in a.erica.shows one of the highest incidence ra.es of ga.tric ca.cer in the world,with va.ia.ions in morta.ity ra.es a.ong na.ions or even within countries belonging to this *** ca.cer is the result of a.multifa.toria. complex process,for which a.multistep model of ca.cinogenesis is currently *** to the infection with Helicoba.ter pylori,tha. pla.s a.ma.or role,environmenta. fa.tors a. well a. genetic susceptibility fa.tors a.e significa.t pla.ers a. different sta.es in the ga.tric ca.cer *** differences in popula.ion origin,demogra.hic structure,socio-economic development,a.d the impa.t of globa.iza.ion lifestyles experienced in La.in a.erica.in the la.t deca.es,a.l together offer opportunities for studying in this context the influence of genetic polymorphisms in the susceptibility to ga.tric *** a.m of this a.ticle is to discuss current trends on ga.tric ca.cer in La.in a.erica. countries a.d to review the a.a.la.le published informa.ion a.out studies of a.socia.ion of gene polymorphisms involved in ga.tric ca.cer susceptibility from this region of the world.a.tota. of 40 genes or genomic regions a.d69 genetic va.ia.ts,58%representing ma.kers involved in infla.ma.ory response,ha.e been used in a.number of studies in which predomina.es a.low number of individua.s(ca.es a.d controls)*** of IL-1B(-511 C/T,14 studies;-31 T/C,10 studies)a.d IL-1RN(va.ia.le number of ta.dem repea.s,17 studies)a.e the most represented ones in the reviewed *** genetic va.ia.ts recently eva.ua.ed in la.ge meta.na.yses a.d a.socia.ed with ga.tric ca.cer risk were a.so a.a.yzed in a.few studies[e.g.,prosta.e stem cell a.tigen(PSCa.,CDH1,Survivin].Further a.d better a.a.ysis centered in gene polymorphisms linked to other cova.ia.es,epidemiologica. studies a.d the informa.ion provided by meta.a.a.yses a.d genome-wide a.socia.ion studies should help to improve our understa.ding of ga.tric ca.cer etiology in order to d

关键词： La.in a.erica Ga.tric ca.cer Preca.cerous lesions Gene polymorphisms Single nucleotide polymorphisms

a. integra.ed a.sessment of a.group with complex systema.ics: the Iberoma.hrebia. liza.d genus Poda.cis (Squa.a.a. La.ertida.)

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Integra.ive Zoology 2008年第4期3卷 247-266页

作者： miguel a.Ca.RETERO CIBIO Reseach Center in Biodiversity and Genetic ResourcesCampus Agrário de Vair鉶4485-661VairaoPortugal

a.critica. review of the evolutiona.y biology of Iberia. a.d North a.rica. liza.d members of the genus Poda.cis(La.ertida.)ba.ed on phylogeny,phylogeogra.hy,morphometrics,beha.ior,ecology a.d physiology is *** Iberoma.hrebia. region is inha.ited by a. lea.t 12 different evolutiona.y linea.es tha. group into a.monophyl-etic cla.e(except Poda.cis mura.is).In contra.t to the current ta.onomy,the sa.icolous‘Poda.cis hispa.ica.is pa.a.hyletic with respect to Poda.cis boca.ei a.d Poda.cis ca.bonelli,two currently recognized *** in the phylogenetic tree a.e deep,resulting from old divergences,clea.ly preceding the ***,more recent ra.ge cha.ges a. a.result of gla.ia.ions a.e a.so *** most pla.sible evolutiona.y scena.io for this group indica.es both vica.ia.t a.d dispersa. *** pa.a.a.ry between linea.es is the rule,sympa.ry a.d even syntopy a.e frequent,but usua.ly between ground-dwelling a.d sa.icolous *** between forms with simila. ha.ita. use a.e ra.e a.d *** distinctiveness between linea.es ha. been demonstra.ed,indica.ing historica. ***,other cha.a.ters ha.e repea.edly evolved under simila. environmenta. pressures independently of the evolutiona.y *** sexua. dimorphism derives from sexua. selection a.d is a.ta.ned before sexua. ma.urity,a.though developmenta. restrictions *** between popu-la.ions is a.so importa.t a.d derives from loca. va.ia.ion in both na.ura.(ha.ita.,clima.e)a.d sexua.(density)selective *** for short-term cha.ges ha. a.rea.y been found,pa.ticula.ly in insula. *** isola.ion between syntopic forms a.d pa.tner recognition a.e ba.ed on ma.e–ma.e competition a.d on visua. a.d chemica. recognition of fema.es by conspecific *** this a.cient diversifica.ion,most forms ma.nta.n a.degree of reproductive *** ma. occur,but is limited,a.d there is evidence of selection

关键词： Morphometrics Mediterra.ea. ba.in phylogeny Poda.cis reproductive isola.ion specia.ion.

a. a.proa.h of the interna. friction-dependent tempera.ure cha.ges for conventiona. a.d pure biogenic lubrica.ing grea.es

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Friction 2024年第4期12卷 780-795页

作者： Leif a.ME Erik KUHN miguelÁngel DELGa.O Depa.tment of Mecha.ica. Engineering a.d Production Ma.a.ement Hamburg University of Applied SciencesHamburg 20099Germany Depa.tment of Chemica. Engineering Research in Product Technology and Chemical Processes(Pro2TecS)University of HuelvaHuelva 21071Spain

This work investiga.ed the tempera.ure cha.ges inside the bulk of lubrica.ing grea.es under controlled high-shea. stress conditions(250-500 s-1).For this purpose,a.newly developed tempera.ure-mea.uring cell ca.led Ca.idus wa. successfully *** tempera.ure cha.ges(ΔT)ha.e been rela.ed to the grea.es'components(thickener,ba.e oil-type,a.d composition)a.d the structura. degra.a.ion of the lubrica.ing ***,a.theoretica. a.proa.h wa. proposed for ca.cula.ing the interna. tempera.ure cha.ge of lubrica.ing grea.es during shea. *** grea.es showed a. interna. tempera.ure profile cha.a.terised by a.sudden rise inΔT within the first 4 h from sta.ting the test a.d subsequentΔT deca. until it rea.hes the stea.y sta.e ***,it wa. found tha. grea.es C1 a.d C5,formula.ed with lithium a.d ca.cium soa.,respectively,with different soa. content(16.1 wt%a.d 9.7 wt%,respectively),but the sa.e ba.e ca.tor oil,showed the highest va.ue of the ma.imumΔT,c.a.3.2 K,a.d the most dra.tic drop ofΔ*** grea.es showed both the highest specific densities a.d hea. *** a.dition,they showed the lowest ra.io of expended energies(Rtee),which mea.s more structura. degra.a.ion in the stressed *** the contra.y,the grea.e C3,with 13 wt%of Li-soa. but the lowest ba.e oil's viscosity,showed the lowest ma.imumΔT a.d the tempera.ure profile wa. cha.a.terised by a.modera.e va.ia.ion ofΔT a.ong the *** biogenic grea.e B3 developed a.low-tempera.ure cha.ge in the group of pure bio-genic grea.es close to grea.e C3.

关键词： shea.-induced structura. degra.a.ion rheology tempera.ure mea.urements lubrica.ing grea.es density lubrica.ing grea.es specific hea. ca.a.ities

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Ca.sule endoscopy

World Journa. of Ga.troenterology 2009年第13期15卷 1584-1586页

作者： miguel Muoz-Na.a. Ga.troenterology Depa.tment University Clinic of Navarra

Ca.sule endoscopy(CE) is a.simple,sa.e,non-inva.ive,relia.le technique,well a.cepted a.d tolera.ed by the pa.ients,which a.lows complete explora.ion of the sma.l *** a.vent of CE in 2000 ha. dra.a.ica.ly cha.ged the dia.nosis a.d ma.a.ement of ma.y disea.es of the sma.l intestine,such a. obscure ga.trointestina. bleeding,Crohn's disea.e,sma.l bowel tumors,polyposis syndromes,*** ha. become the gold sta.da.d for the dia.nosis of most disea.es of the sma.l *** this technique ha. a.so been used for esopha.ea. a.d colonic disea.es.

关键词： Ca.sule endoscopy Sma.l intestine Ga.trointestina. hemorrha.e Crohn's disea.e Ga.tro-intestina. neopla.ms Intestina. polyposis

Bra.n-ma.hine-bra.n interfa.es a. the founda.ion for the next genera.ion of neuroprostheses

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Na.iona. Science Review 2022年第10期9卷 8-10页

作者： miguel a.L.Nicolelis Depa.tment of Neurobiology Duke University Interna.iona. Institute of Neuroscience Edmond a.d Lily Sa.ra

Ba.k in 2011,my la.ora.ory a. the Duke University Center for Neuroengineering proposed a.new va.ia.ion on the a.rea.y-cla.sic pa.a.igm known a. bra.n-ma.hine interfa.es (BMIs)[1].In a.series of experiments [2],we showed tha. monkeys could not only lea.n to employ electrica. signa.s from la.ge neurona. ensembles (300-700 neurons)loca.ed in the prima.y motor cortex(M1) to control the movements of a. a.a.a. a.m a.d ha.d—*** a.typica. BMI pa.a.igm—but tha. they could a.so interpret in rea. time,strea.s of electrica. signa.s delivered directly to their prima.y soma.osensory cortex (S1) via.cortica. *** stra.egy wa. crea.ed to a.low these monkeys to perform a.ta.tile discrimina.ion ta.k,without a.y interference from their physica. ***,instea. of using their rea. finger tips to perform such a.ta.k,this a.proa.h a.lowed our monkeys to use their bra.n a.tivity to directly control the movements of’virtua. finger tips to sca. the texture of a.series of virtua. *** receiving,via.cortica. microstimula.ion,electrica. signa.s directly into their S1 tha. were proportiona. to the virtua. surfa.e textures of these objects,the monkeys lea.ned to quickly select the correct object tha. they needed to identify to receive a.***,

关键词：

Dyna.ic Insta.ility of Stra.ght Ba.s Subjected to Impulsive a.ia. Loa.s Using the DEM

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Computer Modeling in Engineering & Sciences 2015年第2期104卷 87-104页

作者： Leticia.Fleck Fa.el miguel Lea.dro Fleck Fa.el miguel Joa. Ka.inski Jr. Depa.tment of Mecha.ica. Engineering UFRGSPorto AlegreRSBrazil Depa.tment of Civil Engineering UFSCFlorianopolisSCBrazil Depa.tment of Structures a.d Civil Construction UFSMSanta MariaRSBrazil

Since the ha.f of the XX century,a.tention wa. given to the insta.ility of structures under pa.a.etric excita.ion,especia.ly under periodic *** the other ha.d,the insta.ility of ba.s subjected to a.ia. loa.s of impulsive type ha. been little studied,in spite of the pra.tica. importa.ce of the ***,in Engineering Design it is frequently supposed,without tests or a.ditiona. verifica.ions,tha. a. a.ia. loa. of short dura.ion ca. exceed the Euler critica. loa. of the ba. without inducing da.a.e in the *** this context,this pa.er proposes the use of the truss-like Discrete Element Method(DEM)for determining the dyna.ic response of ela.tic stra.ght ba.s subjected to a.ia. loa.s defined by pulses of short *** proposed a.proa.h a.lows the considera.ion of initia. imperfections,a. well a. la.ge displa.ements a.d other non-linea. *** influence of the pulse dura.ion a.d other effects in the response of the ba. a.e a.so ***,the performa.ce of the proposed methodology is verified in sta.ic a.d dyna.ic insta.ility problems of homogeneous ba.s without geometrica. imperfections,by compa.ing the DEM results with a.a.ytica. solutions a.a.la.le in the *** tha.,the DEM is employed to a.a.yze more complex ca.es,including ba.s with initia. imperfections a.d non-homogeneous ba.s,in which ma.eria. properties,a. Young’s modulus a.d ma.s density,a.e a.sumed to be correla.ed Ga.ssia. ra.dom *** proposed methodology ha. proven to be a.useful a.d ea.y tool for a.a.ysis of dyna.ic insta.ility of ba.s a.d could therefore be used by designers for estima.ing the dyna.ic buckling loa..

关键词： Dyna.ic Insta.ility Critica. Buckling Loa. Discrete Element Method Impulsive Loa. Stocha.tic Fields Mesh Imperfections

The Stra.berry Fruit Fra.a.a.lergen Functions in Fla.onoid Biosynthesis

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Molecula. Pla.t 2010年第1期3卷 113-124页

作者： Cristina.Munoz Thoma. Hoffma.n Nieves Medina.Escoba. Felix Ludema.n miguel a. Botella.Victoria.o Va.puesta.Wilfried Schwa. Depa.ta.ento de Biologia.Molecula. y Bioquimica Universidad de Malaga 29071 Malaga Spain Biomolecula. Food Technology Technische Universit~t M0nchen Hochfeldweg 1 85354 Freising Germany

The stra.berry Fra.a.I a.lergen is a.homolog of the ma.or birch pollen a.lergen Bet v 1. It is synthesized by red ripe fruits of Fra.a.ia.x a.a.a.sa.while white fruits of a.muta.t genotype, which is known to be tolera.ed by individua.s a.fected by a.lergy, a.e devoid of it. Proteomic a.a.yses ha.e shown tha. Fra.a.1 is down-regula.ed in the tolera.ed white- fruited genotype a.ong with enzymes of the a.thocya.in pigment pa.hwa.. In this study, we report the spa.ia. a.d tem- pora. expression of three Fra.a.genes tha. encode different isoforms, a.d the tra.sient RNa.-media.ed silencing of the Fra.a.genes in stra.berry fruits of the red-fruited cultiva. Elsa.ta.with a. ihpRNa.construct. a. a.consequence of reduced levels of Fra.a.mRNa., fruits were obta.ned tha. produced significa.tly decrea.ed levels of a.thocya.ins a.d upstrea. meta.olites. This effect is consistent with the pa.a.lel down-regula.ion of the phenyla.a.ine a.monia.lya.e （Fa.a.） a.d to a.lesser extent of the cha.cone syntha.e （Fa.HS） tra.script levels a.so found in these fruits. In na.ura.ly occurring white- fruited genotypes of F. chiloensis a.d F. vesca. Fra.a.tra.script levels a.e higher tha. those of the red-fruited va.ieties, likely to compensa.e for the low expression levels of Fa.a. a.d Fa.HS in these muta.t genotypes. The results demonstra.e tha. Fra.a.expression is directly linked to fla.onoid biosynthesis a.d show tha. the Fra.a.a.lergen ha. a. essentia. biologica. function in pigment forma.ion in stra.berry fruit.

关键词： Fra.a.ia fla.onoid a.thocya.in phenylpropa.oid a.lergen pa.hogenesis-rela.ed proteins.

Development a.d cha.a.teriza.ion of whey protein films incorpora.ed with ta.bush polyphenols a.d ca.delilla.wa.

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Food Bioscience 2022年第1期45卷 1-7页

作者： Olga.B.a.va.ez-Perez Ja.eth M.Ventura.Sobrevilla.Cristia. Torres-Leon Romeo Roja.-Molina.Ra.l Rodríguez-herrera miguel a.a.uila.-Gonza.ez Cristoba. N.a.uila. Bioprocesses a.d Bioproducts Resea.ch Group Food Research DepartmentSchool of ChemistryUniversidad Autonoma de Coahuila25280SaltilloCoahuilaMexico School of Hea.th Sciences Universidad Autonoma de Coahuila26090Piedras NegrasCoahuilaMexico School of a.ronomy Research Center and Development for Food IndustryUniversidad Autonoma de Nuevo Leon6050General EscobedoNuevo LeonMexico Center for Resea.ch a.d a.va.ced Studies of the Na.iona. Polytechnique Institute Parque Industrial Saltillo-Ramos ArizpeCoahuilaMexico

Edible films were prepa.ed with whey protein incorpora.ing ca.delilla.wa.,a.d glycerol in a.ueous *** polyphenols were a.ded a. bioa.tive *** optimiza.ion ba.ed on the wa.er va.or permea.ility(WVP)of the formula.ion wa. performed using a.Box-Behnken *** films were cha.a.terized by the determina.ion of WVP,moisture,solubility,color,a.tioxida.t a.d a.tifunga. *** electron microscopy(SEM)wa. a.so performed to observe the surfa.e a.d cross-section *** lowest permea.ility va.ues were found with concentra.ions of 1.27,0.3 a.d 0.5% of protein,wa. a.d glycerol *** wa. proved tha. the a.dition of polyphenols into films ca.ses a.significa.t effect only on solubility a.d tra.spa.ency *** films ha.e suita.le properties a. a.ba.rier for the goods they could be a.plied *** is proposed for use in foods such a. fresh or minima.ly processed fruits a.d vegeta.les.

关键词： Edible films Whey protein Shelf life Ca.delilla.wa. Euphorbia.a.tisyphilitica Fluorensia.cernua.polyphenols