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Degradation of ^(14)C-glyphosate and aminomethylphosphonic acid (AMPA) in three agricultural soils

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Journal of Environmental Sciences 2010年第9期22卷 1374-1380页

作者： Abdul Jabbar Al-Rajab michel Schiavon Laboratory of Soil and Environmental Sciences 54505 Vandoeuvre-lès-Nancy Cedex France Agriculture and Agri-Food Canada London Ontario N5V 4T3 Canada

Glyphosate （N-phosphonomethyl glycine） is the most used herbicide worldwide. The degradation of ^14C-labeled glyphosate was studied under controlled laboratory conditions in three different agricultural soils： a silt clay loam, a clay loam and a sandy loam soil. The kinetic and intensity of glyphosate degradation varied considerably over time within the same soil and among different types of soil. Our results demonstrated that the mineralization rate of glyphosate was high at the beginning of incubation and then decreased with time until the end of the experiment. The same kinetic was observed for the water extractable residues. The degradation of glyphosate was rapid in the soil with low adsorption capacity （clay loam soil） with a short half-life of 4 days. However, the persistence of glyphosate in high adsorption capacity soils increased, with half-live of 19 days for silt clay loam soil and 14.5 days for sandy loam soil. HPLC analyses showed that the main metabolite of glyphosate, arninomethylphosphonic acid （AMPA） was detected after three days of incubation in the extracts of all three soils. Our results suggested that the possibility of contamination of groundwater by glyphosate was high on a long-term period in soils with high adsorption capacity and low degrading activities and/or acid similar to sandy loam soil. This risk might be faster but less sustainable in soil with low adsorption capacity and high degrading activity like the clay loam soil. However, the release of non-extractable residues may increase the risk of contamination of groundwater regardless of the type of soil.

关键词： glyphosate aminomethylphosphonic acid (AMPA) mineralization degradation soil

Arabic (Egyptian) Vocabulary Builder+ (Learn Arabic with the michel Thomas Method) (Michael Thomas Method) Unabridged

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Endoscopic palliation of malignant biliary obstruction

2013年

作者： Jane Wightwick Mahmoud Gaafar michel Thomas

来源：畅想之星图书光盘版（南... 评论

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World Journal of Gastrointestinal Endoscopy 2022年第10期14卷 581-596页

作者： Andrew Canakis michel Kahaleh Department of Gastroenterology and Hepatology University of Maryland School of MedicineBaltimoreMD 21201United States Department of Gastroenterology and Hepatology Robert Wood Johnson Medical CenterNew BrunswickNJ 08901United States

Malignant biliary obstruction often presents with challenges requiring the endoscopist to assess the location of the lesion,the staging of the disease,the eventual resectability and patient preferences in term of biliary *** review will focus on the different modalities available in order to offer the most appropriate palliation,such as conventional endoscopic retrograde cholangiopancreatography,endoscopic ultrasound guided biliary drainage as well as ablative therapies including photodynamic therapy or radiofrequency ablation.

关键词： Biliary obstruction Endoscopic retrograde cholangiopancreatography Endoscopic ultrasonography Stenting Ablation therapy

Ochratoxin A induces abnormal tryptophan metabolism in the intestine and liver to activate AMPK signaling pathway

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Journal of Animal Science and Biotechnology 2023年第6期14卷 2674-2685页

作者： Weiqing Ma Yang Fu Shanshan Zhu Daiyang Xia Shuangshuang Zhai Deqin Xiao Yongwen Zhu michel Dione Lukuyu Ben Lin Yang Wence Wang Guangdong Provincial Key Laboratory of Animal Nutrition and Regulation College of Animal ScienceSouth China Agricultural UniversityGuangzhou 510642China. School of Marine Sciences Sun Yat-Sen Universityand Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China. College of Animal Science YangtzeUniversityJingzhou 434025China.4 College of Mathematics and Informatics South China Agricultural UniversityGuangzhou 510642China. Int Livestock Res Inst 24265 DakarSenegal. Int Livestock Res Inst Nairobi 00100Kenya

Background Ochratoxin A(OTA)is a mycotoxin widely present in raw food and feed materials and is mainly pro-duced by Aspergillus ochraceus and Penicillium *** previous study showed that OTA principally induces liver inflammation by causing intestinal flora disorder,especially Bacteroides plebeius(***)***,whether OTA or *** alteration leads to abnormal tryptophan-related metabolism in the intestine and liver is largely *** study aimed to elucidate the metabolic changes in the intestine and liver induced by OTA and the tryptophan-related metabolic pathway in the *** and methods A total of 30 healthy 1-day-old male Cherry Valley ducks were randomly divided into 2 *** control group was given 0.1 mol/L NaHCO3 solution,and the OTA group was given 235μg/kg body weight OTA for 14 consecutive *** metabolites were determined by intestinal chyme metabolomics and liver tryptophan-targeted ***-related signaling pathway factors were analyzed by Western blot-ting and mRNA *** Metabolomic analysis of the intestinal chyme showed that OTA treatment resulted in a decrease in intesti-nal nicotinuric acid levels,the downstream product of tryptophan metabolism,which were significantly negatively correlated with *** *** contrast,OTA induced a significant increase in indole-3-acetamide levels,which were positively correlated with *** ***,OTA decreased the levels of ATP,NAD+and dipeptidase in the *** tryptophan metabolomics analysis showed that OTA inhibited the kynurenine metabolic pathway and reduced the levels of kynurenine,anthranilic acid and nicotinic ***,OTA increased the phosphorylation of AMPK protein and decreased the phosphorylation of mTOR *** OTA decreased the level of nicotinuric acid in the intestinal tract,which was negatively correlated with *** *** abnormal metabolism of try

关键词： AMPK Metabolomics Ochratoxin A Tryptophan metabolism

Worldwide trends in esophageal cancer survival,by sub-site,morphology,and sex:an analysis of 696,974 adults diagnosed in 60 countries during 2000-2014(CONCORD-3)

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Cancer Communications 2023年第9期43卷 963-980页

作者： Melissa Matz Mikhail Valkov Mario Šekerija Sabine Luttman Adele Caldarella michel P Coleman Claudia Allemani the CONCORD Working Group Cancer Survival Group Department of Non-Communicable Disease EpidemiologyLondon School of Hygiene and Tropical MedicineLondon WC1E 7HTGreater LondonUnited Kingdom Department of Radiology Radiotherapy and OncologyNorthern State Medical UniversityArkhangelskArkhangelsk OblastRussia Croatian National Cancer Registry Croatian Institute of Public HealthZagrebZagreb CountyCroatia Bremen Cancer Registry BremenBremenGermany Tuscany Cancer Registry Istituto per lo studio e la prevenzione oncologicaFlorenceTuscanyItaly Cancer Division University College London Hospitals NHS Foundation TrustLondon NW1 2BUGreater LondonUnited Kingdom Members listed at the end of the article

Background Esophageal cancer survival is poor worldwide,though there is some *** in the distribution of anatomical sub-site and morphological sub-type may help explain international differences in survival for all esophageal cancers *** estimated survival by anatomic sub-site and morphological sub-type to understand further the impact of topography and morphology on international comparisons of esophageal cancer *** We estimated age-standardized one-year and five-year net survival among adults(15-99 years)diagnosed with esophageal cancer in each of 60 participating countries to monitor survival trends by calendar period of diagnosis(2000-2004,2005-2009,2010-2014),sub-site,morphology,and *** For adults diagnosed during 2010-2014,tumors in the lower third of the esophagus were the most common,followed by tumors of overlapping sub-site and sub-site not otherwise *** proportion of squamous cell carcinomas diagnosed during 2010-2014 was generally higher in Asian countries(50%-90%),while adenocarcinomas were more common in Europe,North America and Oceania(50%-60%).From 2000-2004 to 2010-2014,the proportion of squamous cell carcinoma generally decreased,and the proportion of adenocarcinoma *** time,there were few improvements in age-standardized five-year survival for each ***-standardized one-year survival was highest in Japan for both squamous cell carcinoma(67.7%)and adenocarcinoma(69.0%),ranging between 20%-60%in most other ***-standardized five-year survival from squamous cell carcinoma and adenocarcinoma was similar for most countries included,around 15%-20%for adults diagnosed during 2010-2014,though international variation was wider for squamous cell *** most countries,survival for both squamous cell carcinoma and adenocarcinoma increased by less than 5%between 2000-2004 and *** Esophageal cancer survival remains poor in many *** distributions

关键词： Cancer esophagus morphology survival topography trends

On the Equation n1n2= n3n4 Restricted to Factor Closed Sets

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Acta Mathematica Sinica,English Series 2018年第10期34卷 1517-1530页

作者： San Ying SHI michel WEBER School of Mathematics Hefei University of Technology Hefei 230009 P. R. China IRMA UMR 7501 7 rue Rend Descartes 67084 Strasbourg Cedex France

We study the number of solutions N（B,F） of the diophantine equation n1n2 = n3n4,where 1 ≤ n1≤B, 1≤ n3 ≤B, n2, n4 ∈ F and F C [1, B] is a factor closed set. We study more particularly the case when F = {m = p1^... 详细信息

关键词： Diophantine equation arithmetical functions factor closed set

The Gamow shell model with realistic interactions:a theoretical framework for ab initio nuclear structure at drip-lines

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Communications in Theoretical Physics 2022年第9期74卷 284-298页

作者： Nicolas michel Jianguo Li Furong Xu CAS Key Laboratory of High Precision Nuclear Spectroscopy Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijingChina School of Physics and State Key Laboratory of Nuclear Physics and TechnologyPeking UniversityBeijing 100871China

Ab initio approaches are among the most advanced models to solve the nuclear many-body *** particular,the no-core-shell model and many-body perturbation theory have been recently extended to the Gamow shell model framework,where the harmonic oscillator basis is replaced by a basis bearing bound,resonance and scattering states,*** Berggren *** continuum coupling is included at basis level and as configuration mixing takes care of internucleon correlations,halo and resonance nuclei can be properly described with the Gamow shell *** development of the no-core Gamow shell model and the introduction of the■-box method in the Gamow shell model,as well as their first ab initio applications,will be reviewed in this *** compared to models using harmonic oscillator bases will be shortly *** current power and limitations of ab initio Gamow shell model will also be discussed,as well as its potential for future applications.

关键词： binding energy lifetimes nucleon-nucleon interactions shell model continuum coupling

Subwavelength hybrid plasmonic structures for nonlinear nanophotonics

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Light(Science & Applications) 2021年第3期10卷 307-309页

作者： Ann-Katrin U.michel Optical Materials Engineering Laboratory Department of Mechanical and Process EngineeringETH ZurichZurichSwitzerland

Plasmonic structures made of a semiconductor-insulator-metal hybrid provide efficient routes for second-harmonic and sum-frequency generation in sub-micrometer structures,which ultimately may boost on-chip integrated ... 详细信息

关键词： structures nonlinear plasmon

Fruit availability, frugivore satiation and seed removal in 2 primate-dispersed tree species

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Integrative Zoology 2011年第3期6卷 178-194页

作者： Sandra RATIARISON Pierre-michel FORGET Department of Ecology and Management of Biodiversity Museum of Natural History Museum(MNHN)BrunoyFrance and oological Society of London LibrevilleGabon

During a mast-fruiting event we investigated spatial variability in fruit availability,consumption,and seed removal at two sympatric tree species,Manilkara bidentata and ***(Sapotaceae)at Nouragues Natural Reserve,French *** addressed the question of how Manilkara density and fruits at the community level might be major causes of variability in feeding assemblages between tree *** thus explored how the frugivore assemblages differed between forest patches with contrasting relative Manilkara density and fruiting *** the daytime,Alouatta seniculus was more often observed in *** crowns at Petit Plateau(PP)with the greatest density of Manilkara *** the lowest fruit diversity and availability,whereas Cebus apella and Saguinus midas were more often observed in *** crowns at both Grand Plateau(GP),with a lowest density of *** and overall greater fruit supply,and ***,nearly 53%and 15%of the *** seed crop at GP and PP,respectively,and about 47%of the *** seed crop were removed,otherwise either spit out or defecated beneath trees,or dropped in ***-bodied primates concentrated fallen seeds beneath parent trees while large-bodied primate species removed and dispersed more seeds away from ***,among the latter,satiated *** wasted seeds under conspecific trees at *** in feeding assemblages,seed removal rates and fates possibly reflected interactions with extra-generic fruit species at the community level,according to feeding choice,habitat preferences and ranging patterns of primate species.

关键词： frugivores masting primates satiation seed dispersal