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Therapeutic role of Ricinus communis L. and its bioactive compounds in disease prevention and treatment

Asian Pacific journal of Tropical Medicine 2018年第3期11卷 177-185页

作者： Waseem Mohammed Abdul Nahid H.Hajrah jamal S.M.sabir Saleh M.Al-Garni meshaal j.sabir Saleh A.Kabli Kulvinder Singh Saini Roop Singh Bora Biotechnology Research Group Department of Biological SciencesFaculty of ScienceKing Abdulaziz University Department of Biological Sciences Faculty of ScienceKing Abdulaziz University Department of Biotechnology Eternal University

Ricinus communis L.(R. communis), commonly known as castor oil plant, is used as a traditional natural remedy or folkloric herb for the control and treatment of a wide range of diseases around the globe. Various studies have revealed the presence of diverse phytochemicals such as ***, terpenes, saponins,phenolic compounds such as kaempferol, gallic acid, ricin, rutin, lupeol, ricinoleic acid, pinene, thujone and gentisic *** phytochemicals have been responsible for pharmacological and therapeutic effects,including anticancer, antimicrobial, insecticidal, antioxidant, anti-diabetic, antinociceptive,anti-inflammatory. bone regenerative, analgesic, and anticonvulsant activity. R. communis harbours phytochemicals which have been shown to target peroxisome proliferator activated receptor(PPAR), nuclear factor NF-κ-B, cytochrome p450, P38 mitogen-activated protein kinases kinase(p38 MAPK), tumor protein P53, B-cell lymphoma-extra-large(Bcl-xL) and vascular endothelial growth factor receptor-2(VEGFR-2). Considering its wide variety of phytochemicals, its pharmacological activity and the subsequent clinical trials, R. communis could be a good candidate for discovering novel complementary drugs. Further experimental and advanced clinical studies are required to explore the pharmaceutical, beneficial therapeutic and safety prospects of R. communis with its phytochemicals as a herbal and complementary medicine for combating various diseases and disorders.

关键词： Ricinus communis Bioactive compounds Ethnomedicine Molecular targets Anti-cancer Pharmacology

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Photon orbits and phase transition for Letelier AdS black holes immersed in perfect fluid dark matter

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Chinese Physics C 2024年第6期48卷 247-259页

作者： Ashima Sood Md sabir Ali j.K.Singh Sushant G.Ghosh Department of Mathematics Netaji Subhas University of TechnologyNew Delhi-110078India Centre for Theoretical Physics Jamia Millia IslamiaNew Delhi 110025India Department of Physics Mahishadal Raj CollegePurba MedinipurWest Bengal721628India Institute of Theoretical Physics&Research Center of Gravitation Lanzhou UniversityLanzhou 730000China Key Laboratory of Quantum Theory and Applications of MoE Lanzhou UniversityLanzhou 730000China Lanzhou Center for Theoretical Physics&Key Laboratory of Theoretical Physics of Gansu Province Lanzhou UniversityLanzhou 730000China Astrophysics and Cosmology Research Unit School of MathematicsStatistics and Computer ScienceUniversity of KwaZulu-NatalPrivate Bag X54001Durban 4000South Africa

We obtain an exact solution for spherically symmetric Letelier AdS black holes immersed in perfect fluid dark matter(PFDM).Considering the cosmological constant as the positive pressure of the system and volume as its conjugate variable,we analyze the thermodynamics of our black holes in the extended phase *** to the background clouds of strings parameter(a)and the parameter endowed with PFDM(β),we analyze the Hawking temperature,entropy,and specific ***,we investigate the relationship between the photon sphere radius and phase transition for the Letelier AdS black holes immersed in *** the analysis,with a particular condition,non-monotonic behaviors are found between the photon sphere radius,impact parameter,PFDM parameter,temperature,and *** can regard the changes in both the photon sphere radius and impact parameter before and after phase transition as the order parameter;their critical exponents near the critical point are equal to the same value,1/2,similar to that in ordinary thermal *** indicates that a universal relation of gravity may exist near the critical point for a black hole thermodynamic system.

关键词： AdS black holes perfect fluid dark matter Letelier spacetime photon orbit extended phase space thermodynamics correlation of photon orbit and thermodynamics

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In-situ copolymerization of aniline with alkyl amine by APS:Kinetics and application

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Chinese Chemical Letters 2008年第11期19卷 1358-1362页

作者： M.Rashid Shams Qamar Usmani Suhail sabir Polymer Research Laboratory Department of ChemistryAligarh Muslim UniversityAligarh 202002India

The kinetic study of in-situ eopolymerization of aniline with o- and p-methylaniline by ammonium persulfate （APS） has been carried out. UV-vis spectroscopic method was used to investigate the course of copolymerization. Structural characterization was studied by PT-IR spectral analysis. The electronic spectra of the copolymers poly（aniline-co-p-toluidine） and poly（aniline-co-o- toluidine） show blue shift. The shift has been observed in the bands corresponding to π→π^＊ transition as well as in the exciton transition. The increase in absorbance recorded during the reaction for different concentration of aniline, o- and p-toluidine at various intervals of time of polymerization reaction indicates a growth in the polymer formation. The resulting first-order rate constant was used to calculate the rate of copolymer formation using the rate equation -d[A]/dt = kc^n.

关键词： Copolymerization Corrosion inhibition Electronic and vibrational spectra

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Effective desalination and anti-biofouling performance via surface immobilized MWCNTs on RO membrane

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Chinese journal of Chemical Engineering 2023年第4期56卷 33-45页

作者： Aneela sabir Wail Falath Muhammad Shafiq Nafisa Gull Maria Wasim Karl Ijacob School of Materials Science and Engineering Georgia Institute of TechnologyAtlantaGAUSA G.W.Woodruff School of Mechanical Engineering Georgia Institute of TechnologyAtlantaGAUSA Institute of Polymer of Textile Engineering University of the PunjabLahore 54590Pakistan Department of Mechanical Engineering King Fahd University of Petroleum and MineralsDhahran 31261Saudi Arabia

Desalination is considered a viable method to overcome the issue of water scarcity either from waste water or seawater. For this purpose, this study employed a facile approach to develop surface immobilized oxidized-MWCNTs(o-MWCNTs) onto crosslinked polyvinyl alcohol(PVA) membrane. Firstly, modified polysulphone substrate was synthesized on to which crosslinked PVA layer was spread onto it. PVA layer act as active layer for surface immobilization of o-MWCNTs in varying concentration. The functional group analysis, morphology and roughness of membranes surface was conducted out using FTIR, SEM and AFM respectively. The results showed that modified membranes, immobilized o-MWCNTs enhanced the salt rejection(Na_(2)SO_(4)) upto 99.8%. After contacting with Escherichia coli and Staphylococcus aureus for 2.5 h the bacteria mortalities of the fabricated membrane could reach 96.9%. Furthermore, the antibiofouling tests showed that OP-MWCNTs(1-5) modified membranes have higher anti-biofouling property than the control membrane.

关键词： Surface immobilized Reverse osmosis Multi walled carbon nanotubes Nanomaterials

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Hydromagnetic peristaltic transport of copper-water nanofluid with temperature-dependent effective viscosity

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Particuology 2016年第4期14卷 133-140页

作者： Fahad M. Abbasi Tasawar Hayat sabir A. Shehzad Fuad Alsaadi Naif Altoaibi Department of Mathematics COMSATS Institute of lnformation Technology Islamabad 44000 Pakistan Department of Mathematics Quaid-l-Azam University 45320 Islamabad 44000 Pakistan Department of Electrical and Computer Engineering Faculty of Engineering King Abdulaziz University Jeddah Saudi Arabia Department of Mathematics COMSATS Institute of Information Technology Sahiwal Pakistan

The unique chemical mechanical, and thermodynamic properties of nanofluids make them a subject of great interest for scientists from all domains. Such fluids are of particular significance in biomedical engineering owing to their vast and novel applications in modern drug delivery systems; for example, mixed convective peristaltic flow of water-based nanofluids under the influence of an externally applied magnetic field is of particular significance. Hence, a lot of research has focused on peristalsis in the presence of velocity and thermal slip effects. An empirical relation for the effective viscosity of the nanofluid is proposed here for the first time. The viscosity of the nanofluid varies with temperature and nanoparticle volume fraction. Numerical simulation of the resulting nonlinear system of equations is presented for different quantities of interest. The results indicate that the maximum velocity and temperature of the copper-water nanofluid increase for larger variable viscosity parameter. The pressure gradient in the wider part of the channel is also found to increase as a function of the variable viscosity parameter. The variable viscosity parameter also influences the size of the trapped bolus. An increase in the nanoparticle volume fraction reduces the reflux phenomenon in a peristaltic flow.

关键词： Temperature dependent effective viscosity Copper-water nanofluid Peristalsis Slip effect Magnetohydrodynamics

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Numerical investigations to design a novel model based on the fifth order system of Emden–Fowler equations

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Theoretical & Applied Mechanics Letters 2020年第5期10卷 333-342页

作者： Zulqurnain sabir Mehmet Giyas Sakar Manshuk Yeskindirova Onur Saldir Department of Mathematics and Statistics Hazara UniversityMansehraPakistan Department of Mathematics Faculty of SciencesYuzuncu Yil UniversityVanTurkey Department of Translation Theory and Practice L.N.Gumilyov Eurasian National UniversityKazakhstan

The aim of the present study is to design a new fifth order system of Emden–Fowler equations and related four types of the *** standard second order form of the Emden–Fowler has been used to obtain the new *** shape factor that appear more than one time discussed in detail for every case of the designed *** singularity atη=0 at one point or multiple points is also discussed at each type of the *** validation and correctness of the new designed model,one example of each type based on system of fifth order Emden–Fowler equations are provided and numerical solutions of the designed equations of each type have been obtained by using variational iteration *** comparison of the exact results and present numerical outcomes for solving one problem of each type is presented to check the accuracy of the designed model.

关键词： Fifth order Emden-Fowler system Multiple singularity Shape factor Numerical experimentations Variational iteration scheme

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Evaluation of ecosystem supply services and calculation of economic value in Kargil District

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Regional Sustainability 2022年第2期3卷 157-169页

作者： sabir HUSSAIN Sheenu SHARMA Anand Narain SINGH Soil Ecosystem and Restoration Ecology Lab Department of BotanyPanjab UniversityChandigarh160014India

Mountain ecosystem provides numerous vital ecosystem services(ESs)to the people residing within or near the mountains *** mountains provide services such as timber,fibre,fodder,fuelwood,medicine,aesthetic,recreation,ritual,and religion,and many other services that are vital for the maintenance of the *** mountains of Barsoo and Tai-Suru regions in Kargil District are much familiar for their ESs supply,and the residents have utilized these services for *** present study was focused on the provisioning *** used a random sample approach for household selection and data collection regarding the pre-prepared questionnaire;the number of households was obtained from government census *** primary ESs(identified by more than 40%of the respondents)were assessed through the direct market valuation *** direct market valuation method produced an overwhelming value,specifically for grazing and fodder services in both regions of the study *** showed that grazing service was valued at 482,346.43 USD/a for Barsoo region and 1,458,099.04 USD/a for Tai-Suru ***,fodder service of Barsoo and Tai-Suru regions corresponded to values of 69,833.61 and 110,886.06 USD/a,*** the other hand,food service of Barsoo and Tai-Suru regions was valued at 2601.04 and 2969.90 USD/a,respectively,and medicinal service was valued at 757.39 and 4430.94 USD/a in Barsoo and Tai-Suru regions,*** addition,the regions were economically backwards,and the resident’s survival and well-being relied on the mountain ***,it is not possible for the residents to pay services replacement costs if the services need to replace by other ***,such mountain ecosystem is highly prone to climate change and other human activities that would negatively impact the ecosystem ***,this study would be helpful for the policymakers of the region to draft any developmental plan/framework by integrating the value

关键词： Mountain ecosystem Ecosystem services Sustainability Livelihood Direct market valuation method Barsoo Tai-Suru

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Studies on the effects of pre-firing and sintering temperature on NSDC nanocomposite electrolytes

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Progress in Natural Science:Materials International 2022年第1期32卷 128-134页

作者： Saddam Hussain Yangping Li Fida Hussain Memon sabir Hussain Lei Li Khalid Hussain Thebo State Key Laboratory of Solidification Processing School of Materials Science and Engineering Northwestern Polytechnical University Department of Electrical Engineering Sukkur IBA University Department of Space Science University of the Punjab University of Chinese Academy of Sciences

Solid oxide fuel cells（SOFCs） technology, with fuel flexibility, is one of the most promising power generation technology. However, the high operating temperature of SOFCs has hindered their commercial applications. As a crucial requirement to enhance its performance, SOFCs electrolytes should operate at a low temperature. Carbonate/ceria composites are developed as electrolytes for low operating temperature SOFCs, and a better understanding of the mechanism of its ionic conductivity serves this purpose. In this work, ceria-carbonate composite electrolyte, Na;CO;/samarium doped ceria（NSDC） were synthesized by the co-precipitation *** synthesized electrolytes were characterized by X-ray diffraction（XRD）, scanning electron microscopy（SEM）,X-ray photoelectron spectroscopy（XPS）, and UV–Vis spectroscopy. The XRD and SEM results showed that the sintered NSDC nanocomposite comprised a single-phase dense electrolyte structure. The crystallite size of the NSDC nanocomposite was greatly affected by the different pre-firing temperatures and different sintering temperatures. Also, the ionic conductivity of the prepared NSDC nanocomposite electrolytes was strongly dependent on the pre-firing and sintering temperatures. The NSDC nanocomposite electrolytes were pre-fired at 950°C and650°C and sintered at 1200°C and 900°C respectively, had ionic conductivity in H;and air high as 0.36 S/cm and 0.3 S/cm.

关键词： Solid oxide fuel cell NDSC Composite Electrolyte Ionic conductivity

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High harmonic exploring on different materials in dynamic atomic force microscopy

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Science China(Technological Sciences) 2018年第3期61卷 446-452页

作者： ZHENG ZhiYue XU Rui YE ShiLi HUSSAIN sabir jI Wei CHENG Peng LI Yanjun SUGAWARA Yasuhiro CHENG ZhiHai CAS Center for Excellence in Nanoscience and Key Laboratory of Standardization and Measurement for Nanotechnology National Center for Nanoscience and Technology Beijing 100190 China Department of Physics Renmin University of China Beijing 100872 China The State Key Laboratory of Digital Manufacturing Equipment and Technology Department of Instrument Science and Technology School of Mechanical Science and Engineering Huazhong University of Science and Technology Wuhan 430074 China University of Chinese Academy of Sciences Belting 100049 China Asylum Research Santa Barbara 93117 USA Department of Applied Physics Graduate School of Engineering Osaka University Osaka 565-0871 Japan

In atomic force microscopy(AFM), high-frequency components consisted in dynamic tip-sample interaction have been recently demonstrated as a promising technique for exploring more extensive material properties. Here we present an exploratory study of high harmonic atomic force microscopy by force-spectroscopy and high harmonic imaging. Since these components are very weak compared to the fundamental response, we firstly designed a high harmonic cantilever by tuning the second order flexural resonance frequency to an integer 6 times of its fundamental mode(i.e. ω_2=6ω_1). Moreover, it is verified that high harmonic can discern extra features than topographies on different samples with amplitude/frequency modulation(AM/FM) dynamic AFM mode. In AM mode, the first resonance amplitude and 6 th harmonic amplitude were discussed. The 6 th harmonic is more sensitive than the first order response. In FM mode, it is noted that the decaying rate of the 6 th harmonic frequency is approximately 6 multiples to the slope of the fundamental frequency shift when the tip approaches to the surface of sample. This non-destructive method was also adopted to investigate the local interlayer coupling and intercalation in the two-dimensional graphene films tentatively.

关键词： high harmonic AFM high harmonic cantilever dynamic AFM

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Local electrical charac terization of t wo-dimensional mat erials with functional atomic force microscopy

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Frontiers of physics 2019年第3期14卷 85-105页

作者： sabir Hussain Kunqi Xu Shili Ye Le Lei Xinmeng Liu Rui Xu Liming Xie Zhihai Cheng CAS Key Laboratory of Standardization and Measurement for Nanotechnology CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 China Department of Physics and Beijing Key Laboratory of Optoelectronic Functional Materials & Micro-nano Devices Renmin University of China Beijing 100872 China University of Chinese Academy of Sciences Beijing 100049 China

Research about two-dimensional (2D) materials is growing exponentially across various scientific and engineering disciplines due to the wealth of unusual physical phenomena that occur when charge transport is confined to a plane. The applications of 2D materials are highly affected by the electrical properties of these mat erials, including curren t dist ribution, surface pot ential, dielectric response, conductivity, perm计tivity, and piezoelectric response. Hence, it is very crucial to characterize these properties at the nanoscale. The Atomic Force Microscopy (AFM)-based techniques are powerful tools that can simultaneously characterize morphology and electrical properties of 2D materials with high spatial resolution, thus being more and more extensively used in this research field. Here, the principles of these AFM techniques are reviewed in detail. After that, their representative applications are further demonstrated in the local characterization of various 2D materials? elcctrical properties.

关键词： advanced AFM techniques nanoscale characteTization electrical properties 2D materials

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