检索结果-南通市图书馆

Individualized elective irradiation of the clinically node-negative neck in definitive radiotherapy for head and neck squamous cell carcinoma

引用

Cancer Communications 2021年第4期41卷 303-315页

作者： Jia Kou Li Lin Cheng-Yang Jiao meng-qiu tian Guan-Qun Zhou Xue Jiang Jun Ma Zhen-Yu Qi Yao Lu Ying Sun Department of Radiation Oncology Sun Yat-sen University Cancer Center/State Key Laboratory of Oncology in South China/Collaborative Innovation Center for Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapyGuangzhouGuangdong 510060P.R.China Perception vision medical technology co.LTD GuangzhouGuangdong 510275P.R.China School of Data and Computer Science Sun Yat-sen UniversityGuangdong Province Key Laboratory of Computational ScienceGuangzhouGuangdong 510275P.R.China

Background:Oral cavity(OC),oropharyngeal(OP),hypopharyngeal(HP),and laryngeal(LA)squamous cell carcinoma(SCC)have a high incidence of regional lymph node metastasis(LNM).Elective irradiation for clinically node-negative neck is routinely administered to treat lymph nodes harboring occult ***,the optimal elective irradiation schemes are still *** this study,we aimed to establish individualized elective irradiation schemes for the ipsilateral and contralateral node-negative neck of these four types of ***:From July 2005 to December 2018,793 patients with OC-SCC,464 with OP-SCC,413 with HP-SCC,and 645 with LA-SCC were recruited *** on the actual incidence of LNM and the tumor characteristics,risk factors for contralateral LNM,as well as node level coverage schemes for elective irradiation,were determined using logistic regression ***,we developed a publicly available online tool to facilitate the widespread clinical use of these ***:For the ipsilateral node-negative neck,elective irradiation at levels Ⅰ-Ⅲ for OC-SCC and levels Ⅱ-Ⅳa for OP-,HP-and LA-SCC are generally *** addition,level Ⅶa should be included in patients with *** analyses revealed that posterior hypopharyngeal wall and post-cricoid region involvement were independently associated with level Ⅶa metastasis in HP-SCC(all P<0.05).For the contralateral node-negative neck,multivariate analyses revealed that ipsilateral N2b2-N3,tumors with body midline involvement,and degree of tumor invasion were the independent factors for contralateral LNM(all P<0.05).In patients who require contralateral neck irradiation,levels Ⅰ-Ⅱ are recommended for OC-SCC,and additional level Ⅲ is recommended for patients with ipsilateral N3 *** Ⅱ-Ⅲ are recommended for OP-,HP-,and LA-SCC,and additional level Ⅳa is recommended for patients with advanced T or ***,additional level Ⅶa

关键词： clinically node-negative neck elective irradiation head and neck squamous cell carcinoma individualization neck node level

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Dip2a regulates stress susceptibility in the basolateral amygdala

引用

Neural Regeneration Research 2025年第6期20卷 1735-1748页

作者： Jing Li Zixuan He Weitai Chai meng tian Huali Yu Xiaoxiao He Xiaojuan Zhu Key Laboratory of Molecular Epigenetics Ministry of Education Institute of Genetics and CytologyNortheast Normal UniversityChangchunJilin ProvinceChina

Dysregulation of neurotransmitter metabolism in the central nervous system contributes to mood disorders such as depression, anxiety, and post–traumatic stress disorder. Monoamines and amino acids are important types of neurotransmitters. Our previous results have shown that disco-interacting protein 2 homolog A(Dip2a) knockout mice exhibit brain development disorders and abnormal amino acid metabolism in serum. This suggests that DIP2A is involved in the metabolism of amino acid–associated neurotransmitters. Therefore, we performed targeted neurotransmitter metabolomics analysis and found that Dip2a deficiency caused abnormal metabolism of tryptophan and thyroxine in the basolateral amygdala and medial prefrontal cortex. In addition, acute restraint stress induced a decrease in 5-hydroxytryptamine in the basolateral amygdala. Additionally, Dip2a was abundantly expressed in excitatory neurons of the basolateral amygdala, and deletion of Dip2a in these neurons resulted in hopelessness-like behavior in the tail suspension test. Altogether, these findings demonstrate that DIP2A in the basolateral amygdala may be involved in the regulation of stress susceptibility. This provides critical evidence implicating a role of DIP2A in affective disorders.

关键词： 5-hydroxytryptamine acute restraint stress basolateral amygdala CaMKII neurons DIP2A metabolomics neurotransmitters principal component analysis stress susceptibility tryptophan

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pulp health and calcific healing of a complicated crown–root fracture with additional root fracture in a maxillary incisor: A case report

引用

World Journal of Clinical Cases 2025年第3期13卷 42-49页

作者： Na Li Yue-Yue Ren Ying Tang Qi Yang tian-tian meng Song Li Jing Zhang Stomatological Hospital and College Anhui Medical UniversityHefei 230032Anhui ProvinceChina Department of Endodontics The Affiliated Stomatological Hospital of Xuzhou Medical UniversityXuzhou 221000Jiangsu ProvinceChina

BACKGROUND Complicated crown–root fracture (CRF) involves severe injury to the crown, root,and pulp, and may be accompanied by multiple root fractures. The loss of a toothhas lifelong consequences for children and teenagers, but the maintenance of pulphealth and the calcific healing of multiple root fractures are rarely reported in *** SUMMARY This case reports healing of a permanent tooth with complicated crown–root andadditional root fractures, in which pulp health was maintained. A 10-year-old girlfell and fractured the root of her maxillary left central incisor at the cervical *** the coronal fragment was repositioned, the tooth was splinted until thetooth was no longer mobile, 2 years later. Eight years after treatment, the toothhas remained asymptomatic with vital pulp and localized gingival ***-beam computed tomography revealed not only calcified healing of the CRFbut also spontaneous healing in an additional undiagnosed root fracture. Thefracture line on the enamel could not be healed by hard tissue and formed agroove in the cervical crown. It was speculated that the groove was related to thelocalized gingival *** This case provides a clinical perspective of the treatment of a tooth with acomplicated CRF and an additional root fracture.

关键词： Complicated crown-root fracture Multiple root fracture Spontaneous healing Cone-beam computed tomography Long-term follow-up Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in ethnopharmacology,phytochemistry and pharmacology of Erigerontis Herba and its Chinese medicine prescriptions

引用

Traditional Medicine Research 2025年第1期10卷 44-61页

作者： Yang Zhou Yuan-Yan Huang Ding-Yue Shang Ying Chen meng tian Cheng-Yu Jin Xin Lu Bing-Chun Yan Han-Qing Pang Institute of Translational Medicine School of MedicineYangzhou UniversityYangzhou 225009China Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases Yangzhou UniversityYangzhou 225009China School of Medicine Nanjing University of Chinese MedicineNanjing 210023China State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources Guangxi Normal UniversityGuiling 541004China.

Erigerontis Herba(EH),the dried whole plant of Erigeron breviscapus,is well-known for circulating blood,activating meridians to alleviate pain,expelling wind,and clearing away *** has been extensively utilized in southern China for the treatment of stroke hemiplegia,chest stuffiness and pains,rheumatic arthralgia,headache,and *** review focuses on the botany,ethnopharmacology,phytochemistry,pharmacology and toxicity of EH and its related prescriptions to offer new insights for prospective research of *** information about EH was retrieved from ancient records and books,PubMed,China National Knowledge Infrastructure,Chinese Pharmacopoeia,Web of Science,Doctoral and Master’s Theses,and various electronic *** is a member of Compositae family and is mainly grown in southern *** Chinese medicine records that EH has the effects of circulating blood and removing blood stasis,expelling wind,and removing cold,as well as relieving rigidity of muscle and relieving *** now,nearly 200 ingredients have been characterized from EH,including flavonoids,caffeoyls,aromatic acids,coumarins,pentacyclic terpenoids,volatile oil and other *** extracts,EH related prescriptions(Dengzhan Xixin injection,Dengzhan Shengmai capsules,etc.)or compounds(scutellarin,scutellarein,etc.)possessed obvious therapeutic effects of ischemic stroke,cerebral hemorrhage,myocardial infarction,Alzheimer’s disease,diabetes and its complications,gastric cancer,bone,and joint degenerative ***,the major active compound of EH,has been used as a quality *** no obvious toxicity of EH has been *** to its traditional applications,ethnopharmacology,phytochemistry,pharmacology,and toxicity,EH was applied as a valuable herb for clinical application in food and medicine *** several compounds have been shown to possess diverse biological activities,the underlying mechanisms of their actions remain *** fully exploi

关键词： Erigeron breviscapus traditional applications ethnopharmacology phytochemistry pharmacology

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

水轮发电机组运行温度预测

引用

通信电源技术 2017年第4期34卷 144-145,147页

作者：张智陈博施梦奇邱天怡贺松祥高适梯级水电站运行与控制湖北省重点实验室(三峡大学) 湖北宜昌443002 三峡大学电气与新能源学院湖北宜昌443002 黄冈供电公司检修分公司湖北黄冈438000 东源电力有限公司瑞华分公司湖北黄冈438000

随着水轮机组容量不断增大,为保证水电站安全运行,文章对水轮发电机组正常运行的温度进行研究。由于发电机组内部结构复杂导致其温度不易直接测量。通过对水轮机蜗壳进口处的水温和尾水管处出口的水温进行监测,建立灰色神经网络预测模型... 详细信息

随着水轮机组容量不断增大,为保证水电站安全运行,文章对水轮发电机组正常运行的温度进行研究。由于发电机组内部结构复杂导致其温度不易直接测量。通过对水轮机蜗壳进口处的水温和尾水管处出口的水温进行监测,建立灰色神经网络预测模型,并与灰色预测和神经网络预测进行对比分析。实测结果表明,该方法达到较好数据处理和预测结果。

关键词：水轮发电机组温度预测灰色神经网络数据预测

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Management and Reconfiguration of a Radiology Department under the Threat of Coronavirus Disease 2019:Experience from Wuhan

引用

Current Medical Science 2020年第4期40卷 608-613页

作者： meng tian Cong-cong LIU Lu LONG qiu-xia WANG Department of Radiology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430000China Department of Epidemiology and Biostatistics West China School of Public HealthSichuan UniversityChengdu 610000China

Summary:The corona virus disease 2019(COVID-19)is an emerging respiratory infectious disease caused by SARS-CoV-2,which first occurred in December 2019 in Wuhan,*** days,in China,chest CT is used for diagnosis of COVID-19,as an important complement to the reverse-transcription polymerase chain reaction(RT-PCR)*** of contacting with a large number of suspected or probable cases closely during chest CT examination,radiographers are easily infected with *** article included the rearrangement of CT examination room in fever clinic,the rearrangement of human resources in radiology department,and the drafting of new operating procedures for radiologists who carry out CT examination on COVID-19 *** article also introduced the emergency management procedures of the department of radiology during the outbreak,and the experience of infection prevention for the staff of the department of radiology.

关键词： COVID-19 management reconfiguration radiology department

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Modeling the Wettability of Microstructured Hydrophobic Surface Using Multiple-relaxation-time Lattice Boltzmann Method

引用

Journal of Bionic Engineering 2022年第5期19卷 1460-1471页

作者： Lei tian Liuchao qiu College of Water Resources and Civil Engineering China Agricultural UniversityBeijing 100083China

Wetting properties are significant for a hydrophobic surface and normally characterized by the equilibrium contact *** this manuscript,a mesoscopic method based on multiphase multiple-relaxation-time Lattice Boltzmann method has been presented and applied to simulate the contact angle at three-phase interfaces of a solid surface with micro-pillar *** influence of different parameters including pillar height,pillar width,inter-pillar spacing,intrinsic contact angle and the volume of the liquid drop on the equilibrium contact angle has been comprehensively *** effect of geometry parameters of the micro-pillar structure on the wetting transition from Cassie–Baxter state to Wenzel state has also been *** results indicate that when the inter-pillar spacing is less than a certain value or the pillar height is greater than a certain value,the contact form between the droplet and the surface satisfies the Cassie–Baxter *** the contact form satisfies the Cassie–Baxter state,the contact angle gradually increases with the increase of the inter-pillar spacing;the contact angle does not change significantly with the pillar height;the contact angle gradually decreases and approaches the intrinsic contact angle with the pillar width ***,the contact angle increases with the increase of the intrinsic contact angle,and the contact angle is not sensitive to the change of droplet volume when the droplet volume is between 0.5 and10μl.

关键词： Bioinspired hydrophobic surface Wettability Cassie-Baxter state Wenzel state Lattice Boltzmann method Mesoscale simulation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The 2-axis stress component decoupling of {100} c-Si by using oblique backscattering micro-Raman spectroscopy

引用

Science China(Physics,Mechanics & Astronomy) 2020年第9期63卷 51-57页

作者： DongHui Fu XiaoYong He LuLu Ma HuaDan Xing tian meng Ying Chang Wei qiu tianjin Key Laboratory of Modern Engineering Mechanics Department of MechanicsTianjin UniversityTianjin 300350China Department of Mechanical Engineering Lamar UniversityBeaumont TX 77710USA Department of Electrical and Computer Engineering University of DelawareNewark DE 19711USA

With the application of strain engineering in microelectronics,complex stress states are introduced into advanced semiconductor ***,there is still a lack of effective metrology for the decoupling analysis of the complex stress states in semiconductor *** paper presents an investigation on the 2-axis stress component decoupling of{100}monocrystalline silicon(c-Si)by using oblique backscattering micro-Raman spectroscopy.A spectral-mechanical model was established,and two practicable methods for actual stress decoupling analyses were *** verification experiments demonstrated the correctness and applicability of the methods proposed in this paper.

关键词： {100}c-Si stress component decoupling oblique backscattering micro-Raman spectroscopy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hybrid data-driven framework for shale gas production performance analysis via game theory, machine learning, and optimization approaches

引用

Petroleum Science 2023年第1期20卷 277-294页

作者： Jin meng Yu-Jie Zhou tian-Rui Ye Yi-tian Xiao Ya-qiu Lu Ai-Wei Zheng Bang Liang Petroleum Exploration and Production Research Institute SINOPECBeijing100083PR China Jianghan Oilfield Company Research Institute of Exploration and DevelopmentSINOPECWuhan430223HubeiPR China

A comprehensive and precise analysis of shale gas production performance is crucial for evaluating resource potential,designing a field development plan,and making investment ***,quantitative analysis can be challenging because production performance is dominated by the complex interaction among a series of geological and engineering *** fact,each factor can be viewed as a player who makes cooperative contributions to the production payoff within the constraints of physical laws and *** by the idea,we propose a hybrid data-driven analysis framework in this study,where the contributions of dominant factors are quantitatively evaluated,the productions are precisely forecasted,and the development optimization suggestions are comprehensively *** specifically,game theory and machine learning models are coupled to determine the dominating geological and engineering *** Shapley value with definite physical meaning is employed to quantitatively measure the effects of individual factors.A multi-model-fused stacked model is trained for production forecast,which provides the basis for derivative-free optimization algorithms to optimize the development *** complete workflow is validated with actual production data collected from the Fuling shale gas field,Sichuan Basin,*** validation results show that the proposed procedure can draw rigorous conclusions with quantified evidence and thereby provide specific and reliable suggestions for development plan *** with traditional and experience-based approaches,the hybrid data-driven procedure is advanced in terms of both efficiency and accuracy.

关键词： Shale gas Production performance Data-driven Dominant factors Game theory Machine learning Derivative-free optimization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparison of Ozone and PM2.5 Concentrations over Urban,Suburban,and Background Sites in China

引用

Advances in Atmospheric Sciences 2020年第12期37卷 1297-1309,I0001-I0004页

作者： Lan GAO Xu YUE Xiaoyan meng Li DU Yadong LEI Chenguang tian Liang qiu Climate Change Research Center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control Collaborative Innovation Center of Atmospheric Environment and Equipment TechnologySchool of Environment Science and EngineeringNanjing University of Information Science&TechnologyNanjing 210044China China National Environmental Monitoring Center Beijing 100012China School of Atmospheric Sciences Chengdu University of Information and TechnologyChengdu 610225China

Surface ozone(O3)and fine particulate matter(PM2.5)are dominant air pollutants in *** of these pollutants can show significant differences between urban and nonurban ***,such contrast has never been explored on the country *** study investigates the spatiotemporal characteristics of urban-to-suburban and urban-tobackground difference for O3(Δ[O3])and PM2.5(Δ[PM2.5])concentrations in China using monitoring data from 1171 urban,110 suburban,and 15 background sites built by the China National Environmental Monitoring Center(CNEMC).On the annual mean basis,the urban-to-suburbanΔ[O3]is−3.7 ppbv in Beijing-tianjin-Hebei,1.0 ppbv in the Yangtze River Delta,−3.5 ppbv in the Pearl River Delta,and−3.8 ppbv in the Sichuan *** the contrary,the urban-to-suburbanΔ[PM2.5]is 15.8,−0.3,3.5 and 2.4μg m^−3 in those areas,*** urban-to-suburban contrast is more significant in winter for bothΔ[O3]andΔ[PM2.5].In eastern China,urban-to-background differences are also moderate during summer,with−5.1 to 6.8 ppbv forΔ[O3]and−0.1 to 22.5μg m^−3 forΔ[PM2.5].However,such contrasts are much larger in winter,with−22.2 to 5.5 ppbv forΔ[O3]and 3.1 to 82.3μg m^−3 forΔ[PM2.5].Since the urban region accounts for only 2%of the whole country’s area,the urban-dominant air quality data from the CNEMC network may overestimate winter[PM2.5]but underestimate winter[O3]over the vast domain of *** study suggests that the CNEMC monitoring data should be used with caution for evaluating chemical models and assessing ecosystem health,which require more data outside urban areas.

关键词： ozone PM2.5 urban suburban background

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：