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DIFFUSION THEORY WITH INFRARED DIVERGENcE

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Science in china,Ser.A 1982年第1期 59-71页

作者：刘福绥倪嘉陵 Department of Physics Peking University Naval Research Laboratory washington D. c. S A

According to a recently advanced unified theory of low frequency fluctuation-dissipationproperties of condensed matter, we have extended the classical Markovian diffusion transportto non-Markovian diffusion transport. The theory involves a single parameter n, the infrareddivergence exponent. The new results derived in this work include the 1/f~β diffusion noisespectrum where β tends to unity when n approaches its limiting value of unit, a modified Ein-stein relation between mean square displacement and time of diffusion, time dependent diffusioncoefficient and mobility, with their ratio now obeying a generalized Nernst-Einstein *** results are especially relevant to diffusion in non-crystalline condensed matter.

关键词： DIFFUSION THEORY WITH INFRARED DIVERGENcE

Pointed p^3-Dimensional Hopf Algebras in Positive characteristic

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Algebra colloquium 2018年第3期25卷 399-436页

作者： Van c. Nguyen Xingting Wang Department of Mathematics Hood College Frederick MD 21701 USA Department of Mathematics Howard University Washington DC 20059 USA

We focus on the classification of pointed p^3-dimensional Hopf algebras H over any algebraically closed field of prime characteristic p 〉 0. In particular, we consider certain cases when the group of grouplike elements is of order p or p^2 that is, when H is pointed but is not connected nor a group algebra. The structures of the associated graded algebra gr H are completely described as bosonizations of graded braided Hopf algebras over group algebras, and most of the lifting structures of H are given. This work provides many new examples of （parametrized） non-commutative, non-cocommutative finite- dimensional Hopf algebras in positive characteristic.

关键词： braided Hopfalgebras Yetter-Drinfeld modules positive characteristic pointed Hopf algebras Nichols algebras

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Participants’ Voices

Beijing Review 2010年第16期53卷 19-19页

作者： chen Wen from washington, D.c.

United States As the host of the Nuclear Security Summit in washington, D.c., President Barack Obama called for the securing of

关键词： Security Participants Voices

Phorbol-induced surface expression of NR2A subunit homologues in HEK293 cells

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Acta Pharmacologica Sinica 2006年第12期27卷 1580-1585页

作者： chan-ying ZHENG~2 Xiu-juan YANG~3 Zhan-yan FU~4 Jian-hong LUO~(2,5)2 Department of Neurobiology,Zhejiang University School of Medicine,Hangzhou 310031,china 3 Institute of Neuroscience,Shanghai Institutes for Biological Sciences,the chinese Academy of Sciences,Shanghai 200031,china 4 Department of Physiology and Biophysics,Georgetown University School of Medicine washington 20057,USA Department of Neurobiology Zhejiang University School of Medicine Hangzhou China Institute of Neuroscience Shanghai Institutes for Biological Sciences the Chinese Academy of Sciences Shanghai China Department of Physiology and Biophysics Georgetown University School of Medicine Washington USA

Aim:N-methyl-D-aspartate receptors(NMDAR)are heteromeric complexes pri-marily assembled from NR1 and NR2 *** normal conditions,NR2 sub-units assemble into homodimers in the endoplasmic reticulum(ER).Thesehomodimers remain in the ER until they coassemble with NR1 dimers and aretrafficked to the cell ***,it still remains unclear whether functionalhomomeric NMDAR exist in physiological or pathological ***:We transfected GFP-NR2A alone into HEK293 cells,treated the cells with PKcactivator 12-myristate-13 acetate(PMA),and then detected surface NR2A sub-units with a live cell immunostaining *** also used a series of NR2Amutants with a partial deletion of its c-terminus to identify the regions that areinvolved in the PMA-mediated surface expression of NR2A ***:NR2A subunits were expressed on the cell membrane after incubation with PMA(200 nmol/L,30 min),although no functional NMDA channels were detected afterPMA-induced membrane *** with an ER marker alsorevealed that NR2A subunits were exported from the ER after PMA ***,the deletion of amino acids between 1149-1347 or 1354-1464 ofNR2A inhibited PMA-induced surface expression ofNR2A ***:First,our data suggests that PMA treatment can induce the surface expression ofhomomeric NR2A ***,this process is probably mediated bythe NR2A c-terminal region between positions 1149 and 1464.

关键词： NMDA receptor NR2A subunit PMA surface expression HEK293 cells

AN EXPERIMENTAL SIMULATION ON THE STRUcTURE AND TOPOGRAPHIcAL INFLUENcE OF TYPHOON

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Science in china,Ser.A 1975年第3期 381-395页

作者：张捷迁魏鼎文何阜华 Professor of catholic University of America washington D. c. has worked in the Institute of Atmospheric Physics for a short period at the invitation of Academia Sinica.

With air as the working substance and infrared heating as energy source, typhoons aresimulated in a rotating chamber in the laboratory. The horizontal circulation on the threelayers and the vertical cross sections are given. They agree quite well with the real obser-vations. Several interesting results are obtained in a series of experiments on the motions oftyphoons under the influence of the topography along the SE coast of china. Amongthem the two important ones are: (1) When the typhoons approach Taiwan of chinafrom the cast or south-east, there appear two eyes, one to the SE and the other to theNW of Taiwan. (2) When the typhoons move toward the continent at a comparativelylarge angle, the motion is conspieuously speeding up with its centre drawing near the coast.

关键词： AN EXPERIMENTAL SIMULATION ON THE STRUcTURE AND TOPOGRAPHIcAL INFLUENcE OF TYPHOON

Effects of PGc-1αoverexpression on the myogenic response during skeletal muscle regeneration

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Sports Medicine and Health Science 2022年第3期4卷 198-208页

作者： Tyrone A.washington Wesley S.Haynie Eleanor R.Schrems Richard A.Perry Jr. Lemuel A.Brown Breanna M.Williams Megan E.Rosa-caldwell David E.Lee Jacob L.Brown Exercise Muscle Biology Laboratory Exercise Science Research CenterDepartment of HealthHuman Performance and RecreationUniversity of ArkansasFayettevilleAR72701USA cachexia Research Laboratory Exercise Science Research CenterDepartment of HealthHuman Performance and RecreationUniversity of ArkansasFayettevilleAR72701USA

The ability of skeletal muscle to regenerate from injury is crucial for locomotion,metabolic health,and quality of *** proliferator-activated receptor-γcoactivator-1α(PGc1A)is a transcriptional coactivator required for mitochondrial *** mitochondrial biogenesis is associated with improved muscle cell differentiation,however PGc1A's role in skeletal muscle regeneration following damage requires further *** purpose of this study was to investigate the role of skeletal muscle-specific PGc1A overexpression during regeneration following damage.22 c57BL/6J(WT)and 26 PGc1A muscle transgenic(A1)mice were injected with either phosphate-buffered saline(PBS,uninjured control)or Bupivacaine(MAR,injured)into their tibialis anterior(TA)muscle to induce skeletal muscle *** muscles were extracted 3-or 28-days postinjury and analyzed for markers of regenerative myogenesis and protein ***1a mRNA was~10–20 fold greater in A1 *** of protein synthesis,AKT and 4EBP1,displayed decreases in A1 mice compared to WT at both timepoints indicating a decreased protein synthetic *** mRNA was~75%lower compared to WT 3 days *** mice exhibited decreased cross-sectional area of the TA muscle at 28 days post-injection with bupivacaine compared to all other ***1A overexpression modifies the myogenic response during regeneration.

关键词： PGc-1α Skeletal muscle Muscle regeneration Satellite cells Protein turnover p38 MAPK

INTERNAL FRIcTION, DIELEcTRIc LOSS AND NMR RELAXATION IN IONIc cONDUcTORS

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chinese Science Bulletin 1982年第3期27卷 269-274页

作者：高国儒倪嘉陵 Institute of Physics Academia Sinica Naval Research Laboratory Washington D. C. 20375 U. S. A.

Ⅰ. INTRODUcTIONResponse functions containing infrared divergence effects are given in this paper. These functions assume the same form for NMR relaxation, dielectric loss and internal friction. Except the constant factor, T1-1, X″/βω and Q-1/βω have the same frequency and temperature dependence. Forthermore, in Na β-alumina in three cases, the exponents N of infrared divergence are all equal to 0.7. The theoretical apparent activa-

关键词： relaxation divergence dielectric assume apparent coordinates alumina absolute unified vibrating

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Tumor organoids to study gastroesophageal cancer: a primer

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Journal of Molecular cell Biology 2020年第8期12卷 593-606页

作者： Ramon U.Jin Jason c.Mills Division of Oncology Department of Internal MedicineWashington University School of MedicineSt.LouisMO 63130USA Division of Gastroenterology Department of Internal MedicineWashington University School of MedicineSt.LouisMO 63130USA Department of Developmental Biology Washington University School of MedicineSt.LouisMO 63130USA Department of Pathology and Immunology Washington University School of MedicineSt.LouisMO 63130USA

Gastroesophageal cancers are leading causes of cancer *** attempts at adopting molecularly based treatment approaches have been slow and ineffective even though we begin to identify specific targetable gene mutations and *** is dear that we should no longer treat all gastroesophageal cancers as a homogeneous disease,which is what we do when we use nonspecific ***,we currently cannot monitor successful gene/pathway targeting,nor understand how/when tumors develop resistance,nor predict which patients will derive maximal *** improve outcomes,we must precisely detail the heterogeneity of these tumors to then individualize cancer therapy as well as develop novel avenues to study and predict treatment effects in individual *** this end,patient-derived organoids,in which tumor cells from individual patients are grown in a Petri dish,are a new versatile system that allows for timely expandability,detailed molecular characterization,and genetic manipulation with the promise of enabling predictive assessment of treatment *** this review,we will explore the development and basic techniques for organoid generation,and discuss the current and potential future applications of this exciting technology to study the basic science of carcinogenesis and to predict/guide cancer patient care in the clinics.

关键词： targeted therapy precision oncology cancer model tumor heterogeneity cancer evolution personalized medicine

Insect herbivory immediately before the eclipse of the gymnosperms:The Dawangzhangzi plant assemblage of Northeastern china

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Insect Science 2022年第5期29卷 1483-1520页

作者： Lifang Xiao conrad c.Labandeira Dong Ren college of Life Science and Academy for Multidisciplinary Studies Capital Normal UniversityBejingChina Smithsonian Institution National Museum of Natural HistoryWashingtonDCUSA Department of Entomology and Bees Program University of MarylandCollege ParkMDUSA

The Early cretaceous terrestrial revolution involved global shifts from gymnosperm-to angiosperm-dominated ***,responses of insect herbivores to these changes remain *** evaluated 2176 highly sampled plant specimens representing 62 species/morphotypes from the 126 Ma Dawangzhangzi plant assemblage of Northeastern *** study consisted of horsetails,ferns,ginkgoaleans,czekanowskialeans,conifers,and an *** herbivory was evaluated by the functional feeding groups of hole feeding,margin feeding,and surface feeding(ectophytic feeders);piercer and suckers,and ovipositing insects(ectoendophytic feeders);mining,galling,and borings(endophytic feeders);and pathogens,collectively constituting 65 damage types(DTs).The plant assemblage was assessed for herbivory richness by DT richness,component community structure,and DT specialization on plant hosts;for herbivory intensity,it was evaluated for DT frequency,herbivorized surface area,and feeding event *** feeding event occurrences,the data supported seven species/morphotypes as most intensely herbivorized:Liaoningocladus boii(76.6%),czekanowskia sp.1(8.4%),czekanowskia rigida(4.10%),Lindleycladus lanceolatus(3.5%),Ginkgoites sp.2(2.0%),Podozamites sp.1(1.1%),and Solenites sp.1(0.9%).The most herbivorized taxa were pinaleans(conifers),then czekanowskialeans,and lastly ginkgoaleans;the monodominant component community was the conifer Liaoningocladus *** host specialization levels were *** plant assemblage had an overall low 0.86%of foliage removed by herbivores,explained by physical and chemical antiherbivore defenses,and parasitoid *** Paleozoic,gymnosperm-dominated assemblages had greater herbivory,component community structure of the three most herbivorized taxa are more similar to modern bracken fern and willow than modern gymnosperm taxa.

关键词： broadleaved conifer cretaceous terrestrial revolution czekanowskia damage type herbivory index Liaoningocladus boit Mesozoic ovipositor Yixian Formation