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Review and Outlook of 2007 China RE Market

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China Rare Earth Information 2008年第6期14卷 1-3页

作者： hong mei and wang Liqing

Management on rare earth mineral resources and integration of rare earth industry were further strengthened in 2007. Price of predominant minerals rebounded largely last year. Price of different RE elements varied a lor. Some products like lanthanum and cerium were oversupply. While price of NdFeB magnetic materials related products, like neodymium and praseodymium generally went up in the first half year and down in the second half.

关键词：矿业稀土元素中国 2007年市场分析

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miR-181b promotes angiogenesis and neurological function recovery after ischemic stroke

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Neural Regeneration Research 2023年第9期18卷 1983-1989页

作者： Li-Xia Xue Lin-Yuan Shu hong-mei wang Kai-Li Lu Li-Gang Huang Jing-Yan Xiang Zhi Geng Yu-Wu Zhao Hao Chen Department of Neurology Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghaiChina Department of Emergency Medicine Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghaiChina Department of Neurosurgery Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghaiChina

Promotion of new blood vessel formation is a new strategy for treating ischemic ***-coding miRNAs have been recently considered potential therapeutic targets for ischemic ***-181b has been shown to promote angiogenesis in hypoxia and traumatic brain injury model,while its effect on ischemic stroke remains *** this study,we found that overexpression of miR-181b in brain microvascular endothelial cells subjected to oxygen-glucose deprivation in vitro restored cell prolife ration and enhanced *** rat models of focal cerebral ischemia,ove rexpression of miR-181b reduced infarction volume,promoted angiogenesis in ischemic penumbra,and improved neurological *** further investigated the molecular mechanism by which miR-181b participates in angiogenesis after ischemic stroke and found that miR-181b directly bound to the 3’-UTR of phosphatase and tensin homolog(PTEN) mRNA to induce PTEN downregulation,leading to activation of the protein kinase B(Akt) pathway,upregulated expression of vascular endothelial growth facto rs,down-regulated expression of endostatin,and promoted *** togethe r,these results indicate that exogenous miR-181b exhibits neuroprotective effects on ischemic stro ke through activating the PTEN/Akt signal pathway and promoting angiogenesis.

关键词： Akt angiogenesis endostatin ischemic stroke middle cerebral artery occlusion miR-181b neurological function recovery oxygen-glucose deprivation PTEN vascular endothelial growth factor

STUDY OF COMPLEXATION OF BARBITURATES WITH β-CYCLODEXTRIN

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Chinese Chemical Letters 1993年第12期4卷 1085-1088页

作者： Xue mei wang hong Yuan CHEN Department of Chemistry,Nanjing University,210008 Nanjing

The nature of the quenching of barbiturate fluorescence by forming inclusion complexcs with β-cyclodextrin is investigated principally using fluorescence/absorption and Fourier transform infrared(FTIR)*** relatively weak complexes formed in aqueous solutions indicated through the IR spectroscopies are confirmed by the apparent formation constants acquired by using fluorescence *** specific information concerning the mechanisms of interaction has been ex- plored in detail by means of the analysis of the electrochemical and spectroscopic behaviour.

关键词： CYCLODEXTRIN STUDY OF COMPLEXATION OF BARBITURATES WITH TIR

CHARACTERIZATION OF THE β-CYCLODEXTRIN/QUININE COMPLEX

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Chinese Chemical Letters 1994年第5期5卷 399-402页

作者： Xue mei wang and hong Yuan CHEN (Department of Chemistry, Nanjing University. Nanjing 210008)

Fourier transform infrared (FTIR) studies of the complexation of quinine hydtoohloride with β-cyclodextrin (β-CD) in aqueous solution have been carried out, it can afford direct evidence relative to the molecular structure of the complex as well as fresh insight into the molecular interactions of the cyclodextrin system.

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SOLID STATE PHOTOREACTION OF N-HETERO-CYCLIC COMPOUNDS

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Chinese Chemical Letters 1993年第2期4卷 115-118页

作者： Ji Ben MENG Wen Guang wang Yong mei wang hong Gen wang Department of Chemistry and Central Laboratory,Nankai University Tianjin 300071

Photochemical reactions of 3-methylindole,carbazole,benzimidazole with fused polycyclic aromatic hydrocarbons in solid state were investigated,The structures of 4 new compounds were confirmed by IR,UV,\+1HNNR,MS and e... 详细信息

关键词： IR SOLID STATE PHOTOREACTION OF N-HETERO-CYCLIC COMPOUNDS ppm KBr

Dual effects of 8-Br-cAMP on differentiation and apoptosis of human esophageal cancer cell line Eca-109

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World Journal of Gastroenterology 2005年第41期11卷 6538-6542页

作者： hong-mei wang Nai-Gang Zheng Jing-Lan Wu Cui-Cui Gong Yi-Ling wang Department of Laboratory Medicine First Affiliated Hospital of Zhengzhou University Zhengzhou 450052Henan Province China Molecular Cell Biology Research Center Zhengzhou University Zhengzhou 450052 Henan Province China Laboratory Medicine Center PLA No. 153 Hospital Zhengzhou 450042 Henan Province China

AIM: To investigate the effects of 8-Br-cAMP on differentiation and apoptosis of human esophageal cancer cell line Eca-109, and the related gene ***: The cultured Eca-109 cells were divided into four groups: E1 group (co-cultured with 8-Br-cAMP for 24 h); E2 group (co-cultured with 8-Br-cAMP for 48 h); C1 group (treated without 8-Br-cAMP for 24 h); and C2 group (treated without 8-Br-cAMP for 48 h). The same concentration of cell suspension of each group was dropped separately onto the slides and nitrocellulose membranes (NCM). The biotin-labeled cDNA probes for c-myc, wild-type (wt) p53, bcl-2 and iNOS were prepared for in situ hybridization. The expressions of epidermal growth factor receptor (EGFR), p38 kinase, FAS, FasL and caspase-3 were detected using immunocytochemistry, and the NOS activity and the ratio of differentiated cells/proliferating cells were examined by cytochemistry. Immunocytochemistry, cytochemistry,and in situ hybridization were separately carried out on both slides and NCM specimens for each group. In addition, TUNEL was used to detect the cell apoptosis rate in each ***: The apoptotic rate of E2 group was significantly higher compared to E1 group, while there was no difference in the ratio of differentiated cells/ proliferating cells between E1 and E2 groups. The signals of wt p53 and iNOS were markedly stronger, while the signals of c-myc and EGFR were obviously weaker in E1 group than those in C1 group (P＜0.05). Moreover, the signals of wt p53, iNOS, p38 kinase, caspase-3 and NOS activity were significantly stronger, whereas, the signals of bcl-2, c-myc and Fas/FasL were markedly weaker in E2 group than those in C2 group (P＜0.05). CONCLUSION: The differentiation and apoptosis of human esophageal cancer cell Eca-109 can be induced after 24- and 48-h treatment with 8-BrcAMP, respectively. Upregulation of wt p53, iNOS and downregulation of c-myc may be associated with differentiation and apoptosis of Eca-109 ***

关键词： Differentiation Apoptosis Gene expression 8-Br-cAMP Eca-109 cell line

RESEARCH ON THERMOREACTIONS BETWEEN INDOLE AND 9,10-PHENANTHRAQUINONE

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Chinese Chemical Letters 1993年第10期4卷 865-868页

作者： Ji Ben MENG Zhong WEN Yong mei wang hong Gen wang Department of Chemistry and Central Laboratory,Nankai University,Tianjin,300071

Solventless reactions between indole and 9,10-phenanthraquinone(PQ)have been carried out in the presence/absence of zinc *** 1,2-photoadduct between indole and PQ was identified as a possible intermediate in *** elect... 详细信息

关键词： ppm In RESEARCH ON THERMOREACTIONS BETWEEN INDOLE AND 9,10-PHENANTHRAQUINONE

SOLVENTLESS CYCLOCONDENSATIONS BETWEEN 1-NAPHTHOL AND BENZILS

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Chinese Chemical Letters 1993年第10期4卷 861-864页

作者： Ji Ben MENG Zhong WEN Yong mei wang hong Gen wang Department of Chemistry and Central Laboratory,Nankai University,Tianjin,300071

In the absence of organic solvents,the Lewis acid catalyzed cyclocondensation reactions between 1-naphthol and benzils gave 3-aryl-3-aryl'naphtho[1,2-b]furan-2(3H)-ones(NFs) in good yields(62%～70%)An electrophilic su... 详细信息

关键词： IR SOLVENTLESS CYCLOCONDENSATIONS BETWEEN 1-NAPHTHOL AND BENZILS KBr NF

CHEMICAL MODIFICATION OF TRYPTOPHAN RESIDUES IN POLYGALACTURONASE

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Chinese Chemical Letters 1994年第4期5卷 315-316页

作者： Lan Ying LIU hong mei wang, Jia Li LIU(Department of Molecular Biology Jilin Universityi, Changchun 130023)

Tryptophan (Trp) residues in polygalacturonase (PG) have been modified by N-bromosuccinimide (NBS). The results indicate that there are six tryptophan residues in PG and two of them are located on the surface of the enzyme. Among the six Trp residues, one is essential for the activity of the enzyme, which may be located at the substrate *** site of the enzyme, while others are nonessential. The spectra of circular dichroism (CD) of PG are changed after treatment with NBS.

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