检索结果-南通市图书馆

Acta Metallurgica Sinica(English Letters) 2021年第8期34卷 1029-1041页

作者： Shuai Zhang Bao-Chang liu mei-xuan li Hui-Yuan Wang Yin-Long Ma Key Laboratory of Drilling and Exploitation Technology in Complex Conditions of Ministry of Land and Resources College of Construction EngineeringJilin UniversityNo.938 Ximinzhu StreetChangchun 130026China Key Laboratory of Automobile Materials of Ministry of Education School of Materials Science and EngineeringJilin UniversityNanling CampusNo.5988 Renmin StreetChangchun 130025China

The effect of textures on different surfaces of an as-extruded Mg-4 Al-1 Sn-1 Zn(ATZ411) alloy sheet on its corrosion behavior was systematically investigated. The microstructure was examined by optical/scanning electron microscopy. The texture was characterized by X-ray diffraction and electron backscatter diffraction. The corrosion performance was evaluated by immersion tests, electrochemical measurements, and corrosion morphology observation. The results showed that there were obvious differences in the corrosion morphology and corrosion resistance on different surfaces. The surface perpendicular to extrusion direction had better corrosion resistance and more uniform corrosion damage than that perpendicular to the normal direction and that perpendicular to the transverse direction in 3.5 wt% NaCl solution. The corrosion morphology was mainly determined by the distribution of the second phase and fine-grained regions. The corrosion rate was more related to the overall texture.

关键词： Corrosion behavior Micro-galvanic Magnesium alloys Texture Extrusion

Reporting and methodological quality of meta-analyses of acupuncture for patients with migraine:A methodological investigation with evidence map

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2022年第3期20卷 213-220页

作者： Ting-ting Lu Cun-cun Lu mei-xuan li li-xin Ke Hui Cai Ke-hu Yang Institution of Clinical Research and Evidence-Based Medicine Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina Evidence-Based Medicine Center School of Basic Medical SciencesLanzhou UniversityLanzhou 730000Gansu ProvinceChina Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province Lanzhou 730000Gansu ProvinceChina Hepatobiliary and Pancreatic Center the First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080Guangdong ProvinceChina General Surgery Clinical Medical Center Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina

Background:Acupuncture has been widely used to relieve migraine-related ***,the findings of previous systematic reviews(SRs)and meta-analyses(MAs)are still not completely *** quality is also unknown,so a comprehensive study is ***:To evaluate the reporting and methodological quality of these MAs concerning acupuncture for migraine,and summarize evidence about the efficacy and safety of acupuncture for *** strategy:Pub Med,Embase,Cochrane library,China National Knowledge Infrastructure,Chinese Biomedical Databases,Wanfang Data,and VIP databases were searched from inception to September 2020,with a comprehensive search *** criteria:The pairwise MAs of randomized controlled trials(RCTs)concerning migraine treated by acupuncture or acupuncture-based therapies,with a control group that received sham acupuncture,medication,no treatment,or acupuncture at different acupoints were *** extraction and analysis:Two independent investigators screened studies,extracted relevant data,and assessed reporting and methodological quality using Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)2009 and A Measurement Tool to Assess Systematic Reviews 2(AMSTAR 2),then all results were *** correlation test was used to evaluate the correlation between reporting and methodological quality ***:A total of 20 MAs were included in this *** included MAs indicated that acupuncture was efficacious and safe in preventing and treating migraine when compared with control *** was a high correlation between reporting and methodological quality scores(rs=0.87,Plity of the included SRs needs to be improved mainly with regard to protocol and prospective registration,using a comprehensive search strategy,summarizing the strength of evidence body for key outcomes,a full list of excluded studies with reasons for exclusion,reporting of RCTs’fundin

关键词： Migraine Acupuncture Systematic review Meta-analysis AMSTAR 2 PRISMA

A corrosion-resistant and age-hardenable Mg-Al-Mn-Ca-Ce dilute alloy with fine-grained structure processed by controlled rolling

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2023年第32期163卷 223-236页

作者： Jia-Sheng li mei-xuan li Zhen-Ming Hua Yuan-Ting Mo Kai Guan Min Zha Yipeng Gao Hui-Yuan Wang Key Laboratory of Automobile Materials of Ministry of Education&School of Materials Science and Engineering Nanling CampusJilin UniversityChangchun 130025China State Key Laboratory of Automotive Simulation and Control Jilin UniversityChangchun 130012China International Center of Future Science Jilin UniversityChangchun 130012China

Low strength and poor corrosion resistance are two long-standing bottlenecks with dilute Mg ***,we report that the corrosion resistance of Mg-0.6Al-0.5Mn-0.2Ca(wt.%)alloy sheet can be significantly improved by micro-alloying with 0.3 wt.%Ce,and the strength can be considerably augmented after aging *** optimization of strength,ductility,and corrosion resistance is difficult due to the inherent trade-off in Mg ***,our aged Mg-0.6Al-0.5Mn-0.2Ca-0.3Ce alloy features with yield strength(YS)of∼194 MPa,ultimate tensile strength(UTS)of∼265 MPa,elongation to failure(EF)of∼17.2%,and corrosion rate(CR)of 2.2 mm y^(−1),the combination of which exhibits competitive advantage over other comparative dilute Mg *** is found that Ce addition decreases the activity of cathodic phases,inhibits detrimental effects of Fe impurities,and forms a protective Ce-containing surface *** high strength stems from the precipitation of ordered Guinier-Preston(G.P.)zones dispersed in uniform fine grains with an average grain size of∼8.2μ*** atomic-scale *** result in a noticeable age hardening response but do not act as crack initiation and propagation site,so our alloy also performs satisfactory *** work sheds light on the design and fabrication of strong,ductile,and corrosion-resistant dilute magnesium alloys to be used in electronic products and automotive bodies.

关键词： Magnesium alloy Micro-alloying Aging G.P.zones Mechanical property Corrosion

Recent progress in self-repairing coatings for corrosion protection on magnesium alloys and perspective of porous solids as novel carrier and barrier

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2023年第10期11卷 3585-3608页

作者： Yajie Yang Yufei Wang mei-xuan li Tianshuai Wang Dawei Wang Cheng Wang Min Zha Hui-Yuan Wang Key Laboratory of Automobile Materials of Ministry of Education&School of Materials Science and Engineering Jilin UniversityChangchun 130022China School of Materials Science and Engineering Hebei University of TechnologyTianjin 300130China International Center of Future Science Jilin UniversityChangchun 130012China

Featuring low density and high specific strength, magnesium(Mg) alloys have attracted wide interests in the fields of portable devices and automotive industry. However, the active chemical and electrochemical properties make them susceptible to corrosion in humid, seawater, soil,and chemical medium. Various strategies have revealed certain merits of protecting Mg alloys. Therein, engineering self-repairing coatings is considered as an effective strategy, because they can enable the timely repair for damaged areas, which brings about long-term protection for Mg alloys. In this review, self-repairing coatings on Mg alloys are summarized from two aspects, namely shape restoring coatings and function restoring coatings. Shape restoring coatings benefit for swelling, shrinking, or reassociating reversible chemical bonds to return to the original state and morphology when coatings broken;function self-repairing coatings depend on the release of inhibitors to generate new passive layers on the damaged areas. With the advancement of coating research and to fulfill the demanding requirements of applications, it is an inevitable trend to develop coatings that can integrate multiple functions(such as stimulus response, self-repairing, corrosion warning,and so on). As a novel carrier and barrier, porous solids, especially covalent organic frameworks(COFs), have been respected as the future development of self-repairing coatings on Mg alloys, due to their unique, diverse structures and adjustable functions.

关键词： Mg alloys Coatings Self-repairing Corrosion protection Porous solids

Simultaneous refinement of α-Mg grains and β-Mg_(17)Al_(12) in Mg-Al based alloys via heterogeneous nucleation on Al_(8)Mn_(4)Sm

在线全文

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2023年第1期11卷 348-360页

作者： Jun-Chen Chen mei-xuan li Zhi-Yang Yu Zhao-Yuan Meng Cheng Wang Zhi-Zheng Yang Hui-Yuan Wang State Key Laboratory of Automotive Simulation and Control Jilin UniversityChangchun 130012PR China Key Laboratory of Automobile Materials of Ministry of Education&School of Materials Science and Engineering Jilin UniversityNanling CampusNo.5988 Renmin StreetChangchun 130025PR China International Center of Future Science Jilin UniversityChangchun 130012PR China

Due to the significant differences in the formation temperature and crystal structure between the primaryα-Mg and eutecticβ-Mg_(17)Al_(12),it is a great challenge to achieve simultaneous refinement of the primary and eutectic phases in Mg-Al based alloys via heterogeneous ***,we found that theα-Mg andβ-Mg_(17)Al_(12) in the AZ80 alloy can be simultaneously refined after 0.2 wt.%Sm addition,with the grain size decreasing from∼217±15μm to∼170±10μm and theβ-Mg_(17)Al_(12) morphology changing from a typical continuous network to a nod-like or spherical *** simultaneous refinement mechanism is investigated through solidification simulation,transmission electron microscopy(TEM),and differential thermal analysis(DTA).In the AZ80-0.2Sm alloy,many Al8Mn4Sm particles can be observed near the center of theα-Mg grains or inside theβ-Mg_(17)Al_(12).Crystallographic calculations further reveal that the Al8Mn4Sm has good crystallographic matching with both theα-Mg andβ-Mg_(17)Al_(12),so it possesses the potency to serve as heterogeneous nucleation sites for both *** promoted heterogeneous nucleation on the Al8Mn4Sm decreases the undercooling required by the nucleation of the primary and eutectic phases,which enhances the heterogeneous nucleation rate,thus causing the simultaneous refinement of theα-Mg andβ-Mg_(17)Al_(12).The orientation relationships between the Al8Mn4Sm and Mg/Mg_(17)Al_(12) are identified,which are[1210]_(Mg)//[010]_(Al8Mn4Sm),(1010)_(Mg)//(301)_(Al8Mn4Sm) and[112]_(Mg_(17)Al_(12))//[010]_(Al8Mn4Sm),(110)_(Mg_(17)Al_(12))//(301)_(Al8Mn4Sm),***,the refinement of theβ-Mg_(17)Al_(12) accelerates its dissolution during the solution treatment,which is beneficial for cost saving in industrial *** Al8Mn4RE compounds such as Al8Mn4Y might have the same positive effect on the simultaneous refinement due to the similar physicochemical properties of rare earth *** work not only proves the po

关键词： Magnesium alloys Microstructure refinement Primaryα-Mg Eutecticβ-Mg_(17)Al_(12) Rare earth Heterogeneous nucleation

C-X-C chemokine receptor type 7 antibody enhances neural plasticity after ischemic stroke

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第9期18卷 1976-1982页

作者： Xiao-Qian Zhang Xiao-Yin Wang Bing-Chao Dong mei-xuan li Yu Wang Ting Xiao Shan-Shan Zhao Department of Neurology The First Hospital of China Medical UniversityShenyangLiaoning ProvinceChina Key Laboratory of Immunodermatology Ministry of HealthMinistry of EducationShenyangLiaoning ProvinceChina

Stromal cell-derived factor-1 and its receptor C-X-C chemokine receptor 4(CXCR4) have been shown to regulate neural regeneration after *** r,whether stromal cell-derived factor-1 receptor CXCR7,which is widely distributed in the develo ping and adult central nervous system,participates in neural regeneration remains poorly unde *** this study,we established rat models of focal cerebral ischemia by injecting endothelin-1 into the cerebral co rtex and *** on day 7 after injury,CXCR7-neutralizing antibody was injected into the lateral ventricle using a micro drug delivery system for 6 consecutive *** results showed that CXCR7-neutralizing antibody increased the total length and number of sprouting co rticospinal tra ct fibers in rats with cerebral ischemia,increased the expression of vesicular glutamate transporter 1 and growth-related protein 43,marke rs of the denervated spinal cord synapses,and promoted the differentiation and maturation of oligodendrocyte progenitor cells in the *** addition,CXCR7 antibody increased the expression of CXCR4 in the striatum,increased the protein expression of RAS and ERK1/2 associated with the RAS/ERK signaling pathway,and im proved rat motor *** findings suggest that CXCR7 improved neural functional recovery after ischemic stroke by promoting axonal regeneration,synaptogenesis,and myelin regeneration,which may be achieved by activation of CXCR4 and the RAS/ERK1/2 signaling pathway.

关键词： axonal regeneration cerebral ischemia C-X-C chemokine receptor 4 CXCR7 antibody neural plasticity RAS/ERK pathway remyelination stroke stromal cell-derived factor-1 synaptogenesis

Effects of CXCR7-neutralizing antibody on neurogenesis in the hippocampal dentate gyrus and cognitive function in the chronic phase of cerebral ischemia

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2020年第6期15卷 1079-1085页

作者： Bing-Chao Dong mei-xuan li Xiao-Yin Wang Xi Cheng Yu Wang Ting Xiao Jukka Jolkkonen Chuan-Sheng Zhao Shan-Shan Zhao Department of Neurology The First Hospital of China Medical UniversityShenyangLiaoning ProvinceChina Key Laboratory of Immunodermatology Ministry of HealthMinistry of EducationShenyangLiaoning ProvinceChina Department of Neurology Institute of Clinical MedicineUniversity of Eastern FinlandKuopioFinland

Stromal cell-derived factor-1 and its receptor CXCR4 are essential regulators of the neurogenesis that occurs in the adult hippocampal dentate ***,the effects of CXCR7,a new atypical receptor of stromal cell-derived factor-1,on hippocampal neurogenesis after a stroke remain largely *** study is the first to investigate the effect of a CXCR7-neutralizing antibody on neurogenesis in the dentate gyrus and the associated recovery of cognitive function of rats in the chronic stage of cerebral *** rats were randomly divided into sham,sham+anti-CXCR7,ischemia and ischemia+anti-CXCR7 ***-1 was injected in the ipsilateral motor cortex and striatum to induce focal cerebral *** group rats were injected with saline instead of endothelin-1 via intracranial *** sham and ischemic rats were treated with intraventricular infusions of CXCR7-neutralizing antibodies for 6 days 1 week after *** staining with doublecortin,a marker for neuronal precursors,was performed to assess the neurogenesis in the dentate *** found that anti-CXCR7 antibody infusion enhanced the proliferation and dendritic development of doublecortin-labeled cells in the dentate gyrus in both ischemic and sham-operated *** learning and memory functions were assessed by Morris water maze tests 30-32 days after ***7-neutralizing antibody treatment significantly reduced the escape latency of the spatial navigation trial and increased the time spent in the target quadrant of spatial probe trial in animals that received ischemic insult,but not in sham operated *** results suggest that CXCR7-neutralizing antibody enhances the neurogenesis in the dentate gyrus and improves the cognitive function after cerebral ischemia in *** animal experimental protocols and procedures were approved by the Institutional Animal Care and Use Committee of China Medical University(CMU16089 R)on December 8,2016.

关键词： cerebral ischemia cognitive function CXCR7 dendritic development dentate gyrus doublecortin neurogenesis neutralizing antibody stroke stromal cell-derived factor-1

Neuronal nitric oxide synthase/reactive oxygen species pathway is involved in apoptosis and pyroptosis in epilepsy

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第6期18卷 1277-1285页

作者： Xiao-Xue Xu Rui-Xue Shi Yu Fu Jia-Lu Wang Xin Tong Shi-Qi Zhang Na Wang mei-xuan li Yu Tong Wei Wang Miao He Bing-Yang liu Gui-Lan Chen Feng Guo Department of Pharmaceutical Toxicology School of Pharmaceutical ScienceChina Medical UniversityShenyangLiaoning ProvinceChina Department of Neurology the First Affiliated Hospital of China Medical UniversityShenyangLiaoning ProvinceChina Key Laboratory of Medical Electrophysiology Ministry of Education&Medical Electrophysiological Key Laboratory of Sichuan ProvinceInstitute of Cardiovascular ResearchSouthwest Medical UniversityLuzhouSichuan ProvinceChina Department of Endocrinology and Metabolism the Fourth Affiliated Hospital of China Medical UniversityShenyangLiaoning ProvinceChina Department of Endocrinology Shengjing Hospital of China Medical UniversityShenyangLiaoning ProvinceChina

Dysfunction of neuronal nitric oxide synthase contributes to neurotoxicity,which triggers cell death in various neuropathological diseases,including *** have shown that inhibition of neuronal nitric oxide synthase activity increases the epilepsy threshold,that is,has an anticonvulsant ***,the exact role and potential mechanism of neuronal nitric oxide synthase in seizures are still *** this study,we performed RNA sequencing,functional enrichment analysis,and weighted gene coexpression network analysis of the hippocampus of tremor rats,a rat model of genetic *** found damaged hippocampal mitochondria and abnormal succinate dehydrogenase level and Na+-K+-ATPase *** addition,we used a pilocarpine-induced N2a cell model to mimic epileptic *** application of neuronal nitric oxide synthase inhibitor 7-nitroindazole,changes in malondialdehyde,lactate dehydrogenase and superoxide dismutase,which are associated with oxidative stress,were reversed,and the increase in reactive oxygen species level was reversed by 7-nitroindazole or reactive oxygen species inhibitor *** of 7-nitroindazole or N-acetylcysteine downregulated the expression of caspase-3 and cytochrome c and reversed the apoptosis of epileptic ***,7-nitroindazole or N-acetylcysteine downregulated the abnormally high expression of NLRP3,gasdermin-D,interleukin-1βand *** indicated that 7-nitroindazole and N-acetylcysteine each reversed epileptic cell *** together,our findings suggest that the neuronal nitric oxide synthase/reactive oxygen species pathway is involved in pyroptosis of epileptic cells,and inhibiting neuronal nitric oxide synthase activity or its induced oxidative stress may play a neuroprotective role in epilepsy.

关键词： apoptosis bioinformatics analysis cell death epilepsy nitric oxide synthase oxidative stress pyroptosis RNA sequencing Tremor rat weighted gene co-expression network analysis

Cell polarization in ischemic stroke: molecular mechanisms and advances

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第3期20卷 632-645页

作者： Yuanwei li Xiaoxiao Xu xuan Wu Jiarui li Shiling Chen Danyang Chen Gaigai li Zhouping Tang Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.

关键词： astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke

Wafer-Scale Vertical 1D GaN Nanorods/2D MoS₂/PEDOT:PSS for Piezophototronic Effect-Enhanced Self-Powered Flexible Photodetectors

在线全文

学校读者我要写书评

暂无评论

NANO-MICRO LETTERS 2025年第1期17卷 1-15页

作者： Tang, Xin Jiang, Hongsheng lin, Zhengliang Wang, xuan Wang, Wenliang li, Guoqiang South China Univ Technol State Key Lab Luminescent Mat & Devices Guangzhou 510640 Peoples R China South China Univ Technol Sch Mat Sci & Engn Dept Elect Mat Guangzhou 510640 Peoples R China

Vertical 1D GaN nanorod arrays/2D MoS2/PEDOT:PSS heterostructures in wafer scale have been fabricated for flexible photodetection ***-powered flexible photodetector at compressive strain reveals a significantly enhanced photoresponse with a responsivity of 2.47 A W-1 and response times of 40/45 mu s, which are superior to the state-of-the-art flexible *** work not only provides a valuable strategy for the design and construction of tunable van der Waals heterostructures, but also opens a new opportunity for flexible sensors. van der Waals (vdW) heterostructures constructed by low-dimensional (0D, 1D, and 2D) materials are emerging as one of the most appealing systems in next-generation flexible photodetection. Currently, hand-stacked vdW-type photodetectors are not compatible with large-area-array fabrication and show unimpressive performance in self-powered mode. Herein, vertical 1D GaN nanorods arrays (NRAs)/2D MoS2/PEDOT:PSS in wafer scale have been proposed for self-powered flexible photodetectors arrays firstly. The as-integrated device without external bias under weak UV illumination exhibits a competitive responsivity of 1.47 A W-1 and a high detectivity of 1.2 x 1011 Jones, as well as a fast response speed of 54/71 mu s, thanks to the strong light absorption of GaN NRAs and the efficient photogenerated carrier separation in type-II heterojunction. Notably, the strain-tunable photodetection performances of device have been demonstrated. Impressively, the device at - 0.78% strain and zero bias reveals a significantly enhanced photoresponse with a responsivity of 2.47 A W-1, a detectivity of 2.6 x 1011 Jones, and response times of 40/45 mu s, which are superior to the state-of-the-art self-powered flexible photodetectors. This work presents a valuable avenue to prepare tunable vdWs heterostructures for self-powered flexible photodetection, which performs well in flexible sensors.

关键词： Vertical nanorod arrays van der Waals heterostructure Piezophototronic effect Self-powered photodetection Flexible sensors