检索结果-南通市图书馆

Recent updates on nano-phyto-formulations based therapeutic intervention for cancer treatment

Oncology Research 2024年第1期32卷 19-47页

作者： ABHISHEK WAHI MAMTA BISHNOI NEHA RAINA meghna amrita singh PIYUSH VERMA PIYUSH KUMAR GUPTA GINPREET KAUR HARDEEP singh TULI MADHU GUPTA Department of Pharmaceutics School of Pharmaceutical SciencesDelhi Pharmaceutical Sciences and Research University(DPSRU)Pushp ViharNew Delhi110017India Department of Pharmaceutical Sciences Gurugram UniversityHaryana122003India Department of Life Sciences Sharda School of Basic Sciences and ResearchSharda UniversityGreater NoidaUttar Pradesh201310India Department of Biotechnology Graphic Era(Deemed to be University)DehradunUttarakhand248002India Department of Pharmacology Shobhaben Pratapbhai Patel School of Pharmacy&Technology ManagementSVKM’s NMIMSVile Parle(West)Mumbai400056India Department of Bio-Sciences and Technology Maharishi Markandeshwar Engineering CollegeMaharishi Markandeshwar(Deemed to be University)MullanaAmbala133207India

Cancer is a leading cause of death globally,with limited treatment options and several *** agents often result in toxicity which long-term conventional *** are natural constituents that are more effective in treating various diseases with less toxicity than the chemotherapeutic agents providing alternative therapeutic approaches to minimize the *** phytoconstituents act in several ways and deliver optimum effectiveness against ***,the effectiveness of phyto-formulations in the management of cancers may be constrained due to challenges related to inadequate solubility,bioavailability,and *** presents a promising avenue for transforming current cancer treatment methods through the incorporation of phytochemicals into nanosystems,which possess a range of advantageous characteristics such as biocompatibility,targeted and sustained release capabilities,and enhanced protective *** holds significant potential for future advancements in cancer ***,this review aims to provide intensive literature on diverse nanocarriers,highlighting their applications as cargos for phytocompounds in ***,it offers an overview of the current advancements in the respective field,emphasizing the characteristics that contribute to favourable outcomes in both in vitro and in vivo ***,clinical development and regulatory concerns are also discussed to check on the transformation of the concept as a promising strategy for combination therapy of phytochemicals and chemotherapeutics that could lead to cancer management in the future.

关键词： Phyto-formulations Cancer Nanocarriers Nanotechnology Clinical development

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oral cysticercosis-a rare presentation

引用

Asian Pacific Journal of Tropical Medicine 2011年第7期4卷 587-588页

作者： singh Sunita Chhabra Sonia Aggarwal Garima Kalra Rajnish Duhan amrita Sen Rajeev Department of Pathology Pt.B.D.Sharma PGIMSRohtakIndia

Cysticercosis is a condition that occurs when man is infected with larvae of Taenia *** cysticercosis is a rare event,and it represenls difficulty in clinical diagnosis.A case of oral cysticercosis in 11 year old girl is presented which complained of painless swelling for 6 months. A FNAC was performed which revealed bluish pink fibrillary material and interspersed nuclei and fragments of wall of *** was treated with antihelminthic.

关键词： Oral cysticercosis Taenia solium Cysticercus celiuiosae

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Isolated tuberculous splenic abscess in an immunocompetent individual

引用

Asian Pacific Journal of Tropical Medicine 2011年第1期4卷 81-82页

作者： Parveen Rana Kundu SK Mathur Sunita singh amrita Duhan Garima Aggarwal Rajeev Sen Department of Pathology Pt.B.D.Sharma PGIMSIndia

Tuberculosis(TB) of the spleen is an extremely rare clinical entity particularly among immunocompetent *** report a case of isolated tuberculous abscess of spleen in a 13- years- old *** primary focus of infection was detected in lungs or any other *** patient was treated by splenectomy after a therapeutic failure with standard antituberculous medication.

关键词： Spleen Tuberculosis Abscess

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Influence of Rind Hardness on Sugarcane Quality

引用

American Journal of Plant Sciences 2013年第8期4卷 45-52页

作者： Sujeet Pratap singh amrita Nigam Ram Kushal singh Centre for Sugarcane Biotechnology Sugarcane Research Institute U. P. Council of Sugarcane Research Shahjahanpur India School of Life Sciences Indira Gandhi National Open University New Delhi India.

Sugar recovery in a factory depends upon regular crushing and quality of varieties besides various other working parameters. Strategies for increased productivity and sugar recovery, varietal improvement can bring out through selection of parents to get maximum gains. These are governed by sugar content, fiber, rind hardness and cane yield. In order to assess the breeding value of different traits including rind hardness, study was undertaken at Sugarcane Research Institute, Shahjahanpur, during 2011-2012. Phenotypic difference and correlations among agronomic characters, basic quality characters and rind hardness in 120 segregating genotypes derived from contrast bi-parental cross (UP9530 × Co86011) of sugarcane cultivar were studied in this experiment. All the traits observed were found statistically significant among the mapping populations. The mean value of rind hardness was 5.91 with a range from 2.08 to 12.10 among 120 segregating population including their parents. Rind hardness (RHD) showed significant positive genotypic correlation with sugar yield-related traits viz;cane weight (CW, r = 0.325), cane yield (CYLD, r = 0.380) and sugar yield (SUYLD, r = 0.248). Significant negative correlation was observed for rind hardness with commercial cane sugar percent (CCS%, r = -0.388), number of millable cane (NMC, r = -0.216), hand refractometer brix %-October (HBR, r = -0.154), Brix% in juice (BR, r = -0.119) and Sucrose% in juice (SUC, r = -0.080). The simple correlation analysis showed that RHD, CW, CYLD and SUYLD showed significant positive correlation for agronomic characters, but for basic quality characters had negative correlations. Result indicated that rind hardness was found to have economically important trait due to showing significant positive and negative correlation with sugar yield and sugar content, respectively. The study also revealed that with the reduction in rind hardness, sugar recovery may increase. Present findings indicated that the rind

关键词： Rind Hardness Sugarcane Genetic Correlation Sugar Yield-Related Traits

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Newly identified genetic variant rs2294693 in UNC5CL gene is associated with decreased risk of esophageal carcinoma in the J&K Population–India

引用

BIOCELL 2021年第3期45卷 665-670页

作者： RUCHI SHAH SONALI VERMA amrita BHAT GH RASOOL BHAT VARUN SHARMA INDU SHARMA HEMENDER singh SANDEEP KAUL EKTA RAI SWARKAR SHARMA Human Genetics Research Group Shri Mata Vaishno Devi UniversityKatraJammu and Kashmir182320India Surgical Oncologist SMVD Narayana Super Specialty HospitalKatraJammu and Kashmir182320India

Esophageal cancer is the second most common type of cancer after lung carcinoma in the state of Jammu and Kashmir(J&K).The understanding of genetics in Esophageal cancer development is poor in the *** wide association studies(GWAS)has proved to be unsurpassed tool in identification of new loci associated with different *** in Chinese population has identified SNP rs2294693 present in UNC5CL(UNC-5 Family C-Terminal like)to be associated with non-cardia gastric *** performed a case control association study and genotyped the SNP rs2294693 using Taqman allele discrimination assay in 566 individuals(166 esophageal cancer patients and 400 controls)belonging to the J&K population.A statistically significant protective association with allelic odds ratio of 0.73(0.56–0.94 at 95%CI)and p value=0.016 was *** is the first study in relation to esophageal cancer in the Jammu and Kashmir population,so far it has been studied in association with gastric carcinoma in the Chinese population *** results indicate that the polymorphism rs2294693 is associated with esophageal cancer susceptibility and the mutant(T)allele might be a protective factor for esophageal cancer among Jammu and Kashmir *** the functional characterization of the variation is also warranted.

关键词： Esophageal cancer Single nucleotide polymorphism Unc-5 Family C-Terminal(UNC5CL) Candidate gene

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Living Arrangement of Older People: A Study of Community Living Elderly from Nepal

引用

Advances in Aging Research 2021年第6期10卷 133-142页

作者： Satya Narayan singh amrita Upadhyay Hom Nath Chalise Torrens University Sydney Australia Ask Foundation/Danphe Care Dillibazaar Kathmandu Nepal Mphil Lead PhD Program Central Department of Population Studies Tribhuvan University Kathmandu Nepal Population Association of Nepal Kathmandu Nepal

Background: Aging has caused changes in the structure of families that raises reflections on the sustainability of the traditional models of family care for older adults. The aim of this article is to analyze the situation of living arrangements of Nepalese older people. Methods: This study is a secondary analysis of structured interview data collected by the Central Department of Population Studies at Tribhuvan University (TU) via a cross-sectional survey of community-dwelling persons aged 60+ in the Pharping area of Kathmandu. For this study, there were 1326 valid responses. Results: Findings show over four-fifths of respondents (81.3%) were living with family members, far more than with a spouse only (11.6%), alone (6.2%), and others (0.9%). The proportion of Populace residing alone tends to increase with the increase in age of respondents;more widowers tend to live alone compared to those in marital unions;more elderly males without living children tend to live alone compared to those who have at least one living child. The sex of the respondents, marital status, ethnicity, income situation, and feeling of insecurity have significant differences in the living arrangement of older people in this study. Conclusion: Traditionally, Nepalese older adults are contented to live with their family members. The government of Nepal should promote the traditional living arrangements of older people through some incentives providing for family members taking care of their senior citizens.

关键词： Living Arrangements Older People of Nepal Care of Older People Social Security

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Feature-based augmentation and classification for tabular data

引用

CAAI Transactions on Intelligence Technology 2022年第3期7卷 481-491页

作者： Balachander Sathianarayanan Yogesh Chandra singh Samant Prahalad S.Conjeepuram Guruprasad Varshin B.Hariharan Nirmala Devi Manickam amrita School of Engineering Amrita Vishwa VidyapeethamCoimbatoreIndia

Generating synthetic samples for a tabular data is a strenuous *** of the time,the columns(features)in the dataset may not follow an ideal distribution *** objective of the proposed algorithm,Histogram Augmentation Technique(HAT),is to generate a dataset whose distribution is similar to that of the original *** augmentation is achieved based on individual columns,where separate algorithms are designed for continuous and discrete *** also use features of an object for *** humans make a judgement,they notice prominent features and characterise the perceived ***,conventional Machine Learning classifiers are designed and trained on the basis of *** the features as the basis for classification,Feature Importance Classifier(FIC)has been attempted in this *** treats every feature independent of each other,and ranks the features based on its dependence with the classified *** has been found that the FIC has the highest accuracy and has improved the accuracy by 5.54%on average,when it's compared to other *** suggested algorithms have been experimented on five datasets and compared with two augmentation algorithms and four state-of-the-art ML classification algorithms.

关键词： function classifier columns

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

流行和在旁遮普(印度) 的奶店动物的 Anaplasma marginale 感染的 haemato 生物化学的侧面

引用

Asian Pacific Journal of Tropical Medicine 2013年第2期6卷 161-166页

作者： Ashuma amrita Sharma Lachhman Das Singla Paramjit Kaur Mandeep singh Bal Balwinder Kaur Batth Prayag Dutt Juyal Department of Veterinary Parasitology College of Veterinary ScienceGuru Angad Dev Veterinary and Animal Sciences UniversityLudhiana-141004India Animal Disease Research Centre Guru Angad Dev Veterinary and Animal Sciences UniversityLudhiana-141004India

Objective:To do the systematic comparison of prevalence of anaplasmosis by PCR and Giemsa stained thin blood smear(GSTBS) based parasitological assays in dairy cattle of Punjab,which has not been reported *** analyse the haematobiochemical alterations in infected animals to arrive at the conclusion regarding the pathogenicity induced by Anaplasma marginale (***) in latent and patent ***:Study was conducted on 320 animals (236 cows,62 calves and 22 buffaloes) of Punjab,*** on genome of *** was performed by targeting msp1βgene using specific primers BAP-2/AL34S,amplifies products of size 407 *** based data on the characteristics of the infected animals and management strategies of the farm were collected and ***:Higher prevalence and more significant association was observed in the PCR based molecular diagnosis(P=0.00012) as compared to that in GSTBS(P=0.028 8) based diagnosis with various regions under *** respect to the regions,highest prevalence was recorded in Ferozepur by PCR based diagnosis, while that in Jalandhar by GSTBS *** marked significant association of the PCR based diagnosis with the age of the animals under study(P=0.00013) was observed elucidating no inverse age resistance to *** in cow *** profile of infected animals revealed marked anemia,liver dysfunction and increase globulin concentrate indicating rise in immunoglobulin level to counteract ***:PCR is far more sensitive in detecting the disease even in latent infection which may act as nidus for spread of anaplasmosis to susceptible animals in endemic *** of anaemia and liver dysfunction were comparable both in patent as well as latent infection indicating pathogenicity of both.

关键词： Anaplasmosis Dairy animals Haemato-biochemical Prevalence Polymerase chain reaction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Knowledge, attitude, and practice of techniques of breastfeeding among new mothers: A survey across Delhi Region

引用

Journal of Integrative Nursing 2022年第1期4卷 26-29页

作者： Himanshu VERMA Sirshti singh Nitika BAHUGUNA Mukul DAHIYA Jyoti SHAH Department of Otolaryngology Speech and Hearing UnitPGIMERChandigarhIndia Department of Swallowing Service Amrita Vishwa VidhyapeethamKollamKeralaIndia Department of Speech Pathology Sarthak Educational TrustNew DelhiIndia Ashtavakra Institute of Rehabilitation Sciences and Research DelhiIndia Speech-Swallowing and Hearing Care Clinic New DelhiIndia Department of Audiology and Speech-Pathology Saroj HospitalNew DelhiIndia

Objective:The present study aims to evaluate aims to assess the knowledge,attitude,and practice of primiparous mothers in the immediate postpartum period regarding breastfeeding techniques which will be helpful in forming awareness and training *** and Methods:A cross-sectional survey was used.A total of 120 primiparous mothers with a mean age of 24.92 years participated in the survey and filled the questionnaire related to the knowledge,attitude,and practice of techniques of ***:Results revealed that 48.3%of new mothers were not aware of the correct techniques to initiate breastfeeding,whereas 68.3%of subjects reported that during latching,the baby’s upper and lower lip should be *** majority of new mothers were aware of breastfeeding techniques with some misconceptions as in our culture,most of the breastfeeding information passed from generation to ***:The level of awareness about feeding skills among primiparous mothers can be further improved by antenatal counseling or training from health-care workers during the gestational *** will further help new mothers to educate and will provide adequate information which will decrease the myths.

关键词： Breastfeeding breastfeeding techniques lactation primiparous mother

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Methods for extracellular vesicle isolation from cancer cells

引用

Cancer Drug Resistance 2020年第3期3卷 371-384页

作者： Israa Salem Nicole M.Naranjo amrita singh Rachel DeRita Shiv Ram Krishn Luca S.Sirman Fabio Quaglia Alexander Duffy Nicholas Bowler Aejaz Sayeed Lucia R.Languino Department of Cancer Biology Sidney Kimmel Cancer CenterThomas Jefferson UniversityPhiladelphiaPA 19107USA. Astellas Institute for Regenerative Medicine MarlboroughMA 01752USA. School of Veterinary Medicine University of PennsylvaniaPhiladelphiaPA 19104USA. Baruch S.Blumberg Institute DoylestownPA 18902USA.

Cells are known to release different types of vesicles such as small extracellular vesicles(sEVs)and large extracellular vesicles(LEVs).sEVs and LEVs play important roles in intercellular communication,pre-metastatic niche formation,and disease progression;both can be detected cell culture media and biological *** and LEVs contain a variety of protein and RNA cargo,and they are believed to impact many biological functions of the recipient cells upon their internalization or binding to cell surface *** has recently been established that standard isolation techniques,such as differential ultracentrifugation,yield a mixed population of ***,density gradient ultracentrifugation has been reported to allow the isolation of sEVs without cellular ***,we describe the most common methods used to isolate sEVs from cell culture medium,mouse and human plasma,and a new technique for isolating sEVs from tissues as *** article also provides detailed procedures to isolate LEVs.

关键词： Extracellular vesicles differential ultracentrifugation iodixanol density gradient cell culture medium plasma tissue

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：