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Outcomes of Early Primary Endoscopic Realignment and Delayed Reconstruction in the Management of Posterior Urethral Injury in Male

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Journal of Biosciences and Medicines 2019年第10期7卷 1-16页

作者： Mohammad Nazmul Huda Prodyut Kumar Saha A. K. M. Shahidur Rahman Mohammad Ibrahim ali A. S. M. Humayun Kabir Munirunnessa Yeasmin Akter md. Mostafizur Rahmen Jannate Shaina Islam Nahid Kamal Department of Urology Dhaka Medical College Hospital (DMCH) Dhaka Bangladesh Department of Nephrology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh Department of Gynecology and Obstetrics Sir Salimullah Medical College & Mitford Hospital (SSMC & MH) Mitford Dhaka Bangladesh Department of Gynecology and Obstetrics Combined Military Hospital (CMH) Dhaka Bangladesh Department of Urology Medical College for Women & Hospital Uttara Dhaka Bangladesh Department of Pathology National Institute of Ophthalmology & Hospital Sher-E-Bangla Nagar Dhaka Bangladesh District Hospital Sherpur Bangladesh

Background: Posterior urethral injury usually occurs in male patients with pelvic fractures. Posterior urethral injuries are associated with considerable morbidity including urinary incontinence, erectile dysfunction and urethral stricture. Objective: To compare the outcomes between early primary endoscopic realignment and delayed reconstruction in the management of male patients of posterior urethral injury. Methodology: This prospective study was conducted in the department of urology and department of casualty, Dhaka Medical College Hospital, Dhaka, Bangladesh from July 2015 to June 2017 among 50 male patients with posterior urethral injury. Fifty patients were randomly allocated into two groups;the group A consisted of 24 patients underwent early primary endoscopic realignment within 10 days after posterior urethral injury and the group B consisted of 26 patients underwent delayed reconstruction in form of anastomotic urethroplasty after 3 months. All patients were followed up at 3rd, 6th and 9th month after the procedure. Outcome variables were post-operative urethral stricture, urinary incontinence and erectile dysfunction. Data were analyzed and compared by statistical tests. Results: The mean (±SD) age of the study patients was almost similar between the groups (28.8 ± 8.4 vs. 27.4 ± 7.2 years, p = 0.486). In group A, 83.33% patients developed postoperative urethral stricture, none of them developed urinary incontinence and 20.83% developed erectile dysfunction;On the other hand, in group B, these rates were 38.46%, 23.07% and 38.46% respectively. Postoperative urethral stricture formation was significantly higher in Group A (p = 0.0012) but urinary incontinence and erectile dysfunction rates were significantly higher in Group B (p = 0.018 and p = 0.042 respectively). Conclusion: Early primary endoscopic realignment is better than delayed reconstruction in the management of male patients with posterior urethral injury. It provides less postoperative complica

关键词： Endoscopic Realignment Erectile Dysfunction Urinary Incontinence Urethral Injury Urethral Stricture

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红花籽粕对小鼠的急性毒性及抗溃疡性结肠炎作用研究

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中草药 2024年第8期55卷 2601-2610页

作者：戚曼王文萱付向磊姜超张亮 md.HASAN ali 李剑楚生辉刘敏石河子大学药学院新疆植物药资源利用教育部重点实验室新疆石河子832003 华东理工大学药学院生物反应器工程国家重点实验室上海200000

目的评价红花籽粕(红花Carthamus tinctorius的种子经过压榨提取红花籽油后的副产品)对小鼠的急性毒性及抗溃疡性结肠炎(ulcerative colitis,UC)作用。方法C57BL/6小鼠ig不同剂量的红花籽粕,7 d后计算脏器指数,采用苏木素-伊红(HE)染色... 详细信息

目的评价红花籽粕(红花Carthamus tinctorius的种子经过压榨提取红花籽油后的副产品)对小鼠的急性毒性及抗溃疡性结肠炎(ulcerative colitis,UC)作用。方法C57BL/6小鼠ig不同剂量的红花籽粕,7 d后计算脏器指数,采用苏木素-伊红(HE)染色观察肝、脾、肾组织病理变化,测定血清中肝功能、肾功能及血脂水平,以评价红花籽粕的急性毒性。建立葡聚糖硫酸钠(dextran sulphate sodium,DSS)诱导的UC小鼠模型,每天记录小鼠体质量,测定疾病活动指数(disease activity index,DAI)评分、结肠长度以及脏器指数,采用HE染色和阿利新蓝-过碘酸雪夫(AB-PAS)染色评价结肠组织病理学变化,采用qRT-PCR和Western blotting检测结肠组织中炎症和黏膜屏障相关因子表达。结果急性毒性实验中,与对照组比较,红花籽粕组小鼠脏器指数、血液生化指标没有显著差异,脏器病理切片也未见异常。红花籽粕对DSS诱导的UC小鼠具有较好的保护作用,可以显著改善体质量减轻、DAI评分升高、结肠长度缩短等临床症状(P<0.01),减轻结肠组织病理损伤,抑制肠道炎症细胞的浸润,保护杯状细胞,提高紧密连接蛋白和黏蛋白的表达(P<0.05、0.01、0.001),改善肠道屏障完整性。结论红花籽粕具有较高的安全性,且对DSS诱导的UC小鼠具有显著的治疗作用。

关键词：红花籽粕急性毒性溃疡性结肠炎炎症肠道屏障

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Unveiling the Predictive Capabilities of Machine Learning in Air Quality Data Analysis: A Comparative Evaluation of Different Regression Models

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Open Journal of Air Pollution 2023年第4期12卷 142-159页

作者： Mosammat Mustari Khanaum md.Saidul Borhan Farzana Ferdoush Mohammed ali Nause Russel Mustafa Murshed Department of Civil Construction and Environmental Engineering North Dakota State University Fargo USA Texas Department of Transportation Maintenance Division Austin USA Department of Arts and Sciences Ahsanullah University of Science and Technology Dhaka Bangladesh School of Social & Environmental Sustainability University of Glasgow Glasgow UK Department of Economics Andrew Young School of Policy Studies Georgia State University Atlanta USA

Air quality is a critical concern for public health and environmental regulation. The Air Quality Index (AQI), a widely adopted index by the US Environmental Protection Agency (EPA), serves as a crucial metric for reporting site-specific air pollution levels. Accurately predicting air quality, as measured by the AQI, is essential for effective air pollution management. In this study, we aim to identify the most reliable regression model among linear discriminant analysis (LDA), quadratic discriminant analysis (QDA), logistic regression, and K-nearest neighbors (KNN). We conducted four different regression analyses using a machine learning approach to determine the model with the best performance. By employing the confusion matrix and error percentages, we selected the best-performing model, which yielded prediction error rates of 22%, 23%, 20%, and 27%, respectively, for LDA, QDA, logistic regression, and KNN models. The logistic regression model outperformed the other three statistical models in predicting AQI. Understanding these models' performance can help address an existing gap in air quality research and contribute to the integration of regression techniques in AQI studies, ultimately benefiting stakeholders like environmental regulators, healthcare professionals, urban planners, and researchers.

关键词： Regression Analysis Air Quality Index Linear Discriminant Analysis Quadratic Discriminant Analysis Logistic Regression K-Nearest Neighbors Machine Learning Big Data Analysis

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Zoonotic human liver flukes,a type 1 biocarcinogen,in freshwater fishes:genetic analysis and confirmation of molluscan vectors and reservoir hosts in Bangladesh

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Infectious Diseases of Poverty 2024年第3期13卷 73-88页

作者： Sharmin Shahid Labony md.Abdul alim Muhammad Mehedi Hasan md.Shahadat Hossain Sharmin Akter Joydeep Paul Thahsin Farjana md.Haydar ali Mohammad Zahangir Alam Takeshi Hatta Hayato Kawada Keiko Mizutani Naotoshi Tsuji null Anisuzzaman Department of Parasitology Faculty of Veterinary ScienceBangladesh Agricultural UniversityMymensingh 2202Bangladesh Department of Fisheries Technology Faculty of FisheriesBangladesh Agricultural UniversityMymensingh 2202Bangladesh Department of Biotechnology School of Life Sciences&BiotechnologyAdamas UniversityBarasat-Barrackpore RdJagannathpurKolkataWest Bengal 700126India Department of Pathology and Parasitology Hajee Mohammad Danesh Science and Technology UniversityDinajpur 5200Bangladesh Department of Parasitology and Tropical Medicine Kitasato University School of Medicine1-15-1 KitasatoMinamiSagamiharaKanagawa 252-0374Japan Department of Molecular and Cellular Parasitology Kitasato University Graduate School of Medical Sciences1-15-1 KitasatoMinamiSagamiharaKanagawa 252-0373Japan

Background Opisthorchiid flukes,particularly Opisthorchis viverrini,Opisthorchis felineus,Clonorchis sinensis,and Metorchis *** the most common fish-borne zoonotic human liver flukes(hLFs).Liver fluke infections are more prevalent in resource-deprived and underprivileged *** herein estimated the prevalence of the metacercariae(MC)of major hLFs in common large freshwater fishes(lFWF)marketed for human consumption from some selected areas of Bangladesh along with detection of their molluscan vectors and *** The current status of fish-borne zoonotic hLF infections in lFWF was investigated along with their molluscan vectors and mammalian reservoir hosts in Mymensingh and Kishoreganj in Bangladesh from July 2018-June 2022 using conventional and multiple molecular techniques,such as PCR,PCR-restriction fragment length polymorphism(RFLP),sequencing,and bioinformatic *** infection rate of fishes was analyzed using the Z-test and the loads of MC were compared using the chi-squared(χ^(2))*** The MC of ***,Opisthorchis spp.,and Metorchis *** detected in 11 species of common and popular *** lFWF,the estimated prevalence was 18.7%and the mean load was 137.4±149.8 MC per 100 g of *** prevalence was the highest(P0.05)distributed between the head and body of *** infection rate was slightly higher in cultured(19.6%)*** MC of ***,***,***,and Metorchis orientalis in fishes were confirmed using PCR,PCR-RFLP and *** cercariae of opisthorchiid(Pleurolophocercus cercariae)flukes were only recovered from Bithynia spp.(3.9%,42 out of 1089).The ova of hLFs from dogs(4.3%,5 out of 116)and cats(6.0%,6 out of 100),and adult flukes(***)from ducks(41.1%113 out of 275)were *** The MC of

关键词： Human liver fluke Freshwater fish Molluscan vector Reservoir host Bangladesh

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起始联合降脂策略对心内科门诊“极高危ASCVD”患者疗效及安全性观察——真实世界的前瞻性队列研究

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中国临床药理学与治疗学 2024年第8期29卷 907-916页

作者：赵震宇李媛郭宇轩毛萧萧 md.Sayed ali Sheikh 夏珂中南大学湘雅医院临床药理研究所中南大学湘雅医院心血管内科湖南长沙410008 Internal Medicine Department CardiologyCollege of MedicineJouf UniversitySakaka 72388Saudi Arabia

目的:在真实世界的前瞻性队列研究中观察心内科门诊“极高危ASCVD”患者在治疗起始阶段采用联合降脂策略的疗效与安全性。方法:连续入组2021年1月至6月在湘雅医院心内科高脂血症专病门诊就诊的“极高危ASCVD”患者,根据其实际降脂策略... 详细信息

目的:在真实世界的前瞻性队列研究中观察心内科门诊“极高危ASCVD”患者在治疗起始阶段采用联合降脂策略的疗效与安全性。方法:连续入组2021年1月至6月在湘雅医院心内科高脂血症专病门诊就诊的“极高危ASCVD”患者,根据其实际降脂策略分为三组:阿托伐他汀单药组;阿托伐他汀联合依折麦布组;阿托伐他汀联合依洛尤单抗组。主要观察终点为治疗一个月后低密度脂蛋白胆固醇(LDL-C)、脂蛋白a[Lp(a)]、非-HDL-C变化,次要终点为总胆固醇(TC)、甘油三酯(TG)、LDL-C、超敏C反应蛋白(hs-CRP)变化及安全性指标。结果:无论哪种联合方式,在“极高危ASCVD”患者降脂起始阶段联合降脂治疗的疗效均显著优于阿托伐他汀单药组:LDL-C、Log[Lp(a)]、非-HDL-C、TC的降幅更大,差异均有统计学意义(均P0.05)。以“LDL-C<1.4 mmol/L或<1.8 mmol/L”作为降脂达标的标准时,两组联合降脂治疗的LDL-C达标率均高于阿托伐他汀单药组,差异均有统计学意义(均P<0.05);阿托伐他汀联合依洛尤单抗组的LDL-C达标率高于阿托伐他汀联合依折麦布组,差异均有统计学意义(均P<0.05)。单独或联合“LDL下降超过50%”的降幅为达标标准,三组均无人能达标。治疗后三组间的肝脏转氨酶水平变化差异均无统计学意义(均P<0.05);三组间心肌酶同工酶(CK-MB)均下降,但差异无统计学意义(P<0.05)。与阿托伐他汀单药组相比,两联合降脂组治疗组的血糖均下降,差异具有统计学意义(P<0.05);阿托伐他汀联合依折麦布组的血糖比阿托伐他汀联合依洛尤单抗组的降幅更大,差异有统计学意义(P<0.05)。结论:起始联合降脂治疗1个月对心内科门诊“极高危ASCVD”患者的降脂效果及LDL-C的达标率优于阿托伐他汀单药组。以LDL-C<1.4 mmol/L或<1.8 mmol/L为降脂达标目标时,阿托伐他汀联合依洛尤单抗组治疗1个月后LDL-C达标率高于联合依折麦布组;以“LDL下降超过50%”的降幅作为降脂达标标准时,1个月内很难达标。门诊“极高危ASCVD”患者采用起始联合的降脂治疗1个月无不良反应。起始联合降脂策略可用于心内科门诊“极高危ASCVD”患者中LDL-C数值需早期达标的人群,阿托伐他汀联合依洛尤单抗可用于需在1个月内LDL-C<1.4 mmol/L或<1.8 mmol/L的人群。

关键词：起始联合降脂极高危ASCVD 真实世界前瞻性队列研究早期达标

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Hybrid Prediction Method for Solar Power Using Different Computational Intelligence Algorithms

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Smart Grid and Renewable Energy 2013年第1期4卷 76-87页

作者： md.Rahat Hossain Amanullah Maung Than Oo A. B. M. Shawkat ali Power Engineering Research Group (PERG) Central Queensland University Rockhampton Australia.

Computational Intelligence (CI) holds the key to the development of smart grid to overcome the challenges of planning and optimization through accurate prediction of Renewable Energy Sources (RES). This paper presents an architectural framework for the construction of hybrid intelligent predictor for solar power. This research investigates the applicability of heterogeneous regression algorithms for 6 hour ahead solar power availability forecasting using historical data from Rockhampton, Australia. Real life solar radiation data is collected across six years with hourly resolution from 2005 to 2010. We observe that the hybrid prediction method is suitable for a reliable smart grid energy management. Prediction reliability of the proposed hybrid prediction method is carried out in terms of prediction error performance based on statistical and graphical methods. The experimental results show that the proposed hybrid method achieved acceptable prediction accuracy. This potential hybrid model is applicable as a local predictor for any proposed hybrid method in real life application for 6 hours in advance prediction to ensure constant solar power supply in the smart grid operation.

关键词： Computational Intelligence Heterogeneous Regressions Algorithms Performance Evaluation Hybrid Method Mean Absolute Scaled Error (MASE)

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PCSK9与脑胆固醇稳态及阿尔茨海默病的潜在关联

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医药导报 2021年第6期40卷 773-775页

作者：李媛赵震宇 md.Sayed ali Sheikh 胡涛夏珂中南大学湘雅医院心血管内科长沙421008 中南大学湘雅医院临床药理研究所长沙421008 阿尔苏夫医科大学心血管内科沙特阿拉伯2014

前蛋白转化酶枯草杆菌蛋白酶kexin9型(PCSK9)抑制剂在血脂管理中备受关注,而PCSK9与脑胆固醇稳态及阿尔茨海默病(AD)的潜在关联鲜为人知。研究显示脑胆固醇依赖原位合成且AD患者脑脊液中PCSK9水平升高,但PCSK9不能穿过血-脑屏障。该文... 详细信息

前蛋白转化酶枯草杆菌蛋白酶kexin9型(PCSK9)抑制剂在血脂管理中备受关注,而PCSK9与脑胆固醇稳态及阿尔茨海默病(AD)的潜在关联鲜为人知。研究显示脑胆固醇依赖原位合成且AD患者脑脊液中PCSK9水平升高,但PCSK9不能穿过血-脑屏障。该文将阐述PCSK9参与脑胆固醇稳态及AD的可能机制及作用靶点,并进一步探讨PCSK9抑制剂在心血管领域的应用是否对患者神经认知功能产生影响。

关键词：前蛋白转化酶枯草杆菌蛋白酶kexin9型抑制剂脑胆固醇稳态阿尔茨海默病神经认知功能

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Do osteoporosis-related vertebral fractures precede hip fractures?

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World Journal of Orthopedics 2012年第12期3卷 235-238页

作者： Mir Sadat-ali Abid Hussain Gullenpet md.Quamar Azam Ammar K Al-Omran Department of Orthopaedic Surgery College of Medicine University of Dammam and King Fahd Hospital of the University Al Khobar 31952 Saudi Arabia Department of Radiology College of Medicine University of Dammam and King Fahd Hospital of the University Al Khobar 31952 Saudi Arabia

AIM:To evaluate the relationship between a vertebral fracture and a hip fracture in Saudi Arabians with ***:In this retrospective study,154 Saudi Arabian patients with osteoporosis-related hip fractures were analyzed for the presence of a vertebral *** were retrieved from the IPAC(Image Picture Archiving and Computing)System,an imaging retrieval system,and were reviewed independently by two of the authors,Abid Hussain Gullenpet,and Mir Sadat-ali,and later reviewed *** admitted with proximal hip fracture who were≥50 years and had undergone Thoraco-lumber imaging and a dual energy X-ray absorptiometry(DEXA)scan were included in the *** with a history of significant trauma to the spine and those with a malignancy or connective tissue disorder were excluded from the ***:Out of 154 patients with hip fractures,78had a fracture of the femoral neck while 76 had an intertrochanteric hip *** the 111 patients whowere finally included in the study,after applying inclusion and exclusion criteria,76 patients with an average age of 67.28±12 years had no fractures of the ***-five patients with an average age of 76.9±14.5years(31.53%)had a total of 49 vertebral *** with vertebral fractures were significantly older than those without fractures P<***,24.7%of these patients had an asymptomatic vertebral *** analysis showed that 11 males(18.96%)and 24 females(45.28%)had suffered a previous asymptomatic vertebral ***,all women who participated in this study and who presented with a femoral neck fracture had experienced a prior asymptomatic vertebral ***:We recommend that all elderly patients who go to the radiology department for a chest X-ray also have a DEXA scan and a lateral thoracic spine radiograph.

关键词： Fragility fracture Osteoporosis Vertebral fractures Hip fractures Saudi Arabia

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氧等离子体处理对涤纶织物数码转移印花的作用

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现代纺织技术 2020年第2期28卷 70-75,84页

作者： md.ali Hossain 陈维国王成龙金淑兰吴浩张亚浙江理工大学生态染整技术教育部工程研究中心杭州310018 金华洁灵家居用品有限公司浙江金华321037

为了研究低温等离子体处理对涤纶织物数码转移印花的影响,采用扫描电子显微镜(SEM)观察,发现了经等离子体处理的涤纶纤维表面被明显刻蚀,使纤维表面产生大量的细微凹孔;通过X-光电子能谱(XPS)分析,揭示了经等离子体处理的涤纶纤维表面... 详细信息

为了研究低温等离子体处理对涤纶织物数码转移印花的影响,采用扫描电子显微镜(SEM)观察,发现了经等离子体处理的涤纶纤维表面被明显刻蚀,使纤维表面产生大量的细微凹孔;通过X-光电子能谱(XPS)分析,揭示了经等离子体处理的涤纶纤维表面含氧化学基团有所增加;同时,接触角测试表明等离子体处理的涤纶织物润湿性有了明显的提升。显然,氧等离子体中高能粒子的撞击导致涤纶纤维表面大分子链发生部分降解,表现为处理后涤纶纤维表面粗糙度的提高,使得纤维比表面积提高,增加了热转移印花中分散染料在纤维表面的富集和染着,而纤维表面粗糙度的增加也改变了纤维表面的光反射特征,进而又促进了涤纶织物转移印花得色率的提高。热重分析(TG)表明等离子体对涤纶织物造成的损伤非常小,甚至低于热转移过程本身造成对纤维的损伤。所以,等离子体处理可以作为涤纶织物数码转移印花的前处理,以减少分散染料墨水的消耗。

关键词：等离子体数码转移印花涤纶织物表面改性表面粗糙度

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Evaluation and comparison of CMIP6 models and MERRA-2 reanalysis AOD against Satellite observations from 2000 to 2014 over China

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Geoscience Frontiers 2022年第2期13卷 165-185页

作者： md.Arfan ali Muhammad Bilal Yu Wang Zhongfeng Qiu Janet E.Nichol Gerrit de Leeuw Song Ke Alaa M.hawish Mansour Almazroui Usman Mazhar Birhanu Asmerom Habtemicheal M.Nazrul Islam Lab of Environmental Remote Sensing(LERS) School of Marine SciencesNanjing University of Information Science and TechnologyNanjing 210044China Department of Geography School of Global StudiesUniversity of SussexBrighton BN19RHUK Royal Netherlands Meteorological Institute(KNMI) R&D Satellite Observations3730AE De BiltThe Netherlands School of Atmospheric Physics Nanjing University of Information Science and TechnologyNanjing 210044China Aerospace Information Research Institute Chinese Academy of Sciences(AirCAS)No.20 Datun RoadChaoyang DistrictBeijing 100101China School of Environment Science and Spatial Informatics University of Mining and TechnologyXuzhouJiangsu 221116China Geological Survey of Jiangsu Province Nanjing 210018China Center of Excellence for Climate Change Research/Department of Meteorology King Abdulaziz UniversityJeddah 21589Saudi Arabia Climatic Research Unit School of Environmental SciencesUniversity of East AngliaNorwichUK School of Remote Sensing and Geomatics Engineering Nanjing University of Information Science and TechnologyNanjing 210044China Department of Physics Wollo UniversityDessie P.O.Box 1145Ethiopia

Rapid industrialization and urbanization along with a growing population are contributing significantly to air pollution in *** of long-term aerosol optical depth(AOD)data from models and reanalysis,can greatly promote understanding of spatiotemporal variations in air pollution in *** do this,AOD(550 nm)values from 2000 to 2014 were obtained from the Coupled Model Intercomparison Project(CIMP6),the second version of Modern-Era Retrospective analysis for Research,and Applications(MERRA-2),and the Moderate Resolution Imaging Spectroradiometer(MODIS;flying on the Terra satellite)combined Dark Target and Deep Blue(DTB)aerosol *** used the TerraMODIS DTB AOD(hereafter MODIS DTB AOD)as a standard to evaluate CMIP6 Ensemble AOD(hereafter CMIP6 AOD)and MERRA-2 reanalysis AOD(hereafter MERRA-2 AOD).Results show better correlations and smaller errors between MERRA-2 and MODIS DTB AOD,than between CMIP6 and MODIS DTB AOD,in most regions of China,at both annual and seasonal ***,significant under-and over-estimations in the MERRA-2 and CMIP6 AOD were also observed relative to MODIS DTB *** long-term(2000-2014)MODIS DTB AOD distributions show the highest AOD over the North China Plain(0.71)followed by Central China(0.69),Yangtse River Delta(0.67),Sichuan Basin(0.64),and Pearl River Delta(0.54)*** lowest AOD values were recorded over the Tibetan Plateau(0.13±0.01)followed by Qinghai(0.19±0.03)and the Gobi Desert(0.21±0.03).Large amounts of sand and dust particles emitted from natural sources(the Taklamakan and Gobi Deserts)may result in higher AOD in spring compared to summer,autumn,and *** were also calculated for 2000-2005,for2006-2010(when China introduced strict air pollution control policies during the 11 th Five Year Plan or FYP),and for 2011-2014(during the 12 th FYP).An increasing trend in MODIS DTB AOD was observed throughout the country during *** uncontrolled industrialization,urbanization,and rapid eco

关键词： Aerosol Optical Depth Air pollution MERRA-2 MODIS Air quality

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