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Symptomatic COVID-19 in University Students: A School-Wide Web-Based Questionnaire Survey during the Omicron Variant Outbreak

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Advances in Infectious Diseases 2024年第1期14卷 133-146页

作者： Mai Kitahara Hisami Sameshima Rie Tanuma Kumi Setoyama Yuka Yamaguchi Akiyo Kamachi Satoko Nakamura mayuko sakuma Yoichi Kawaike Tamotsu Furuya Shinji Ijichi Health Service Center Kagoshima University Kagoshima Japan Center for Management of Information Technologies Kagoshima University Kagoshima Japan

Aim: To detect risk and preventive factors associated with the Omicron variant infection in university students, a combination of a web-based survey and multivariate logistic regression analysis was introduced as the front-line initiatives by the school health practitioners. Design: Questionnaire survey. Methods: The school-wide web-based questionnaire survey was conducted among our university students as a part of the annual health check-up in April, 2023. The positive outcome was confined to the first symptomatic COVID-19 onset during the Omicron variant outbreak. Results: In this self-administered survey, risk or protective associations were merely estimated statistically in university students (n = 5406). In measured factors, karaoke and club/group activities could maintain the statistical significance in adjusted odds ratios (ORs) as relative risk factors, and science course, measles/ rubella (MR) vaccination, and COVID-19 vaccination remained as relative protective factors in adjusted OR analyses. Club/group activities with member gathering and karaoke sing-along sessions in university students may frequently have WHO’s three Cs. These risk factors are still important topics for the infection control of COVID-19 in university students. Together with some recent reports from other researchers, the significant protective role of MR vaccine in our survey warrants further clinical investigation. If the breakthrough infection continuously constitutes the majority of infection, real data in test-negative case-control or web-based questionnaire design continue to be important for statistical analysis to determine the minimal requirement of our strategies which may be equivalent to or replace COVID-19 vaccines.

关键词： Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Coronavirus Disease 2019 (COVID-19) Omicron Variant Risk Behaviors Protective Factors

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Symptomatic COVID-19 in University Students: A School-Wide Web-Based Questionnaire Survey during the Omicron Variant Outbreak

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Advances in Infectious Diseases（传染病进展） 2024年第1期 133页

作者： Mai Kitahara Hisami Sameshima Rie Tanuma Kumi Setoyama Yuka Yamaguchi Akiyo Kamachi Satoko Nakamura mayuko sakuma Yoichi Kawaike Tamotsu Furuya Shinji Ijichi

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Pneumoparotid with imaging findings:A case report and review of literature

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World Journal of Clinical Cases 2024年第34期12卷 6705-6714页

作者： Wakako Kubota Makiko Kyan-Onodera Yasuomi Fujimoto Akihiro sakuma Ryuji Katada Chihiro Sugiura Department of Radiology Sapporo Tokushukai HospitalSapporo 0040041HokkaidoJapan Department of Dentistry and Oral Surgery Sapporo Tokushukai HospitalSapporo 0040041HokkaidoJapan

BACKGROUND Pneumoparotid is a rare disease associated with retrograde airflow into the ductal *** is no established treatment for this disease,which has no known *** puffing and playing wind instruments are known to be the causes of this *** SUMMARY We managed a case,in which pneumoparotid suddenly recurred 4 months after surgery for purulent *** patient did not report any obvious etiological factors,such as mouth puffing or playing a wind *** reviewed 128 articles(from 1941 to 2023)that reported on a total of 166 patients with pneumoparotid,including the patient from the present case report,with imaging *** is the first reported case of pneumoparotid following surgery for purulent *** etiology in our case was classified as *** Imaging findings could be sufficient for accurate pneumoparotid diagnoses and the exclusion of complications;computed tomography could be useful.

关键词： Computed tomography Imaging findings Parotid gland Pneumoparotid Pneumoparotitis Case report

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Role of the STRIPAK complex and the Hippo pathway in synaptic terminal formation

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Neural Regeneration Research 2017年第4期12卷 578-579页

作者： Chisako sakuma Takahiro Chihara Department of Tropical Medicine Center for Medical EntomologyThe Jikei University School of Medicine Department of Biological Science Graduate School of ScienceHiroshima University

To transmit neural information from pre to postsynaptic neu- rons, the number, morphology, and function of the synapse have to be strictly regulated. Failures in synaptic formations are linked to neural disorders. For example, it is suggested that localization of N-methyl-D-aspartate （NMDA） receptors plays important roles in NMDA receptor-induced excitotoxicity, which is in turn thought to contribute to cell death associated with certain neurodegenerative diseases （Parsons and Ray-mond, 2014）. Furthermore, synaptic overgrowth is observed in Drosophila dfmrl （homolog of mammalian FMRI） gene mu- tant, which causes the Fragile X syndrome （Zhang et al., 2001）.

关键词： Hippo synaptic formations transmit localization NMDA aspartate homolog excitatory dynamically

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On-chip 3D rotation of oocyte based on a vibration-induced local whirling flow

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Microsystems & Nanoengineering 2015年第1期1卷 150-158页

作者： Takeshi Hayakawa Shinya sakuma Fumihito Arai Department of Micro-Nano Systems Engineering Nagoya UniversityNagoya-CityAichi-Pref.JAPAN

We propose a novel on-chip 3D cell rotation method based on a vibration-induced *** circular vibration is applied to a microchip with micropillar patterns,a highly localized whirling flow is induced around the *** direction and velocity of this flow can be controlled by changing the direction and amplitude of the applied ***,this flow can be induced on an open chip *** this study,we adopted a microchip with three micropillars arranged in a triangular configuration and an xyz piezoelectric actuator to apply the circular *** the centre of the micropillars,the interference of the vibration-induced flows originating from the individual micropillars induces rotational ***,a biological cell placed at this centre rotates under the influence of the *** three-plane circular vibrations in the xy,xz or yz plane,the cell can rotate in both the focal and vertical planes of the *** this 3D cell rotation method,we measured the rotational speeds of mouse oocytes in the focal and vertical planes as 63.7±4.0°s^(−1) and 3.5±2.1°s^(−1),***,we demonstrated the transportation and rotation of the mouse oocytes and re-positioned their nuclei into a position observable by microscope.

关键词： lab on a chip cell manipulation vibration-induced flow acoustic streaming

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Role of atomic-scale thermal fluctuations in the coercivity

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npj Computational Materials 2020年第1期6卷 1084-1090页

作者： Yuta Toga Seiji Miyashita Akimasa sakuma Takashi Miyake National Institute for Materials Science(NIMS) Tsukuba 305-0047Japan Elements Strategy Initiative Center for Magnetic Materials(ESICMM) TsukubaJapan Institute for Solid State Physics University of TokyoKashiwa 277-8581Japan The Physical Society of Japan Tokyo 113-0033Japan Department of Applied Physics Tohoku UniversitySendai 980-8579Japan National Institute of Advanced Industrial Science and Technology(AIST) Tsukuba 305-8568Japan

The microscopic mechanism of coercivity at finite temperature is a crucial issue for permanent *** we present the temperature dependence of the coercivity of an atomistic spin model for the highest-performance magnet Nd_(2)Fe_(14)*** quantitative analysis of the magnetization reversal with thermal fluctuations,we focus on the free energy landscape as a function of the *** free energy is calculated by the replica-exchange Wang–Landau *** approach allows us to address a slow nucleation problem,i.e.,thermal activation effects,in the magnetization *** concretely observed that the thermal fluctuations lead to a downward convexity in the coercivity concerning the ***,through analyzing the microscopic process of the thermal activation(nucleation),we discover the activation volume is insensitive to a magnetic field around the *** insensitivity explains the linear reduction of the free energy barrier by the magnetic field in the nucleation process.

关键词： thermal activation magnetization

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Optimal Total Sleep Duration per Day to Maintain Health-Related Quality of Life in Male Collegiate Athletes:A Cross-Sectional Study

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Journal of Science in Sport and Exercise 2023年第4期5卷 360-368页

作者： Yuko Morita Taeko Sasai-sakuma Institute of Arts and Sciences Tokyo University of Science6-3-1NiijukuKatsushika-kuTokyo 125-8585Japan Department of Clinical Laboratory Science Faculty of Medical TechnologyTeikyo University2-11-1KagaItabashi-kuTokyo 173-8605Japan

Purpose This study investigated the optimal total sleep duration per day required by collegiate athletes to maintain the physical and mental health-related quality of life(HRQOL),compared with non-athlete *** In this cross-sectional study,a questionnaire survey was conducted to assess demographic variables,lifestyle and sleep habits,and HRQOL in 392 collegiate students(non-athletes,n=174;athletes,n=218).Physical component summary(PCS)and mental component summary(MCS)were assessed using the short-form-8 health *** with both good PCS and MCS were defined as having a good *** confirm an association between the total sleep duration per day and good HRQOL,logistic regression analyses were conducted in non-athlete students and collegiate athletes ***,receiver-operating curve(ROC)analyses were performed for the detection of the cut-off point of total sleep duration per day sufficient to maintain a good *** The average total sleep duration per day was 7 h 19 min for collegiate athletes,and 78.9%of them had a worse *** cut-off point of total sleep duration per day to maintain good HRQOL for collegiate athletes was 7.92 h(area under ROC,0.64;P=0.038;sensitivity,75.4%;specificity,57.9%),which was longer than 6.79 h for non-athlete *** Collegiate athletes required longer nocturnal sleep than non-athlete ***,their habitual nocturnal sleep duration was shorter compared to their optimal duration;around 70%of them faced chronic insufficient *** sleep habits and sleep education is important in maintaining their good health-related quality of life.

关键词： Athlete Sleep duration Health-related quality of life Insufficient sleep

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Exploitation of shape memory alloy actuator using resistance feedback control and its development

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Progress in Natural Science:Materials International 2010年第1期20卷 97-103页

作者： Hiroki CHO Takaei YAMAMOTO Yuji TAKEDA Akihiko SUZUKI Toshio sakuma Faculty of Engineering Oita University700 DannoharuOita 870-1192Japan TAKE R&D 2-7-27UmedaKasukabeJapan

The relationship between phase transformation and electric resistivity of Ti-42.6Ni-7Cu SMA was *** the isothermal tensile tests,stress-strain curve shows large hysteresis and nonlinearity,whereas the resistivity-strain curve can be fitted by *** resistivity of SMAs can be determined from the volume fractions of the martensitic and austenitic *** characteristics leads to that the resistance of the SMAs is used as a parameter of strain of SMAs.A SMA actuator using resistance feedback control system was proposed,which can control and retain positioning at any positions without using sensor devices,and the deviation of position of this system was less than 3 μm.

关键词： Ti-Ni-Cu alloy shape memory alloy resistivity shape memory characteristics phase transformation

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Dietary Control of Lactase Expression in the Weaning Rat

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Biomedical and Environmental Sciences 1996年第2期9卷 181-184页

作者： K．sakuma Y．WATANBE 等 DepartmentofMolecularNutrition KagawaNutritionUriversitySakadoSaitama350－02Japan DepartmentofMolec

The decline in lactase activity during weaning has been well established. However, its molecuIar mechanism remains to be explored. We studied changes in the expression of lactase in terms of the transcription and translation processes in rat microvillus membrane by Northern blot and Western blot analysis, respectively. To examine the effect of dietary change from a milk to a non-milk diet on the developmental pattern of lactase expression, weaning was prevented by keeping the rats under suckling conditions for 27 days after birth. This treatment only suppressed the extent of decline: while the weanlings showed 17 percent activity compared to that of 4-day-old rats, the prolonged suckling rats showed only 42 percent. The changes in the expression of lactase mRNA and protein were parallel with the change of lactase activity. In other words, the fundamental pattern of significant depression of lactase expression occurred relatively independent of dietary *** observation indicates that the regulation of lactase expression is firmly determined at the transcriptional level, and that dietary factor such as the termination of lactose ingestion has only a relatively minor effect

关键词： Dietary Control of Lactase Expression in the Weaning Rat

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Microstructural evolution in Al-Zn eutectoid alloy by hot-rolling

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Transactions of Nonferrous Metals Society of China 2014年第7期24卷 2107-2111页

作者： Toshiaki MANAKA Goroh ITOH Yoshinobu MOTOHASHI Takaaki sakuma School of Science and Engineering Ibaraki University College of Engineering Ibaraki University

The Al-Zn eutectoid alloy has been widely known as a typical superplastic metallic material, where fine-grained microstructure is usually obtained by heat treatment. Recently, thermo-mechanical controlled process has also been reported to provide a fine-grained microstructure. In the present study, Al-Zn alloy ingots of 20 mm in thickness were homogenized and hot-rolled to a thickness of 2 mm under three processes： 1） the specimen was air-cooled after homogenization and hot-rolled; 2） the specimen was water-quenched after homogenization and hot-rolled; 3） the specimen was immediately hot-rolled after homogenization. Microstructural observation showed that, in processes l and 3, lamellar microstructure was formed after homogenization, and became fragmented to fine-grained microstructure as the hot roiling process proceeded. In process 2, fine-grained microstructure without lamellar microstructure was attained throughout the hot-rolling process. A minimum grain size of 1.6 μm was obtained in process 3. Tensile tests at room temperature showed that the elongation to failure was the largest in process 3.

关键词： aluminum-zinc alloy eutectoid microstructure control hot-rolling superplastic material

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