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Recent antibacterial agents from biomass derivatives:Characteristics and applications

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Journal of Bioresources and Bioproducts 2024年第3期9卷 283-309页

作者： Nissa Nurfajrin Solihat Alif Faturahman Hidayat R.A.Ilyas Senthil muthu Kumar Thiagamani Nur Izyan Wan Azeele Fahriya Puspita Sari maya Ismayati mohammad Irfan Bakshi Zaharaddeen N.Garba m.Hazwan Hussin Witta Kartika Restu Wasrin Syafii Harits Atika Ariyanta Widya Fatriasari Research Center for Biomass and Bioproducts National Research and Innovation Agency(BRIN)Kawasan KST SoekarnoJl Raya Bogor KM 46 Cibinong Bogor 16911Indonesia Department of Bioproducts and Biosystems School of Chemical EngineeringAalto UniversityEspoo 16300Finland Department of Chemical Engineering Faculty of Chemical and Energy EngineeringUniversiti Teknologi MalaysiaJohor 81310Malaysia Centre for Advanced Composite materials Universiti Teknologi MalaysiaJohor 81310Malaysia Institute of Tropical Forestry and Forest Products Universiti Putra MalaysiaSerdang 43400Malaysia Centre of Excellence for Biomass Utilization Universiti Malaysia PerlisPerlis 02600Malaysia Department of mechanical Engineering Kalasalingam Academy of Research and EducationKrishnankoil 626126India Institute of Bioproduct Development(IBD) Universiti Teknologi MalaysiaJohor 81310Malaysia Department of Chemistry Ahmadu Bello UniversityZaria 810211Nigeria materials Technology Research Group(maTReC) School of Chemical SciencesUniversiti Sains MalaysiaMinden 11800Malaysia Research Center for Chemistry National Research and Innovation Agency(BRIN)Kawasan Puspiptek SerpongSouth Tangerang 15314Indonesia Department of Forest Products Faculty of Forestry and EnvironmentIPB UniversityBogor 16680Indonesia Department of Pharmacy Gunadarma UniversityDepok 16424Indonesia Research Collaboration Center of Biomass-Based Nano Cosmetic In collaboration with National Research and Innovation Agency(BRIN)SamarindaEast KalimantanIndonesia

Enhancing awareness of personal cleanliness and antibacterial resistance has intensified the antibacterial substance request on consumable products. Antibacterial agents that have been commercialized nowadays are produced from inorganic and non-renewable substances. This provides several drawbacks, particularly against health and environmental issues. Therefore, many scientists work on substituting fossil-fuel-based antibacterial agents with natural ones such as from biomass. Biomass derivatives, natural abundances of biopolymers in the world, amount to major compounds including polysaccharides (cellulose, hemicellulose, and chitosan) and polyphenol (tannin and lignin) substances which are capable to combat the growth of Gram-positive bacteria and Gram-negative bacteria. To date, no report focuses on a deep understanding of antibacterial properties derived from biomass and the internal and external factors effects. This work provides that gap because comprehensive knowledge is necessary before applying biomass to the products. The potency of biomass derivatives as antibacterial additives is also summarized. Basic knowledge of antibacterial characteristics to the application in products is highlighted in this review. Besides, the discussion about challenges and future perspectives is also delivered.

关键词： Antibacterial Application Biomass derivatives Challenge Future perspectives

Retrospective study evaluating association of colorectal tumors and hepatitis C virus

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World Journal of Virology 2024年第3期13卷 56-64页

作者： maya Gogtay Lekha Yadukumar Yuvaraj Singh mithil Gowda Suresh Aakriti Soni Anuroop Yekula Asha Bullappa George m Abraham Department of Hematology and Oncology Internal MedicineUniversity of Nebraska Medical CenterOmahaNE 68198United States Department of Internal medicine The Wright Center for Graduate Medical EducationScrantonPA 18505United States Department of Gastroenterology and Hepatology University of Massachusetts Chan Medical SchoolWorcesterMA 01605United States Department of Internal medicine Saint Vincent HospitalWorcesterMA 01608United States Department of Internal medicine St.Vincent HospitalWorcesterMA 01608United States Department of Community medicine SS Institute of Medical Sciences and Research CentreDavangere 577003KarnatakaIndia

BACKGROUND Chronic hepatitis C virus(HCV)has been associated with hepatic and extrahe-patic *** studies have shown an association between colorectal adenomas and HCV *** To study the prevalence of colorectal adenomas in patients with HCV compared to the general population and to evaluate if it is an independent risk factor for colorectal *** Patients were divided into HCV and non-HCV based on their HCV RNA *** with alcoholic liver disease,hepatitis B infection,and inflammatory bowel disease were *** variables were analyzed using the mann-Whitney U test,and categorical variables usingχ^(2) with Pmatched in both groups by propensity score matching,followed by multivariate regression *** Of the 415 patients screened,109 HCV patients and 97 non-HCV patients with colonoscopy results were included in the *** patients were older,had a smoking history,had less frequent aspirin use,and had a lower body mass index(BmI)(Pmber of patients with adenomas(adenoma detection rate of 53.2%vs 34%.P=0.006).We performed a propensity-matched multivariate analysis where HCV infection was significantly associated with colorectal adenoma(OR:2.070,P=0.019).CONCLUSION Our study shows a significantly higher rate of adenomas in HCV patients compared to the general *** studies would help determine if the increase in adenoma detection lowers the risk for colorectal cancer.

关键词： Hepatitis C Colon cancer Adenoma Polyps Colonoscopy

Genome-wide Studies Reveal Genetic Risk Factors for Hepatic Fat Content

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Genomics, Proteomics & Bioinformatics 2024年第2期22卷 57-68页

作者： Yanni Li Eline H.van den Berg Alexander Kurilshikov Dasha V.Zhernakova Ranko Gacesa Shixian Hu Esteban A.Lopera-maya Alexandra Zhernakova Lifelines Cohort Study Vincent E.de meijer Serena Sanna Robin P.F.Dullaart Hans Blokzijl Eleonora A.m.Festen Jingyuan Fu Rinse K.Weersma Department of Gastroenterology and Hepatology University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands Department of Genetics University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands Department of Gastroenterology and Hepatology Tianjin Medical University General HospitalTianjin Medical UniversityTianjin 300052China Laboratory of Genomic Diversity Center for Computer TechnologiesITMO UniversitySaint Petersburg 199034Russia Institute of Precision medicine the First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China Department of Surgery Section of Hepatobiliary Surgery and Liver TransplantationUniversity of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands Department of Endocrinology University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands Department of Pediatrics University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands 不详

Genetic susceptibility to metabolic associated fatty liver disease(mAFLD)is complex and poorly *** characterization of the genetic background of hepatic fat content would provide insights into disease etiology and causality of risk *** performed genome-wide association study(GWAS)on two noninvasive definitions of hepatic fat content:magnetic resonance imaging proton density fat fraction(mRI-PDFF)in 16,050 participants and fatty liver index(FLI)in 388,701 participants from the United Kingdom(UK)Biobank(UKBB).Heritability,genetic overlap,and similarity between hepatic fat content phenotypes were analyzed,and replicated in 10,398 participants from the University medical Center Groningen(UmCG)Genetics Lifelines Initiative(UGLI).meta-analysis of GWASs of mRI-PDFF in UKBB revealed five statistically significant loci,including two novel genomic loci harboring CREB3L1(rs72910057-T,P=5.40E−09)and GCm1(rs1491489378-T,P=3.16E−09),respectively,as well as three previously reported loci:PNPLA3,Tm6SF2,and *** of FLI in UKBB identified 196 genome-wide significant loci,of which 49 were replicated in UGLI,with top signals in ZPR1(P=3.35E−13)and FTO(P=2.11E−09).Statistically significant genetic correlation(rg)between mRI-PDFF(UKBB)and FLI(UGLI)GWAS results was found(rg=0.5276,P=1.45E−03).Novel mRI-PDFF genetic signals(CREB3L1 and GCm1)were replicated in the FLI *** identified two novel genes for mRI-PDFF and 49 replicable loci for *** a difference in hepatic fat content assessment between mRI-PDFF and FLI,a substantial similar genetic architecture was *** is identified as an easy and reliable approach to study hepatic fat content at the population level.

关键词： Hepatic fat content mAFLD Genome-wide association study Fatty liver index magnetic resonance imaging proton density fat fraction

Further Studies of the Cap Pushing Response in Honey Bees (Apis mellifera)

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Natural Science 2024年第5期16卷 45-64页

作者： Riley J. Wincheski Kiri Li N. Stauch Laura m. Grossner maya B. Zepeda James W. Grice Charles I. Abramson Department of Psychology Oklahoma State University Stillwater USA Laboratory of Comparative Psychology and Behavioral Biology Oklahoma State University Stillwater USA Department of Earth and Environmental Sciences California State University Fresno USA

The Cap Pushing Response (CPR) is a free-flying technique used to study learning and memory in honey bees (Apis mellifera). The series of experiments outlined in this paper aimed to test whether honey bees exhibit the cognitive concept of “expectancy” utilizing the CPR in a weight differentiation paradigm. Five previous experiments in our laboratory have explored whether the concept of expectancy can account for honey bee performance and have all failed to support the cognitive interpretation. The first experiment examined if bees could differentiate between the two caps in the amount of force they used to push the cap and the distance the cap was pushed when the caps were presented one at a time. The second experiment explored cap weight preference by presenting bees with a choice between the two caps. The third and fourth experiments tested the bee’s ability to expect reward or punishment based on cap weight. Results revealed that bees were found to have a strong preference for the light cap and therefore were not able to expect reward or punishment based on cap weight. These experiments contribute to the debate on whether bees have “cognitive” representations and continue to support the behaviorist interpretation.

关键词： Apis mellifera Cap Pushing Response Cognition Learning

Effect of music therapy on short-term psychological and physiological outcomes in mechanically ventilated patients: A randomized clinical pilot study

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Journal of Intensive medicine 2024年第04期04卷 515-525页

作者： Ettenberger m. Casanova-Libreros R. Chávez-Chávez J. Cordoba-Silva J.G. Betancourt-Zapata W. maya R. Fandiño-Vergara L.A. Valderrama m. Silva-Fajardo I. Hernández-Zambrano S.m. SONO - Centro de musicoterapia Bogotá Colombia Vice-Rectorate for Research Fundación Universitaria de Ciencias de la Salud Bogotá Colombia Department of Biomedical Engineering University of Los Andes Bogotá Colombia Department of Rehabilitation Sociedad de Cirugía de Bogotá Hospital de San José Bogotá Colombia Faculty of Nursing Fundación Universitaria de Ciencias de la Salud Bogotá Colombia

Background: Elevated anxiety levels are common in patients on mechanical ventilation (mV) and may challenge recovery. Research suggests music-based interventions may reduce anxiety during mV. However, studies investigating specific music therapy techniques, addressing psychological and physiological well-being in patients on mV, are scarce. methods: This three-arm randomized clinical pilot study was conducted with mV patients admitted to the intensive care unit (ICU) of Hospital San José in Bogotá, Colombia between march 7, 2022, and July 11, 2022. Patients were divided into three groups: intervention group 1 (IG1), music-assisted relaxation; intervention group 2 (IG2), patient-preferred therapeutic music listening; and control group (CG), standard care. The main outcome measure was the 6-item State-Anxiety Inventory. Secondary outcomes were: pain, measured with a visual analog scale; resilience, measured with the Brief Resilience Scale; agitation/sedation, measured with the Richmond Agitation–Sedation Scale; vital signs, including heart rate, blood pressure, oxygen saturation, and respiratory rate; days of mV; extubation success; and days in the ICU. Additionally, three patients underwent electroencephalography during the interventions. Results: Data from 23 patients were analyzed in this study. The age range of the patients was 24–84 years, with a median age of 66 years (interquartile range: 57–74). Of the 23 patients, 19 were female (82.6%). No statistically significant differences between the groups were observed for anxiety (P=0.330), pain (P=0.624), resilience (P=0.916), agitation/sedation (P=0.273), length of ICU stay (P=0.785), or vital signs. A statistically significant difference between the groups was found for days of mV (P=0.019). Electroencephalography measurements showed a trend toward delta and theta band power decrease for two patients and a power increase on both beta frequencies (slow and fast) in the frontal areas of the brain for one patient. Co

关键词： Anxiety Intensive care unit mechanical ventilation music therapy Pain

Evaluation of Human Impacts on Bartlett Pond Ecosystem, Laredo, Southern Texas, USA, through Empirical modeling

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Journal of Environmental Protection 2024年第4期15卷 497-526页

作者： maya P. Bhatt Amede Rubio Ganesh B. malla Cristobal Lopez Virginia morales Erick Vazquez Cano David marquez Orlando Berumen Alvarez Alfred Addo-mensah Department of Biology and Chemistry Texas A&M International University Laredo USA Department of mathematics Computer Geology and Physics University of Cincinnati-Clermont College Batavia USA

The trace elements chemistry of Bartlett Pond, a small shallow wetland pond in Laredo, Southern Texas, was sampled to evaluate the dynamics of trace elements impacts on water quality and ecosystems ecology of the pond. Two types of fish (bass and tilapia) were also sampled to see the trace element accumulation in different parts of their body. The concentrations of trace elements in water samples were found in the following order: Fe ≫Sb > Pb > As ≫Co > Tl > Cr > Cd within Bartlett Pond. Overall, the water quality of the pond is unacceptable for drinking and any other purposes as trace element concentrations (e.g. As, Cd, Co, Cr, Pb, Fe, Sb and Tl) are exceedingly higher (several fold) than the WHO and US EPA guidelines. Predictive and correlation analysis shows that most trace elements exhibit a strong positive correlation among them indicating the same anthropogenic sources and biogeochemical processes regulate these trace elements within the pond. Distributions of the trace elements in water exhibit different shapes mostly as positively skewed distribution for As, Cd, Co, Cr, and Tl, symmetrical distribution for Fe and almost symmetrical distribution for Pb and Sb. Concentrations of As, Co and Tl accumulated much higher in different parts of the Bass than Tilapia fish. The concentrations of As, Tl, Co, and Sb appeared significantly higher in different parts of the body of both Bass and Tilapia than the maximum SRm certified values. Accumulation of these contaminants in fish tissues pose increased health risks to humans who consume these contaminated fish although fishing is prohibited. Anthropogenic activities in the region primarily degrade the whole pond ecosystem ecology of the Bartlett Pond and waters of this pond to be not recommended for any use. These findings may be useful for the scientific community and concerned authorities to improve understanding about these precious natural resources and conservation of the ecosystem ecology.

关键词： Trace Elements Bartlett Pond Laredo Southern Texas Wetlands Ecosystem Ecology

Critical Technical Awakenings

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Journal of Social Computing 2021年第4期2卷 365-384页

作者： maya malik momin m.malik the School of Social Work McGill UniversityMontréalH3A 0G4Canada the Institute in Critical Quantitative Computational&Mixed MethodologiesJohns Hopkins UniversityBaltimoreMD 21218USA

Starting with Philip ***’s 1997 essay on“critical technical practice”,we consider examples of writings from computer science where authors describe“waking up”from a previously narrow technical approach to the world,enabling them to recognize how their previous efforts towards social change had been *** use these examples first to talk about the underlying assumptions of a technology-centric approach to social problems,and second to theorize these awakenings in terms of Paulo Freire’s idea of critical ***,understanding these awakenings among technical practitioners as examples of this more general phenomenon gives guidance for how we might encourage and guide critical awakenings in order to get more technologists working effectively towards positive social change.

关键词： critical technical practice critical consciousness perspective transformation education machine learning

Improving the prediction accuracy of soil nutrient classification by optimizing extreme learning machine parameters

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Information Processing in Agriculture 2020年第1期7卷 72-82页

作者： m.S.Suchithra maya L.Pai Department of Computer Science and IT Amrita School of Arts and SciencesKochiAmrita Vishwa Vidyapeetham682024India

The soil,Soul of Infinite Life,is the entity responsible for sustaining life on *** spite of significant advances in the service sector,agriculture remains the major provider of employment and source of revenue in *** testing is a valuable tool for evaluating the available nutrient status of soil and helps to determine the proper amount of nutrients to be added to a given soil based on its fertility and crop *** the current study,the soil test report values are used to classify several significant soil features like village wise soil fertility indices of Available Phosphorus(P),Available Potassium(K),Organic Carbon(OC)and Boron(B),as well as the parameter Soil Reaction(pH).The classification and prediction of the village wise soil parameters aids in reducing wasteful expenditure on fertilizer inputs,increase profitability,save the time of chemical soil analysis experts,improves soil health and environmental *** five classification problems are solved using the fast learning classification technique known as Extreme Learning machine(ELm)with different activation functions like gaussian radial basis,sine-squared,hyperbolic tangent,triangular basis,and hard *** the performance analysis of ELms with diverse activation functions for these soil parameter classifications,the gaussian radial basis function attains the maximum performance for four out of five problems,which goes above 80%in most of the accuracy rate calculations in every problem,followed by hyperbolic tangent,hard limit,triangular basis,and ***,the performance of the final classification problem,*** pH classification,gives moderate values with the gaussian radial basis and best performance(near 90%),with the hyperbolic tangent.

关键词： Extreme learning machine Activation functions Soil fertility indices Soil pH Classification Prediction

Petrogenesis of 3.15 Ga old Banasandra komatiites from the Dharwar craton, India： Implications for early mantle heterogeneity

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Geoscience Frontiers 2017年第3期8卷 467-481页

作者： J.m.maya Rajneesh Bhutani S.Balakrishnan S.Rajee Sandhya Department of Earth Sciences Pondicherry University

Spinifex-textured, magnesian （mgO 〉25 wt.%） komatiites from mesoarchean Banasandra greenstone belt of the Sargur Group in the Dharwar craton, India were analysed for major and trace elements and 147,146Sm-143,142Nd systematics to constrain age, petrogenesis and to understand the evolution of Archean mantle. major and trace element ratios such as CaOJAl203, Al2O3JTiO2, GdJYb, LaJNb and NbJY suggest aluminium undepleted to enriched compositional range for these komatiites. The depth of melting is estimated to be varying from 120 to 240 km and trace-element modelling indicates that the mantle source would have undergone multiple episodes of melting prior to the generation of magmas parental to these komatiites. Ten samples of these komatiites together with the published results of four samples from the same belt yield 147Sm-143Nd isochron age of ca. 3.14 Ga with an initial ENd（t） value of ＋3.5. High precision measurements of 142Nd/144Nd ratios were carried out for six komatiite samples along with standards AmES and La Jolla. All results are within uncertainties of the terrestrial samples. The absence of 142Nd/144Nd anomaly indicates that the source of these komatiites formed after the extinction of 146Sm, i.e. 4.3 Ga ago. In order to evolve to the high eNd（t） value of ＋3.5 by 3.14 Ga the time-integrated ratio of 147Sm/144Nd should be 0.2178 at the minimum. This is higher than the ratios estimated, so far, for mantle during that time. These results indicate at least two events of mantle differentiation starting with the chondritic composition of the mantle. The first event occurred very early at ~ 4.53 Ga to create a global early depleted reservoir with superchondritic Sm/Nd ratio, The source of Isua greenstone rocks with positive ~42Nd anomaly was depleted during a second differentiation within the life time of 146Sm, i.e. prior to 4.46 Ga. The source mantle of the Banasandra komatiite was a result of a differentiation event that occurred after the extinction of the 14

关键词： Komatiite Dharwar craton Early mantle differentiation 142Nd/144Nd Sm-Nd geochronology