检索结果-南通市图书馆

Non-anatomical liver resection for hepatocellular carcinoma:the SegSubTe classification to overcome the problem of heterogeneity

引用

Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 265-271页

作者： Mattia Garancini Alessandro Fogliati mauro Alessandro scotti Cristina Ciulli Francesca Carissimi Antonio Rovere Luca Gianotti Fabrizio Romano Unit of Hepatobiliopancreatic Surgery Department of SurgeryASST-MonzaSan Gerardo HospitalUniversity of Milano-Bicoccavia Pergolesi 33MonzaMB 20052Italy Interventional Radiology Department of RadiologyASST-MonzaSan Gerardo HospitalMilano-Bicocca Universityvia Pergolesi 33MonzaMB 20052Italy

Background:The superiority of anatomical resection(AR)***-anatomical resection(NAR)in the surgical management of hepatocellular carcinoma(HCC)is *** are well-defined procedures,whereas the lack of NAR standardization results in heterogeneous *** study aimed to introduce the SegSubTe classification for NAR detailing the appropriateness of the level of surgical section of the Glissonean pedicles feeding the ***:A single-center retrospective analysis of pre-and postoperative imaging of consecutive patients treated with NAR for single HCC between 2012 and 2020 was *** quality of surgery was assessed classifying the type of vascular supply and the level of surgical section(segmental,subsegmental or terminal next to the tumor)of vascular pedicles feeding the HCCs;then,the population was divided in“SegSubTe-IN”or“SegSubTe-OUT”groups,and the tumor recurrence and survival were ***:Ninety-seven patients who underwent NAR were included;76%were SegSubTe-IN and 24%were *** disease recurrence,local recurrence and cut-edge recurrence in the SegSubTe-IN ***-OUT groups were 50%vs.83%(P=0.006),20%vs.52%(P=0.003)and 16%vs.39%(P=0.020),***-OUT odds ratio for local recurrence was 4.1 at univariate regression ***-,three-,and five-year disease-free survival rates in the SegSubTe-IN ***-OUT groups were 81%,58%and 35%vs.46%,21%and 11%,respectively(P<0.001).Conclusions:The SegSubTe classification is a useful tool to stratify and standardize NAR for HCC,aiming at improving long-term oncological outcomes and reducing the heterogeneity of quality of NAR for HCC.

关键词： Hepatocellular carcinoma Intraoperative ultrasound Liver surgery Computed tomography Surgical procedure

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rethinking the Barcelona clinic liver cancer guidelines:Intermediate stage and Child-Pugh B patients are suitable for surgery?

引用

World Journal of Gastroenterology 2021年第21期27卷 2784-2794页

作者： Fabrizio Romano Marco Chiarelli Mattia Garancini mauro scotti mauro Zago Gerardo Cioffi Matilde De Simone Ugo Cioffi Department of Surgery School of Medicine and SurgeryUniversity of Milano-BicoccaMonza 20900Italy Emergency and Robotic Surgery A.Manzoni HospitalASST LeccoLecco 23900Italy Department of General Surgery San Gerardo HospitalMonza 20900Italy Department of Sciences and Technologies Universitàdegli Studi del Sannio di BeneventoBenevento 82100Italy Department of Surgery University of MilanMilano 20122Italy

According to Barcelona Clinic Liver Cancer recommendations,intermediate stage hepatocellular carcinomas(stage B)are excluded from liver resection and are referred to palliative ***,Child-Pugh B patients are not usually candidates for liver ***,many hepatobiliary centers in the world manage patients with intermediate stage hepatocellular carcinoma or Child-Pugh B cirrhosis with liver resection,maintaining that hepatic resection is not contraindicated in selected patients with non–early-stage hepatocellular carcinoma and without normal liver *** studies demonstrate that resection provides the best survival benefit for selected patients in very early/early and even in intermediate stages of Barcelona Clinic Liver Cancer classification,and this treatment gives good results in the setting of multinodular,large tumors in patients with portal hypertension and/or Child-Pugh B *** this review we explore this controversial topic,and we show through the literature analysis how liver resection may improve the short-and long-term survival rate of carefully selected Barcelona Clinic Liver Cancer B and Child-Pugh B hepatocellular carcinoma ***,other large clinical studies are needed to clarify which patients with intermediate stage hepatocellular carcinoma are most likely to benefit from liver resection.

关键词： Liver surgery Hepatocellular carcinoma Barcelona liver clinic cancer Child B Intermediate stage

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Branching patterns of the left portal vein and consequent implications in liver surgery:The left anterior sector

引用

Hepatobiliary & Pancreatic Diseases International 2022年第4期21卷 399-402页

作者： Mattia Garancini mauro Alessandro scotti Luca Gianotti Antonio Rovere Fabio Uggeri Marco Braga Fabrizio Romano Unit of Hepatobiliary Pancreatic Surgery Department of General Surgery 1ASST-MonzaSan Gerardo HospitalMilano-Bicocca Universityvia Pergolesi 3320900 MonzaMBItaly Unit of Interventional Radiology Department of RadiologyASST-MonzaSan Gerardo HospitalMilano-Bicocca Universityvia Pergolesi 3320900 MonzaMBItaly

To the Editor: There are still some open issues about the systematization of the knowledge of the branching of the left portal vein(LPV) and the division in anatomo-functional units within the left liver. The first controversial topic concerns the division of S4 in subsegments. The Brisbane 20 0 0 system of Nomenclature of Hepatic Anatomy and Resections(B20 0 0) [1] does not mention such subdivision, but in literature this is still a matter of discussion.

关键词： branching portal discussion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Is there a role for treatment-oriented surgery in liver metastases from gastric cancer?

引用

World Journal of Clinical Oncology 2020年第7期11卷 477-494页

作者： Fabio Uggeri Lorenzo Ripamonti Enrico Pinotti mauro Alessandro scotti Simone Famularo Mattia Garancini Luca Gianotti Marco Braga Fabrizio Romano School of Medicine and Surgery University of Milano-BicoccaDepartment of SurgerySan Gerardo HospitalMonza 20900Italy Department of Surgery San Gerardo HospitalMonza 20900Italy

BACKGROUND Distant metastases are found in approximately 35%of patients with gastric cancer at their first clinical observation,and of these,4%-14%involves the ***,only 0.4%-2.3%of patients with metastatic gastric cancer are eligible for radical *** surgical resection for gastric cancer metastases is still debated,there have been changes in recent years,although several clinical issues remain to be defined and that must be taken into account before surgery is *** To analyze the clinicopathological factors related to primary gastric tumor and metastases that impact the survival of patients with liver metastatic gastric *** We performed a systematic review of the literature from 2000 to 2018 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses *** study protocol was based on identifying studies with clearly defined purpose,eligibility criteria,methodological analysis,and patient *** We selected 47 studies pertaining to the purpose of the review,which involved a total of 2304 *** survival was 7-52.3 mo,median disease-free survival was 4.7-18 *** 1-,2-,3-,and 5-year overall survival(OS)was 33%-90.1%,10%-60%,6%-70.4%,and 0%-40.1%,*** five papers reported the 10-year OS,which was 5.5%–31.5%.The general recurrence rate was between 55.5%and 96%,and that for hepatic recurrence was between 15%and 94%.CONCLUSION Serous infiltration and lymph node involvement of the primary cancer indicate an unfavorable prognosis,while the presence of single metastasis or≤3 metastases associated with a size of<5 cm may be considered data that do not contraindicate liver resection.

关键词： Hepatic metastases Gastric cancer Prognostic factor Survival Hepatectomy Surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CYP72A67 Catalyzes a Key Oxidative Step in Medicago truncatula Hemolytic Saponin Biosynthesis

引用

Molecular Plant 2015年第10期8卷 1493-1506页

作者： Elisa Biazzi Maria Carelli Aldo Tava Pamela Abbruscato Ilaria Losini Pinarosa Avato Carla scotti Ornella Calderini Consiglio per la ricerca in agricoltura e I'analisi dell'economia agraria (CRA) Centro di Ricerche per le Produzioni Foraggere e Lattiero Casearie 26900 Lodi Italy Parco Tecnologico Padano 26900 Lodi Italy Dipartimento di Farmacia-Scienze del Farmaco Universita degli Studi di Bad Aldo Moro 70125 Bari Italy Consiglio Nazionale delle Ricerche (CNR) Istituto di Bioscienze e Biorisorse 06128 Perugia Italy These authors contributed equally to this article.

In the Medicago genus, triterpenic saponins are bioactive secondary metabolites constitutively synthesized in the aerial and subterranean parts of plants via the isoprenoid pathway. Exploitation of saponins as pharmaceutics, agrochemicals and in the food and cosmetic industries has raised interest in identifying the enzymes involved in their synthesis. We have identified a cytochrome P450 （CYP72A67） involved in hemolytic sapogenin biosynthesis by a reverse genetic TILLING approach in a Medicago truncatula ethyl- methanesulfonate （EMS） mutagenized collection. Genetic and biochemical analyses, mutant complementation, and expression of the gene in a microsome yeast system showed that CYP72A67 is responsible for hydroxylation at the C-2 position downstream of oleanolic acid synthesis. The affinity of CYP72A67 for substrates with different substitutions at multiple carbon positions was investigated in the same in vitro yeast system, and in relation to two other CYP450s （CYP72A68） responsible for the production of medicagenic acid, the main sapogenin in M. truncatula leaves and roots. Full sib mutant and wild-type plants were compared for their sapogenin profile, expression patterns of the genes involved in sapogenin synthesis, and response to inoculation with Sinorhizobium meliloti. The results obtained allowed us to revise the hemolytic sapogenin pathway in M. truncatula and contribute to highlighting the tissue specificities （leaves/roots） of sapogenin synthesis.

关键词： Medicago truncatula saponin pathway cytochrome P450 CYP72A67 CYP72A68 TILLING analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pollen viability of Polygala paniculata L.(Polygalaceae)using different staining methods

引用

BIOCELL 2012年第3期36卷 143-145页

作者： VIVIANE DAL-SOUTO FRESCURA HAYWOOD DAIL LAUGHINGHOUSE IV THAIS scotti DO CANTO-DOROW SOLANGE BOSIO TEDESCO Laboratory of Cytogenetics and Genotoxicity Department of BiologyCentro de Ciências Naturais e Exatas(CCNE)Universidade Federal de Santa Maria(UFSM)Avenida Roraimanº1000Cep.97105-900CamobiSanta MariaRio Grande do SulBrasil Centre for Protein Engineering Institute of Chemistry B6University of LiègeBelgium

Polygala paniculata *** a medicinal plant that grows in the Brazilian Atlantic coast,known as‘barba-de-São-João’,‘barba-de-bode’,‘vassourinha branca’,and‘mimosa’.In this study,pollen viability was estimated by three different staining methods:2%acetic orcein,2%acetic carmine,and Alexander’s *** young inflorescences of twenty accessions were collected and fixed in a solution of ethanol:acetic acid(3:1)for 24 hours,then stored in ethanol 70%under *** slides per plant,two for each stain,were prepared by squashing,and 300 pollen grains per slide were *** viability was high(>70%)for most accessions of *** using the Alexander’s stain,which proved the most adequate method to estimate pollen viability.

关键词： pollen grains barba-de-bode acetic orcein acetic carmine Alexander’s stain

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

GTAW焊接过程中熔池发展的数值模拟及与实验结果的比较

引用

四川大学学报（工程科学版） 2002年第6期34卷 47-51页

作者：杨雪峰 Aristeuda Silveira Neto Américo scotti 四川大学化学工程学院四川成都610065 Universidade Federal de Uberlandia

用描述等离子弧和熔池中的流体流动和传热过程的数学模型对熔池的发展进行了数值模拟。模拟结果和文献中实验结果的比较表明 ,该数学模型能较好地预测熔池的形状和大小。

关键词：焊接过程数值模拟熔池发展 GTAW焊接等离子弧数学模型传热过程

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Some insight on the structure/activity relationship of metal nanoparticles in Cu/SiO2 catalysts

引用

Chinese Journal of Catalysis 2019年第11期40卷 1788-1794页

作者： Nicola scotti Elisabetta Finocchio Claudio Evangelisti Marcello Marelli Rinaldo Psaro Nicoletta Ravasio Federica Zaccheria The Institute of Molecular Science and Technologies (ISTM) CNR Research Centres LabCat via C. Golgi 19 20133 Milano Italy Dip. Ingegneria Civile Chimica e Ambientale (DICCA) Scuola Politecnica Università di Genova Via all'Opera Pia 15 16145 Genova Italy

The activity of two Cu/SiO2 catalysts prepared by the chemisorption hydrolysis technique has been tested in the hydrogenation reaction of 3-methyl-cyclohexanone. Both catalysts were found to be very active at 60 ℃ and 1 atm of H2. Characterization of the materials by FT-IR of adsorbed CO and TEM put in light the presence of well formed Cu cristallites. By assuming a cuboctahedral model we could show that the hydrogenation activity is linked to high coordination sites on the metal particle. A comparison is also reported with a sample prepared by ammonia evaporation that was found to be inactive in the hydrogenation reaction under the same experimental conditions.

关键词： Cu catalysts Metal particle morphology Lewis acid sites Hydrogenation Bifunctional catalysts

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Analgesic-like activity of perillyl acetate:In vivo and in silico studies

引用

Asian Pacific Journal of Tropical Biomedicine 2022年第4期12卷 156-163页

作者： Renan Braga Humberto Andrade Ryldene Cruz Mayara Maia Carolina Lima Anderson Santos AndréMiranda Allana Duarte Marcus scotti Reinaldo Almeida Damião Sousa Postgraduate Program in Natural and Synthetic Bioactive Products Federal University of Paraíba58051-970João PessoaPBBrazil Research Institute for Drugs and Medicines Federal University of ParaíbaCP 5009João Pessoa58051-900PBBrazil Department of Pharmaceutical Sciences Federal University of Paraíba58051-970João PessoaPBBrazil

Objective:To evaluate the antinociceptive activity of perillyl acetate in mice and in silico ***:The vehicle,perillyl acetate(100,150 and/or 200 mg/kg,i.p.),diazepam(2 mg/kg,i.p.)or morphine(6 mg/kg,i.p.)was administered to mice,*** test,acetic acidinduced abdominal writhing,formalin-induced nociception,hot plate test,and tail-flick test were *** receptorsinvolvement in perillyl acetate antinociceptive effect was also ***:Perillyl acetate did not affect the motor coordination of ***,it reduced the number of acetic acid-induced abdominal twitches and licking times in the formalin *** was an increase of latency time in the tail-flick test of 30 and *** with naloxone reversed the antinociceptive effect of perillyl acetate(200 mg/kg).In silico analysis demonstrated that perillyl acetate could bind toμ-opioid ***:Perillyl acetate has antinociceptive effect at the spinal level in animal nociception models,without affecting the locomotor integrity and possibly throughμ-opioid *** silico studies have suggested that perillyl acetate can act as aμ-opioid receptor agonist.

关键词： Analgesic Biological products Opioid Essential oil Pain Monoterpene Perillyl acetate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Aboveground nutrient components of Eucalyptus camaldulensis and E. grandis in semiarid Brazil under the nature and the mycorrhizal inoculation conditions

引用

Journal of Forestry Research 2009年第1期20卷 15-22页

作者： Marcela C. Pagano Antonio F. Bellote Maria R. scotti Microorganism-Plant Interaction LaboratolT Institute of Biological Sciences Federal University of Minas Gerais Av. Antonio Carlos 6627 Pampulha CEP： 31270-901 Belo Horizonte MG Brazil Embrapa Forestry Estrada da Ribeira km 111 Caixa Postal 319 - Colombo PR - 83411-000- Brazil.

A study was conducted to evaluate the aboveground biomass, nutrient content and the percentages of mycorrhizal colonization in Eucalyptus camaldulensis and Eucalyptus grand＆ plantations in the semiarid region （ 15° 09′ S 43° 49′ W） in the north of the State of Minas Gerais in Brazil. Results show that the total above-ground biomass （dry matter） was 33.6 ***^-1 for E. camaldulensis and 53.1 Mg·ha^-1 for E. grandis. The biomass of the stem wood, leaves, branches, and stein bark for E. camaldulens accounted for 64.4%, 19.6%, 15.4%, and 0.6% of the total biomass, respectively （Table 2）; meanwhile a similar partition of the total above-ground biomass was also found for E. grand＆. The dry matter of leaves and branches of E. camaldulensis accounted for 35% of total biomass, and the contents of N, P, K, Ca, Mg, and S in leaves and branches accounted for 15.5%, 0.7%, 12.3%, 22.6%, 1.9%, and 1.4% of those in total above-ground biomass, respectively. In the trunk （bark and wood）, nutrient accumulation in general was lower. Nutrient content of E. grand＆ presented little variation compared with that orE. camaJd^llensis. Wood localized in superior parts of trunk presented a higher concentration of P and bark contained significant amounts of nutrients, especially in E. grand＆. This indicated that leaving vegetal waste is of importance on the site in reducing the loss of tree productivity in this semi-arid region. The two species showed mycotrophy.

关键词： Eucalyptus biomass nutrient components semi-arid region mycorrhizal symbioses Brazil

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：