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Petroleum Research 2022年第1期7卷 1-12页

作者： Hongbing Xie mauricio Fiallos torres Penyu Cheng Wei Yu Yuzhong Xin Jijun Miao Muwei Cheng Beijing Karst S&T Limited Beijing100083China Sim Tech LLC KatyTX77494USA RIPED Beijing100083China University of Texas at Austin AustinTX78712USA

Characterizing natural fractures has a decisive effect on production forecasts in fractured oil and gas *** Fracture Networks(DFN)constitutes the main modeling framework for fractured ***,myriads of uncertainties are enclosed prior modeling representative stochastic or deterministic DFN *** paper presents a novel methodology for DFN calibration and an efficacious field application,which incorporatesWell-testing interpretation,Embedded Discrete Fracture Model(EDFM)framework,and numerical reservoir *** proposed workflow starts with the DFN generation from seismic data,imaging logging data and core *** multiple DFNs are modeled,well-test analysis is employed to calibrate the intrinsic properties of fractures at different ***,these fracture networks are characterized dynamically by EDFM,which promotes capturing the optimal fracture model quickly ***,pressure and production history match are reached for the DFN realization that honors the optimal fracture model.

关键词： DFN EDFM DFN screening Fracture networks Natural fractures

Adequation of a Virtual Immersive Environment for a Learning-Teaching Interaction Using the Limem 3d Method

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通讯和计算机（中英文版） 2015年第2期12卷 57-66页

作者： Diego mauricio torres Arias Helmuth Trefftz Department of software engineer Universidad EAFIT Department of Computer and Systems Laboratory of Virtual Reality Universidad EAFIT Medellin Colombia

Optimal Risk-Sensitive Filtering for System Stochastic of Second and Third Degree

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Intelligent Control and Automation 2011年第1期2卷 47-56页

作者： Ma Aracelia Alcorta-Garcia Sonia Gpe Anguiano Rostro mauricio torres torres 不详

The risk-sensitive filtering design problem with respect to the exponential mean-square cost criterion is con-sidered for stochastic Gaussian systems with polynomial of second and third degree drift terms and intensity parameters multiplying diffusion terms in the state and observations equations. The closed-form optimal fil-tering equations are obtained using quadratic value functions as solutions to the corresponding Focker- Plank-Kolmogorov equation. The performance of the obtained risk-sensitive filtering equations for stochastic polynomial systems of second and third degree is verified in a numerical example against the optimal po-lynomial filtering equations (and extended Kalman-Bucy for system polynomial of second degree), through comparing the exponential mean-square cost criterion values. The simulation results reveal strong advan-tages in favor of the designed risk-sensitive equations for some values of the intensity parameters.

关键词： Optimal Nonlinear Filtering Risk-Sensitive Filtering Extended Kalman-Bucy Filtering

The novel role of endoplasmic reticulum–associated degradation in brown adipocytes

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The novel role of endoplasmic reticulum–associated degradat...

Chronic total occlusion:To treat or not to treat

第四届中国生物物理学会代谢生物学分会学术研讨会

作者： Zhangsen Zhou mauricio torres Ling Qi Shanghai Institute of Nutrition and Health CAS

＜正＞Organelles within a cell communicate with each other to exchange information and maintain cellular homeostasis. Indeed, various diseases such as neurodegeneration and type-2 diabetes are linked to dysregulation of organelle communication. However, the underlying molecular mechanism remains largely unclear. Sel1L-Hrd1 endoplasmic reticulum （ER）-associated degradation （ERAD）is a principal quality control mechanism which clears misfolded proteins in the ER for proteasomal degradation in the cytosol. Here we showed that Sel1L-Hrd1ERAD controls ER-mitochondria contacts and mitochondrial dynamics in brown adipocytes. Using transmission and 3D scanning electron microscopy,

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World Journal of Cardiology 2014年第7期6卷 621-629页

作者： Alfredo Bardají Judit Rodriguez-López mauricio torres-Sánchez Servicio de Cardiología Hospital Universitario de Tarragona Joan XXⅢUniversitat Rovira Virgili3007 TarragonaEspa■a

Over the last two decades,there has been increasing interest in new techniques for the percutaneous treatment of coronary chronic total occlusions(CTO),which have a success rate that is much higher than that of a few years *** rise in percutaneous treatment for these lesions is due to its ability to improve the symptoms and prognosis of patients in the chronic and stable phase of coronary *** data suggest that successful percutaneous coronary intervention for CTO is associated with improvement in patient symptoms,quality of life,left ventricular function,and survival,compared with those with unsuccessful CTO ***,all the scientific evidence supporting this treatment comes from observational studies,and no randomized study comparing percutaneous treatment with medical treatment has yet been published.A major limitation of these studies is their observational design,with limited information with regard to potential baseline differences between the successful vs unsuccessful *** randomized studies,patients should be selected very carefully,especially if they are asymptomatic or very few symptoms,and the benefits obtained in terms of complications during the procedure,the quality of life obtained and further ischemic events avoided should be evaluated *** this review,we will consider the available information supporting percutaneous treatment for chronic occlusions,as well as the areas of uncertainty where more research projects are required.

关键词： Chronic total occlusion Percutaneous coronary intervention

A new-generation Embedded Discrete Fracture Model calibration workflow applied to the characterization of complex naturally fracture reservoir

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Petroleum Research 2022年第01期 1-12页

作者： Hongbing Xie mauricio Fiallos torres Penyu Cheng Wei Yu Yuzhong Xin Jijun Miao Muwei Cheng Beijing Karst S&T Limited Sim Tech LLC RIPED University of Texas at Austin

Characterizing natural fractures has a decisive effect on production forecasts in fractured oil and gas reservoirs. Discrete Fracture Networks(DFN) constitutes the main modeling framework for fractured geosystems. However, myriads of uncertainties are enclosed prior modeling representative stochastic or deterministic DFN ensembles. This paper presents a novel methodology for DFN calibration and an efficacious field application, which incorporates Well-testing interpretation, Embedded Discrete Fracture Model(EDFM) framework, and numerical reservoir simulation. The proposed workflow starts with the DFN generation from seismic data, imaging logging data and core data. After multiple DFNs are modeled,well-test analysis is employed to calibrate the intrinsic properties of fractures at different locations. Then,these fracture networks are characterized dynamically by EDFM, which promotes capturing the optimal fracture model quickly screened. Finally, pressure and production history match are reached for the DFN realization that honors the optimal fracture model.

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Preprocessing of 2-Dimensional Gel Electrophoresis Images Applied to Proteomic Analysis： A Review

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Genomics, Proteomics & Bioinformatics 2018年第1期16卷 63-72页

作者： Manuel mauricio Goez Maria Constanza torres-Madronero Sarah Rothlisberger Edilson Delgado-Trejos Automatics Electronics and Computer Science Research Group Faculty of Engineering Instituto Tecnologico Metropolitano Medellin 050012 Colombia Biomedical Innovation and Research Group Faculty of Applied and Exact Sciences lnstituto Tecnologico Metropolitano Medellin 050012 Colombia Quality Metrology and Production Research Group Faculty of Economic and Management Sciences Instituto Tecnologico Metropolitano Medellin 050012 Colombia

Various methods and specialized software programs are available for processing two- dimensional gel electrophoresis （2-DGE） images. However, due to the anomalies present in these images, a reliable, automated, and highly reproducible system for 2-DGE image analysis has still not been achieved. The most common anomalies found in 2-DGE images include vertical and hor- izontal streaking, fuzzy spots, and background noise, which greatly complicate computational anal- ysis. In this paper, we review the preprocessing techniques applied to 2-DGE images for noise reduction, intensity normalization, and background correction. We also present a quantitative comparison of non-linear filtering techniques applied to synthetic gel images, through analyzing the performance of the filters under specific conditions. Synthetic proteins were modeled into a two-dimensional Gaussian distribution with adjustable parameters for changing the size, intensity, and degradation. Three types of noise were added to the images： Gaussian, Rayleigh, and exponen- tial, with signal-to-noise ratios （SNRs） ranging 8-20 decibels （dB）. We compared the performanceof wavelet, contourlet, total variation （TV）, and wavelet-total variation （WTTV） techniques using parameters SNR and spot efficiency. In terms of spot efficiency, contourlet and TV were more sen- sitive to noise than wavelet and WTTV. Wavelet worked the best for images with SNR ranging 10- 20 dB, whereas WTTV performed better with high noise levels. Wavelet also presented the best per- formance with any level of Gaussian noise and low levels （20-14 dB） of Rayleigh and exponential noise in terms of SNR. Finally, the performance of the non-linear filtering techniques was evaluated using a real 2-DGE image with previously identified proteins marked. Wavelet achieved the best detection rate for the real image.

关键词： Background correction Filtering Noise reduction Preprocessing 2D gel electrophoresis

DNA metabarcoding reveals seasonal changes in diet composition across four arthropod-eating lizard species(Phrynosomatidae:Sceloporus)

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Integrative Zoology 2024年第3期19卷 480-495页

作者： mauricio HERNÁNDEZ Stephanie HEREIRA-PACHECO Antton ALBERDI Aníbal H.DÍAZ DE LA VEGA-PÉREZ Arturo ESTRADA-torres Sergio ANCONA Yendi E.NAVARRO-NOYA Doctorado en Ciencias Biológicas Centro Tlaxcala de Biología de la ConductaUniversidad Autónoma de TlaxcalaTlaxcalaMexico Estación Científica La Malinche Centro Tlaxcala de Biología de la ConductaUniversidad Autónoma de TlaxcalaTlaxcalaMexico Center for Evolutionary Hologenomics The Globe InstituteUniversity of CopenhagenCopenhagenDenmark Consejo Nacional de Ciencia y Tecnología-Centro Tlaxcala de Biología de la Conducta Universidad Autónoma de TlaxcalaTlaxcalaMexico Departamento de Ecología Evolutiva Instituto de EcologíaUniversidad Nacional Autónoma de MéxicoMexico CityMexico Laboratorio de Interacciones Bióticas Centro de Investigación en Ciencias BiológicasUniversidad Autónoma de TlaxcalaSan Felipe IxtacuixtlaTlaxcalaMexico

Diet composition and its ecological drivers are rarely investigated in coexisting closely related *** used a molecular approach to characterize the seasonal variation in diet composition in four spiny lizard species inhabiting a mountainous *** metabarcoding revealed that the lizards Sceloporus aeneus,***,***,and *** mostly consumed arthropods of the orders Hemiptera,Araneae,Hymenoptera,and *** terrestrial lizards *** and *** mostly predated ants and spiders,whereas the arboreal–saxicolous *** and saxicolous *** largely consumed grasshoppers and *** taxonomic and phylogenetic diversity of the prey was higher during the dry season than the rainy season,likely because reduced prey availability in the dry season forced lizards to diversify their diets to meet their nutritional *** and phylogenetic composition varied seasonally depending on the species,but only dietary composition varied with *** dietary turnover was greater in *** than in ***,suggesting site-specific seasonal variability in prey availability;no other differences among species were ***,which lives at the highest altitude in our study site,displayed interseasonal variation in diet *** differences were correlated with the species’feeding strategies and elevational distribution,which likely contributed to the coexistence of these lizard species in the studied geographic area and beyond.

关键词： arthropod-eating lizards diet breadth environmental barcoding mountainous ecosystem seasonal dietary shifts

Sustainable Methods and Techniques in Old and New Public Constructions

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Journal of Civil Engineering and Architecture 2013年第11期7卷 1433-1444页

作者： mauricio Noya Ana Lucia torres Seroa da Motta Wagner Abreu Department of Civil Engineering Universidade Federal Fluminense (UFF) Niteroi 24210-240 Brazil Brazilian Institute of Geography and Statistics Rio de Janeiro 20021-120 Brazil

This article is about the methods and techniques used in the building ＂retrofit＂ in modernist style designed by the architect Affonso Eduardo Reidy in the fifties, and also about the project of the new Rio de Janeiro MIS （Museum of Image and Sound）, under construction, by The North-American office Diller Scofidio ＋ Renfro, both located in the city of Rio de Janeiro. These constructions present a wide view of the concept of sustainability, not commonly used in public buildings in Brazil. In the building designed by Reidy, which belongs to the State of Rio de Janeiro, the regeneration to host the new headquarters of the State Department of Taxation and Finance respected its original characteristics and used smart and sustainable design techniques, as well as recyclable materials. On the other hand, the project of the new museum at Copacabana Beach was entirely planned on sustainable bases and it includes the application of building techniques concerning that purpose. This article presents a study of these two cases and evaluates the techniques and materials used in one another. Observing the principles of sustainability in construction is a pioneering initiative of the State Government. This article aims at making the scientific community aware of the needs of immediate adoption of sustainability techniques in Civil Engineering, not only in the construction of new buildings, but also in the regeneration of the existing ones, as well as the need of imperious adoption of sustainable techniques when it comes to maintainability.

关键词： Sustainability building techniques retrofit public buildings.

A multi-platform analysis of human gingival crevicular fluid reveals ferroptosis as a relevant regulated cell death mechanism during the clinical progression of periodontitis

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International Journal of Oral Science 2024年第2期16卷 265-279页

作者： Alfredo torres M.Angélica Michea Ákos Végvári Marion Arce Valentina Pérez Marcela Alcota Alicia Morales Rolando Vernal mauricio Budini Roman A.Zubarev Fermín E.González Laboratory of Experimental Immunology&Cancer Faculty of DentistryUniversity of ChileSantiagoChile Department of Conservative Dentistry Faculty of DentistryUniversity of ChileSantiagoChile Division of Chemistry I Department of Medical Biochemistry and BiophysicsKarolinska InstitutetStockholmSweden Periodontal Biology Laboratory Faculty of DentistryUniversidad de ChileSantiagoChile Laboratory of Cellular and Molecular Pathology Institute for Research in Dental SciencesFaculty of DentistryUniversity of ChileSantiagoChile

Ferroptosis is implicated in the pathogenesis of numerous chronic-inflammatory diseases,yet its association with progressive periodontitis remains *** investigate the involvement and significance of ferroptosis in periodontitis progression,we assessed sixteen periodontitis-diagnosed *** progression was clinically monitored over twelve weeks via weekly clinical evaluations and gingival crevicular fluid(GCF)collection was performed for further *** metrics,proteomic data,in silico methods,and bioinformatics tools were combined to identify protein profiles linked to periodontitis progression and to explore their potential connection with *** western blot analyses validated key ***,a single-cell RNA sequencing(scRNA-seq)dataset(GSE164241)for gingival tissues was analyzed to elucidate cellular dynamics during periodontitis *** progression was identified as occurring at a faster rate than traditionally *** samples from progressing and non-progressing periodontal sites showed quantitative and qualitatively distinct proteomic *** addition,specific biological processes and molecular functions during progressive periodontitis were revealed and a set of hub proteins,including SNCA,CA1,HBB,SLC4A1,and ANK1 was strongly associated with the clinical progression status of ***,we found specific proteins-drivers or suppressors-associated with ferroptosis(SNCA,FTH1,HSPB1,CD44,and GCLC),revealing the co-occurrence of this specific type of regulated cell death during the clinical progression of ***,the integration of quantitative proteomic data with scRNA-seq analysis suggested the susceptibility of fibroblasts to *** analyses reveal proteins and processes linked to ferroptosis for the first time in periodontal patients,which offer new insights into the molecular mechanisms of progressive periodontal *** findings may le

关键词： finding progression faster