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Reliability of Relative Paleointensity Recorded in Chinese Loess-Paleosol Sediments

Acta Geologica Sinica(English Edition) 2012年第5期86卷 1276-1288页

作者： YANG Tianshui LI Haiyan WU Huaichun YANG Zhenyu ZHANG Shihong HYODO masayuki State Key Laboratory of Biogeology and Environmental Geology China University of GeosciencesBeijing 100083China School of the Earth Sciences and Resources China University of GeosciencesBeijing 100083China School of Ocean Sciences and Resources China University of GeosciencesBeijing 100083China Institute of Geomechanics Chinese Academy of Geological SciencesBeijing 100081China Research Center for Inland Seas Kobe UniversityKobe 657-8501Japan

A detailed paleomagnetic and rock-magnetic investigation spanning loess L7 to paleosol S8 has been carried out at the Baoji and Xifeng sections. Results of anisotropy of magnetic susceptibility confirm that the studied loess-paleosol sediments retain primary sedimentary fabrics. Stepwise thermal demagnetization shows that two well-defined magnetization components can be isolated from both loess and paleosol specimens. A low-temperature component, isolated between 100°C and 200°C, is consistent with the present geomagnetic field direction, and a high-temperature component, isolated between 200-300°C and 620-680°C, includes clearly normal and reversed polarities. Isothermal remanent magnetization and thermomagnetic analyses indicate that characteristic remanent magnetization is mainly carried by magnetite and hematite. The Day plot, together with the stratigraphic variations of rock-magnetic parameters, shows that the uniformity of magnetic mineralogy and grain size fulfills the criteria for relative paleointensity （RPI） studies. RPI records have been constructed using natural remanent magnetization （NRM） intensity after thermal demagnetization at 300°C normalized by low-frequency magnetic susceptibility （NRM 300 /χ）. The results show that the RPI record from the Baoji section, where pedogenesis is quite weak, is compatible with the stacked PISO-1500 paleointensity record, suggesting that it might reflect the paleointensity variation of the geomagnetic field. The RPI record from the Xifeng section, where pedogenesis is rather strong, indicates a clear dissimilarity with the stacked PISO-1500 paleointensity record, implying that it does not reflect the paleointensity variation of the geomagnetic field. Our new results show that the NRM 300 /χ from the strongly pedogenetic paleosols does not completely eliminate the pedogenetic （climatic） influence, so it might be unsuitable for a reliable paleointensity study.

关键词： Chinese loess pedogenesis relative paleointensity rock magnetism geomagnetic field

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Liposome-Encapsulated Hemoglobin Vesicle Improves Persistent Anti-arrhythmogenesis through Improving Myocardial Electrical Remodeling and Modulating Cardiac Autonomic Activity in a Hemorrhagic Shock-Induced Rat Heart Model

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Current Medical Science 2023年第2期43卷 232-245页

作者： Bonpei Takase Yuko Higashimura Haruka Asahina masayuki Ishihara Hiromi Sakai Department of Intensive Care Medicine National Defense Medical CollegeTokorozawa359-8513Japan Division of Traumatology Research Institute National Defense Medical College Research InstituteTokorozawa359-8513Japan Division of Biomedical Engineering National Defense Medical College Research InstituteTokorozawa359-8513Japan Department of Chemistry School of MedicineNara Medical UniversityNara634-8521Japan

Objective Shock heart syndrome(SHS)is associated with lethal arrhythmias(ventricular tachycardia/ventricular fibrillation,VT/VF).We investigated whether liposome-encapsulated human hemoglobin vesicles(HbVs)has comparable persistent efficacy to washed red blood cells(wRBCs)for improving arrhythmogenesis in the subacute to chronic phase of *** Optical mapping analysis(OMP),electrophysiological study(EPS),and pathological examinations were performed on blood samples from Sprague-Dawley rats following induction of hemorrhagic *** hemorrhagic shock,the rats were immediately resuscitated by transfusing 5%albumin(ALB),HbV,or *** rats survived for 1 *** and EPS were performed on Langendorff-perfused *** arrhythmias and heart rate variability(HRV)were evaluated using awake 24-h telemetry,cardiac function by echocardiography,and pathological examination of *** OMP showed significantly impaired action potential duration dispersion(APDd)in the left ventricle(LV)in the ALB group whereas APDd was substantially preserved in the HbV and wRBCs *** VT/VF was easily provoked by EPS in the ALB *** VT/VF was induced in the HbV and wRBCs ***,spontaneous arrhythmias,and cardiac function were preserved in the HbV and wRBCs *** showed myocardial cell damage and Connexin43 degradation in the ALB group,all of which were attenuated in the HbV and wRBCs *** LV remodeling after hemorrhagic shock caused VT/VF in the presence of impaired *** to wRBCs,HbV persistently prevented VT/VF by inhibiting persistent electrical remodeling,preserving myocardial structures,and ameliorating arrhythmogenic modifying factors in the subacute to chronic phase of hemorrhagic shock-induced SHS.

关键词： artificial oxygen carrier hemorrhage lethal arrhythmia resuscitation heart rate variability

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Discovery of Paleozoic rocks at northern margin of Sambagawa terrane,eastern Kyushu,Japan:Petrogenesis,U-Pb geochronology and its tectonic implication

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Geoscience Frontiers 2020年第4期11卷 1441-1459页

作者： Kenta Kawaguchi Yasutaka Hayasaka Tomoyuki Shibata masayuki Komatsu Kosuke Kimura Kaushik Das Department of Earth and Planetary Systems Science Graduate School of ScienceHiroshima University1-3-1 KagamiyamaHigashi-HiroshimaHiroshima739-8526Japan Hiroshima Institute of Plate Convergence Region Research 1-3-1 KagamiyamaHigashi-HiroshimaHiroshima739-8526Japan Ehime University 10-13 Dogo-HimataMatsuyamaEhime790-8577Japan

Ordovician diorite-quartz diorite mylonite(Saganoseki quartz diorite) was discovered in Sambagawa metamorphic terrane at the northern margin of Saganoseki Peninsula,Kyushu Island,*** LA-ICP-MS zircon U-Pb geochronology revealed that the intrusion age of Saganoseki quartz diorite was 473.3±3.6 *** rocks show the volcanic arc affinity based on the trace element *** the basis of geochronological and geochemical results,Saganoseki quartz diorite is considered to be a member of the Early Paleozoic igneous rocks of the Kurosegawa tectonic *** quartz diorite is located just south of the Median Tectonic Line(MTL)and is in close contact with the pelitic and psammitic schist without any brittle shear zone.U-Pb ages of detrital zircon grains from two psammitic schists show the estimated sedimentation age of early Late Cretaceous,indicate that these psammitic schists are the member of Sambagawa metamorphic *** with these results and the mode of occurrence in the field,we argue that the Early Paleozoic igneous rocks of the Kurosegawa tectonic zone existed as an upper structural unit of the Sambagawa *** relationship is the key to reconstruct the Mesozoic tectonics of Japan as a part of East Asia,and its evolution through time.

关键词： Outer zone of southwest Japan Sambagawa metamorphic terrane Kurosegawa tectonic zone LA-ICP-MS zircon U-Pb age Saganoseki quartz diorite

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Design and Implementation of NAREGI SuperScheduler Based on the OGSA Architecture

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Journal of Computer Science & Technology 2006年第4期21卷 521-528页

作者： Satoshi Matsuoka masayuki Hatanaka Yasumasa Nakano Yuji Iguchi Toshio Ohno Kazushige Saga Hidemoto Nakada Global Scientific Information and Computing Center Tokyo Institute of Technology 2-12-10okayama Meguro-ku Tokyo 152-8550 Japan Center for Grid Research and Development National Institute of Informatics 1-105 Kanda-Jinbocho Chiyoda-ku Tokyo 101-0051 Japan Linux Software Development Div. Server Systems Unit. Fujitsu Limited 130 Miyamoto Numazu-shi Shizuoka410-0396 Japan Grid Technology Research Center National Institute of Advanced Industrial Science and Technology 1-18-13 Sotokanda Chiyoda-ku Tokyo 101-0021 Japan

NAREGI is a 5-year Japanese National Grid Project during 2003--2007, whose chief aim is to develop a set of grid middleware to serve as a basis for future e-Science. NAREGI also aims to lead the way in standardization of grid middleware, based on the OGSA architecture. Its super-scheduler is based on the proposed OGSA-EMS Architecture, in that it becomes the first working implementation that implements the documented component relationships within the OGSA-EMS architecture document v.l.0. Through the efforts and experience in the design and implementation, it has been confirmed that the documented OGSA-EMS architecture is quite feasible, but will require significant amount of refinement and speed improvements to finalize its detailed specifications. The super-scheduler also supports co-allocation across multiple sites to support automated execution of grid-based MPIs that execute across machines. Such a resource allocation requires sophisticated interactions between the OGSA-EMS components not covered in the current OGSA-EMS architecture, some of which are non-trivial. Overall, job scheduling with OGSA-EMS has proven to not only work, but also that its job allocation and execution time is within reasonable bounds.

关键词： grid scheduling resource management open grid services architecture OGSA

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Neoadjuvant treatment for esophageal squamous cell carcinoma

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World Journal of Gastrointestinal Oncology 2014年第5期6卷 121-128页

作者： Yoshifumi Baba masayuki Watanabe Naoya Yoshida Hideo Baba Department of Gastroenterological Surgery Graduate School of Medical Science Kumamoto University Department of Gastroenterological Surgery Cancer Institute Hospital Japanese Foundation for Cancer Research

Squamous cell carcinoma and adenocarcinoma are types of esophageal cancer, one of the most aggressive malignant diseases. Since both histological types present entirely different diseases with different epidemiology, pathogenesis and tumor biology, separate therapeutic strategies should be developed against each type. While surgical resection remains the dominant therapeutic intervention for patients with operable esophageal squamous cell carcinoma(ESCC), alternative strategies are actively sought to reduce the frequency of post-operative local or distant disease recurrence. Such strategies are particularly sought in the preoperative setting. Currently, the optimal management of resectable ESCC differs widely between Western and Asian countries(such as Japan). While Western countries focus on neoadjuvant or definitive chemoradiotherapy, neoadjuvant chemotherapy followed by surgery is the standard treatment in Japan. Importantly, each country and region has established its own therapeutic strategy from the results of local randomized control trials. This review discusses the current knowledge, available data and information regarding neoadjuvant treatment for operable ESCC.

关键词： Esophageal cancer Squamous cell carcinoma Neoadjuvant therapy

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Association between Diabetes Mellitus and Oral Health Status in Japanese Adults

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International Journal of Oral Science 2010年第2期2卷 82-89页

作者： masayuki Ueno Susumu Takeuchi Akiko Oshiro Kayoko Shinada Satoko Ohara Yoko Kawaguchi Department of Oral Health Promotion Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Department of Comprehensive Oral Health Care Faculty of Dentistry Tokyo Medical and Dental University

Aim The objective of this study was to analyze the oral health among Japanese adults, with and without diabetes mellitus. Methodology The subjects were 518 community residents aged 20 to 91 years in Japan, who participated in the ＂Akita health and nutrition survey＂ and the ＂Akita dental disease survey＂, conducted in 2006. The surveys comprised a self-administered questionnaire, along with medical and dental examinations. Results Using the community periodontal index （CPI）, the mean numbers of sextants presenting codes 0, 1 and 2 were significantly lower in diabetics than non-diabetics among the 59 years or younger age group. Although the mean numbers of sextants with codes 0, 1 and 2 among the 60 to 69 years age group were lower, and sextants with a code X among the 59 years or younger age group were higher in diabetics than non-diabetics, no statistically significant differences were detected. The tendency of lower mean numbers of natural teeth and functional tooth units in diabetics than non-diabetics was observed, however no differences were statistically significant. Conclusion The outcome of periodontal disease seemed to be influenced by the diabetic state to some degree, but a clear association between diabetes and oral health status was not found.

关键词： diabetes mellitus periodontal disease community periodontal index functional tooth units

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Gastric mixed adenoma-neuroendocrine tumor:A case report

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World Journal of Clinical Cases 2020年第22期8卷 5744-5750页

作者： Shuzo Kohno Hiroaki Aoki masayuki Kato Masaich Ogawa Kazuhiko Yoshida Department of Surgery The Jikei University Katsushika Medical CenterTokyo 125-8506Katsushika-kuJapan Department of Endoscopy The Jikei University Katsushika Medical CenterTokyo 125-8506Katsushika-kuJapan

BACKGROUND Gastric mixed adenoma-neuroendocrine tumors(NETs)are quite *** the 2019 world health organization classification of tumors of the digestive system,these were designated as a combination of grade 1 or grade 2 NETs and adenomas or tubular *** are no treatment guidelines for these tumors,and pathological and clinical studies are ***,we review previous case reports and present a case of gastric mixed *** SUMMARY A 66-year-old man underwent gastrointestinal endoscopy for the evaluation of upper abdominal *** examination of the biopsy specimen indicated the possibility of gastric cancer.A histopathological examination by endoscopic submucosal dissection showed a mixed adenoma-NET that was completely excised by endoscopic submucosal *** recurrence was observed on gastrointestinal endoscopy at the 6-mo *** Clinicians'awareness of this rare tumor is important for its timely diagnosis and treatment.

关键词： Adenoma Neuroendocrine tumor Diagnosis Pathology Stomach treatment Case report

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Hepatocellular carcinoma or interferon-based therapy history attenuates sofosbuvir/ribavirin for Japanese genotype 2 hepatitis C virus

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World Journal of Gastroenterology 2018年第13期24卷 1478-1485页

作者： Masayoshi Yada masayuki Miyazaki Kosuke Tanaka Akihide Masumoto Kenta Motomura Department of Hepatology Iizuka Hospital

AIM To investigate the real-world efficacy and safety of sofosbuvir/ribavirin(SOF/RBV) therapy for Japanese patients with genotype 2 hepatitis C virus(GT2-HCV).METHODS A total of 182 patients with GT2-HCV infection who received SOF/RBV therapy for 12 wk at our hospital were enrolled. The patients comprised 122 men and 60 women(age range: 17-84 years; mean age ± SD: 60.1 ± 12.1 years). Relationships between virological response and clinical data were examined by logistic regression analyses. RESULTS The proportions of patients with liver cirrhosis and history of hepatocellular carcinoma(HCC) were 29.0% and 17.3%, respectively. The proportion of patients with prior interferon(IFN)-based therapy was 25.6%. SOF/RBV therapy rapidly decreased HCV RNA levels. Several patients required RBV dose reduction because of anemia or fatigue. Four patients discontinued the therapy. The rates of sustained virological response at 12 wk after the end of treatment were 87.9%(intention to treat: 160/182) and 94.1%(per protocol: 159/169). Multivariate analyses showed that history of HCC or IFN-based therapy independently reduced the efficacy of SOF/RBV therapy. CONCLUSION SOF/RBV therapy for GT2-HCV is safe, highly tolerated, and effective. History of HCC or IFN-based therapy independently reduces the efficacy of this treatment.

关键词： Sofosbuvir Ribavirin Genotype 2 Hepatitis C virus Interferon-based therapy Hepatocellular carcinoma

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Production analysis of functionally distributed machines for underground mining

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International Journal of Mining Science and Technology 2016年第3期26卷 477-485页

作者： Fukui Rui Kusaka Kouhei Nakao masayuki Kodama Yuichi Uetake Masaaki Kawai Kazunari Department of Mechanical Engineering The University of Tokyo Komatsu Ltd.

Recent years, underground mining method is becoming popular because of its potentially high productivity and efficiency. In this method, a mining machinery; load haul dump(LHD), is used as both an excavator and a transporter of ore. This paper proposes a distributed system that realizes the excavation and transport functions with separated vehicles, an excavator and a transporter. In addition, this research proposes a mining map and configurations suitable for the proposed distributed system. To evaluate the productivity of the proposed system, a simulation environment has been developed. Analysis using the simulator reveals what performance factors of the excavator and the transporter have large impacts on the productivity. Simulation results also demonstrate the difference of potential between LHD system and the distributed system that can be explained based on their functions allocation.

关键词： Underground mining Mining machinery Autonomous system design Distributed system System configuration

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Efficacy of transanal drainage tube in preventing anastomotic leakage after surgery for rectal cancer: A meta-analysis

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World Journal of Gastrointestinal Surgery 2023年第6期15卷 1202-1210页

作者： Shiki Fujino Masayoshi Yasui masayuki Ohue Norikatsu Miyoshi Innovative Oncology Research and Regenerative Medicine Osaka International Cancer InstituteOsaka 541-8567Japan Department of Surgery Osaka International Cancer InstituteOsaka 541-8567Japan

BACKGROUND Anastomotic leakage(AL)following rectal cancer surgery is an important cause of mortality and *** transanal drainage tubes(TDTs)are expected to reduce the rate of AL,their preventive effects are *** To reveal the effect of TDT in patients with symptomatic AL after rectal cancer *** A systematic literature search was performed using the PubMed,Embase,and Cochrane Library *** included randomized controlled trials(RCTs)and prospective cohort studies(PCSs)in which patients were assigned to two groups depending on the use or non-use of TDT and in which AL was *** results of the studies were synthesized using the Mantel-Haenszel randomeffects model,and a two-tailed P value>0.05 was considered statistically *** Three RCTs and two PCSs were included in this *** AL was examined in all 1417 patients(712 with TDT),and TDTs did not reduce the symptomatic AL *** a subgroup analysis of 955 patients without a diverting stoma,TDT reduced the symptomatic AL rate(odds ratio=0.50,95%confidence interval:0.29–0.86,P=0.012).CONCLUSION TDT may not reduce AL overall among patients undergoing rectal cancer ***,patients without a diverting stoma may benefit from TDT placement.

关键词： Meta-analysis Drainage Transanal Anastomotic leakage Surgical stomas Rectal cancer

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