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Definitive palliation for neoplastic colonic obstruction using enteral stents:Personal case-series with literature review

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World Journal of Gastroenterology 2004年第5期10卷 758-764页

作者： Giuseppe Piccinni Anna Angrisano mario Testini G.Martino Bonomo Section of General Surgery Vascular Surgery and Clinical OncologyDepartment of Applications in Surgery of Innovative TechnologiesUniversity of Bari-School of Medicine-BariItaly

Acute colonic obstruction due to malignancies is an emergency that requires surgical *** patients or inoperable tumors require intestinal decompression that is a simple colostomy in almost all ***“manoeuvre” leads the patient to a percentage of moRality/morbidity and to a bad quality of life due to acceptance of *** introduction of enteral metal stent inserted endoscopically has,in our opinion,provided a new way to obtaining the definitive palliation of inoperable colo-rectal cancer with a simple *** reported our case-series and we analyzed the current literature and costs of treatments.

关键词： Stents Aged Aged, 80 and over Colonic Neoplasms Endoscopy Female Humans Intestinal Obstruction Male Palliative Care

Deep Learning and Time Series-to-Image Encoding for Financial Forecasting

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IEEE/CAA Journal of Automatica Sinica 2020年第3期7卷 683-692页

作者： Silvio Barra Salvatore mario Carta Andrea Corriga Alessandro Sebastian Podda Diego Reforgiato Recupero Department of Mathematics and Computer Science University of CagliariCagliari 09121Italy

In the last decade,market financial forecasting has attracted high interests amongst the researchers in pattern ***,the data used for analysing the market,and then gamble on its future trend,are provided as time series;this aspect,along with the high fluctuation of this kind of data,cuts out the use of very efficient classification tools,very popular in the state of the art,like the well known convolutional neural networks(CNNs)models such as Inception,Res Net,Alex Net,and so *** forces the researchers to train new tools from *** operations could be very time *** paper exploits an ensemble of CNNs,trained over Gramian angular fields(GAF)images,generated from time series related to the Standard&Poor's 500 index future;the aim is the prediction of the future trend of the ***.A multi-resolution imaging approach is used to feed each CNN,enabling the analysis of different time intervals for a single observation.A simple trading system based on the ensemble forecaster is used to evaluate the quality of the proposed *** method outperforms the buyand-hold(B&H)strategy in a time frame where the latter provides excellent *** quantitative and qualitative results are provided.

关键词： Convolutional neural networks(CNNs) ensemble of CNNs financial forecasting Gramian angular fields(GAF)imaging

Diabetes mellitus and Parkinson's disease:dangerous liaisons between insulin and dopamine

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Neural Regeneration Research 2022年第3期17卷 523-533页

作者： Angela De Iuliis Ennio Montinaro Giuseppe Fatati mario Plebani Carlo Colosimo Department of Medicine-DiMED University of PadovaItaly Department of Neurology Santa Maria University HospitalTerniItaly Italian Obesity Network TerniItaly Department of Medicine-DiMED University of PadovaPadovaItaly/Department of Laboratory Medicine-Hospital of PadovaPadovaItaly

The relationship between diabetes mellitus and Parkinson's disease has been described in several epidemiological studies over the 1960 s to *** studies have shown the possible functional link between insulin and dopamine,as there is strong evidence demonstrating the action of dopamine in pancreatic islets,as well as the insulin effects on feeding and cognition through central nervous system mechanism,largely independent of glucose *** used for the treatment of type 2 diabetes mellitus appear to be promising candidates for symptomatic and/or disease-modifying action in neurodegenerative diseases including Parkinson's disease,while an old dopamine agonist,bromocriptine,has been repositioned for the type 2 diabetes mellitus *** review will aim at reappraising the different studies that have highlighted the dangerous liaisons between diabetes mellitus and Parkinson's disease.

关键词： dopamine GLP-1 insulin Parkinson's disease type 2 diabetes mellitus

Plasma–wave interaction in helicon plasmas near the lower hybrid frequency

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Chinese Physics B 2022年第7期31卷 413-419页

作者： Yide Zhao Jinwei Bai Yong Cao Siyu Wu Eduardo Ahedo mario Merino Bin Tian Science and Technology on Vacuum Technology and Physics Laboratory Lanzhou Institute of PhysicsLanzhou 730000China School of Mechanical Engineering and Automation Harbin Institute of TechnologyShenzhen 518055China Equipo de Propulsi´on Espacial y Plasmas(EP2) Universidad Carlos III de Madrid28911 Legan´esSpain

We study the characteristics of plasma–wave interaction in helicon plasmas near the lower hybrid ***(0D)dispersion relation is derived to analyze the properties of the wave propagation and a 1D cylindrical plasma–wave interaction model is established to investigate the power deposition and to implement the parametric *** is concluded that the lower hybrid resonance is the main mechanism of the power deposition in helicon plasmas when the RF frequency is near the lower hybrid frequency and the power deposition mainly concentrates on a very thin layer near the ***,it causes that the plasma resistance has a large local peak near the lower hybrid frequency and the variation of the plasma density and the parallel wavenumber lead to the frequency shifting of the local *** is found that the magnetic field is still proportional to the plasma density for the local maximum plasma resistance and the slope changes due to the transition.

关键词： helicon plasmas lower hybrid frequency power deposition

Sphincteroplasty for anal incontinence

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Gastroenterology Report 2014年第2期2卷 92-97页

作者： Lorenzo Carlo Pescatori mario Pescatori Coloproctology Unit Parioli ClinicRomeItaly

Sphincteroplasty(SP)is the operation most frequently performed in patients suffering from moderate-to-severe anal incontinence(AI)who do not respond to conservative *** costly surgeries,such as artificial bowel sphincter(ABS)and electro-stimulated graciloplasty,have been more or less abandoned due to their high morbidity *** invasive procedures are widely used,such as sacral neuromodulation and injection of bulking agents,but both are costly and the latter may cure only mild *** early outcome of SP is usually good if the sphincters are not markedly denervated,but its effect diminishes over *** is more often performed for post-traumatic than for idiopathic *** may also be associated to the Altemeier procedure,aimed at reducing the recurrence rate of rectal prolapse,and may be useful when AI is due either to injury to the sphincter,or to a narrowed rectum following the procedure for prolapse and haemorrhoids(PPH)and stapled transanal rectal resection(STARR).The outcome of SP is likely to be improved with biological meshes and post-operative pelvic floor *** is more effective in males than in multiparous women,whose sphincters are often denervated,and its post-operative morbidity is *** conclusion,SP,being both low-cost and safe,remains a good option in the treatment of selected patients with AI.

关键词： anal incontinence sphincteroplasty sphincter plication pelvic floor repair

Mitochondrial phylogeography of the Iberian endemic frog Rana iberica,with implications for its conservation

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Current Zoology 2018年第6期64卷 755-764页

作者： Jose TEIXEIRA Helena GONCALVES Nuno FERRAND mario GARCIA-PARiS Ernesto RECUERO Centro Interdisciplinar de Investigacao Marinha e Ambiental (CIIMAR) Terminal de Cruzeiros do Porto de LeixoesMatosinhos 4450-208Portugal Centro de Investigacao em Biodiversidade e Recursos Geneticos (CIBIO-InBIO) Universidade do PortoRua Padre Armando QuintasVairao 4485-661Portugal Museu de Historia Natural e da Cieneia da Universidade do Porto (MHNC-UP) Praca Gomes TeixeiraPorto 4099-002Portugal Departamento de Biologia Faculdade de Ciencias da Universidade do PortoPorto 4099-002Portugal Museo Nacional de Ciencias Naturales (MNCN-CSIC) Calle de Jose Gutierrez Abascal2Madrid 28006Spain

Genetic characterization of species using phylogeographic approaches represents a basic reference to understand their evolutionary history as well as to identify conservation priorities to protect areas of particular interest regarding evolutionary *** in well-studied regions such information is lacking for the majority of species,including many endemic species with reduced distribution *** investigate the phylogeographic pattern of the Iberian frog Rana iberica,an endemic amphibian restricted to Central and North-Western Iberian *** mitochondrial sequences,we reconstruct the phylogeographic history of the species to test the effect of Quaternary climate changes on the evolutionary diversification of lineages,that is,the differentiation of mitochondrial lineages and the formation of genetic diversity melting pots,and integrate phylogeographic evidence for future conservation *** results indicate the existence of 3 main mitochondrial lineages differentiated during the Upper *** historical demographic analyses and climatic niche modeling show a strong effect of glacial climate changes,suggesting recurrent range contractions and *** such circumstances,differentiation took place most likely by isolation in allopatric interglacial *** lineage admixture in northern Portugal generated a broad mixed zone with highest nucleotide *** its particular evolutionary potential,its reduced distribution and eventual threats under current climate change scenario,conservation priorities should focus on the isolated lineage from Sierra de Guadalupe.

关键词： climate niche modeling conservation demography glacial refugia phylogeegraphy Amphibia

Natural history of cytomegalovirus infection in a series of patients diagnosed with moderate-severe ulcerative colitis

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World Journal of Gastroenterology 2011年第5期17卷 633-638页

作者： Valeria Criscuoli Maria Rosa Rizzuto Luigi Montalbano Elena Gallo mario Cottone Dibimis(Biomedical Department of Internal and Specialist Medicine) "V.Cervello" Hospital PalermoUniversity of Palermo Institute of Pathology."V.Cervello" Hospital Palermo Division of Gastroenterology "V.Cervello" Hospital Palermo

AIM： To evaluate the natural history of human cytomegalovirus （HCMV） infection in a series of 28 ulcerative colitis patients in whom the search for HCMV was positive. METHODS： A series of 85 patients with moderate-se- vere ulcerative colitis flare-up were evaluated for a HCMV search by performing a haematoxylin and eosin stain, immunohistochemical assay and nested polymerase chain reaction on rectal biopsies. Among 85 screened patients （19 of whom were steroid resistant/dependant）, 28 were positive for HCMV; after remission the patients were followed up clinically and histologically. RESULTS： Among the 22 patients with complete follow- up, in 8 （36%） patients HCMV-DNA persisted in the in- testinal specimens. Among the HCMV positive patients, 4 （50%） experienced at least one moderate-severeflare-up of colitis without evidence of peripheral HCMV. Among the 14 HCHV negative patients, 3 with pouches developed pouchiUs and 5 out of 11 （45%） experienced a colitis flare-up. CONCLUSION： Our preliminary results suggest that HCHV may remain in the colon afber an acute coltis flare- up despite remission; it seems that the virus is not responsible for the disease relapse.

关键词： Ulcerative colitis Cytomegalovirus Naturalhistory Polymerase chain reaction Outcome

Suspended sediment transport analysis in two Italian instrumented catchments

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Journal of Mountain Science 2016年第6期13卷 957-970页

作者： Adriana GARCIA-RAMA Stefano Giorgio PAGANO Francesco GENTILE mario Aristide LENZI Department of Land EnvironmentAgriculture and Forestry(TeSAF)University of PadovaAgripolis-Vialedell'Universita 16-35o20 Legnaro(PD)Italy Department of Agricultural and Environmental Science(DiSAAT) University of BariviaAmendola 165/A70126 BariItaly ApuliaBasin Authority SPper Casamassima km 370010 ValenzanoBariItaly

Suspended sediment transport in streams is an effective indicator of soil erosion at the watershed scale. This process was studied using the data obtained from two continuous monitoring stations installed in Italian watersheds, the Rio Cordon and Torrente CarapeUe. The catchments have substantially different climatic, morphological and land use characteristics. The Rio Cordon, a small Alpine watershed, has been monitored since 1986, while in the Torrente Carapelle, a medium-size Mediterranean watershed, the monitoring station has provided data since 2007. Several flood events with suspended sediment transport were isolated in the two catchments, excluding those determined by snowmelt in the Rio Cordon as this process does not affect the Carapelle watershed. Analysis of the events showed different behavior in terms of hysteresis loop trends between water discharge （m3 S-1） and suspended sediment concentration （g 1-1） values, as the Rio Cordon confirms clockwise relationships most frequently, while counter-clockwise trends represent the majority of cases for the Carapelle Torrent. The different behavior of the two watersheds was further analyzed by evaluating relationships between the main hydrological parameters related to suspended sediment transport. Runoff controls the total sediment budget in both catchments. In contrast, it was noted that the runoff process does not interfere in the magnitude of the suspended sediment transport in the Rio Cordon catchment, while variations due to the larger size of the catchment area characterize the events in the Carapelle watershed. Lastly, a flow peak threshold that determines the advance or delay of the hydrograph peak with respect to the sedigraph peak was established for the Carapelle Torrent, while it was not reported in the Rio Cordon.

关键词： Suspended sediment transport Continuous monitoring Hysteresis analysis Flowpeak threshold: Soil erosion

Use of oleaginous plants in phytotreatment of grey water and yellow water from source separation of sewage

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Journal of Environmental Sciences 2017年第5期29卷 274-282页

作者： Maria Cristina Lavagnolo mario Malagoli Luca Alibardi Francesco Garbo Alberto Pivato Raffaello Cossu Department of Industrial Engineering University of Padova via Lungargine Rovetta 8 35127 Padova Italy DAFNAE University of Padova viale dell'Universita 16 35020 Legnaro Italy

Efficient and economic reuse of waste is one of the pillars of modern environmental engineering. In the field of domestic sewage management,source separation of yellow（urine）,brown（faecal matter）and grey waters aims to recover the organic substances concentrated in brown water,the nutrients（nitrogen and phosphorous）in the urine and to ensure an easier treatment and recycling of grey waters. With the objective of emphasizing the potential of recovery of resources from sewage management,a lab-scale research study was carried out at the University of Padova in order to evaluate the performances of oleaginous plants（suitable for biodiesel production）in the phytotreatment of source separated yellow and grey waters. The plant species used were Brassica napus（rapeseed）,Glycine max（soybean）and Helianthus annuus（sunflower）. Phytotreatment tests were carried out using 20 L pots. Different testing runs were performed at an increasing nitrogen concentration in the feedstock. The results proved that oleaginous species can conveniently be used for the phytotreatment of grey and yellow waters from source separation of domestic sewage,displaying high removal efficiencies of nutrients and organic substances（nitrogen 〉 80%; phosphorous 〉 90%; COD nearly 90%）. No inhibition was registered in the growth of plants irrigated with different mixtures of yellow and grey waters,where the characteristics of the two streams were reciprocally and beneficially integrated.

关键词： Phytotreatment Sewage Source separation Decentralization Grey water Urine Energy crops