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Energy and AI 2024年第3期17卷 313-326页

作者： Justin Münch Jan Priesmann Marius Reich Marius Tillmanns Aaron Praktiknjo mario adam University of Applied Sciences Duesseldorf Centre of Innovative Energy SystemsMuensterstr.15640476 DuesseldorfGermany RWTH Aachen University E.ON Energy Research CenterChair for Energy System Economics(FCN-ESE)Mathieustrasse 1052074 AachenGermany

The energy sector faces rapid decarbonisation and decision-makers demand reliable assessments of the security of electricity supply. For this, detailed simulation models with a high temporal and technological resolution are required. When confronted with increasing weather-dependent renewable energy generation, probabilistic simulation models have proven. The significant computational costs of calculating a scenario, however, limit the complexity of further analysis. Advances in code optimization as well as the use of computing clusters still lead to runtimes of up to eight hours per scenario. However ongoing research highlights that tailor-made approximations are potentially the key factor in further reducing computing time. Consequently, current research aims to provide a method for the rapid prediction of widely varying scenarios. In this work artificial neural networks (ANN) are trained and compared to approximate the system behavior of the probabilistic simulation model. To do so, information needs to be sampled from the probabilistic simulation in an efficient way. Because only a limited space in the whole design space of the 16 independent variables is of interest, a classification is developed. Finally it required only around 35 min to create the regression models, including sampling the design space, simulating the training data and training the ANNs. The resulting ANNs are able to predict all scenarios within the validity range of the regression model with a coefficient of determination of over 0.9998 for independent test data (1.051.200 data points). They need only a few milliseconds to predict one scenario, enabling in-depth analysis in a brief period of time.

关键词： Security of electricity supply Probabilistic simulation Metamodeling Artificial neural networks Regression

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Status and prospects for symmetric organic redox flow batteries

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Journal of Energy Chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan C.adam Dyker Department of Chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

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Amyloid-β-induced disruption of axon-initial-segment mitochondria localization:consequences for TAU missorting in Alzheimer's disease pathology

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Neural Regeneration Research 2025年第5期20卷 1407-1408页

作者： Daniel adam Felix Langerscheidt Hans Zempel Institute of Human Genetics University Hospital CologneCologneGermany Center for Molecular Medicine Cologne(CMMC) University of CologneCologneGermany

TAU is a neuronal microtubule-associated protein preferentially located in *** a battery of neurodegenerative diseases termed"tauopathies,"including Alzheimer's disease (AD),TAU is missorted and abnormally phosphorylated,leading to filamentous accumulations of hyperphosphorylated TAU,a pathological hallmark and potential disease driver of AD and related tauopathies (Zempel,2024).

关键词： Alzheimer tau diseases

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Reassessing the AMPK-MTORC1 balance in autophagy in the central nervous system

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Neural Regeneration Research 2025年第11期20卷 3209-3210页

作者： Marta García-Juan mario Villa Irene Benito-Cuesta Lara Ordónez-Gutiérrez Francisco Wandosell Centro de Biología Molecular“Severo Ochoa”(CSIC-UAM) Nicolas Cabrera 1Universidad Autónoma de MadridMadridSpain Fisiología Animal Departamento de BiologíaFacultad de CienciasUniversidad Autónoma de MadridMadridSpain Department of Clinical Neuroscience CMM Karolinska Universitetssjukhuset SolnaStockholmSweden Departamento de Bioquímica y Biología Molecular Universidad Complutense de MadridMadridSpain Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas(CIBERNED) MadridSpain

Autophagy is a cellular degradation and recycling system,indispensable for cellular and organ development,homeostasis,and *** cellular process is evolutionarily highly conserved to quality control of many proteins and dysfunctional organelles,which finally recycle components as amino *** process is effective during normal physiology as part of anabolism and plays an additional important role during starvation(Dikic and Elazar,2018).Different types of autophagy have been chara cterized based on their dynamic,mechanism of action,target substrates,and protein *** of them are macroautophagy(hereafter called"autophagy"),microa utophagy,and chape rone-media ted autophagy(Fleming et al.,2022).

关键词： homeostasis system hereafter

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Heterogeneity of mature oligodendrocytes in the central nervous system

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Neural Regeneration Research 2025年第5期20卷 1336-1349页

作者： Chao Weng adam M.R.Groh Moein Yaqubi Qiao-Ling Cui Jo Anne Stratton G.R.Wayne Moore Jack P.Antel Neuroimmunology Unit Montreal Neurological Institute-HospitalDepartment of Neurology and NeurosurgeryMcGill UniversityMontrealQCCanada Department of Neurology Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous *** evidence has challenged the classical view of the functionally static mature oligodendrocyte and revealed a gamut of dynamic functions such as the ability to modulate neuronal circuitry and provide metabolic support to *** the recognition of potential heterogeneity in mature oligodendrocyte function,a comprehensive summary of mature oligodendrocyte diversity is *** delve into early 20th-century studies by Robertson and Río-Hortega that laid the foundation for the modern identification of regional and morphological heterogeneity in mature ***,recent morphologic and functional studies call into question the long-assumed homogeneity of mature oligodendrocyte function through the identification of distinct subtypes with varying myelination ***,modern molecular investigations,employing techniques such as single cell/nucleus RNA sequencing,consistently unveil at least six mature oligodendrocyte subpopulations in the human central nervous system that are highly transcriptomically diverse and vary with central nervous system *** and disease related mature oligodendrocyte variation denotes the impact of pathological conditions such as multiple sclerosis,Alzheimer's disease,and psychiatric ***,caution is warranted when subclassifying mature oligodendrocytes because of the simplification needed to make conclusions about cell identity from temporally confined *** studies leveraging advanced techniques like spatial transcriptomics and single-cell proteomics promise a more nuanced understanding of mature oligodendrocyte *** research avenues that precisely evaluate mature oligodendrocyte heterogeneity with care to understand the mitigating influence of species,sex,central nervous system region,age,and disease,

关键词： aging central nervous system diseases electron microscopy heterogeneity immunohistochemistry myelin sheath natural history neuroglia oligodendroglia single-cell gene expression analysis

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典型草原两种菊科植物生长对道路建设的响应

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生态学报 2025年

作者：王星奇赵欣周 GULRAIZ Ahmad 张育文李佳欣 BHARELDIN adam MERGA Daba Tuli 侯扶江草种创新与草地农业生态系统全国重点实验室兰州大学草地农业科技学院国家林业草原局西北退化草原生态修复与利用工程技术研究中心农业农村部草牧业创新重点实验室

近几十年来，由于道路网络的扩张和城市化的蓬勃发展，道路建设对典型草原的影响引起了广泛的关注。然而，道路类型和距离对植物种群生长的综合影响仍然知之甚少。因此，本研究以陇东黄土高原微温微干典型草原为研究对象，探讨了道路建... 详细信息

近几十年来，由于道路网络的扩张和城市化的蓬勃发展，道路建设对典型草原的影响引起了广泛的关注。然而，道路类型和距离对植物种群生长的综合影响仍然知之甚少。因此，本研究以陇东黄土高原微温微干典型草原为研究对象，探讨了道路建设（道路类型、距离）对菊科优势种茵陈蒿（Artemisia capillaris）和伴生种阿尔泰狗娃花（Aster altaicus）生长繁殖影响的驱动因素及其作用机制。结果表明，道路建设促进茵陈蒿的横向生长和无性繁殖，促进阿尔泰狗娃花的垂直生长和有性繁殖。阿尔泰狗娃花具有更强的更新潜力。普通公路茵陈蒿和阿尔泰狗娃花的地上生物量分别比其它两种道路平均高49%和27%，因此其对普通公路建设的响应更加敏感。此外，道路建设主要通过影响土壤进一步影响两个种群的地上生物量在群落中的占比。阿尔泰狗娃花的地上生物量及其在群落中的占比在距离20—35 m的范围存在明显阈值。因此需要注意将此范围内的植被保护和恢复措施与道路管理动态结合，影响植物生长繁殖，调控群落构建过程，以应对道路建设对种群和群落关系扰动的巨大挑战。

关键词：道路建设道路生态地上生物量生长权衡繁殖策略种间关系

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Sex ratio of mirid populations shifts in response to hostplant co-infestation or altered cytokinin signaling

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Journal of Integrative Plant Biology 2017年第1期59卷 44-59页

作者： Nora adam Theresa Erler mario Kallenbach Martin Kaltenpoth Grit Kunert Ian T.Baldwin Meredith C.Schuman Department of Molecular Ecology Max Planck Institute for Chemical Ecology Hans-Knoll-Straβe 8 07745 Jena Germany German Centre for Integrative Biodiversity Research (iDiv) Deutscher Platz5e 04103 Leipzig Germany Max Planck Research Group Insect Symbiosis Max Planck Institute for Chemical Ecology Hans-Knoll-Straβe 8 07745 Jena Germany Department of Biochemistry Max Planck Institute for Chemical Ecology Hans-Knoll-Straβe 8 07745 Jena Germany

Herbivore species sharing a host plant often compete. In this study, we show that host plant-mediated interaction between two insect herbivores-a generalist and a specialist-results in a sex ratio shift of the specialist＇s offspring. We studied demographic parameters of the specialist Tupiocoris notatus（Hemiptera： Miridae）when co-infesting the host plant Nicotiana attenuata（Solanaceae） with the generalist leafhopper Empoasca sp.（Hemiptera： Cicadellidae）. We show that the usually female-biased sex ratio of T. notatus shifts toward a higher male proportion in the offspring on plants coinfested by Empoasca sp. This sex ratio change did not occur after oviposition, nor is it due differential mortality of female and male nymphs. Based on pyrosequencing and PCR of bacterial 16 S rRNA amplicons, we concluded that sex ratio shifts were unlikely to be due to infection with Wolbachia or other known sex ratio-distorting endosymbionts. Finally, we used transgenic lines of *** to evaluate if the sex ratio shift could be mediated by changes in general or specialized host plant metabolites. We found that the sex ratio shift occurred on plants deficient in two cytokinin receptors（irCHK2/3）.Thus, cytokinin-regulated traits can alter the offspring sex ratio of the specialist ***.

关键词： Empoasca populations specialist offspring Hemiptera altered Nicotiana specialized Solanaceae transgenic

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Solid rocket propulsion technology for de-orbiting spacecraft

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Chinese Journal of Aeronautics 2022年第3期35卷 128-154页

作者： adam OKNINSKI Center of Space Technologies Lukasiewicz Research Network-Institute of AviationWarsaw 02-256Poland

This paper presents the topic of using solid rocket propulsion for de-orbiting spacecraft,in order to fulfil space debris mitigation *** benefits and disadvantages of using such means are discussed.A dedicated system can be implemented in the satellite design phase and shall be a key subsystem of platforms inserted into ***,semi-controlled and controlled de-orbit can be completed using solid rocket *** impact on the space debris environment is *** requirements for dedicated propellants and systems are *** the majority of presently developed rocket systems worldwide require high burn rates,several applications,including de-orbiting,benefit from solid propellants with decreased regression *** allows limiting spacecraft accelerations and loads during de-orbit ***,the requirement of minimising solid particle generation is *** technology from the Mercury and Gemini human spaceflight programmes,where de-orbit motors were used,is *** Soviet,American and Chinese film-return-capsule solid propellant retrorockets,enabling deorbit,are also presented.A detailed survey of current work worldwide on end-of-life disposal using solid propulsion is *** of developing dedicated systems are ***,an outlook on solid rocket motor utilisation for space debris mitigation is provided.

关键词： De-orbit De-orbiting technology End-of-life disposal Satellite propulsion system development Solid propellant Solid rocket motor Space debris mitigation Space traffic management

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Proactive interburden fracturing using UIS drilling with validation monitoring

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International Journal of Mining Science and Technology 2021年第1期31卷 3-7页

作者： adam Lines Anglo American Grosvenor MineMoranbah 4744Australia

A series of gas inrush events occurred during development at Grosvenor Mine resulting in exposure to elevated levels of methane at the production face.A total of 22 gas inrush events occurred,with between 15 and 130 m3 of methane released during each *** presence of an undrained seam in the immediate floor,geotechnical characteristics of the floor,and the stress environment all contributed to these dynamic floor events,while the geological characteristics of the seam below,such as the seam thickness and ash content of 75%,prevented effective ***,events only occurred in headings mined parallel to the principal horizontal stress *** cut-throughs(C/T)perpendicular to the principal stress direction no events occurred,and higher methane levels were observed at the production *** solution to preventing the gas inrush events involved creating a conduit in the interburden between the mined seam and the seam in the immediate floor to allow the gas to be drained during the development of the headings,as occurred in the cut-throughs(cut-through and cross-cut are regional terms that are analogous).A series of underground inseam(UIS)holes were drilled using the directional drill rig with the aim of fracturing this interburden ahead of the face and promote floor failure to allow the gas to release *** floor fracturing was conducted using water pressure generated from a longwall salvage pump,with the current UIS drilling equipment retrofitted with a series of subs,packers and a fracturing *** packers and the fracturing tool were shifted to desired locations along the drilled UIS borehole to achieve the required *** fractures were monitored using a proving hole and with a HYDAC data logger attached to the salvage pack,with the results analysed on the surface to ensure connectivity to the working seam.

关键词： Gas drainage Floor fracking UIS drilling

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A digital earth platform for sustainability

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International Journal of Digital Earth 2017年第4期10卷 342-355页

作者： mario Hernandez Engagement Committee Future EarthMexico CityMexico International Society for Digital Earth Mexico CityMexico

Based on the experience of the International Society for Digital Earth(ISDE),this paper describes some challenges foreseen in order to develop a Digital Earth platform that can support the implementation of the Sustainable Development *** use of ready-to-use derived geospatial information is *** Earth’s methodology of‘co-design’aims to bring together natural,social scientists and decision makers to plan and carry out research for *** implies transdisciplinary research,but in order for scientists of different disciplines to work together,they will need to be able to share,access and use common *** is by far not simple!While the good will to share data might exist,the associated technological,ethical and privacy issues are difficult to *** adequate e-infrastructure will be *** could consider to use the SDGs is the basis to develop the desired Digital Earth *** paper,by no means,covers everything for a Digital Earth platform,it aims to trigger research discussions and to have a good view about a starting point.

关键词： Digital earth platform sustainable development Sustainable Development Goals future earth

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