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Applying Earth Observation technologies to Economic Consequence Modeling:A Case Study of COVID‑19 in Los Angeles County,California

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International Journal of Disaster Risk Science 2024年第1期15卷 18-31页

作者： Fynnwin Prager marina t.mendoza Charles K.Huyck Adam Rose Paul Amyx Gregory Yetman Kristy F.tiampo California State University Dominguez HillsCarsonCA 90747USA ImageCat Inc.Long BeachCA 90802USA University of Southern California Los AngelesCA 90015USA CIESIN–Center for International Earth Science Information Network Columbia UniversityPalisadesNY 10964USA Cooperative Institute for Research in Environmental Sciences(CIRES) University of Colorado BoulderBoulderCO 80309USA

Earth observation(EO) technologies,such as very high-resolution optical satellite data available from Maxar,can enhance economic consequence modeling of disasters by capturing the fine-grained and real-time behavioral responses of businesses and the *** investigated this unique approach to economic consequence modeling to determine whether crowd-sourced interpretations of EO data can be used to illuminate key economic behavioral responses that could be used for computable general equilibrium modeling of supply chain repercussions and resilience *** applied our methodology to the COVID-19 pandemic experience in Los Angeles County,California as a case *** also proposed a dynamic adjustment approach to account for the changing character of EO through longer-term disasters in the economic modeling *** found that despite limitations,EO data can increase sectoral and temporal resolution,which leads to significant differences from other data sources in terms of direct and total impact *** findings from this analytical approach have important implications for economic consequence modeling of disasters,as well as providing useful information to policymakers and emergency managers,whose goal is to reduce disaster costs and to improve economic resilience.

关键词： Computable general equilibrium models COVID-19 Disaster economic impacts Earth observation Economic consequence analysis Los Angeles County

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Role of platelets and breast cancer stem cells in metastasis

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World Journal of Stem Cells 2020年第11期12卷 1237-1254页

作者： Gretel mendoza-Almanza Luis Burciaga-Hernandez Vilma Maldonado Jorge Melendez-Zajgla Jorge Olmos CONACYt Universidad Autónoma de Zacatecas.Zacatecas 98060Mexico Maestría en Ciencias Biomédicas Universidad Autónoma de ZacatecasZacatecas 98160Mexico Laboratorio de Epigenética Instituto Nacional de Medicina GenómicaCiudad de México 14610Mexico Génómica funcional del cáncer Instituto Nacional de Medicina GenómicaCiudad de México 14610Mexico Biotecnología marina Centro de Investigación Científica y de Estudios Superiores de EnsenadaEnsenada 22860Mexico

the high mortality rate of breast cancer is mainly caused by the metastatic ability of cancer cells,resistance to chemotherapy and radiotherapy,and tumor regression *** recent years,it has been shown that the presence of breast cancer stem cells is closely associated with the migration and metastatic ability of cancer cells,as well as with their resistance to chemotherapy and *** tumor microenvironment is one of the main molecular factors involved in cancer and metastatic processes development,in this sense it is interesting to study the role of platelets,one of the main communicator cells in the human body which are activated by the signals they receive from the microenvironment and can generate more than one *** can ingest and release RNA,proteins,cytokines and growth *** the platelets interact with the tumor microenvironment,they are called"tumor-educated platelets."tumor-educated platelets transport material from the tumor microenvironment to sites adjacent to the tumor,thus helping to create microenvironments conducive for the development of primary and metastatic *** has been observed that the clone capable of carrying out the metastatic process is a cancer cell with stem cell *** stem cells go through a series of processes,including epithelial-mesenchymal transition,intravasation into blood vessels,movement through blood vessels,extravasation at the site of the establishment of a metastatic focus,and site ***-educated platelets support all these processes.

关键词： Breast cancer stem cells Platelets Metastasis tumor microenvironment Epithelial-mesenchymal transition

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Adipose-derived mesenchymal stem/stromal cells:from the lab bench to the basic concepts for clinical translation

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BIOCELL 2018年第3期42卷 67-77页

作者： Yesica Romina FRONtINI-LóPEZ Aldana Daniela GOJANOVICH Diego MASONE Diego Martín BUStOS marina UHARt Laboratorio de Integración de Señles Celulares.IHEM-CONICEt Universidad Nacional de Cuyo MendozaArgentina Facultad de Ingeniería Universidad Nacional de CuyoMendozaArgentina Facultad de Ciencias Exactas y Naturales Universidad Nacional de CuyoMendozaArgentina

In the last years,much work has shown that the most effective repair system of the body is represented by stem cells,which are defined as undifferentiated precursors that own unlimited or prolonged self-renewal ability,which also have the potential to transform themselves into various cell types through *** tissues that form the body contain many different types of somatic cells,along with stem cells that are called‘mesenchymal stem(or stromal)cells’(MSC).In certain circumstances,some of these MSC migrate to injured tissues to replace dead cells or to undergo differentiation to repair *** discovery of MSC has been an important step in regenerative medicine because of their high ***,the finding of a method to isolate MSC from adipose tissue,so called‘adipose-derived mesenchymal stem cells’(ASC),which share similar differentiation capabilities and isolation yield that is greater than other MSC,and less bioethical concerns compared to embryonic stem cells,have created self-praised publicity to procure almost any treatment with ***,we review the current techniques for isolation,culture and differentiation of human ASC(hASC),and describe them in *** also compile some advantages of the hASC over other stem cells,and provide some concepts that could help finding strategies to promote their therapeutic efficiency.

关键词： hASC tissue regeneration Cell therapy

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Freely Available tool(FAt)for automated quantification of lipid droplets in stained cells

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BIOCELL 2017年第2期41卷 55-58页

作者： DIEGO MASONE ALDANA DGOJANOVICH YESICA R.FRONtINI-LOPEZ SAMANtA DEL VELIZ marina UHARt DIEGO M.BUStOS Laboratorio de Integración de Senales Celulares.IHEM-CONICEt Universidad Nacional de Cuyo MendozaArgentina Facultad de Ingeniería Universidad Nacional de CuyoMendozaArgentina Facultad de Ciencias Exactas y Naturales Universidad Nacional de CuyoMendozaArgentina

In this study,we propose an automatic procedure for digital image *** describe a method that can efficiently quantify and characterize lipid droplets distributions in different cell types in ***,the lipid droplets detection method described in this work could be applied to static or time-lapse data,collected with a simple visible light or fluorescence microscopy *** automated algorithms were implemented in Octave,a freely available scientific package.

关键词： Adipogenesis 3t3-L1 cells human stem cells automatic image processing

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Evaluation of Stress Corrosion Cracking Damage to an API 5L X52 Pipeline transporting Ammonia: A Case Study

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Materials Sciences and Applications 2016年第10期7卷 610-622页

作者： José Luis Mora-mendoza Mónica Jazmín Hernández-Gayosso Daniel Antonio Morales-Serrat Octaviano Roque-Oms Digna Alejandra Del Angel Gerardo Zavala-Olivares Petróleos Mexicanos Marina Nacional 329 Col. Petróleos Mexicanos CDMX Ciudad de México México Instituto Mexicano del Petróleo Eje Central Lázaro Cárdenas Norte 152 Col. San Bartolo Atepehuacan CDMX Ciudad de México México

the high number of leak events that took place in recent years at a 25.4 cm (10”)Øpipeline transporting anhydrous liquid ammonia, located in the Southeast of Mexico, was the main reason to carry out a number of field studies and laboratory tests that helped establish not only the failure causes but also mitigation and control solutions. the performed activities included direct evaluation at failure sites, total repair programs, metallographic studies and pipeline flexibility analyses. the obtained results were useful to conclude that the failures obeyed a cracking mechanism by Stress Corrosion Cracking (SCC) which was caused by the combined effect of different factors: high stress resistance, high hardness of the base metal with a microstructure prone to brittleness and residual strains originated during the pipeline construction. From the operative, logistic and financial standpoints, it is not feasible to release the stress of approximately 22 km of pipeline. therefore, the only viable solution is to install a new pipeline with suitable fabrication, construction and installation specifications aimed at preventing the SCC phenomenon.

关键词： Stress Corrosion Cracking Residual Stress Ammonia transporting Pipeline

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Sea Level Variation at Western Coast of Mexican Pacific in Response to tsunamigenic Earthquakes （2012-2015）

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Journal of Shipping and Ocean Engineering 2015年第6期5卷 318-326页

作者： Rom~in Rodolfo Vera-mendoza Modesto Ortiz-Figueroa Centro de Alerta de tsunamis Secretaria de Marina Av. Heroica Escuela Naval Militar No. 861. Col. Los Cipreses Del.Coyoacfn D.F. 04830 Mexico Centro de Investigaei6n Cientifica y Educaci6n Superior de Ensenada (CICESE) Km 107 Carretera Touana-Ensenada EnsenadaBaja California 22860 Mexico

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Variation for Health-Enhancing Compounds and traits in Onion (Allium cepa L.) Germplasm

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Food and Nutrition Sciences 2016年第7期7卷 577-591页

作者： E. marina Insani Pablo F. Cavagnaro Virginia M. Salomón Leandro Langman María Sance Adriana A. Pazos Fernando O. Carrari Olga Filippini Laura Vignera Claudio R. Galmarini INtA Food Technology Institute Hurlingham Argentina INtA Biotechnology Institute Hurlingham Argentina Cuyo National University Mendoza Argentina CONICEt Buenos Aires Argentina Luján National University Luján Argentina INtA EEA La Consulta La Consulta Argentina

Consumption of onion has been associated with reduced incidence of chronic diseases. Phenolic, organosulfur and carbohydrate compounds present are largely responsible for these effects. this study examined compositional variation for health-enhancing compounds in a genetically diverse collection of onion cultivars. total antioxidant activity and aroma profiles were characterized. Significant variation in bulb concentration for total and individual phenolic compounds, thiosulfinates, carbohydrates, and total and soluble solids was found. the range of variation was particularly large (>50-fold difference between the cultivars with the highest and lowest content) for fructo-oligosaccharides (FOS) and the polyphenols quercetin, epigallocatechin gallate and epicatechin gallate. Amino acid profiles varied significantly as well with substantial variation (~10 fold) observed in both total and essential amino acids. total antioxidant activity was positively correlated with polyphenols content, and quercetin in particular (r = 0.83), suggesting a major contribution from phenolic compounds to onion antioxidant properties. Significant positive correlation was also found between solids and thiosulfinates content (r = 0.74) and between solids and FOS (r = 0.81), suggesting a dilution/concentration effect for organosulfur compounds and FOS in onion bulbs. the present study revealed broad variation for health-enhancing compounds content in onion germplasm, which can be exploited in breeding programs aiming at increasing onion nutraceutical value.

关键词： Onion Polyphenols Carbohydrates Amino Acids Aroma Profiles

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