检索结果-南通市图书馆

A case of atypical neurological symptoms and high cerebro-spinal fluid acetone level due to transdermal exposure to isopropanol

在线全文

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2023年第2期14卷 152-154页

作者： Côme Fruit Sophie Guillotin marie Wolfrum Thomas Lanot Florent Battefort Pierre Girardie marie Rafiq Nicolas Delcourt Poison Control Center Toulouse University HospitalToulouse 31509France Neurology Department Toulouse University HospitalToulouse 31509France Pharmacokinetics and Toxicology Laboratory Federative Institute of BiologyToulouse University HospitalToulouse 31509France Poison Control Center and INSERM 1214 Toulouse University HospitalToulouse 31509France

Dear editor, Isopropanol, also named 2-propanol or isopropyl alcohol(IPA), is a colorless, volatile liquid found in numerous household chemicals, such as cleaners and disinfectants, which typically contain a 70% solut... 详细信息

关键词： acetone typically alcohol

3D models of dilated cardiomyopathy:Shaping the chemical,physical and topographical properties of biomaterials to mimic the cardiac extracellular matrix

在线全文

学校读者我要写书评

暂无评论

Bioactive Materials 2022年第1期7卷 275-291页

作者： marie Camman Pierre Joanne Onnik Agbulut Christophe Helary Sorbonne Universit´e CNRSUMR 7574Laboratoire de Chimie de la Matiere Condensee de Paris4 place Jussieu(case 174)F-75005ParisFrance Sorbonne Universite Institut de Biologie Paris-Seine(IBPS)CNRS UMR 8256Inserm ERL U1164Biological Adaptation and Ageing7 quai St-Bernard(case 256)F-75005ParisFrance

The pathophysiology of dilated cardiomyopathy(DCM),one major cause of heart failure,is characterized by the dilation of the heart but remains poorly understood because of the lack of adequate in vitro *** 2D models do not allow for the 3D organotypic organization of cardiomyocytes and do not reproduce the ECM *** this review,the different strategies to mimic the chemical,physical and topographical properties of the cardiac tissue affected by DCM are *** advantages and drawbacks of techniques generating anisotropy required for the cardiomyocytes alignment are *** addition,the different methods creating macroporosity and favoring organotypic organization are ***,the advances in the induced pluripotent stem cells technology to generate cardiac cells from healthy or DCM patients will be *** to the biomaterial design,some features of the DCM extracellular matrix such as stiffness,porosity,topography or chemical changes can impact the cardiomyocytes function in vitro and increase their *** mimicking the affected heart,both at the cellular and at the tissue level,3D models will enable a better understanding of the pathology and favor the discovery of novel therapies.

关键词： Biomaterials Dilated cardiomyopathies Induced pluripotent stem cells Porosity Anisotropy

High-magnification observation of seminiferous tubules through the tunica albuginea by two-photon laser scanning microscopy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2011年第5期13卷 774-776页

作者： Vincent Achard Pascal Weber Georges Mercier marie-Pierre Blanchard Laboratoire d＇Histologie-Cytologie Faculte de Medecine secteur Timone Universite de la Mediterranee Marseille 13385 France Centre d＇Assistance Medicale a la Procreation AP-HM Conception Marseille 13385 France CNRS - IBDML - UMR6216 Service Imagerie - Case 907 Faculte des Sciences de Luminy Marseille 13288 France and Centre de Microscopie et Imagerie IFR Jean Roche Universite de la Mediterranee Marseille 13916 France

Testicular sperm extraction is widely used in the treatment of male infertility in cases of non-obstructive azoospermia. Identifying spermatogenetic foci within the testes is critical for testicular sperm extraction. Two-photon laser scanning microscopy （TPLSM） is an autofluorescence-based microscopy technique that allows observation at a cellular level in the depth of fresh living tissues and does not require any histological processing （fixation or staining）. The wavelengths previously used have shown no phototoxicity on sperm. We used TPLSM to detect spermatogenetic foci in fresh mouse testicular parenchyma without disrupting the tunica albuginea. Fresh surgically retrieved testes were observed using TPLSM within 1 h after extraction. Contralateral testes for each animal were observed using standard histology. Using TPLSM we were able to observe and measure the diameter of seminiferous tubules through the tunica albuginea, similar to the histological control. Structures within epithelial tubules were also observed, although their nature has yet to be identified. TPLSM is a real-time microscopy technique that could detect spermatogenetic foci.

关键词： seminiferous epithelium spermatogenesis

Design and implementation of platform for embedded Ethernet control system

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

仪器仪表学报 2008年第6期29卷 1121-1128页

作者： Zhu Lingbo Lin-Shi Xue-Fang Dai Guanzhong Rétif Jean-marie College of Automation Northwestern Polytechnical University Xi＇an 710072 China l＇Ecole Doctorale： Electronique Electrotechnique Automatique (EEA) Institute National des Sciences Appliquées de Lyon Villeurbanne 69621 France

A platform named EMECS based on embedded Ethernet control system is implemented.A PC running Fedora 6(Linux2.6)works as a central controller.A kit running Linux 2.4 based on Samsung2410A(ARM920t core)works as a remote controller and a DC motor(ESCA P28HSL18-219/204)made by Portescap Company works as a ***,system modeling is presented by analyzing the characteristics of Ethernet and the plant,based on a proposed delay measurement ***,implementation of the system including program and hardware is described in *** then the delay is measured and the control results of the system are tested in three cases with different network loads as *** platform is proved to have flexibility of running different control algorithms and extensibility of adding *** results demonstrate the validity of the system.

关键词：以太网控制系统设计方案平台

PHYSIOPHARMACOLOGICAL ASPECTS OF PATHOLOGICAL PAIN STATES

在线全文

学校读者我要写书评

暂无评论

神经解剖学杂志 2001年第B7期17卷 17-21页

作者： Jean-marie BESSON INSERM UNITE 161 and EPHE 2 rue d'Alésia 75014 PARIS FRANCE PharmD DSc

Recordings in both animals and humans have identified various types of nociceptors. A large number of classification systems have been proposed. For example, in cutaneous tissue in man, the existence of unmyelinated polymodal nociceptors (conduction velocity<2m/sec) activated by mechanical, thermal and chemical stimuli have been clearly established. Similarly Aδ mechanothermal nociceptors and high threshold Aδ mechanoreceptors have been identified. The Aδ and C nociceptors have been clearly demonstrated in

关键词：疼痛头痛生理病理药理递质传导途径细胞因子受体

Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, france

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2012年第4期14卷 584-590页

作者： Cendrine Geoffroy-Siraudin Anderson Dieudone Loundou Fanny Romain Vincent Achard Blandine Courbibre marie-He1ene Perrard Philippe Durand marie-Roberte Guichaoua Reproduction Biology Laboratory Conception Hospital AP-HM Marseille 13005 France Aix-Marseille University UMR CNRS IMBE 7263 Faculty of medicine of Marseille Marseille 13005 France Department of medical information Conception Hospital AP-HM Marseille 147 Bd Baille Marseille 13005 France Health Laboratory Faculty of Medicine of Marseille Marseille 13005 France Centre of Assisted Reproductive Technique (CPMA) Conception Hospital AP-HM Marseille 13005 France Functional Genomic Institute of Lyon CNRS INRA ENS of Lyon Lyon 69007 France

Semen from 10 932 male partners of infertile couples was analysed and sperm parameter trends were evaluated at the Reproduction Biology Laboratory of the University Hospital of Marseille （france） between 1988 and 2007. After 3-6 days of abstinence, semen samples were collected. Measurements of seminal fluid volume, pH, sperm concentration, total sperm count, motility and detailed morphology of spermatozoa were performed. Sperm parameters were analysed on the entire population and in men with normal total numeration （〉~ 40 million per ejaculate）. The whole population demonstrated declining trends in sperm concentration （1.5% per year）, total sperm count （1.6% per year）, total motility （0.4% per year）, rapid motility （5.5% per year） and normal morphology （2.2% per year）. In the group of selected samples with total normal sperm count, the same trends of sperm quality deterioration with time were observed. Our results clearly indicate that the auality of semen decreased in this population over the study period.

关键词： environment male infertility regional differences semen quality sperm parameters

Effect of Dietary Incorporation of <i>Curcuma longa</i>Powder on Haematology and Serological Properties of Guinea Pigs (<i>Cavia porcellus</i>)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Animal Sciences 2020年第4期10卷 750-760页

作者： france Gina Djoumessi Tobou Fernand Tendonkeng Emile Miégoué Bertine marie Noel Noumbissi David Fokom Wauffo Hervé Mube Kuitche Dayan Ebile Agwah Department of Zootechnic Faculty of Agronomy and Agricultural Sciences University of Dschang Dschang Cameroon

The reduced efficiency of antibiotic growth promoters in livestock, and the unavoidable residual effects on livestock products such as egg, meat and milk have pushed researchers to rush towards the use of phytobiotics in animal feed. This study was conducted at the Teaching and Research Farm of the University of Dschang to evaluate the Effect of Cucurma longa powder as feed additive on hemato-serological parameters in Guinea pigs. A total of 120 three weeks old Guinea pigs (60 males and 60 females), with an average weight of 150 ± 20 g were used. The animals were randomly distributed into four treatments in a completely randomized design with 30 animals per treatment (15 males and 15 females). Four experimental treatments were used by adding 0%, 0.25%, 0.5% and 1% C. longa in the diet corresponding to R0, R0.25%, R0.5% and R1% respectively. At the 8th week of age, 12 Guinea pigs (6 males and 6 females) per treatment were fasted for 12 hours and sacrificed by cervical dislocation. Blood was rapidly collected from the jugular vein for the evaluation of haematological and biochemical parameters. Results revealed that the inclusion of Curcuma longa at 0.25% significantly (p Curcuma longa powder at 0.25% as feed additive positively regulates blood serum parameters of Guinea pigs.

关键词： Cavia porcellus Cucurma longa Haematology and Serological Parameters

Tuning Intermolecular Interaction Between Lignin and Carbon Nanotubes in Fiber Composites–A Combined Experimental and Ab-Initio Modeling Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Renewable Materials 2018年第3期6卷 325-335页

作者： Jan Badorrek Michael Walter marie-Pierre Laborie Freiburger Materialforschungszentrum Stefan-Meier-Straße 21D-79104 Freiburg im BreisgauGermany Chair of Forest Biomaterials Werthmannstraße 6D-79085 Freiburg im BreisgauGermany Freiburg Center for Interactive Materials and Bioinspired Technologies(FIT) Georges-Köhler-Allee 105D-79110 Freiburg im BreisgauGermany Fraunhofer Institute for Mechanics of Materials(IWM) Wöhlerstraße 11D-79108 Freiburg im BreisgauGermany

Doping lignin with carbon nanotubes is a promising strategy for cost-effective high-performance carbon *** investigate the intermolecular interaction potential of CNT and organosolv lignin with two main ***,oxidized purified multiwalled carbon nanotubes(MWCNTs)and beech organosolv lignins and derivatives are analyzed with their Hansen solubility parameters(HSPs)to assess their mutual ***,dispersion-corrected density functional theory simulations of the interaction between model molecules and single-walled carbon nanotubes reveal the source of *** find that oxidation enables and enhances the interaction between carbon nanotubes and organosolv lignin experimentally,which is in agreement with the enhanced polar interaction found in the simulations.

关键词： CNT DFT Hansen solubility parameters lignin oxidation

Relationships between mucinous gastric carcinoma, MUC2 expression and survival

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第21期12卷 3324-3331页

作者： Emmanuelle Leteurtre Farid Zerimech Guillaume Piessen Agnès Wacrenier Xavier Leroy marie-Christine Copin Christophe mariette Jean-Pierre Aubert Nicole Porchet marie-Pierre Buisine INSERM U560 59045Lille cedexFrance Service d'Anatomie et Cytologie Pabologiques Pôle Biologie-Pathogie Pac Eurasanté.CHR-U de Lille59037 Lille cedexFrance Service de Biochimie et Biologie Moléculaire CHR-U de Lille59037 Lille cedexFrance Facultéde Médecine H.Warembourg 59045 Lille cedexFrance Service.de Chirurgie Digetive et Générale CAEB CHR-U de Lille59045 Lille cedexFrance

AIM:To investigate the expression of the four secreted gel-forming mucins(MUC2,MUCSAC,MUCSB and MUC6)in a series of gastric carcinomas,classified according Laurén's,Mulligan's,WHO and Goseki's classifications,with special attention to all the different components(major and minor)present in tumors and to follow up clinical ***:Expression of MUC2,MUC5AC,MUC5B and MUC6 was investigated using immunohistochemistry and in situ ***:Expression of secreted gel-forming mucins in gastric carcinoma was particularly complex,each mucin being not restricted to any histopathological type even considering all components(major and minor)present in a given *** was a worst survival in patients with a higher content of mucus(GosekiⅡorⅣ)and high positive MUC2 ***:Complexity of mucin gene expression patterns in gastric cancer may reflect a precise state of differentiation at the cell level not recognized in used morphologic classification *** expression of MUC2 was nevertheless associated with mucinous subtype of the WHO classification and with groupⅡof Goseki's classification identified by the major component of a particular *** quantity and quality of mucus were related to survival.

关键词： Gastric cancer Secreted gel-forming mucin MUC Immunohistochemistry in situ hybridization Survival