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International Journal of Automation and computing 2016年第4期13卷 350-363页

作者： Syeda mariam Muzammal Munam Ali Shah Si-Jing Zhang Hong-Ji Yang Department of Computer Science COMSATS Institute of Information Technology Islamabad Pakistan Department of Computer Science and Technology University of Bedfordshire Luton LU13JU UK Centre for Creative Computing Bath Spa University Bath BA2 9BN UK

With the rapidly escalating use of smart devices and fraudulent transaction of users＇ data from their devices, efficient and reliable techniques for authentication of the smart devices have become an obligatory issue. This paper reviews the security risks for mobile devices and studies several authentication techniques available for smart devices. The results from field studies enable a comparative evaluation of user-preferred authentication mechanisms and their opinions about reliability, biometric authentication and visual authentication techniques.

关键词： Smart devices security risks authentication biometric privacy.

PCR Targeting of Antibiotic Resistant Bacteria in Public Drinking Water of Lahore Metropolitan,Pakistan

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Biomedical and Environmental Sciences 2009年第6期22卷 458-463页

作者： ZAHOOR QADIR SAMRA mariam NASEEM SUMARIA JAVED KHAN NADIA DAR MUHAMMAD AMIN ATHAR Institute of Biochemistry and Biotechnology Quaid-i-Azam CampusUniversity of the PunjabLahore 54590Pakistan Jinnah Degree College for Women Mozang RoadLahorePakistan

Objective To investigate the prevalence of kanamycin （kan） and ampicillin （amp） resistant bacteria in public drinking water. Methods Bacteria containing kan and amp resistant genes were amplified by PCR and further characterized by colony hybridization and transformation studies. The genus of kan and amp resistant bacteria was determined with standard methods. Results Among the 625 drinking water samples, 400 contained kan and amp resistant bacteria and the percentage was 42.5% and 57.5%, respectively, which was further confirmed by the amplification of a 810 bp kan resistant gene and a 850 bp amp resistant gene. Of the 170 kan resistant bacteria, 90 were Gram negative and 80 were Gram positive. Of the 230 amp resistant bacteria, 160 were Gram negative while 70 were Gram positive. Salmonella, Shigella, Staphylococcus, Streptococcus, and *** were detected as 13%, 11%, 17%, 30%, and 29%, respectively. Bacterial strain DH5α transformed with plasmids isolated from kan and amp resistant bacteria confirmed that the antibiotic resistant genes were mediated by plasmids. Conclusion Drinking water is contaminated with kan and amp resistant bacteria due to poor sanitary conditions.

关键词： Kanamycin Ampicillin PCR Plasmid Colony hybridization

Endoscopic treatment of scarred polyps with a non-thermal device(Endorotor):A review of the literature

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World Journal of Gastroenterology 2024年第12期30卷 1706-1713页

作者： mariam Zaghloul Hameed Rehman Stefano Sansone Konstantinos Argyriou Adolfo Parra-Blanco Department of Hepatology Gastroenterology and Infectious DiseasesKafrelsheikh UniversitKafr-Elshikh 33516Egypt Department of Gastroenterology Service Nottingham City Hospital CampusNottingham University Hospitals NHS TrustNottingham NG51PBUnited Kingdom Department of Gastroenterology University Hospital of LarissaLarissa 41334Greece NIHR Nottingham Biomedical Research Centre Nottingham University Hospitals NHS Trust and University of NottinghamNottingham NG72UHUnited Kingdom

Endoscopic resection(ER)of colorectal polyps has become a daily practice in most endoscopic units providing a colorectal cancer screening program and requires the availability of local experts and high-end endoscopic *** procedures have evolved over the past few years from endoscopic mucosal resection(EMR)to more advanced techniques,such as endoscopic submucosal dissection and endo-scopic full-thickness *** resection and disease eradication are the ultimate goals of ER-based techniques,and novel devices have been developed to achieve these *** EndoRotor®Endoscopic Powered Resection System(Interscope Medical,Inc.,Northbridge,Massachusetts,United States)is one such *** EndoRotor is a powered resection tool for the removal of alimentary tract mucosa,including post-EMR persistent lesions with scarring,and has both CE Mark and FDA *** review covers available published evidence documenting the usefulness of EndoRotor for the management of recurrent colorectal polyps.

关键词： EndoRotor Scarred polyps Recurrent polyps Colorectal cancer Colorectal polyps

Formulation and evaluation of semisolid jelly produced by Musa acuminata Colla(AAA Group) peels

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Asian Pacific Journal of Tropical Biomedicine 2016年第1期6卷 55-59页

作者： Noor Azwani Mohd Rasidek mariam Firdhaus Mad Nordin Kamyar Shameli Malaysia-Japan International Institute of Technology Universiti Teknologi Malaysia Kuala Lumpur

Objective:To study the jelly formulation produced by Musa acuminata Colla(AAA Group) peels and evaluate its antioxidant properties which are related to the product ***:The formulations of peel jelly were established under two-level full factorial designs within two blocks and one center *** response optimizer,the amount of sugar and citric acid was obtained;hence,the peel jellies were *** evaluation of antioxidant properties was conducted by using total phenolic content(TPC)assay and 1,1 diphenyl-2-picrylhydrazyl(DPPH) free radical ***:The TPC of peel powder varied from 91.8 to 602.26 mg gallic acid equivalents/100 g dry weight,and 5%-7% peel jellies had phenolic content ranging from 29.38 to 48.31 mg gallic acid equivalents/100 g dry *** results of DPPH test indicated that at 10 mg/mL,the peel powder showed 89% DPPH inhibition,while 7% peel jelly prominently exhibited 84% DPPH *** correlation between DPPH IC50 value and TPC of peel powder as well as peel jelly was quite reasonably high with correlation coefficient ranging from 0.843 7 to ***:TPC can be used as an indicator in assessing the antioxidant activity of fruits and *** present investigation reveals that TPC is mainly responsible for DPPH free radical scavenging capacity.

关键词： Antioxidant activity Banana peel Jelly formulation Musa acuminata Colla Total phenolic content

Predicting post-operative pancreatic fistula:one size may not fit all

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Hepatobiliary Surgery and Nutrition 2021年第1期10卷 113-115页

作者： mariam F.Eskander Jordan M.Cloyd Department of Surgery Division of Surgical OncologyThe Ohio State University Wexner Medical CenterColumbusOHUSA

Post-operative pancreatic fistula(POPF)is a common and dangerous complication of pancreatic resection,occurring in 5-30%of *** is a significant source of morbidity and mortality,leading to prolonged hospital stays and increased healthcare costs(1).The most widely accepted definition of POPF comes from the International Study Group on Pancreatic Fistula(ISGPF).Initially created in 2005,this classification system for POPF was revised in 2016 such that POPF should be associated with a clinically relevant change in status,deeming what was originally defined as a Grade A fistula as a biochemical leak and grade B and C fistulas as clinically relevant(CR)fistulae(Table 1)(2).

关键词： fistula operative mortality

Terminology for a FAIR Framework for the Virus Outbreak Data Network-Africa

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Data Intelligence 2022年第4期4卷 698-723,1050页

作者： Ruduan Plug Yan Liang Aliya Aktau mariam Basajja Francisca Oladipo Mirjam van Reisen Leiden University 2331 GL Leidenthe Netherlands Kampala International University 260101 KampalaUganda Leiden University Medical Centre(LUMC) Leiden University1310 Leidenthe Netherlands

The field of health data management poses unique challenges in relation to data ownership, the privacy of data subjects, and the reusability of data. The FAIR Guidelines have been developed to address these challenges. The Virus Outbreak Data Network(VODAN) architecture builds on these principles, using the European Union’s General Data Protection Regulation(GDPR) framework to ensure compliance with local data regulations, while using information knowledge management concepts to further improve data provenance and interoperability. In this article we provide an overview of the terminology used in the field of FAIR data management, with a specific focus on FAIR compliant health information management, as implemented in the VODAN architecture.

关键词： Data management Distributed data Federated data Data governance FAIR Guidelines FAIR Data and Services FAIR Data Point FAIR framework

Metabolomics in drug discovery: Restoring antibiotic pipeline

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Asian Pacific Journal of Tropical Biomedicine 2023年第9期13卷 378-383页

作者： Faiza Azhar mariam Busharat Shah Rukh Arshad Chaudhary Zainab Waheed Muhammad Nauman Jamil Department of Pharmaceutical Chemistry Punjab University College of PharmacyUniversity of the PunjabLahorePakistan School of Medical Indigenous and Health SciencesUniversity of WollongongNew South WalesAustralia Department of General Surgery Lahore General HospitalLahorePakistan Department of Pharmaceutical Chemistry Hamza College of PharmacyLahorePakistan

Metabolomics has emerged as a valuable tool in drug discovery and development,providing new insights into the mechanisms of action and toxicity of potential therapeutic *** focuses on the comprehensive analysis of primary as well as secondary metabolites,within biological *** provides a comprehensive understanding of the metabolic changes that occur within microbial pathogens when exposed to therapeutic agents,thus allowing for the identification of unique metabolic targets that can be exploited for therapeutic *** approach can also uncover key metabolic pathways essential for survival,which can serve as potential targets for novel *** analyzing the metabolites produced by diverse microbial communities,metabolomics can guide the discovery of previously unexplored sources of *** review explores some examples that enable medicinal chemists to optimize drug structure,enhancing efficacy and minimizing toxicity via metabolomic approaches.

关键词： Metabolomics Infectious diseases Drug discovery Antibiotics Biomarkers

Are we ready for telemonitoring inflammatory bowel disease?A review of advances,enablers,and barriers

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World Journal of Gastroenterology 2023年第7期29卷 1139-1156页

作者： Javier Del Hoyo Mónica Millán Alejandro Garrido-Marín mariam Aguas Department of Gastroenterology La Fe University and Polytechnic HospitalValencia 46026Spain Department of Surgery La Fe University and Polytechnic HospitalValencia 46026Spain Health Research Institute La Fe La Fe University and Polytechnic HospitalValencia 46026Spain

This review summarizes the evidence about telemonitoring in patients with inflammatory bowel disease(IBD). To give an overview of the advances performed, as well as the enablers and barriers which favoured/hindered telemonitoring implementation. We performed a literature search in Pub Med, EMBASE, MEDLINE, Cochrane Database, Web of Science and Conference Proceedings. Titles and abstracts published up to September 2022 were screened for a set of inclusion criteria: telemonitoring intervention, IBD as the main disease, and a primary study performed. Ninety-seven reports were selected for full review. Finally, 20 were included for data extraction and critical appraisal. Most studies used telemonitoring combined with tele-education, and programs evolved from home telemanagement systems towards web portals through m Health applications. Web systems demonstrated patients’ acceptance, improvement in quality of life, disease activity and knowledge, with a good cost-effectiveness profile in the short-term. Initially, telemonitoring was almost restricted to ulcerative colitis, but new patient reported outcome measures, home-based tests and mobile devices favoured its expansion to different patients’ categories. However, technological and knowledge advances led to legal, ethical, economical and logistic issues. Standardization of remote healthcare is necessary, to improve the interoperability of systems as well as to address liability concerns and users’ preferences. Telemonitoring IBD is well accepted and improves clinical outcomes at a lower cost in the short-term. Funders, policymakers, providers, and patients need to align their interests to overcome the emerging barriers for its full implementation.

关键词： Inflammatory bowel disease Telemedicine Telemonitoring Information and communication technology Crohn´s disease Ulcerative colitis

Prevalence and antimicrobial resistance pattern of bacterial strains isolated from patients with urinary tract infection in Messalata Central Hospital, Libya

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Asian Pacific Journal of Tropical Medicine 2016年第8期9卷 749-754页

作者： Mahmoud A.Mohammed Tarig MS Alnour Osama M.Shakurfo mariam M.Aburass Department of Medical Laboratory Technology Faculty of Medical Technologies-Messalata Almergib University Department of Food Hygiene and Control Faculty of Veterinary Medicine Mansoura University Department of Medical Laboratory Technology Faculty of Medical Technologies-MessalataAlmergib University Department of Medical Laboratory Technology Faculty of Applied Medical Sciences University of Tabuk

Objective: To investigate the prevalence of urinary tract infection among patients at Messalata Central Hospital, Libya, to identify the causative bacteria, and to explore their resistance pattern to antimicrobials. Methods: A total number of 1 153 urine samples were collected from patients, who attended daily to Messalata Central Hospital, Libya, in a study extended for one year. Antimicrobial susceptibility testing and isolates typing were done using Phoenix BD(BD diagnostic). Resistance was confirmed manually using agar disk diffusion method. Results: Of the 1 153 urine samples tested, 160(13.9%) samples were positive, from which 17 different, solely Gram negative, uropathogens were identified. Escherichia coli were the most prevalent(55.6%) bacteria, followed by Klebsiella pneumoniae subspecies pneumoniae(16.3%), Proteus mirabilis(6.3%), Pseudomonas aeruginosa(5.6%), Enterobacter cloacae and Klebsiella oxytoca(2.5%, each), Citrobacter koseri and Providencia rettgeri(1.9%, each), Acinetobacter baumannii, Enterobacter aerogenes and Proteus vulgaris(1.3%, each), and Aeromonas caviae, Citrobacter freundii, Cronobacter sakazakii, Enterobacter amnigenus biogroup 2, Pseudomonas putida and Serratia marcescens(0.6%, each). The isolated uropathogens showed increased levels of resistance ranged from 10.5% to 64.5%, with an overall resistance of 28.9%. Amikacin was the most effective antimicrobial followed by Imipenem and Meropenem(0%, 0.6% and 2.5% resistance, respectively); while, Cephalothin and Ampicillin were the least(80.6% and 90.0% resistance, respectively) effective. Conclusions: The obtained results emphasized the emergence of highly resistant bacteria to most of tested antimicrobials and raise the alarm for physicians to change their treatment pattern depending on antimicrobial susceptibility results.

关键词： Urinary tract infection(UTI) Uropathogens Significant Bacteruria Antimicrobial susceptibility testing(AST) Antimicrobial resistance Enterobacteriaceae

Towards the Tipping Point for FAIR Implementation

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Data Intelligence 2020年第1期2卷 264-275页

作者： Mirjam van Reisen Mia Stokmans mariam Basajja Antony Otieno Ong’ayo Christine Kirkpatrick Barend Mons Liacs Institute of Advanced Computer Science Leiden UniversityLeidenThe Netherlands Tilburg School of Humanities and Digital Sciences Tilburg University901535000 LE TilburgThe Netherlands International Institute of Social Studies Erasmus University297762502 LT The HagueThe Netherlands San Diego Supercomputer Center University of California San DiegoSan Diego CA 92093USA Leiden University Medical Center Leiden2333 ZAThe Netherlands

This article explores the global implementation of the FAIR Guiding Principles for scientific management and data stewardship,which provide that data should be findable,accessible,interoperable and *** implementation of these principles is designed to lead to the stewardship of data as FAIR digital objects and the establishment of the Internet of FAIR Data and Services(IFDS).If implementation reaches a tipping point,IFDS has the potential to revolutionize how data is managed by making machine and human readable data discoverable for ***,this article examines the expansion of the implementation of FAIR Guiding Principles,especially how and in which geographies(locations)and areas(topic domains)implementation is taking place.A literature review of academic articles published between 2016 and 2019 on the use of FAIR Guiding Principles is *** investigation also includes an analysis of the domains in the IFDS Implementation Networks(INs).Its uptake has been mainly in the Western *** investigation found that implementation of FAIR Guiding Principles has taken firm hold in the domain of bio and natural *** achieve a tipping point for FAIR implementation,it is now time to ensure the inclusion of non-European ascendants and of other scientific *** from equal opportunity and genuine global partnership issues,a permanent European bias poses challenges with regard to the representativeness and validity of data and could limit the potential of IFDS to reach across continental *** article concludes that,despite efforts to be inclusive,acceptance of the FAIR Guiding Principles and IFDS in different scientific communities is limited and there is a need to act now to prevent dampening of the momentum in the development and implementation of the *** is further concluded that policy entrepreneurs and the GO FAIR INs may contribute to making the FAIR Guiding Principles more flexible in including different rese

关键词： FAIR Data Health Digital Health mHealth data-driven science FAIR Implementation Networks GO-FAIR