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The.Influe.ce.of Re.ote.Ische.ic Conditioning on Focal Brain Ische.ia in Rats

Journal of Be.avioral and Brain Scie.ce 2021年第6期11卷 131-142页

作者： maria e. kolpakova Anastasia A. Yakovle.a Ludmila S. Polyakova Laboratory of Pathophysiology Pavlov First State Medical University Saint-Petersburg Russia

De.pite.obvious progre.s in the.tre.tme.t of acute.forms of ische.ic stroke. the.risk of this condition re.ains unacce.tably high. Brain infarction in the.middle.ce.e.ral arte.y basin occurs in patie.ts with athe.oscle.osis. The.onse. of the.brain infarction is facilitate. by the.ce.sation of circulation (e.bolism) in conditions of insufficie.t collate.al circulation. The.e.te.t of the.infarct zone.is de.e.mine. by ne.ronal de.th and impaire. microcirculation. The.de.e.opme.t of ne. me.hods for e.fe.tive.targe.e. re.torative.stroke.the.apy is crucial for re.torative.tre.tme.t and re.ucing the.risk of mortality afte. stroke. Re.ote.ische.ic conditioning (RIC) is an approach to limiting re.e.fusion injury in the.ische.ic re.ion of the.brain afte. focal ische.ia. One.of the.most commonly use. in vivo mode.s in stroke.studie. is the.filame.t mode. of Middle.Ce.e.ral Arte.y Occlusion (MCAO) in rats. In our e.pe.ime.t, it was pe.forme. for 30 min (J. Koizumi) with subse.ue.t 48-hour re.e.fusion. Within the.first 24 hours afte. the.start of re.e.fusion se.e.al short e.isode. of ische.ia in low limbs we.e.induce.. Afte. 48 hours of re.e.fusion the.brains we.e.harve.te. and staine. with TTC. The. we.e.aluate. the.e.fe.t of RIC within 24 hours e. vivo in rats’ brains, as we.l as synde.an-1 plasma conce.tration. Infarct are. was asse.se. by me.ns of Image.Pro program with statistical analysis. Infarct volume. in the.mode. group (31.97% ± 2.5%) we.e.significantly highe. compare. to the.value. in the.RIC group 48 hours afte. ische.ia-re.e.fusion (13.6% ± 1.3%) (*P e.uction in the.are. of infarction afte. RIC is like.y due.to the.e.fe.t on the.re.ulation of collate.al blood flow in the.ische.ia are.. On the.se.ond day afte. ische.ia-re.e.fusion, tissue.swe.ling was re.uce. in the.RIC group compare. to the.mode. group. Analysis of the.ave.age.conce.tration of Synde.an-1 re.e.le. the.diffe.e.ce.be.we.n mode. and RIC groups. Synde.an-1, e.dothe.

关键词： Stroke Brain Infarction Ische.ia-Re.e.fusion Synde.an-1 Glycocalyx e.dothe.ial Dysfunction Middle.Ce.e.ral Arte.y Occlusion (MCAO) Re.ote.Ische.ic Conditioning (RIC)

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Calcium-se.sitive.prote.n MLC1 as a possible.modulator of the.astrocyte.functional state

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Ne.ral Re.e.e.ation Re.e.rch 2025年第7期20卷 2008-2010页

作者： e.e.a Ambrosini Ange.a Lanciotti maria Ste.ania Brignone De.artme.t of Ne.roscie.ce Istituto Superiore di SanitàRomeItaly

Astrocyte.,the.main population of glial ce.ls in the.ce.tral ne.vous syste.(CNS),e.e.t e.se.tial tasks for the.control of brain tissue.home.stasis,supporting ne.ron and othe. glial ce.l activity from the.de.e.opme.tal stage.to adult *** maintain the.optimal functionality of the.brain,astroglial ce.ls are.particularly committe. to re.cting to e.e.y change.in tissue.home.static conditions,from mild modifications of the.physiological e.vironme.t,a proce.s calle. astrocyte.activation,to the.more.se.e.e.alte.ations occurring in pathological situations causing astrocyte.re.ctivity or re.ctive.astrogliosis(e.cartin e. al.,2021).During the.e.re.ctive.state.,astrocyte. mount an active.progre.sive.re.ponse.e.compassing morphological,mole.ular,and inte.actional re.ode.ing,le.ding to the.acquisition of ne. functions and the.loss of othe.s,whose.inte.sity,duration,and re.e.sibility are.de.e.de.t on the.nature.of the.stimulus and re.ulate. in a conte.t-spe.ific manne..

关键词： alte.ations modulator maintain

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Bioe.gine.ring mode.s of fe.ale.re.roduction

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Bio-De.ign and Manufacturing 2020年第3期3卷 237-251页

作者： maria e.ubizarre.a Shuo Xiao De.artme.t of e.vironme.tal He.lth Scie.ce. Arnold School of Public HealthUniversity of South CarolinaColumbiaSC 29208USA De.artme.t of Pharmacology and Toxicology Ernest Mario School of PharmacyEnvironmental Health Sciences InstituteRutgers University170 Frelinghuysen RoadPiscatawayNJ 08854USA

The.fe.ale.re.roductive.syste. consists of the.ovarie.,the.fe.ale.gonads,and the.re.roductive.tract organs of the.fallopian tube.,ute.us,ce.vix,and *** functions to provide.hormonal support and anatomical structure.for the.production of ne. offspring.A numbe. of e.doge.ous and e.oge.ous factors can impact fe.ale.re.roductive.he.lth and fe.tility,including ge.e.ic vulne.ability,me.ications,e.vironme.tal e.posure.,age.nutrition,and *** date.due.to the.e.hical conce.ns of using human subje.ts in biome.ical re.e.rch,the.majority of studie. use.in vivo animal mode.s and 2D ce.l/tissue.culture.mode.s to study fe.ale.***,the.comple.ity and spe.ie. diffe.e.ce.of the.fe.ale.re.roductive.syste. in humans make.it difficult to compare.to those.of ***,the.monolaye.e. ce.ls culture. on flat plastics or glass lose.the.r 3D archite.ture.as we.l as the.physical and/or bioche.ical contacts with othe. ce.ls in ***,all re.roductive.organs do not work alone.but inte.conne.t with e.ch othe. and also with non-re.roductive.organs to support fe.ale.re.roductive.e.docrine.and syste.ic *** facts sugge.t that the.e.is an urge.t and unme. ne.d to de.e.op re.re.e.tative.e.fe.tive.and e.ficie.t in vitro mode.s for studying human fe.ale.*** prodigious advance.e.ts of bioe.gine.ring(e.g.,biomate.ials,3D printing,and organ-on-a-chip)allow us to study fe.ale.re.roduction in an e.tire.y ne. ***,we.re.ie. re.e.t advance. that use.bioe.gine.ring me.hods to study fe.ale.re.roduction,including the.bioe.gine.ring mode.s of the.ovary,fallopian tube.ute.us,e.bryo implantation,place.ta,and re.roductive.dise.se.

关键词： Fe.ale.re.roduction Bioe.gine.ring Biomate.ials 3D printing Microfluidics

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Kairomonal e.fe.t of se. phe.omone.compone.ts of two le.idopte.an olive.pe.ts on Trichogramma wasps

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Inse.t Scie.ce 2009年第2期16卷 131-136页

作者： Panos Milonas Basilios e. Mazome.os maria A. Konstantopoulou Che.ical e.ology and Natural Products Laboratory Institute of Biology National Centre of Scientific Research 'Demokritos' Attikis Greece

e.g parasitoids are.known to use.a wide.range.of che.icals, e.itte. by plants, host e.gs or adults, for host se.e.tion. The.e.fe.t of the.se. phe.omone.compone.ts of the.le.idopte.an olive.pe.ts Prays ole.e.（Le.idopte.a： Yponome.tidae. and Palpita unionalis （Le.idopte.a： Pyralidae. was studie. unde. laboratory conditions, on the.foraging be.aviour of the.e.g parasitoid Trichogramma ole.e.（Hyme.opte.a： Trichogrammatidae.. The.re. sponse.of T. ole.e.wasps to （Z）-7-te.rade.e.al and （e.-1 l-he.ade.e.al, major se. phe.o- mone.compone.ts ofP. ole.e.and P. unionalis re.pe.tive.y, de.e.de. on the.dose.of the.phe.omone.use. in a Y-tube.olfactome.e. bioassay. （e.-11-he.ade.e.al e.icite. maximum attraction （70%） at a dose.of 1 pg, while.a dose.of 100 pg （Z）-7-te.rade.e.al attracte. 80% of the.te.te. wasps. （e.-11-he.ade.e.yl ace.ate. the.se.ond se. phe.omone.compone.t of P. unionalis, and the.binary ble.d of（e.-i 1-he.ade.e.yl ace.ate. （e.-11-he.ade.e.al （7：3） we.e.not attractive.at the.e.dose.. The.re.ults of this re.e.rch are.discusse. in vie. that the. may be.conside.e. as alte.native. in the.biological control of the.e.pe.ts.

关键词： e.g parasitoids olive.pe.t se.ioche.icals Y-tube.olfactome.e.

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Re.ombination-Inde.e.de.t Me.hanisms and Pairing of Homologous Chromosome. during Me.osis in Plants

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Mole.ular Plant 2014年第3期7卷 492-501页

作者： Olivie. Da Ine. maria e. Galle.o Charle. I. White Ge.e.ique Reproduction et Developpement UMR CNRS 6293 Clermont UniversitY INSERM U1103 63171 Aubiere France

Me.osis is the.spe.ialize. e.karyotic ce.l division that pe.mits the.halving of ploidy ne.e.sary for game. toge.e.is in se.ually re.roducing organisms, This involve. a single.round of DNA re.lication followe. by two succe.sive.divisions. To e.sure.balance. se.re.ation, homologous chromosome.pairs must migrate.to opposite.pole. at the.first me.otic division and this me.ns that the. must re.ognize.and pair with e.ch othe. be.ore.and. Although unde.standing of the.me.hanisms by which me.otic chromosome. find and pair with the.r homologs has gre.tly advance., it re.ains far from be.ng fully unde.stood. With some.notable.e.ce.tions such as male.Drosophila, the.re.ognition and physical link- age.of homologs at the.first me.otic division involve. homologous re.ombination. Howe.e., in addition to this, it is cle.r that many organisms, including plants, have.also e.olve. a se.ie. of re.ombination-inde.e.de.t me.hanisms to facili- tate.homolog re.ognition and pairing. The.e.implicate.chromosome.structure.and dynamics, te.ome.e., ce.trome.e., and, most re.e.tly, small RNAs. With a particular focus on plants, we.pre.e.t he.e.an ove.vie. of unde.standing of the.e.e.rly, re.ombination-inde.e.de.t e.e.ts that act in the.pairing of homologous chromosome. during the.first me.otic division,

关键词： me.osis homolog pairing chromatin ce.trome.e. te.ome.e..

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Forward： Proce.dings of the.2008 e.ological and e.olutionary e.hology of Fishe. Confe.e.ce. Boston, Massachuse.ts, USA

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Curre.t Zoology 2010年第1期56卷 I0001-I0002页

作者： maria e. ABATe.Gue.t e.itor De.artme.t of Biology Boston University Boston Massachusetts 02215 USA.

This spe.ial issue.of Curre.t Zoology conce.ning the.be.avior, e.ology, and e.olution of fishe. is comprise. of the.pe.r-re.ie.e. Proce.dings of the.2008 e.ological and e.olutionary e.ology of Fishe. Bie.nial Confe.e.ce.that was he.d June.29 - July 3 at Boston Unive.sity, Boston, Massachuse.ts, USA. The.confe.e.ce.and its four symposia we.e.organize. by a local organization committe. and scie.tific program committe. which include. maria Abate. host at Boston Unive.sity; Sigal Balshine. McMaste. Unive.sity; Michae. Clancy, Boston Unive.sity; Ronald Cole.an, California State.Unive.sity, Sacrame.to; John Godwin, North Carolina State.Unive.sity; Le. Kaufinan, Boston Unive.sity;

关键词：波士顿大学马萨诸塞州美国加州行为学生态鱼类进化学术委员会

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Cumulative.e.fe.ts of volcanic ash on the.food pre.e.e.ce. of two Orthopte.an spe.ie.

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Inse.t Scie.ce 2017年第4期24卷 640-646页

作者： Vale.ia Fe.n&nde.-Arhe. maria e. Amadio Octavio A. Bruzzone Instituto Nacional de.Te.nologia Agrope.uaria Estacion Experimental Agropecuaria-Bariloche CC277 A v Modesta Victoria 4450 (8400) San Carlos de Bariloche Argentina Lab ECO TONO-INIBIOMA Pie. Gutierrez 850 San Carlos de Bariloche Rio Negro Argentina Ce.tro Cie.tifico Te.nologico - Conse.o Nacional de.Inve.tigacione. Cie.tificas y Tocnicas (CCT-CONICe.) Patagonia Norte. Av. de.los Pione.os 2350 San Carlos de Bariloche Rio Negro Argentina

Ine.t dusts are.an e.rly form of inse.ticide.which is still in use. One.of the.most common ine.t dusts is volcanic ash. In orde. to study the.re.ction ofrange.and grasshoppe.s, Dichroplus vittige.um （Acrididae. and a katydid, t]wgilis me.dose.sis （Phane.opte.idae., to the.pre.e.ce.of volcanic ash in the.r food source. and how this re.ction change. as a function of time. we.conducte. paire. pre.e.e.ce.te.ts be.we.n cle.n le.ve. of the.r pre. fe.re. host plant and le.ve. e.pose. to volcanic ash of diffe.e.t grain size. The.be.avioral re.ponse.was me.sure. as the.rating on the.Thurstonian pre.e.e.ce.scale.of le.ve. with ash in re.ation to cle.n le.ve.. The.re.ults showe. that the.avoidance.of volcanic ash incre.se. as a function of time.in both spe.ie.. Both spe.ie. studie. are.occasionally e.pose. to vol- canic activity, and come.from an are. in which a volcanic e.uption had re.e.tly occurre.. As the.r populations did not de.re.se.afte. the.ash fall, we.propose.that some.be.avioral re.ponse. such as avoidance.of place. with ash, works as tole.ance.me.hanism to ine.t dusts e.posure.

关键词： Burgilis me.dose.sis Dichroplus vittige.um ine.t dust pre.e.e.ce.te.t thurstone.scale

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Advance. ce.e.t base. nanocomposite. re.nforce. with MWCNTs and CNFs

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Frontie.s of Structural and Civil e.gine.ring 2016年第2期10卷 142-149页

作者： e.manue. e. GDOUTOS maria S. KONSTA-GDOUTOS Panagiotis A. DANOGLIDIS Sure.dra P. SHAH De.artme.t of Civil e.gine.ring Democritus University of Thrace GR 671 O0 Xanthi Greece Northwe.te.n Unive.sity Evanston IL 60208 USA

Ce.e.titious mate.ials re.nforce. with we.l dispe.se. multiwall carbon nanotube. （MWCNTs） and carbon nanofibe.s （CNFs） at the.nanoscale.we.e.fabricate. and te.te.. The.MWCNTs and CNFs we.e.dispe.se. by the.application of ultrasonic e.e.gy and the.use.of a supe.plasticize.. Me.hanical and fracture.prope.tie. including fle.ural stre.gth, Young＇s modulus, fle.ural and fracture.toughne.s we.e.me.sure. and compare. with similarly proce.se. re.e.e.ce.ce.e.t base. mixe. without the.nano-re.nforce.e.t. The.MWCNTs and CNFs re.nforce. mortars e.hibite. supe.ior prope.tie. de.onstrate. by a significant improve.e.t in fle.ural stre.gth （106%）, Young＇s modulus （95%）, fle.ural toughne.s （105%）, e.fe.tive.crack le.gth （30%） and fracture.toughne.s （120%）.

关键词： multi-walle. carbon nanotube. carbon nanofibe.s mortars toughne.s Young's modulus

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Forward:Proce.dings of the.2008 e.ological and e.olutionary e.hology of Fishe. Confe.e.ce.Boston,Massachuse.ts,USA

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Curre.t Zoology 2010年第1期56卷 3-4页

作者： maria e.ABATe De.artme.t of Biology Boston University

This spe.ial issue.of Curre.t Zoology conce.ning the.e.avior, e.ology, and e.olution of fishe. is comprise.of the.pe.r-re.ie.e. Proce.dings of the.2008 e.ologicaland e.olutionary e.ology of Fishe. Bie.nial Confe.e.ce.hat was he.d June.29-July 3 at Boston Unive.sity,Boston, Massachuse.ts, USA. The.confe.e.ce.nd its four symposia we.e.organize. by a local organi-

关键词： Forward

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Mitochondrial inorganic polyphosphate.polyP):the.missing link of mammalian bioe.e.ge.ics

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Ne.ral Re.e.e.ation Re.e.rch 2021年第11期16卷 2227-2228页

作者： Bre.dan McIntyre.maria e.Sole.io De.artme.t of Biology Rutgers UniversityCamdenNJUSA

Bioe.e.ge.ics imbalance.is a de.e.e.ious fe.ture.which is pre.e.t in the.e.iopathology of many human dise.se.,including in diabe.e.,cance.,and ***,targe.ing the.compone.ts of mammalian bioe.e.ge.ics,as we.l as the.me.hanisms that re.ulate.the.re.ationship be.we.n the.e.compone.ts,could be.a promising pharmacological strate.y against a wide.varie.y of *** for many ye.rs mammalian bioe.e.ge.ics has be.n e.clusive.y circumscribe. to the.mitochondrial oxidative.phosphorylation(OXPHOS),which is the.main me.hanism to obtain ade.osine.triphosphate.ATP)in mammals,and to the.cytoplasmic glycolysis and the.close.y re.ate. pe.tose.phosphate.pathway,in the.last fe. de.ade. many authors have.advocate. for e.panding this te.m to include.all the.me.hanisms that are.involve. in matching the.ce.lular de.ands and production of e.e.gy to me.t the.ne.ds of the.ce.l unde. diffe.e.t state.,including physiological and pathological *** broade. de.inition will include.othe. ke. e.e.gy me.abolite.,such as the.ubiquitous inorganic polyphosphate.polyP).

关键词： inorganic dise.se. pathology

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