Recombination-Independent Mechanisms and Pairing of Homologous Chromosomes during Meiosis in Plants

作     者：Olivier Da Ines Maria E. Gallego Charles I. White 

作者机构：Genetique Reproduction et Developpement UMR CNRS 6293 Clermont UniversitY INSERM U1103 63171 Aubiere France 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2014年第7卷第3期

页      面：492-501页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 09[农学] 071009[理学-细胞生物学] 0901[农学-作物学] 0902[农学-园艺学] 

基　　金：partly financed by a European Union research grant the Centre National de la Recherche Scientifique, the Universite Blaise Pascal the Universite d'Auvergne and the Institut National de la Sante et de la Recherche Medicale 

主　　题：meiosis homolog pairing chromatin centromeres telomeres. 

摘      要：Meiosis is the specialized eukaryotic cell division that permits the halving of ploidy necessary for game- togenesis in sexually reproducing organisms, This involves a single round of DNA replication followed by two successive divisions. To ensure balanced segregation, homologous chromosome pairs must migrate to opposite poles at the first meiotic division and this means that they must recognize and pair with each other beforehand. Although understanding of the mechanisms by which meiotic chromosomes find and pair with their homologs has greatly advanced, it remains far from being fully understood. With some notable exceptions such as male Drosophila, the recognition and physical link- age of homologs at the first meiotic division involves homologous recombination. However, in addition to this, it is clear that many organisms, including plants, have also evolved a series of recombination-independent mechanisms to facili- tate homolog recognition and pairing. These implicate chromosome structure and dynamics, telomeres, centromeres, and, most recently, small RNAs. With a particular focus on plants, we present here an overview of understanding of these early, recombination-independent events that act in the pairing of homologous chromosomes during the first meiotic division,