检索结果-南通市图书馆

Indirect contact matters:Mid-flight external trunk perturbation increased unilateral anterior cruciate ligament loading variables during jump-landings

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2023年第4期12卷 534-543,F0003页

作者： Yu Song Ling Li Jacob Layer Raychl Fairbanks maddy Jenkins Gerwyn Hughes Derek Smith margaret Wilson Qin Zhu Boyi Dai Division of Kinesiology and Health University of WyomingLaramieWY 82071USA Department of Kinesiology University of San FranciscoSan FranciscoCA 94117USA Department of Theatre and Dance University of WyomingLaramieWY 82071USA

Purpose:To determine the effect of unanticipated mid-flight medial-lateral external perturbation of the upper or lower trunk on anterior cruciate ligament(ACL)loading variable s during ***:Thirty-two participants performed double-leg vertical jump-landings while bilateral kinematics and kinetics were collected under 6conditions(upper or lower trunk perturbation locations;no,left,or right perturbation directions).Two customized catapult apparatuses were created to apply pushing perturbation to participants near the maximal jump ***:The ball contacted participants near the center of mass for the lower-trunk conditions and approximately 23 cm above the center of mass for the upper-trunk *** upper-trunk perturbation,the contralateral leg demonstrated significantly smaller knee flexion angles at initial contact and greater peak knee abduction angles,peak vertical ground reaction forces,peak knee extension moments,and peak knee adduction moments compared to other legs among all *** lower-trunk perturbation,the contralateral leg showed significantly smaller knee flexion angles at initial contact and increased peak vertical ground reaction forces and peak knee extension moments compared to legs in the no-perturbation ***:Mid-flight external trunk pushing perturbation increased ACL loading variables for the leg contralateral to the *** uppertrunk perturbation resulted in greater changes in ACL loading variables compared to the lower-trunk perturbation,likely due to trunk and ipsilateral leg rotation and more laterally located center of mass relative to the contralateral *** findings may help us understand the mechanisms of indirect-contact ACL injuries and develop jump-landing training strategies under mid-flight trunk perturbation to better prevent ACL injury.

关键词： ACL injuries Biomechanics Kinematics Kinetics Landing

基于VRGIS的城市道路交通微观仿真系统研究

在线全文

学校读者我要写书评

暂无评论

中国海洋大学学报（自然科学版） 2010年第7期40卷 136-140页

作者：王春李文马纯永韩勇陈戈 margaret Horne 中国海洋大学信息科学与工程学院山东青岛266100 诺森比亚大学建筑与环境学院

将GIS技术和虚拟现实技术运用到城市交通仿真系统的微观仿真研究中,在城域景观VRGIS一体化仿真平台基础上建立了城市道路交通微观仿真系统,通过标准化数据模型完成GIS输入交通仿真数据,利用VR技术实现交通仿真的三维可视化,以一种人机... 详细信息

将GIS技术和虚拟现实技术运用到城市交通仿真系统的微观仿真研究中,在城域景观VRGIS一体化仿真平台基础上建立了城市道路交通微观仿真系统,通过标准化数据模型完成GIS输入交通仿真数据,利用VR技术实现交通仿真的三维可视化,以一种人机交互模式实现虚拟城市环境中的交通微观仿真。该系统用于英国纽卡斯尔市中心重建项目的方案评价中,通过对3种规划方案的优劣对比,为交通管理部门提供一定的决策支持。

关键词：虚拟地理信息系统虚拟现实微观交通仿真交通模型

体内和体外生物测定在环境监测中的应用(英文)

在线全文

学校读者我要写书评

暂无评论

化学进展 2009年第2期21卷 483-491页

作者： margaret B.Murphy 林忠华林群声香港城市大学生物及化学系中国香港

生物测定在环境毒物学研究中普遍用于检测人为污染物对个别生物体和生态系统的影响。这些测定适用于个别化学品或复杂的混合物(如废水)对有代表性的生物系统或整个生物体所引起的影响,并普遍应用于环境监测项目。生物测定可在生物体外... 详细信息

生物测定在环境毒物学研究中普遍用于检测人为污染物对个别生物体和生态系统的影响。这些测定适用于个别化学品或复杂的混合物(如废水)对有代表性的生物系统或整个生物体所引起的影响,并普遍应用于环境监测项目。生物测定可在生物体外或生物体内进行,前者是在实验室内利用细胞培养技术,后者除可在实验室内进行还可应用在真实的环境中。体外生物测定往往是用来研究环境样品中的污染物对生物机制的具体影响,如受体结合特性,而体内活性生物测定则提供了一个更加具体化的综合生物反应。然而,这两种类型的生物测定法可以测量许多不同的生物指标,如对生物生长及发育的影响、内分泌功能和DNA损伤。无论是在体内和体外生物测定都分别有其特有的优点和缺点,其中一些测定法可以使用于毒性鉴定和评价程序。本文简要介绍了体内和体外生物测定方法的基本特点及其在环境监测中的应用实例,指出化学物质如何影响有机体及生态系统的结构和功能,认为广泛发展更能充分反映生态系统生物多样性的生物测定方法,将有助于更准确地了解环境污染物对环境的潜在影响。

关键词：生物测定环境监测污染物在体外在体内生态系统

Emerging roles of circular RNAs in retinal diseases

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第9期17卷 1875-1880页

作者： Aneliya Hanineva Karen Sophia Park Joshua J.Wang margaret M.DeAngelis Michael H.Farkas Sarah X.Zhang Department of Ophthalmology and Ross Eye Institute Jacobs School of Medicine and Biomedical SciencesUniversity at BuffaloState University of New YorkBuffaloNYUSA Research Service Veterans Administration Western New York Healthcare SystemBuffaloNYUSA Department of Biochemistry Jacobs School of Medicine and Biomedical SciencesUniversity at BuffaloState University of New YorkBuffaloNYUSA

Retinal disorders are a group of ocular diseases whose onset is associated with a number of aberrant molecular and cellular processes or physical damages that affect retinal structure and function resulting in neural and vascular degeneration in the *** research has primarily focused on delaying retinal disease with minimal success in preventing or reversing neuronal *** this review,we explore a relatively new field of research involving circular RNAs,whose potential roles as biomarkers and mediators of retinal disease pathogenesis have only just *** knowledge of circular RNAs function is limited given its novelty,current evidence has highlighted their roles as modulators of microRNAs,regulators of gene transcription,and biomarkers of disease development and ***,we summarize how circular RNAs may be implicated in the pathogenesis of common retinal diseases including diabetic retinopathy,glaucoma,proliferative vitreoretinopathy,and age-related macular ***,we explore the potential of circular RNAs as novel biomarkers and therapeutic targets for the diagnosis and treatment of retinal diseases.

关键词： age-related macular degeneration circular RNA diabetic retinopathy glaucoma microRNA proliferative vitreoretinopathy retina

Monoclonal antibody-based cancer therapies

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2021年第2期34卷 301-307页

作者： Yingnan Si Arin L.Melkonian Keegan C.Curry Yuanxin Xu maranda Tidwell Mingming Liu Ahmed F.Zaky Xiaoguang(margaret)Liu Department of Biomedical Engineering University of Alabama at Birmingham(UAB)1825 University BlvdBirminghamAL 35294USA Department of Medicine UAB17202nd Ave S.BirminghamAL 35294USA Chinese Medicine Hospital 98 Shengcheng StreetShouguang 262700China Department of Anesthesiology and Perioperative Medicine UAB62519th Street SouthBirminghamAL 35294USA

Targeted therapy has been widely demonstrated as an effective strategy to treat cancers,the leading cause of death in the *** minireview summarizes the technical platforms and methodologies utilized to develop and engineer therapeutic monoclonal antibodies and antibody-drug ***,the USA FDA approved monoclonal antibody(mab)-based targeted therapies are *** the representative innovative chimeric,humanized and fully human anti-cancer antibodies and antibody-drug conjugates are ***,the past and predictive market trend of therapeutic antibodies is discussed.

关键词： Monoclonal antibody Antibody-drug conjugate Anti-cancer therapy market

The Global boundary Stratotype Section and Point （GSSP） of the Drumian Stage （Cambrian） in the Drum Mountains, Utah, USA

在线全文

学校读者我要写书评

暂无评论

Episodes 2007年第2期30卷 85-95页

作者： Loren E. Babcock Richard A. Robison margaret N. Rees Shanchi Peng matthew R. Saltzman School of Earth Sciences The Ohio State University 125 South Oval Mall Columbus OH 43210 USA. Department of Geology University of Kansas Lawrence KS 66045 USA. Department of Geoscience University of Nevada Las Vegas Las Vegas NV 89145 USA. State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and Palaeontology Chinese Academy of Sciences 39 East Beijing Road Nanjing 210008 China.

The Global boundary Stratotype Section and Point （GSSP） for the base of the Drumian Stage （Cambrian Series 3） is defined at the base of a limestone （calcisiltite） layer 62 m above the base of the Wheeler Formation in the Stratotype Ridge section, Drum Mountains, Utah, USA. The GSSP level contains the lowest occurrence of the cosmopolitan agnostoid trilobite Ptychagnostus atavus （base of the P. atavus Zone）. Secondary global markers near the base of the stage include the DICE negative δ^13C excursion, the onset of a long monotonic ^87Sr/^86Sr isotopic shift, and the transgressive phase of a eustatic event. Faunal turnovers close to the base of the Drumian Stage are recognized as the base of the Bolaspidella Zone （polymerid trilobites） in Laurentia, the historic base of the Floran Stage in Australia, the base of the Dorypyge richthofeni Zone （polymerid trilobites） in South China, and the base of the Gapparodus bisulcatus-Westergaardodina brevidens Assemblage-zone （conodonts） in Baltica and South China. The last occurrence of the cosmopolitan trilobite Ptychagnostus gibbus occurs in the lower part of the Drumian Stage, and the base of the Hydrocephalus hicksii Zone （polymerid trilobites） as used in Siberia and Baltica occurs near the base of the stage.

关键词：寒武纪地球边界犹他州美国地层类型

临界装置实验keff的不确定度分析及装置模型化处理

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

原子能科学技术 2017年第5期51卷 803-810页

作者：刘晓波 John D.Bess margaret A.marshall 中广核久源(成都)科技有限公司四川成都610093 中国工程物理研究院核物理与化学研究所四川绵阳621900 Idaho National Laboratory Idaho Falls 83415

将临界装置实验数据进行基准化分析并形成满足国际临界安全分析评价标准的基准实验数据,可充实临界安全实验基准数据库,进而可应用于核数据检验、数值模拟程序验证、反应堆设计和临界安全分析等领域。本文阐述了临界装置实验keff的不确... 详细信息

将临界装置实验数据进行基准化分析并形成满足国际临界安全分析评价标准的基准实验数据,可充实临界安全实验基准数据库,进而可应用于核数据检验、数值模拟程序验证、反应堆设计和临界安全分析等领域。本文阐述了临界装置实验keff的不确定度分析原理及处理方法、装置模型化要求及处理方法。然后采用该方法根据3个高浓铀圆环(内含石墨圆柱)临界装置的基本条件和实验结果,完成了实验keff的不确定度分析和装置模型化处理时的偏倚分析,得到了这3个临界装置在模型化处理后的keff值及不确定度。研究结果满足国际临界安全基准数据库收录的要求。

关键词：金属高浓铀石墨临界安全不确定度分析模型化处理基准分析

Stroke and Constipation<br/>—Coincidence or Interrelated?

在线全文

学校读者我要写书评

暂无评论

Health 2014年第19期6卷 2743-2748页

作者： Jayaprada Kasaraneni margaret Hayes Department of Family Medicine Oregon Health & Science University Portland OR USA

Emile Gautier once said, “Freedom of the bowels is the most precious, perhaps even the most essential, of all freedoms—one without which little can be accomplished.” This paper will explore the neuronal physiology, pathophysiology, theories regarding the correlation between stroke and constipation along with a few treatment options. Patients often recovering from stroke complain of constipation and it is most likely attributed to changes in diet, ambulation, or fluid balance. However, there are not many studies to reflect the correlation between other less significant symptoms and stroke presentation.

关键词： Stroke Constipation Treatment of Constipation Studies on Stroke

Intolerable Cruelty： marriage, Law, and Society in Early Twentieth-Century China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of History in China 2014年第3期9卷 475-478页

作者： margaret Mih Tillman Purdue University

In Intolerable Cruelty： marriage, Law, and Society in Early Twentieth-Century China, margaret Kuo argues that legal reforms allowed wives in the Republican era unprecedented opportunities to leave abusive or undesirable marriages. In addition to reevaluating Republican-era law, Kuo significantly contributes to scholarship by acknowledging the agency of the wives who brought forth their cases in court. In contrast to CCP scholarship that ＂has worked to expunge GMD contributions＂ to women＇s rights and family law （p. 12）, Kuo argues that the Republican era offered flexible solutions during ＂an important transitional period＂（19. 198）.

关键词：