Monoclonal antibody-based cancer therapies

作     者：Yingnan Si Arin L.Melkonian Keegan C.Curry Yuanxin Xu Maranda Tidwell Mingming Liu Ahmed F.Zaky Xiaoguang(Margaret)Liu Yingnan Si;Arin L.Melkonian;Keegan C.Curry;Yuanxin Xu;Maranda Tidwell;Mingming Liu;Ahmed F.Zaky;Xiaoguang(Margaret) Liu

作者机构：Department of Biomedical EngineeringUniversity of Alabama at Birmingham(UAB)1825 University BlvdBirminghamAL 35294USA Department of MedicineUAB17202nd Ave S.BirminghamAL 35294USA Chinese Medicine Hospital98 Shengcheng StreetShouguang 262700China Department of Anesthesiology and Perioperative MedicineUAB62519th Street SouthBirminghamAL 35294USA 

出 版 物：《Chinese Journal of Chemical Engineering》 (中国化学工程学报（英文版）)

年 卷 期：2021年第34卷第2期

页      面：301-307页

核心收录：

学科分类：0710[理学-生物学] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 1002[医学-临床医学] 0817[工学-化学工程与技术] 0703[理学-化学] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported by National Institutes of Health R21CA226491-01A1 (X.M.L.) 1R01CA238273-01A1 (X.M.L.) and 1R01CA242917-01A1(X.M.L.) 

主　　题：Monoclonal antibody Antibody-drug conjugate Anti-cancer therapy Market 

摘      要：Targeted therapy has been widely demonstrated as an effective strategy to treat cancers,the leading cause of death in the *** minireview summarizes the technical platforms and methodologies utilized to develop and engineer therapeutic monoclonal antibodies and antibody-drug ***,the USA FDA approved monoclonal antibody(mAb)-based targeted therapies are *** the representative innovative chimeric,humanized and fully human anti-cancer antibodies and antibody-drug conjugates are ***,the past and predictive market trend of therapeutic antibodies is discussed.