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Tracheobronchial Polyflex stents for the management of benign refractory hypopharyngeal strictures

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World Journal of Gastroenterology 2012年第6期18卷 551-556页

作者： Rui Almeida Silva Nuno Mesquita Pedro Pimentel Nunes Elisabete Cardoso Ricardo marcos Pinto luís Moreira dias Department of Gastroenterology Instituto Português de Oncologia do Porto Francisco GentilR.Doutor António Bernardino de Almeida 4200-072PortoPortugal Department of Gastroenterology Centro Hospitalar do PortoLargo Prof.Abel Salazar 4099-001PortoPortugal

AIM:To describe a modified technique for placement of a tracheobronchial self-expanding plastic stent(SEPS) in patients with benign refractory hypopharyngeal strictures in order to improve dysphagia and allow stricture ***:A case series of four consecutive patients with complex hypopharyngeal strictures after combinedtherapy for laryngeal cancer,previously submitted to multiple sessions of dilation without lasting improvement,is *** patients underwent placement of a small diameter and unflared tracheobronchial *** outcome measurements were improvement of dysphagia and avoiding of repeated ***:The modified introducer system allowed an easy and technically successful deployment of the tracheobronchial Polyflex stent through the *** four patients developed complications related to stent *** patients had stent migration(one proximal and one distal),two patients developed phanryngocutaneous fistulas and all patients with stents in situ for more than 8 wk had hyperplastic tissue growth at the upper end of the *** recurrence was observed at 4 wk follow-up after stent removal in all patients CONClUSION:Although technically feasible,placement of a tracheobronchial SEPS is associated with a high risk of *** diameter stents must be kept in place for longer than 3 mo to allow adequate time for stricture remodeling.

关键词： larynx neoplasms Hypopharynx Strictures Dilation Stents

Mortality Trends for Neglected Tropical Diseases in the State of Sergipe,Brazil,1980-2013

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Infectious Diseases of Poverty 2017年第1期6卷 173-180页

作者： marcos Antonio Costa de Albuquerque Danielle Menezes dias lucas Teixeira Vieira Carlos Anselmo lima Angela Maria da Silva University Hospital Federal University of SergipeRua Claudio Batista s/nB.Santo AntonioAracajuSE 49060-108Brazil Post-doc Medicine Unit Federal University of SergipeRua Claudio Batista s/nB.Santo AntonioAracajuSE 49060-108Brazil

Background:Neglected Tropical Diseases are a set of communicable diseases that affect the population so low socioeconomic status,particularly 1.4 billion people who are living below the poverty *** study has investigated the magnitude and mortality time trends for these diseases in the state of Sergipe,Northeast Region of ***:We conducted an ecological study of time series,based on secondary data derived from the Mortality Information System of the Ministry of *** mortality rates(crude,age-standardized rates and proportional ratio)were calculated from the deaths due to Neglected Tropical Diseases in the state of Sergipe,from 1980 to *** time trends were obtained using the Joinpoint regression ***:Three hundred six thousand and eight hundred seventy-two deaths were certified in the state and Neglected Tropical Diseases were mentioned as the underlying cause in 1,203 certificates(0.39%).Mean number of deaths was 35.38 per year,and crude and age-standardized mortality rates were,respectively:2.16 per 100000 inhabitants(95%CI:1.45-2.87)and 2.87 per 100000 inhabitants(95%CI:1.93-3.82);the proportional mortality ratio was 0.41%(95%CI:0.27-0.54).In that period,Schistosomiasis caused 654 deaths(54.36%),followed by Chagas disease,with 211(17.54%),and by leishmaniases,with 142(11.80%)*** other diseases totalized 196 deaths(16.30%).There were increasing mortality trends for Neglected Tropical Diseases,Schistosomiasis and Chagas disease in the last 15 years,according to the age-standardized rates,and stability of the mortality trends for ***:The Neglected Tropical Diseases show increasing trends and are a real public health problem in the state of Sergipe,since they are responsible for significant mortality *** following diseases call attention for showing greater number of deaths in the period of study:Schistosomiasis,Chagas disease and *** finally suggest that public managers take appropri

关键词： Mortality Neglected tropical diseases Trends Joinpoint

First Record in Brazil of Epistylis sp. (Ciliophora) Adhered to Argulus sp. (Argulidae), a Parasite of Hoplias aimara (Eritrhinidae)

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Natural Resources 2016年第6期7卷 331-336页

作者： lincoln lima Corrêa marcos Sidney Brito Oliveira luiza Prestes marcos Tavares-dias Universidade Federal do Oeste do Pará (UFOPA) Instituto de Ciências e Tecnologia das águas (ICTA) Santarém Brasil Programa de Pós-Gradua&ccedil &atilde o em Recursos Aquáticos Continentais Amazô nicos (PPGRACAM) Universidade Federal do Oeste do Pará (UFOPA) Instituto de Ciências e Tecnologia das águas (ICTA) Santarém Brasil Programa de Pós-Gradua&ccedil &atilde o em Ecologia Aquática e Pesca (PPGEAP) Universidade Federal do Pará (UFPA) Belém Brasil Embrapa Amapá Rodovia Juscelino Kubitschek Macapá Brasil

This paper records the first occurrence of Epistylis sp. on the body surface of Argulus sp. parasitizing Hoplias aimara from the upper Araguari River, in the eastern Amazon region, in the north of Brazil. Of the 16 specimens of H. aimara examined, 93.7% had their pelvic, caudal and pectoral fins and tegument infested by Argulus sp. (n = 73), which in turn were infested by Epistylis sp. The specimens of Epistylis sp. from the body surface of Argulus sp. were analyzed using Scanning Electron Microscopy (SEM). The present study also identified a widening of the geographic distribution of these two species of ectoparasites to the eastern Amazon region of Brazil.

关键词： Parasite Ecology Opportunistic Parasite Rio Araguari Eastern Amazon

Thermal and Crystallization Behavior of PlA/PllA-Grafting Cellulose Nanocrystal

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Materials Sciences and Applications 2020年第1期11卷 44-57页

作者： Erika M. Inácio Diego H. S. Souza marcos l. dias Instituto de Macromoléculas Professora Eloisa Mano (IMA) Universidade Federal do Rio de Janeiro (UFRJ) Rio de Janeiro Brazil

PllA-modified cellulose nanocrystals (CNC) were produced from commercial CNC by tin-catalyzed polymerization of lactide in presence of CNC. FTIR spectroscopy demonstrated that the result of the reaction produced the grafting of PllA chains onto CNC surface (CNC-g-PllA). Films of poly(lactic acid) (PlA) and PlA/CNC nanocomposites (with non-modified CNC and CNC-g-PllA) containing 0.5% and 5% (w/w) of the nanofillers were prepared by casting in chloroform solution and the crystallization behavior and thermal properties investigated. All nano-composites had similar thermal stability when analyzed by TGA analyses under an inert nitrogen atmosphere. Addition of both types of CNC influenced crystallization, the higher crystallization rate being observed for 5% (w/w) CNC. Nanocomposites with 5% (w/w) CNC-g-PllA had the strain resistance of PlA improved in the rubbery state. PllA-modification of CNC surface increased the crystallization of PlA in PlA/CNC nanocomposites and improved the rigidity at temperatures above the glass transition, properties which are desirable for hot drinking application.

关键词： Nanocrystals Cellulose Poly(lactic Acid) Grafting Crystallizations

Metazoan Parasites of <i>Geophagus proximus</i>, a Cichlidae Fish from the Eastern Amazon (Brazil)

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Natural Resources 2017年第3期8卷 268-277页

作者： marcos Sidney Brito Oliveira lincoln lima Corrê a liliane de Araújo Castro letícia Silva Brito marcos Tavares-dias Universidade Federal do Oeste do Pará -UFOPA Instituto de Ci&ecirc ncias e Tecnologia das &AACUTE guas (ICTA) Santar&eacute m Brazil Embrapa Amapá Macap&aacute Brazil

The present study investigated the fauna of metazoan parasites of a Geophagus proximus population from the lower Tapajós River, in the state of Pará, northern Brazil. A total of 137 monogeneans were collected from the gills of G. proximus, including Sciadicleithrum kritskyi, Sciadicleithrum paranaensis and Sciadicleithrum geophagi, while 119 Raphidascaris (Sprentascaris) lanfrediae nematodes and 28 metacercariaes of digenea undetermined were collected from the intestine. Hosts harboring four species of parasites were predominant. The parasites had an aggregated dispersion pattern. The present study represents the first record of S. geophagi parasitizing G. proximus, increasing the geographic distribution of these parasite species to the Tapajós River basin.

关键词： Helminths Parasites Freshwater Fish Tapajós River

An Application of Paraconsistent Annotated logic for Design Software Testing Strategies

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Journal of Software Engineering and Applications 2014年第5期7卷 371-386页

作者： marcos Ribeiro do Nascimento luiz Alberto Vieira dias Joao Inacio Da Silva Filho Brazillian Aeronautics Institute of Technology—ITA Sao Jose dos Campos Brazil Santa Cecília University—UNISANTA Santos Brazil

Nowadays, application model systems for decision-making based on non-classical logic such as Paraconsistent logic are used successfully in the treatment of uncertainties. The method presented in this paper is based on the fundamental concepts of Paraconsistent Annotated logic with annotation of 2 values (PAl2v). In this study, two algorithms based on PAl2v are presented gradually, to extract the effects of the contradiction in signals of information from a database of uncertain knowledge. The Paraconsistent Extractors Algorithms of Contradiction Effect-Para Extrctr is applied to filters of networks of analyses (PANets) of signal information, where uncertain and contradictory signals may be found. Software test case scenarios are subordinated to an application model of Paraconsistent decision-making, which provides an analysis using Paraconsistent logic in the treatment of uncertainties for design software testing strategies. This quality-quantity criterion to evaluate the software product quality is based on the characteristics of software testability analysis. The Para consistent reasoning application model system presented in this case study, reveals itself to be more efficient than the traditional methods because it has the potential to offer an appropriate treatment to different originally contradicting source information.

关键词： Paraconsistent logic Design Testing Strategies Software Testability Paraconsistent Decision Making Model

Optimization of the Electrospinning Conditions by Box-Behnken Design to Prepare Poly(Vinyl Alcohol)/Chitosan Crosslinked Nanofibers

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Journal of Materials Science and Chemical Engineering 2020年第4期8卷 13-31页

作者： Vinícius R. Viana Willian H. Ferreira Edwin G. Azero marcos l. dias Cristina T. Andrade Instituto de Macromoléculas Professora Eloisa Mano Universidade Federal do Rio de Janeiro Centro de Tecnologia Bloco J Rio de Janeiro Brazil Departmento de Ciências Naturais Universidade Federal do Estado do Rio de Janeiro Avenida Pasteur Rio de Janeiro Brazil

Electrospun poly(vinyl alcohol)/chitosan nanofibers had their solution and process parameters optimized using a Box-Behnken design and desirability function. Four factors (applied voltage, flow rate, distance tip-to-plate and amount of chitosan) were varied to produce electrospun mats with a low fiber diameter. An empirical model was developed for each response using response surface methodology (RSM), which revealed that flow rate had no significant influence on the assessed responses. With desirability function, the optimal conditions to produce the nanofibers were applied voltage of 13.1 kV, 30% chitosan concentration and distance tip-to-plate of 10 cm. The fiber diameter and standard deviation were 196.5 ± 28.3 nm, compared to the predicted values of 185.9 ± 26.8 nm. The desirability function allied with Box-Benhken design proved themselves important tools to predict process parameters for the development of nanofibers. The mats were crosslinked with glutaraldehyde for 24 h and 48 h and presented good water stability and enhanced mechanical properties.

关键词： Electrospinning Poly(Vinyl Alcohol) Chitosan Box-Behnken Design

Indolbutyric Acid and Time of the Year Influence on Rooting of Chrysanthemum Cuttings

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American Journal of Plant Sciences 2018年第3期9卷 507-516页

作者： Marina Romano Nogueira marcos Vieira Ferraz Amanda Kelly dias Bezerra Renata Bachin Mazzini-Guedes Carla Rafaele Xavier Costa lívia Caroline Praseres de Almeida Suzana Targanski Sajovic Pereira Kathia Fernandes lopes Pivetta Department of Plant Production Sao Paulo State University (Unesp) Jaboticabal Brazil Federal University of Paraná (UFPR) Jandaia do Sul Brazil

The objective of this study was to analyze the effect of the seasons and indol butyric acid (IBA), as well as the preparation of IBA solutions on rooting growth of “Fine Time” chrysanthemum cuttings. The first experiment was arranged in a 4 × 2 factorial scheme: IBA concentrations (0, 1000, 2000 and 3000 mg·l-1) during summer and winter with 4 replicates of two pots and six cuttings per pot. In the second experiment, the storage of IBA solution (1000 mg·l-1) at 15°C was studied with four replicates of 10 cuttings per plot in a period of four weeks. In the third experiment, dilution and supply of IBA (1000 mg·l-1 or 1000 mg·kg-1) were studied;there were eight treatments: (1) IBA mixed with industrial talc;(2) IBA diluted in 50% alcohol and oven dried at 30°C;(3) IBA diluted in 50% alcohol and oven dried at 70°C;(4) IBA diluted in NaOH and supplied via aqueous solution;(5) IBA diluted in acetone and supplied via aqueous solution;(6) IBA diluted in alcohol 92.8% and supplied via alcoholic solution;(7) IBA diluted in alcohol 50% and supplied via alcoholic solution;(8) IBA mixed and supplied via lanolin;with four replicates of 10 cuttings per plot. Twenty-one days after cutting implementation, the following variables were evaluated: rooting percentage, number, average length and root dry mass. Statistical analysis and time-of-year averages were compared using the Tukey test at 5%;polynomial regression for IBA concentration and preparation data. The means of dilution and delivery were compared by the Scott-Knott test. Treatment with IBA at a concentration of 3000 mg·kg-1 resulted in 90% rooting in the winter and 100% in the summer for all treatments. Results suggest the concentration of 2000 mg·l-1 in the summer and 2000 and 3000 mg·l-1 during the winter provided better quality for the root system. Cuttings treated with IBA diluted in 50% alcohol and oven dried at 30°C showed higher number, length and vigor of the roots.

关键词： Dendranthema grandiflora Cutting Asexual Propagation

Displacement of the non-reduction temporomandibular disk with limitation of opening. Story of a clinical case—Follow up five years

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Health 2014年第5期6卷 475-478页

作者： Gustavo Helder Vinholi Túlio marcos Kalife Coêlho Elizeu Insaurralde Anísio lima da Silva Gustavo Adolfo Pereira Terra luís Gustavo Nunes dias de Pinho Department of Restorative Dentistry and Prosthodontics Dental School Federal University of Mato Grosso do Sul Mato Grosso do Sul Brazil Postgraduate Program in Health and Development in the Midwest Region Medicine School Federal University of Mato Grosso do Sul Mato Grosso do Sul Brazil

Displacement of the non-reduction disk with limitation of opening (DDwlO) can be treatment of the non-surgical form. However, it required scientific and clinic knowledge of diagnostic area of the disorders temporomandibulares. This study was performed with the patient CN, 18 years, white, female, who went to the orofacial pain ambulatory with complaints of extreme pain on the right temporomandibular joint (TMJ) and limitation of maximum opening of 29 mm with shift to right, which she has been suffering for at least three years. After a criterion anamnese the diagnosis hypothesis found was a displacement of the non-reduction disk with limitation of opening. The treatment was based on infiltration in the right TMJ with anesthesic followed by mandibular manipulation. After the therapeutic conduct the patient presented clinical signals of normality with absence of trismus and mandibular movement without shift to right. The patient was followed up during five years not presenting return of the pathology.

关键词： Temporomandibular Disorders Displacement of the Disk Temporomandibular Joint