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search for production of dark fermion candidates in association with heavy neutral gauge boson decaying to dimuon in proton-proton collisions at√s=8 TeV using CMs open data

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Chinese Physics C 2024年第4期48卷 6-13页

作者： Y.Mahmoud H.Abdallah M.T.Hussein s.Elgammal Centre for theoretical physics The British University in EgyptEgypt Physics Department Faculty of ScienceCairo UniversityEgypt

In this study,we conducted a search for dark matter using a part of the data recorded by the CMs experiment during run-I of the LHC in 2012 with a center of mass energy of 8 TeV and an integrated luminosity of 11.6 fb−*** data were gathered from the CMs open *** matter,in the framework of the simplified model(mono-Z′),can be produced from proton-proton collisions in association with a new hypothetical gauge boson,Z′.Thus,the search was conducted in the dimuon plus large missing transverse momentum *** benchmark scenario of mono-Z′,which is known as light vector,was used for interpreting the CMs open *** evidence of dark matter was observed,and exclusion limits were set on the masses of dark matter and Z′at 95%confidence level.

关键词： dark matter large hadron collider CMs open data search for new physics dark fermion

AutoRhythmAI: A Hybrid Machine and Deep Learning Approach for Automated Diagnosis of Arrhythmias

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Computers, Materials & Continua 2024年第2期78卷 2137-2158页

作者： s.Jayanthi s.Prasanna Devi Department of Computer science and Engineering SRM Institute of Science and Technology-Vadapalani CampusChennaiTamil NaduIndia

In healthcare,the persistent challenge of arrhythmias,a leading cause of global mortality,has sparked extensive research into the automation of detection using machine learning(ML)***,traditional ML and AutoML approaches have revealed their limitations,notably regarding feature generalization and automation *** glaring research gap has motivated the development of AutoRhythmAI,an innovative solution that integrates both machine and deep learning to revolutionize the diagnosis of *** approach encompasses two distinct pipelines tailored for binary-class and multi-class arrhythmia detection,effectively bridging the gap between data preprocessing and model *** validate our system,we have rigorously tested AutoRhythmAI using a multimodal dataset,surpassing the accuracy achieved using a single dataset and underscoring the robustness of our *** the first pipeline,we employ signal filtering and ML algorithms for preprocessing,followed by data balancing and split for *** second pipeline is dedicated to feature extraction and classification,utilizing deep learning ***,we introduce the‘RRI-convoluted trans-former model’as a novel addition for binary-class *** ensemble-based approach then amalgamates all models,considering their respective weights,resulting in an optimal model *** our study,the VGGRes Model achieved impressive results in multi-class arrhythmia detection,with an accuracy of 97.39%and firm performance in precision(82.13%),recall(31.91%),and F1-score(82.61%).In the binary-class task,the proposed model achieved an outstanding accuracy of 96.60%.These results highlight the effectiveness of our approach in improving arrhythmia detection,with notably high accuracy and well-balanced performance metrics.

关键词： Automated machine learning neural networks deep learning arrhythmias

Machine learning-enhanced Monte Carlo and subset simulations for advanced risk assessment in transportation infrastructure

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Journal of Mountain science 2024年第2期21卷 690-717页

作者： Furquan AHMAD Pijush sAMUI s.s.MIsHRA Department of Civil Engineering National Institute of TechnologyPatna 800006India

The maintenance of safety and dependability in rail and road embankments is of utmost importance in order to facilitate the smooth operation of transportation *** study introduces a comprehensive methodology for soil slope stability evaluation,employing Monte Carlo simulation(MCs)and subset simulation(ss)with the"UPss 3.0 Add-in"in *** on an 11.693-meter embankment with a soil slope(inclination ratio of 2H:1V),the investigation considers earthquake coefficients(kh)and pore water pressure ratios(ru)following Indian zoning *** chance of slope failure showed a considerable increase as the Coefficient of Variation(COV),seismic coefficients(kh),and pore water pressure ratios(ru)experienced an *** ss approach showed exceptional efficacy in calculating odds of failure that are notably *** computational modeling,the study optimized the worst-case scenario using ANFIs-GA,ANFIs-GWO,ANFIs-PsO,and ANFIs-BBO *** ANFIs-PsO model exhibits exceptional accuracy(training R2=0.9011,RMsE=0.0549;testing R2=0.8968,RMsE=0.0615),emerging as the most *** study highlights the significance of conducting thorough risk assessments and offers practical insights into evaluating and improving the stability of soil slopes in transportation *** findings contribute to the enhancement of safety and reliability in real-world situations.

关键词： Monte Carlo simulation subset simulation Machine Learning seismic coefficient

肿瘤坏死因子α抑制剂治疗皮肤结节病的疗效及耐受性观察:来自法国的一项46例病例研究

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皮肤性病诊疗学杂志 2017年第4期24卷 300-300页

作者： Heidelberger V Ingen-Housz-Oro s Marquet A Mahevas M Bessis D Bouillet L Caux F Chapelon-Abric C Debarbieux s Delaporte E Duval-Modeste AB Fain O Joly P marchand-adam s Monfort JB Noёl N Passeron T Ruivard M sarrot-Reynauld F Verrot D Bouvry D Fardet L Chosidow O sève P Valeyre D 邓婕张锡宝 Department of Dermatology AP-HP Hôpital Henri Mondor Créteil France. Department of Dermatology AP-HP Hôpital Henri Mondor Créteil France2Department of Dermatology EA 7379 - EpiDermE Université Paris Est Créteil France. Department of Internal Medicine Hôpital de la Croix-Rousse Lyon France. Department of Internal Medicine APHP Hôpital Henri Mondor Créteil France. Department of Dermatology Hôpital Saint-Eloi Montpellier France. Department of Internal Medicine Centre hospitalier universitaire de Grenoble-Alpes Grenoble France. Department of Dermatology APHP Hôpital Avicenne Bobigny France. Department of Internal Medicine APHP Hôpital de la Pitié-Salpêtrière Paris France. Department of Dermatology Centre hospitalier Lyon-Sud Lyon France. Department of Dermatology Hôpital Claude Huriez Lille France. Department of Dermatology Hôpital Charles Nicolle Rouen France. Department of Internal Medicine APHP Hôpital Saint-Antoine Paris France. Department of Pneumology Hôpital Bretonneau Tours France. Department of Dermatology APHP Hôpital Tenon Paris France. Department of Internal Medicine APHP Hôpital Bicêtre Le Kremlin-Bicêtre France. Department of Dermatology Hôpital de l'Archet Nice France. Department of Internal Medicine Hôpital Estaing Clermont-Ferrand France. Department of Internal Medicine Hôpital Saint-Joseph Marseille France. Department of Pneumology APHP Hôpital Avicenne Bobigny France. Department of Dermatology AP-HP Hôpital Henri Mondor Créteil France2Department of Dermatology EA 7379 - EpiDermE Université Paris Est Créteil France20Department of Dermatology Université Paris Est UPEC Créteil France.

法国一项回顾性和前瞻性多中心研究对肿瘤坏死因子α抑制剂（anti-tumor necrosis factorα,TNFα抑制剂）治疗皮肤结节病的疗效和安全性做出了观察报告。自2004年1月~2016年1月期间,患者来自于多个教学医院、转诊中心、肺科、皮肤科和... 详细信息

法国一项回顾性和前瞻性多中心研究对肿瘤坏死因子α抑制剂（anti-tumor necrosis factorα,TNFα抑制剂）治疗皮肤结节病的疗效和安全性做出了观察报告。自2004年1月~2016年1月期间,患者来自于多个教学医院、转诊中心、肺科、皮肤科和内科,病理确诊为结节病,并接受抗-TNFα治疗。对治疗反应的评估使用肺外器官严重度评分（ePOsT,0为不受影响,6为非常严重）。

关键词：皮肤结节肿瘤坏死因子α 教学医院病例研究观察报告严重度结节病

Interatomic Interaction Models for Magnetic Materials:Recent Advances

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Chinese Physics Letters 2024年第6期41卷 54-66页

作者： Tatiana s.Kostiuchenko Alexander V.shapeev Ivan s.Novikov Emanuel Institute of Biochemical Physics RAs 4 Kosygin StreetMoscow119334Russian Federation Independent investigator

Atomistic modeling is a widely employed theoretical method of computational materials *** has found particular utility in the study of magnetic ***,magnetic empirical interatomic potentials or spinpolarized density functional theory(DFT)served as the primary models for describing interatomic interactions in atomistic simulations of magnetic ***,in recent years,a new class of interatomic potentials known as magnetic machine-learning interatomic potentials(magnetic MLIPs)has *** MLIPs combine the computational efficiency,in terms of CPU time,of empirical potentials with the accuracy of DFT *** this review,our focus lies on providing a comprehensive summary of the interatomic interaction models developed specifically for investigating magnetic *** also delve into the various problem classes to which these models can be ***,we offer insights into the future prospects of interatomic interaction model development for the exploration of magnetic materials.

关键词： materials interaction empirical

MgO-attached graphene nanosheet(MgO@GNs)reinforced magnesium matrix nanocomposite with superior mechanical,corrosion and biological performance

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International Journal of Minerals,Metallurgy and Materials 2024年第9期31卷 2062-2076页

作者： s.Abazari A.shamsipur H.R.Bakhsheshi-Rad M.s.soheilirad F.Khorashadizade s.s.Mirhosseini Department of Materials and Metallurgical Engineering Amirkabir University of TechnologyTehran ***Iran Iranian National standards Organization of Hormozgan HormozganIran Advanced Materials Research Center Department of Materials EngineeringNajafabad BranchIslamic Azad UniversityNajafabadIran Department of Materials and Metallurgical Engineering Iran University of Science and TechnologyTehranIran

Magnesium(Mg)alloys are gaining great consideration as body implant materials due to their high biodegradability and ***,they suffer from low corrosion resistance and antibacterial *** this research,semi-powder metallurgy followed by hot extrusion was utilized to produce the magnesium oxide@graphene nanosheets/magnesium(MgO@GNs/Mg)composite to improve mechanical,corrosion and cytocompatibility *** have revealed that the incorporation of MgO@GNs nanohybrids into Mg-based composite enhanced microhardness and compressive *** vitro,osteoblast cell culture tests show that using MgO@GNs nanohybrid fillers enhances osteoblast adhesion and apatite *** presence of MgO@GNs nanoparticles in the composites decreased the opening defects,micro-cracks and micro-pores of the composites thus preventing the penetration of the corrosive solution into the *** demonstrated that the MgO@GNs/Mg composite possesses excellent antibacterial properties because of the combination of the release of MgO and physical damage to bacterium membranes caused by the sharp edges of graphene nanosheets that can effectively damage the cell wall thereby facilitating penetration into the bacterial lipid ***,the MgO@GNs/Mg composite with high mechanical strength,antibacterial activity and corrosion resistance is considered to be a promising material for load-bearing implant applications.

关键词： metal matrix composites MgO@GNs nanohybrid strengthening mechanisms antibacterial activity biocompatibility

Direct microwave leaching conditions of rare earth elements in fluorescent wastes

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Journal of Rare Earths 2024年第6期42卷 1165-1174,I0007页

作者： A.Bilen B.Birol M.N.saridede s.s.Kaplan M.s.sonmez Department of Metallurgical and Materials Engineering Yildiz Technical UniversityIstanbulTurkey Department of Chemical Engineering and Materials science Stevens Institute of TechnologyNew JereyUSA Department of Metallurgical and Materials Engineering Istanbul Technical UniversityIstanbulTurkey

The luminescent phosphor powder in the fluorescent lamp constitutes 2%of the lamp’s *** can be mentioned that fluorescent wastes are a crucial raw material to produce rare earth *** the present study,microwave leaching process was conducted to dissolve rare earth elements yttrium(Y),europium(Eu),and remaining rare earth elements(REEs)present in the phosphor powder of the fluorescent *** the yields were *** the microwave leaching process,the effects of the temperature(80-160℃),acid type(hydrochloric acid(HCl),nitric acid(HNO_(3)),sulphuric acid(H_(2)sO_(4))),acid concentration(0.5-6 mol/L),solid to liquid ratio(0.1:10-0.5:10)and reaction time(5-90 min)parameters on leaching efficiencies of varying rare earth elements and calcium were *** highest yield was obtained in the direct microwave leaching of fluorescent waste with the experimental conditions of 6 mol/L HCl,160℃,0.1:10 solid-to-liquid ratio(s:L),and 90 *** energy calculations were made,and kinetic models of the reactions were obtained,and it is observed that Y and Eu dissolution is diffusion-controlled,on the other hand,lanthanum(La),cerium(Ce),and terbium(Tb)were examined to be chemical reaction ***,calcium(Ca)and gadolinium(Gd)seem coherent with the mixed ***,mathematical models of all experimental studies are created with the response surface Box-Behnken method and the correlation coefficients of all the models are over 90%.

关键词： Rare earth elements(REEs) Direct microwave leaching Fluorescent waste Kinetic models Response surface method

C-phycocyanin shows neuroprotective effect against rotenone-induced Parkinson’s disease in mice

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Asian Pacific Journal of Tropical Biomedicine 2024年第7期14卷 279-287页

作者： Hritik Rathod Ritu M.soni Jigna s.shah Department of Pharmacology Institute of Pharmacy Nirma UniversityAhmedabadGujaratIndia

Objective:To investigate the neuroprotective effect of C-phycocyanin in a mouse model of rotenone-induced Parkinson’s ***:C-phycocyanin(50 mg/kg,i.p.,daily)was administered to rotenone(30 mg/kg,p.o.,daily)treated mice for 28 *** studies(Y-maze,rotarod,round beam walk,and wire-hang tests)were carried out to assess neurobehavioral *** and malondialdehyde were determined in both serum and striatal *** proteins(AKT,AMPK,NF-κB,BDNF,and alpha-synuclein)in the striatum were estimated using *** analyses(hematoxylin and eosin stainning as well as Nissl staining)were carried out to assess structural abnormalities in the ***:C-phycocyanin significantly increased BDNF levels and decreased alpha-synuclein *** also slightly upregulated AMPK and AKT levels without significant difference compared with the rotenone ***,rotenone-induced elevated oxidative stress and structural abnormalities in the striatum were markedly mitigated by ***:C-phycocyanin might have potential neuroprotective effects against Parkinson’s *** studies are warranted to verify its efficacy and to understand the molecular mechanisms behind the neuroprotective effects of C-phycocyanin in Parkinson’s disease.

关键词： Parkinson’s disease C-phycocyanin Alphasynuclein BDNF Oxidative stress Rotenone

Low T3 vs low T3T4 euthyroid sick syndrome in septic shock patients:A prospective observational cohort study

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World Journal of Critical Care Medicine 2024年第3期13卷 53-62页

作者： Mirza Kovacevic Visnja Nesek-adam semir Klokic Ekrema Mujaric Department of Anesthesiology Resuscitation and Intensive CareCantonal HospitalZenica 72000Bosnia and Herzegovina Department of Anesthesiology Resuscitation and Intensive CareClinical Hospital Sveti DuhZagreb 10000Croatia Gruppenpraxis General Practitioner's OfficeLaufen 4242Switzerland Department of Internal Diseases Cantonal HospitalZenica 72000Bosnia and Herzegovina

BACKGROUND Both phases of euthyroid sick syndrome(Ess)are associated with worse prognosis in septic shock *** there are still no indications for supplementation therapy,there is no evidence that both phases(initial and prolonged)are adaptive or that only prolonged is maladaptive and requires *** To analyze clinical,hemodynamic and laboratory differences in two groups of septic shock patients with *** A total of 47 septic shock patients with Ess were divided according to values of their thyroid hormones into low T3 and low T3T4 *** analysis included demographic data,mortality scores,intensive care unit stay,mechanical ventilation length and 28-day survival and laboratory with *** The simplified Acute Physiology score II score(P=0.029),dobutamine(P=0.003)and epinephrine requirement(P=0.000)and the incidence of renal failure and multiple organ failure(MOF)(P=0.000)were significantly higher for the low ***(P=0.047),neutrophilia(P=0.038),lymphopenia(P=0.013)and lactatemia(P=0.013)were more pronounced on T2 for the low T3T4 group compared to the low T3 *** blood pressure at T0(P=0.017)and T1(P=0.007),as well as mean arterial pressure at T0(P=0.037)and T2(P=0.033)was higher for the low T3 *** The low T3T4 population is associated with higher frequency of renal insufficiency and MOF,with worse laboratory and hemodynamic *** findings suggest potentially maladaptive changes in the chronic phase of septic shock.

关键词： septic shock Euthyroid sick syndrome Low T3 Low T3T4 Intensive care unit