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World Journal of Gastroenterology 2017年第22期23卷 4132-4134页

作者： Lucia Ameghino Malco Damian Rossi Daniel Cerquetti marcelo Merello Movement Disorders Section Neuroscience Department Raul Carrea Institute for Neurological Research

Neurological features in celiac disease(CD) are not rare(5%-36%), but tremor is scarcely described. Subjects with CD and healthy controls completed an online survey using WHIGET tremor rating scale. One thousand five hundred and twelve subjects completed the survey, finally 674 CD patients and 290 healthy subjects were included. A higher prevalence of tremor in CD patients was observed in comparison to controls(28% vs 14%, P < 0.001). Frequency of family history of tremor in CD patients with and without tremor was 25% and 20%(P = 0.2), while in the control group it was 41% and 10%(P < 0.001). Controls with tremor showed a higher frequency of family history of tremor when compared to CD patients with tremor(41.5% vs 24.6%, P = 0.03). The results suggested that tremor in CD might be more frequent and possibly related to the disease itself and not due to associated essential tremor.

关键词： Tremor Celiac disease Gluten Gluten-free diet Movement disorders

Effects of Tectonic Setting and Hydraulic Properties on Silent Large-Scale Landslides:A Case Study of the Zhaobishan Landslide,China

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International Journal of Disaster Risk Science 2023年第4期14卷 600-617页

作者： Shufeng Tian Guisheng Hu Ningsheng Chen Mahfuzur Rahman Huayong Ni marcelo Somos-Valenzuela Key Lab of Mountain Hazards and Surface Processes Institute of Mountain Hazards and Environment Chinese Academy of Sciences University of Chinese Academy of Sciences Academy of Plateau Science and Sustainability Kathmandu Center for Research and Education Chinese Academy of Sciences-Tribhuvan University Department of Civil Engineering International University of Business Agriculture and Technology(IUBAT) Department of Civil Engineering Kunsan National University Institute of Exploration Technology China Geological Survey Department of Forest Sciences Faculty of Agriculture and Environmental SciencesUniversidad de La Frontera

Unlike strong earthquake-triggered or heavy rainfall-triggered landslides,silent large-scale landslides(SLL) occur without significant triggering factors and cause unexpected significant disaster risks and mass *** the initiation mechanism of SLLs is crucial for risk *** this study,the mechanism of the Zhaobishan SLL was investigated,and the SLL was jointly controlled by weak-soil(fractured rock mass) and strong-water(abundant water replenishment)conditions under the impact of active tectonism and complex hydraulic *** tectonic uplift,high fault density,and historical earthquakes led to weak-soil conditions conducive to the Zhaobishan *** combined effect of unique lithology,antiform,and cultivated land contributed to the water replenishment characteristics of extensive runoff confluence(3.16 times that of the landslide body) and supported long-distance groundwater replenishment,thereby forming strongwater conditions for the *** amplified seepage amount caused the strength of the soil mass on the sliding surface to decrease to 0.4 times its initial strength,eventually triggering the Zhaobishan SLL,which occurred 4.6 days after the peak ***,the landslide deposits have accumulated on the semi-diagenetic clay rock,thereby controlling the subsequent recurring debris flows in the Lengzi *** reduce disaster risk of SLL in vulnerable mountainous regions,the water confluence area behind the main scarp of the landslides and the hysteresis characteristics between landslides and peak rainfall should be further considered,and recurring debris flows following massive landslides also should be focused.

关键词： Debris flow Hydraulic properties Risk reduction Runoff amplification Silent large-scale landslides (SLL) Tectonic setting

Platelet rich plasma(PRP)induces autophagy in osteoblast precursor 3T3-L1

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BIOCELL 2018年第1期42卷 13-16页

作者： SERGIO ANDRES CARMINATI MARÍA CAROLINA BARBOSA CLAUDIO marcelo FADER Universidad Nacional de Cuyo Facultad de OdontologíaMendozaArgentina Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET).Instituto de Histología y Embriología(IHEM) Facultad de Ciencias MédicasUniversidad Nacional de CuyoMendozaArgentina

Autophagy is an essential cellular homeostatic mechanism by which intracellular components are delivered into the lysosomes for degradation and *** has been related with a diversity of pathological or physiological dentary processes such as bone remodeling,skeletal aging,osteoclastogenesis,osteoblastogenesis and different types of oral ***-rich plasma(PRP),isolated from autologous blood,is a plasma preparation containing a higher concentration of platelets which contains numerous different growth factors and cytokines that activate several cellular signaling *** purpose of this study is to investigate the effect of PRP on autophagy stimulation in both osteoblast precursor 3T3-L1 and non-related osteoblastic *** results showed that PRP can increase the number of autophagic structures in 3T3-L1 and HeLa(cervical cancer cells)***,we have determined by Western blot a rise in the lipidated form of the autophagic protein LC3(***3-II)upon PRP *** together,our results suggest that PRP is able to induce a strongly autophagy response in osteoblast precursor and,to a lesser extent,in non-related osteoblastic cells,suggesting that PRP could be a potential therapeutic tool for some autophagy-related diseases associated with bone homeostasis.

关键词： Autophagy 3T3-L1 Platelet rich plasma Odontology

Conformal and continuous deposition of bifunctional cobalt phosphide layers on p-silicon nanowire arrays for improved solar hydrogen evolution

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Nano Research 2018年第9期11卷 4823-4835页

作者： Sitaramanjaneva Mouli Thalluri Jerome Borme Kang Yu Junyuan Xu Isilda amorim Joao Gaspar Liang Qiao Paulo Ferreira Pedro Alpuim Lifeng Liu International Iberian Nanotechnology Laboratory (INL) Av. Mestre. Jose Veiga Braga 4715-330 Portugal Materials Science and Engineering Program University of Texas at Austin Austin TX78712 USA Deportment of Chemistry State Key Laboratory of Molecular Engineering of Polymers and Institute of Biomedical Sciences Fudon University Shanghai 200433 China Mechanical Engineering Department and IDMEC Instituto Superior Tdcnico University of Lisbon Av. Rovisco Pais Lisboa 1049-007 Portugal Center of Physics University of Minho Braga 4710-057 Portugal

Vertically aligned p-silicon nanowire （SiNW） arrays have been extensively investigated in recent years as promising photocathodes for solar-driven hydrogen evolution. However, the fabrication of SiNW photocathodes with both high photoelectrocatalytic activity and long-term operational stability using a simple and affordable approach is a challenging task. Herein, we report conformal and continuous deposition of a di-cobalt phosphide （C02P） layer on lithography- patterned highly ordered SiNW arrays via a cost-effective drop-casting method followed by a low-temperature phosphorization treatment. The as-deposited C02P layer consists of crystalline nanoparticles and has an intimate contact with SiNWs, forming a well-defined SiNW@Co2P core/shell nanostructure. The conformal and continuous Co2P layer functions as a highly efficient catalyst capable of substantially improving the photoelectrocatalytic activity for the hydrogen evolution reaction （HER） and effectively passivates the SiNWs to protect them from photo-oxidation, thus prolonging the lifetime of the electrode. As a consequence, the SiNW@Co2P photocathode with an optimized C02P layer thickness exhibits a high photocurrent density of -21.9 mA·cm^-2 at 0 V versus reversible hydrogen electrode and excellent operational stability up to 20 h for solar-driven hydrogen evolution, outperforming many nanostructured silicon photocathodes reported in the literature. The combination of passivation and catalytic functions in a single continuous layer represents a promising strategy for designing high-performance semiconductor photoelectrodes for use in solar-driven water splitting, which may simplify fabrication procedures and potentially reduce production costs.

关键词： solar-driven hydrogenevolution silicon nanowire cobalt phosphide photoelectrochemical water splitting drop-casting

Ontogenetic niche specialization of the spider crab Libinia ferreirae associated with the medusa Lychnorhiza lucerna

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Current Zoology 2022年第5期68卷 549-559页

作者： Geslaine Rafaela Lemos Gonçalves Milena Regina Wolf Mariana Antunes Felipe Wanderley amorim Maria Lucia Negreiros-Fransozo Antonio Leão Castilho Group of Studies on Crustacean Biology Ecology and Culture-NEBECCBiosciences InstituteSão Paulo State UniversityBotucatuSP 18618-689Brazil and Laboratory of Pollination Ecology and Interactions-LEPI Biosciences InstituteSão Paulo State UniversityBotucatuSP 18618-689Brazil

Symbiotic relationships in marine environments are not fixed and can change throughout the animal’s *** study investigated the ontogeny of symbiosis of the spider crab Libinia ferreirae with the host medusa Lychnorhiza *** described the type of relationship,the temporal correlation among species,and food *** than 50%of the sampled crabs were symbionts,most in early life *** highest number of crabs found in a single medusa was *** was observed throughout most of the year but was more evident in warm *** crab has many benefits in this relationship with a *** is the use of food resources captured by the medusa,primarily *** the crab steals the medusa’s food,it is a kleptoparasitic *** is a niche partition between symbiont and the free-living crabs as they occupy different habitats and use nonoverlapping food *** research reported that symbiosis first developed during the crab’s last larval phase(megalopa)when crab and medusa are in the same *** of the crab’s behavior shows that symbiosis occurs when the crab can grab to the medusa when the host touches the sea *** crab also took advantage of water currents,releasing itself from the substrate and then drifting toward the *** symbiotic relationship that crabs have with the medusa provides then with a nursery,food resources,shelter,dispersion,and decreased competition with free-living adult crabs,all essential for the crab’s survival.

关键词： behavior development kleptoparasitism megalopa niche segregation

RANS feasibility study of using roughness to mimic transition strip effect on the crossflowseparation over a 6:1 prolate-spheroid

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Journal of Hydrodynamics 2019年第3期31卷 570-581页

作者： Mojtaba M. Amiri marcelo A. Vitola Sergio H. Sphaier, Paulo T. Esperanza Ocean Technology Laboratory (LabOceano-COPPE) Federal University of Rio de Janeiro Rio de Janeiro RJ 21941-907 Brazil

An axisymmetric body at incidence experiences the three-dimensional crossflow separation. This separation is attributed to the adverse circumferential pressure gradient. However, the separation pattern is also dependent upon the structure of the boundary layer. In this regard, utilization of transition strip devices in experiments on axisymmetric bodies may modify this structure, and consequently the crossflow separation pattern. The main objective of the present research is to mimic numerically the transition strip effect on the crossflow separation over a 6:1 prolate-spheroid up to a = 30° incidence and ReL = 4.2 x 10&. However, to avoid direct modeling of the strip, which would increase the computational cost, an attempt was made to add roughness over the body surface. To estimate the roughness that simulates closely the transition strip effect, three different roughness values were considered. The numerical model is based on RANS and a Reynolds stress turbulence model implemented in STARCCM+. The simulations have been evaluated based on the local and global variables and validated against the available experimental data. The results demonstrate the effectiveness of using a proper roughness value to mimic the transition strip effect. They also show the importance of modeling the transition strip effect, which is normally not taken into account, to capture the crossflow separation pattern.

关键词： Axisymmetric body crossflow separation transition strip device CFD RANS equations

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企业文化变革,从讲述新故事开始

企业家信息 2024年第1期 72-74页

作者：杰伊·巴尼马诺埃尔·阿莫林卡洛斯·胡里奥夏林(翻译) 犹他大学大卫·伊柯丽斯商学院 MXF Investments 不详

众所周知,战略和文化一致的公司,业绩会优于不一致的公司。因此,如果战略与文化不一致,企业文化就很可能需要进行调整知易行难。构成企业文化的价值观、信念和规范多为无形,并且弥漫整个组织,很难控制和影响。同时人们对待组织变革往往... 详细信息

众所周知,战略和文化一致的公司,业绩会优于不一致的公司。因此,如果战略与文化不一致,企业文化就很可能需要进行调整知易行难。构成企业文化的价值观、信念和规范多为无形,并且弥漫整个组织,很难控制和影响。同时人们对待组织变革往往持抵制态度。

关键词：知易行难企业文化变革组织变革价值观

Inter Seasonality of the Energy Fluxes in Brazilian Savana—Mato Grosso—Brazil

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Atmospheric and Climate Sciences 2014年第2期4卷 219-230页

作者： Leone Francisco amorim Curado José de Souza Nogueira Luciana Sanches Thiago Rangel Rodrigues Francisco de Almeida Lobo marcelo Sacardi Bíudes Federal University of Mato Grosso Cuiabá Brazil

Dynamics of flows of matter and energy these biomes are relevant to understanding of environmental processes that govern the biosphere-atmosphere interactions and between ecosystems. This study analyzed inter season and season of energy fluxes in Brazilian Savana through Bowen Ration Method. Results show differences in patterns LE in all season, LE predominant in wet while H in dry. This inversion in patterns of predominant components of the energy balance in wet and dry season because in wet season increase water content in soil and atmosphere due precipitation in this season providing more lost energy for atmosphere in shape LE through soil evaporation and plant transpiration, this results in LE and H in all season of the Brazilian Savana show higher variation in dynamics energy fluxes between surface and atmosphere, as well as energy partition in this biome. Statistics analyses presents than many climate variables influences LE and H in each season indicating complexity in this fluxes. More study is necessary to higher understand patterns energies fluxes in Brazilian Savana.

关键词： Patterns Energies LE H Bowen Ration

Effects of submergence in water on seed germination and vigor of the Copaifera lucens(Fabaceae) seedlings

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Journal of Forestry Research 2014年第4期25卷 903-908页

作者： Daniela Baldez Vidal Isis Leite Andrade Eusinia Louzada Pereira Andrade marcelo Schramm Mielke Department of Agricultural and Environmental Sciences State University of Santa Cruz BR 415 km 16 Ilhéus 45662-300 Bahia Brazil Department of Biological Sciences State University of Santa Cruz BR 415 km 16 Ilhéus 45662-300 Bahia Brazil

We analyzed the tolerance of Copaifera lucens seeds to sub- mersion in water to assess the use of this species for direct seeding in riparian forest restoration programs. Seeds were submerged in water for 2, 4, 8, 16 and 32 days or not submerged （control = 0 days of submer- gence）. For the control and at the end of each period of submersion, germination and seedling vigor tests were carried out. For germination tests, seeds were sown in plastic pots containing sand and kept in labora- tory conditions. The percentage of seed germination, the germination rate and the average germination time were analyzed. For seedlings, total biomass, leaf area, leaf mass per area and leaf area ratio were analyzed. Submersion time drastically affected the dissolved oxygen content and seed germination. Between 4 and 8 days of submersion there was a de- crease from 83.8% to 15.6% in the germination percentage. No seed germination occurred after 16 days of submersion. Although there was a significant decrease in the percentage of seed germination between 4 and 8 days of submersion, seedling vigor was not affected. Seeds of this species were partially tolerant to submersion in water, suggesting that C. lucens is a promising species for direct seeding in riparian forest restora- tion projects.

关键词： Copaiba Brazilian Atlantic Forest forest restoration germi-nation vigor