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Application of antibody-conjugated small intestine submucosa to capture urine-derived stem cells for bladder repair in a rabbit model

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Bioactive Materials 2022年第8期7卷 443-455页

作者： Yu-Ting Song Yan-Qing Li mao-xuan tian Jun-Gen Hu Xiu-Ru Zhang Peng-Cheng Liu Xiu-Zhen Zhang Qing-Yi Zhang Li Zhou Long-Mei Zhao Jesse Li-Ling Hui-Qi Xie Laboratory of Stem Cell and Tissue Engineering Orthopedic Research InstituteMed-X Center for MaterialsState Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengduSichuan610041China Department of Aesthetic Surgery The People’s Hospital of PengzhouChengduSichuan611930China Surgery of Spine and Spinal Cord Henan Provincial People’s HospitalZhengzhouHenan450000China Department of Burn and Plastic Surgery West China HospitalSichuan UniversityChengduSichuan610041China Research Core Facility of West China Hospital Sichuan UniversityChengduSichuan610041China Department of Medical Genetics and Prenatal Diagnosis West China Second HospitalSichuan UniversityChengduSichuan610041China

The need for bladder reconstruction and side effects of cystoplasty have spawned the demand for the development of alternative material *** such as submucosa of small intestine(SIS)have been widely used as patches for bladder repair,but the outcomes are not fully *** capture stem cells in situ has been considered as a promising strategy to speed up the process of re-cellularization and *** this study,we have developed an anti-CD29 antibody-conjugated SIS scaffold(AC-SIS)which is capable of specifically capturing urine-derived stem cells(USCs)in situ for tissue repair and *** scaffold has exhibited effective capture capacity and sound *** vivo experiment proved that the AC-SIS scaffold could promote rapid endothelium healing and smooth muscle *** endogenous stem cell capturing scaffolds has thereby provided a new revenue for developing effective and safer bladder patches.

关键词： Regenerative medicine Bladder tissue engineering Scaffold Antibody-conjugated

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Smart Gas Sensors: Recent Developments and Future Prospective

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NANO-MICRO LETTERS 2025年第1期17卷 1-32页

作者： Zong, Boyang Wu, Shufang Yang, Yuehong Li, Qiuju Tao, tian mao, Shun Tongji Univ Biomed Multidisciplinary Innovat Res Inst Coll Environm Sci & Engn Shanghai East HospState Key Lab Pollut Control & 1239 Siping Rd Shanghai 200092 Peoples R China Shanghai Inst Pollut Control & Ecol Secur Shanghai 200092 Peoples R China Southern Med Univ Zhujiang Hosp Microbiome Med Ctr Dept Lab Med Guangzhou 510280 Peoples R China

Recent developments of advanced electronic and optoelectronic gas sensors are *** array with artificial intelligence algorithms and smart gas sensors in "Internet of Things" paradigm are *** of smart gas sensors in environmental monitoring, medical and healthcare applications, food quality control, and public safety are described. Gas sensor is an indispensable part of modern society with wide applications in environmental monitoring, healthcare, food industry, public safety, etc. With the development of sensor technology, wireless communication, smart monitoring terminal, cloud storage/computing technology, and artificial intelligence, smart gas sensors represent the future of gas sensing due to their merits of real-time multifunctional monitoring, early warning function, and intelligent and automated feature. Various electronic and optoelectronic gas sensors have been developed for high-performance smart gas analysis. With the development of smart terminals and the maturity of integrated technology, flexible and wearable gas sensors play an increasing role in gas analysis. This review highlights recent advances of smart gas sensors in diverse applications. The structural components and fundamental principles of electronic and optoelectronic gas sensors are described, and flexible and wearable gas sensor devices are highlighted. Moreover, sensor array with artificial intelligence algorithms and smart gas sensors in "Internet of Things" paradigm are introduced. Finally, the challenges and perspectives of smart gas sensors are discussed regarding the future need of gas sensors for smart city and healthy living.

关键词： Smart gas sensor Electronic sensor Optoelectronic sensor Flexible and wearable sensor Artificial intelligence

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Review of precipitation strengthening in ultrahigh-strength martensitic steel

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 256-269页

作者： Zhihao tian Chunlei Shang Chaolei Zhang Xiaoye Zhou Honghui Wu Shuize Wang Guilin Wu Junheng Gao Jiaming Zhu Xinping mao Institute for Carbon Neutrality University of Science and Technology BeijingBeijing 100083China Institute of Steel Sustainable Technology Liaoning Academy of MaterialsShenyang 110004China Department of Materials Science and Engineering Shenzhen MSU-BIT UniversityShenzhen 518172China Institute of Materials Intelligent Technology Liaoning Academy of MaterialsShenyang 110004China School of Civil Engineering Shandong UniversityJinan 250061China

Martensite is an important microstructure in ultrahigh-strength steels,and enhancing the strength of martensitic steels often involves the introduction of precipitated phases within the martensitic *** considerable research efforts devoted to this area,a systematic summary of these advancements is *** review focuses on the precipitates prevalent in ultrahigh-strength martensitic steel,primarily carbides(e.g.,MC,M_(2)C,and M_(3)C)and intermetallic compounds(e.g.,Ni Al,Ni_(3)X,and Fe_(2)Mo).The precipitation-strengthening effect of these precipitates on ultrahigh-strength martensitic steel is discussed from the aspects of heat treatment processes,microstructure of precipitate-strengthened martensite matrix,and mechanical ***,a perspective on the development of precipitation-strengthened martensitic steel is presented to contribute to the advancement of ultrahigh-strength martensitic *** review highlights significant findings,ongoing challenges,and opportunities in the development of ultrahigh-strength martensitic steel.

关键词： ultrahigh-strength martensitic steel precipitation strengthening mechanical property carbide intermetallic compound

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“Slope-adsorption & plateau-pore filling” mechanism unlocking the potential of hard carbon anodes for “fast-charging & large-sized”batteries

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Science China Materials 2025年第1期 309-311页

作者： tian Liang Xiaoming Zhu Hubei Key Laboratory of Radiation Chemistry and Functional Materials School of Nuclear Technology and Chemistry & Biology Hubei University of Science and Technology

To date, there has been no report on fast-charging and Ahlevel sodium-ion batteries (SIBs) by utilizing thick hard carbon anodes that demonstrate prolonged cycling life and high areal capacity at high rates. Further, the relationship among the complex structure of hard carbon, storage mechanism, and fastcharging performance in alkali-metal ion batteries has been a subject of ongoing debate [1,2].

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Research status and prospects of the fractal analysis of metal material surfaces and interfaces

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 20-38页

作者： Qinjin Dai Xuefeng Liu Xin Ma Shaojie tian Qinghe Cui Beijing Advanced Innovation Center for Materials Genome Engineering University of Science and Technology BeijingBeijing 100083China Beijing Laboratory of Metallic Materials and Processing for Modern Transportation University of Science and Technology BeijingBeijing 100083China Laboratory for Advanced Materials Processing of Ministry of Education University of Science and Technology BeijingBeijing 100083China School of Mechanical and Electrical Engineering Xinjiang Institute of EngineeringUrumqi 830023China

As a mathematical analysis method,fractal analysis can be used to quantitatively describe irregular shapes with self-similar or self-affine *** analysis has been used to characterize the shapes of metal materials at various scales and *** methods make it difficult to quantitatively describe the relationship between the regular characteristics and properties of metal material surfaces and ***,fractal analysis can be used to quantitatively describe the shape characteristics of metal materials and to establish the quantitative relationships between the shape characteristics and various properties of metal *** the perspective of two-dimensional planes and three-dimensional curved surfaces,this paper reviews the current research status of the fractal analysis of metal precipitate interfaces,metal grain boundary interfaces,metal-deposited film surfaces,metal fracture surfaces,metal machined surfaces,and metal wear *** relationship between the fractal dimensions and properties of metal material surfaces and interfaces is *** from three perspectives of fractal analysis,namely,research scope,image acquisition methods,and calculation methods,this paper identifies the direction of research on fractal analysis of metal material surfaces and interfaces that need to be *** is believed that revealing the deep influence mechanism between the fractal dimensions and properties of metal material surfaces and interfaces will be the key research direction of the fractal analysis of metal materials in the future.

关键词： metal material surfaces and interfaces fractal analysis fractal dimension homogeneity

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Cu^(2+)污染下农作物叶片特征光谱探究

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光谱学与光谱分析 2025年第1期45卷 264-271页

作者：张超吴轩杨可明齐钒宇夏天中国地质调查局发展研究中心北京100037 中国地质大学(北京)地球科学与资源学院北京100083 全国地质资料馆北京100037 中国矿业大学(北京)地球科学与测绘工程学院北京100083 中国资源卫星应用中心北京100094

为探究重金属胁迫下农作物污染响应的敏感叶型及谱段,设计了室外温室环境下的不同铜胁迫梯度玉米花盆试验。以玉米叶片为探究对象,利用仪器测定了出穂期玉米叶片的高光谱反射率数据以及叶片中重金属含量数据,为研究提供了基础数据。从... 详细信息

为探究重金属胁迫下农作物污染响应的敏感叶型及谱段,设计了室外温室环境下的不同铜胁迫梯度玉米花盆试验。以玉米叶片为探究对象,利用仪器测定了出穂期玉米叶片的高光谱反射率数据以及叶片中重金属含量数据,为研究提供了基础数据。从频率域角度,结合时频分析的方法设计了叶片光谱探测法(LSDM),获得了重金属铜胁迫下敏感叶型及谱段,为农作物重金属监测提供技术支撑。根据玉米的生长过程,从老叶(O)、中叶(M)、新叶(N)光谱350~1300 nm的全谱段和子谱段角度进行探究。(1)对铜胁迫下玉米叶片的高光谱反射率数据进行双微分(SOD)和包络线移除(CR),转换到频率域上,结合时频分析的方法进行Daubechies小波6层分解。(2)根据信号异常点、小波高值点和SODCR曲线高值点,定义玉米叶片的光谱异常参数(SAP)。异常变化反射率ACR(异常反射率与其后一个相邻波段反射率差值的绝对值);异常小波系数AWC(异常小波系数与其后一个相邻波段小波系数差值的绝对值);异常SODCR值ASV(异常点SODCR值与其后一个相邻波段SODCR值差值的绝对值)。通过光谱异常参数与玉米叶片重金属含量的相关关系,探究对铜污染响应敏感的叶型及谱段。结果表明,叶片光谱探测法LSDM能高效地对玉米叶片弱信息进行增强,并准确定位出重金属铜胁迫引起的光谱异常谱段位置,异常变化范围集中在350~800 nm内;光谱异常参数能定量地衡量玉米叶片在重金属铜胁迫下的光谱异常;在不同铜胁迫梯度下,玉米新叶(N)为敏感叶型,敏感谱段为蓝边、绿峰、黄边、红谷。该研究有望为其他谷类农作物及其冠层尺度重金属监测提供技术支撑。

关键词：重金属胁迫玉米叶片高光谱敏感叶型敏感谱段

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Nanocarrier-mediated siRNA delivery:a new approach for the treatment of traumatic brain injury-related Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2538-2555页

作者： Jie Jin Huajing Zhang Qianying Lu Linqiang tian Sanqiao Yao Feng Lai Yangfan Liang Chuanchuan Liu Yujia Lu Sijia tian Yanmei Zhao Wenjie Ren Institute of Disaster and Emergency Medicine Tianjin UniversityTianjinChina Key Laboratory for Disaster Medicine Technology TianjinChina Henan Medical Key Laboratory for Research of Trauma and Orthopedics The Third Affiliated Hospital of Xinxiang Medical UniversityXinxiangHenan ProvinceChina Clinical Medical Center of Tissue Engineering and Regeneration Xinxiang Medical UniversityXinxiangHenan ProvinceChina Institutes of Health Central Plain Xinxiang Medical UniversityXinxiangHenan ProvinceChina School of Public Health Xinxiang Medical UniversityXinxiangHenan ProvinceChina

Traumatic brain injury and Alzheimer's disease share pathological similarities,including neuronal loss,amyloid-βdeposition,tau hyperphosphorylation,blood-brain barrier dysfunction,neuroinflammation,and cognitive ***,traumatic brain injury can exacerbate Alzheimer's disease-like pathologies,potentially leading to the development of Alzheimer's *** offer a potential solution by facilitating the delive ry of small interfering RNAs across the blood-brain barrier for the targeted silencing of key pathological genes implicated in traumatic brain injury and Alzheimer's disease.U nlike traditional approaches to neuro regeneration,this is a molecula r-targeted strategy,thus avoiding non-specific drug *** review focuses on the use of nanocarrier systems for the efficient and precise delive ry of siRNAs,discussing the advantages,challenges,and future *** principle,siRNAs have the potential to target all genes and non-targetable protein s,holding significant promise for treating various *** the various therapeutic approaches currently available for neurological diseases,siRNA gene silencing can precisely"turn off"the expression of any gene at the genetic level,thus radically inhibiting disease progression;however,a significant challenge lies in delivering siRNAs across the blood-brain *** have received increasing attention as an innovative drug delive ry tool fo r the treatment of brain *** are considered a potential therapeutic strategy with the advantages of being able to cross the blood-brain barrier,targeted drug delivery,enhanced drug stability,and multifunctional *** use of nanoparticles to deliver specific modified siRNAs to the injured brain is gradually being recognized as a feasible and effective *** this strategy is still in the preclinical exploration stage,it is expected to achieve clinical translation in the future,creating a new field of molecular tar

关键词： blood-brain barrier cognitive dysfunction exosomes gene silencing immunotherapy inorganic nanomaterials liposome nanoparticles neuroinflammation polymer nanoparticles stem cells

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Highly coupled off-resonance lattice design in diffraction-limited light sources

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Nuclear Science and Techniques 2024年第9期35卷 92-102页

作者： Yi-Hao Gong Shun-Qiang tian Xin-Zhong Liu Shou-Zhi xuan Li-Yuan Tan Ling-Long mao Shanghai Advanced Research Institute Chinese Academy of Sciences Shanghai 201204 ShanghaiChina Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai 201800 ShanghaiChina University of Chinese Academy of Sciences 100049 BeijingChina

The round-beam operation presents many benefits for scientific experiments regarding synchrotron radiation and the weak-ening influences of intra-beam scattering in diffraction-limited synchrotron light sources.A round-beam generation method based on the global setting of skew quadrupoles and the application of a non-dominated sorting genetic algorithm was pro-posed in this *** schemes,including large-emittance coupling introduced via betatron coupling and vertical disper-sion,were explored in a candidate lattice for an upgrade-proposal of the Shanghai synchrotron radiation *** variations with lattice imperfections and their influence on the beam dynamics of beam optic distortions were *** results demonstrated that a precise coupling control ranging from 10 to 100%was achieved under low optical distortion,whereas full-coupling generation and its robustness were achieved by our proposed method by adjusting the skew quadrupole components located in the dispersion-free *** Touschek lifetime increased by a factor of 2–2.5.

关键词： Diffraction-limited storage ring(DLSR) Shanghai synchrotron radiation facility upgrade(SSRF-U) Round beam Off-resonance coupling

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A Novel Self-Supervised Learning Network for Binocular Disparity Estimation

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 209-229页

作者： Jiawei tian Yu Zhou Xiaobing Chen Salman A.AlQahtani Hongrong Chen Bo Yang Siyu Lu Wenfeng Zheng Department of Computer Science and Engineering Major in Bio Artificial IntelligenceHanyang UniversityAnsan-si15577Republic of Korea School of Electrical and Computer Engineering Louisiana State UniversityBaton RougeLA 70803USA Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityRiyadh11574Saudi Arabia School of Automation University of Electronic Science and Technology of ChinaChengdu610054China

Two-dimensional endoscopic images are susceptible to interferences such as specular reflections and monotonous texture illumination,hindering accurate three-dimensional lesion reconstruction by surgical *** study proposes a novel end-to-end disparity estimation model to address these *** approach combines a Pseudo-Siamese neural network architecture with pyramid dilated convolutions,integrating multi-scale image information to enhance robustness against lighting *** study introduces a Pseudo-Siamese structure-based disparity regression model that simplifies left-right image comparison,improving accuracy and *** model was evaluated using a dataset of stereo endoscopic videos captured by the Da Vinci surgical robot,comprising simulated silicone heart sequences and real heart video *** results demonstrate significant improvement in the network’s resistance to lighting interference without substantially increasing ***,the model exhibited faster convergence during training,contributing to overall performance *** study advances endoscopic image processing accuracy and has potential implications for surgical robot applications in complex environments.

关键词： Parallax estimation parallax regression model self-supervised learning Pseudo-Siamese neural network pyramid dilated convolution binocular disparity estimation

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First Passage Density of Brownian Motion with Two-sided Piecewise Linear Boundaries

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1505-1520页

作者： Zhen YU mao Zai tian Center for Applied Statistics School of StatisticsRenmin University of ChinaBeijing 100872P.R.China School of Mathematics and Data Science Changji UniversityChangji 831100P.R.China

The first passage time has many applications in fields like finance,econometrics,statistics,and ***,explicit formulas for the first passage density have only been obtained for a few *** paper derives an explicit formula for the first passage density of Brownian motion with twosided piecewise continuous boundaries which may have some points of *** are used to obtain a simplified formula for estimating the first passage ***,the results are also generalized to the case of two-sided general nonlinear *** can be easily carried out with Monte Carlo method and it is demonstrated for several typical two-sided boundaries that the proposed approximation method offers a highly accurate approximation of first passage density.

关键词： Boundary non-crossing probability first density passage density two-sided piecewise continuous boundaries Brownian motion

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