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数字化与可视化柔性机加单元管控系统

兵工自动化 2024年第1期43卷 6-13,18页

作者：孙科星眭阳天梁海洋谢敏赵智聪徐曼菲中国兵器装备集团自动化研究所有限公司智能制造事业部四川绵阳621000

针对目前多数机加车间存在的信息交互能力不足、生产管理效率低下、可视化程度低等问题,基于OPC UA数据交互技术与虚拟监控技术,设计并实现以4台机床为加工核心的自动化和柔性化数控机加单元管控系统。使用Unity3D软件搭建单元实时监控... 详细信息

针对目前多数机加车间存在的信息交互能力不足、生产管理效率低下、可视化程度低等问题,基于OPC UA数据交互技术与虚拟监控技术,设计并实现以4台机床为加工核心的自动化和柔性化数控机加单元管控系统。使用Unity3D软件搭建单元实时监控模块,借助通信技术与柔性调度技术,以提升机加单元数字化与自动化能力。结果表明:该系统能提高机加单元管理与调度能力,解决信息展示与交互程度低的问题,促进车间加工效率的提升。

关键词：数据采集虚拟监控柔性机加单元数字化

Rapid analysis of spatial distribution of PVPP and hardness of Yinhuang dispersible tablets by NIR-CI

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Journal of Innovative Optical Health Sciences 2016年第2期9卷 1-7页

作者： Yifei Wang Zhisheng Wu Zhaoyi Wang manfei xu Xinyuan Shi Yanjiang Qiao Beijing University of Chinese Medicine P.R.China Key Laboratory of TCM-information Engineering of State Administration of TCM Beijing 100102 P.R.China

The present study aimed at investigating the relationship between tablet hardness and homogeneity of different Yinhuang dispersible tablets by near-infrared chemical imaging(NIR-CI)*** regularity of best hardness was founded between tablet hardness and the spatial distribution uniformity of Yinhuang dispersible *** ingredients homogeneity of Yinhuang dispersible tablets could be spatially determined using basic analysis of correlation between analysis(BACRA)method and binary *** different hardnesses of Yinhuang dispersible tablets were ***,the regularity between tablet hardness and the spatial distribution uniformity of Yinhuang dispersible tablets was illuminated by quantifying the agglomerate of polyvinyl poly pyrrolidone(PVPP).The result demonstrated that the distribution of PVPP was unstable when the hardness was too large or too small,while the agglomerate of PVPP was smaller and more stable when the best tablet hardness was 75 *** paper provided a novel methodology for selecting the best hardness in the tabletting process of Chinese Medicine Tablet.

关键词： Near-infrared chemical imaging Yinhuang dispersible tablets PVPP tablet hardness

Near-infrared chemical imaging for quantitative analysis of chlorpheniramine maleate and distribution homogeneity assessment in pharmaceutical formulations

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Journal of Innovative Optical Health Sciences 2016年第6期9卷 12-20页

作者： manfei xu Luwei Zhou Qiao Zhang Zhisheng Wu Xinyuan Shi Yanjiang Qiao Beijing University of Chinese Medicine P.R.China 100102 Pharmaceutical Engineering and New Drug Development of Traditional Chinese Medicine(TCM)of Ministry of Education P.R.China 100102 Key Laboratory of TCM-information Engineering of State Administration of TCM Beijing P.R.China 100102 Beijing Key Laboratory for Basic and Development Research on Chinese Medicine Beijing P.R.China 100102

Near infrared chemical imaging(NIR-CI)combines conventional near infrared(NIR)spectros-copy with chemical imaging,thus provides spectral and spatial information simult *** could be utilized to visualize the spatial distribution of the ingredients in a *** data acquired using NIR CI instrument are hyperspectral data cube(hypercube)containing thousands of *** methodologies are necessary to transform spectral information into chemical *** least squares(PLS)method was performed to extract chemical information of chlorpheniramine maleate in pharmaceutical formulations.A series of samples which consisted of different CPM concentrations(w/w)were compressed and hypercube data were *** spectra extracted from the hypercube were used to establish the PLS model of *** results of the model were R^(2)_(val)0.981,RMSEC 0.384%,RMSECV 0.483%,RMSEP 0.631%,indicating that this model was reliable.

关键词： Near infrared chemical imaging partial least squares regression assessment of distributional homogeneity chlorpheniramine maleate

Decoding psychosis:from national genome project to national brain project

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General Psychiatry 2022年第4期35卷 214-223页

作者： Liya Sun manfei xu Yongyong Shi Yifeng xu Jinghong Chen Lin He Shanghai Mental Health Center Editorial Office Shanghai Jiao Tong University School of MedicineShanghaiChina Bio-X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric DisordersMinistry of EducationShanghai Jiao Tong UniversityShanghaiChina Shanghai Key Laboratory of Psychotic Disorders Shanghai Mental Health CentreShanghai Jiao Tong University School of MedicineShanghaiChina

The mind has puzzled humans for centuries,and its disorders,such as psychoses,have caused tremendous ***,relatively recent biotechnological breakthroughs,such as DNA technology and neuroimaging,have empowered scientists to explore the more fundamental aspects of *** searching for psychosis-causing genes to imaging the depths of the brain,scientists worldwide seek novel methods to understand the mind and the causes of its *** article will briefly review the history of understanding and managing psychosis and the main findings of modern genetic research and then attempt to stimulate thought for decoding the biological mechanisms of psychosis in the present era of brain science.

关键词： breakthrough sis psycho

Estimation of multivariate detection limits of four quality parameters in licorice using MEMS–NIR spectrometry coupled with two sampling accessories

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Journal of Innovative Optical Health Sciences 2015年第5期8卷 1-10页

作者： Zhisheng Wu Xinyuan Shi Na Zhao Yanling Pei manfei xu Luwei Zhou Yang Li Yanjiang Qiao Beijing University of Chinese Medicine P.R.China 100102 Beijing Key Laboratory for Basic and Development Research on Chinese Medicine Beijing P.R.China 100102 Key Laboratory of TCM-information Engineer of State Administration of TCM Beijing P.R.China 100102

In this work,multivariate detection limits(MDL)estimator was obtained based on the microelectro-mechanical systems–near infrared(MEMS–NIR)technology coupled with two sampling accessories to assess the detection capability of four quality parameters(glycyrrhizic acid,liquiritin,liquiritigenin and isoliquiritin)in licorice from di®erent geographical regions.112 licorice samples were divided into two parts(calibration set and prediction set)using Kennard–Stone(KS)*** quality parameters were measured using high-performance liquid chromatography(HPLC)method according to Chinese pharmacopoeia and previous *** MEMS–NIR spectra were acquired from¯ber optic probe(FOP)and integrating sphere,then the partial least squares(PLS)model was obtained using the optimum processing *** indicators have been utilized to assess the PLS model *** assessment using chemometrics indicators is based on relative mean prediction error of all concentration levels,which indicated relatively low sensitivity for low-content analytes(below 1000 parts per million(ppm)).Therefore,MDL estimator was introduced with alpha error and beta error based on good prediction characteristic of low concentration *** result suggested that MEMS–NIR technology coupled with fiber optic probe(FOP)and integrating sphere was able to detect minor *** result further demonstrated that integrating sphere mode(i.e.,MDL0:05;0:05,0.22%)was more robust than FOP mode(i.e.,MDL0:05;0:05,0.48%).In conclusion,this research proposed that MDL method was helpful to determine the detection capabilities of low-content analytes using MEMS–NIR technology and successful to compare two sampling accessories.

关键词： Near-infrared spectrometer multivariate detection limits sampling accessories licorice partial least squares regression

Guidance for use of weights: an analysis of different types of weights and their implications when using SAS PROCs

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General Psychiatry 2019年第1期32卷 49-55页

作者： Sabrina Richardson Tuo Lin Yangyi Li Xiaohui Niu manfei xu Valerie Stander Xin M Tu The Henry M.Jackson Foundation for the Advancement of Military Medicine Inc BethesdaMarylandUnited States Military Population Health Naval Health Research CenterSan DiegoCaUnited States Clinical and Translational Research Institute University of California San DiegoSan DiegoCaliforniaUSA School of Mathematical and Statistical Sciences Clemson UniversityClemsonSouth CarolinaUSA College of Informatics Huazhong Agriculture UniversityWuhanChina Shanghai Mental Health Center Medical CollegeShanghai Jiao Tong UniversityShanghaiChina

SAS and other popular statistical packages provide support for survey data with sampling weights. For example, PROC MEANS and PROC LOGISTIC in SAS have their counterparts PROC SURVEYMEANS and PROC SURVEYLOGISTIC to facilitate analysis of data from complex survey studies. On the other hand, PROC MEANS and many other classic SAS procedures also provide an option for including weights and yield identical point estimates, but different standard errors (SEs), as their corresponding survey procedures. This paper takes an in-depth look at different types of weights and provides guidance on use of different SAS procedures.

关键词： Guidance use of weights analysis

Post-hoc power analysis:a conceptually valid approach for power based on observed study data

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General Psychiatry 2022年第4期35卷 266-272页

作者： Natalie E Quach Kun Yang Ruohui Chen Justin Tu manfei xu Xin M Tu Xinlian Zhang Division of Biostatistics and Bioinformatics Herbert Wertheim School of Public Health and Human Longevity ScienceUC San DiegoLa JollaCaliforniaUSA Department of Orthopedics Emory HealthcareEmory UniversityAtlantaGeorgiaUSA Shanghai Mental Health Center Shanghai Jiao Tong University School of MedicineShanghaiChina

Power analysis is a key component of planning prospective studies such as clinical ***,some journals in biomedical and psychosocial sciences request power analysis for data already collected and analysed before acceptingmanuscripts for *** have raised concerns about the conceptual basis for such post-hoc power *** recently,Zhang et al showed by using simulation studies that such power analyses do not indicate true power for detecting statistical significance since post-hoc power estimates vary in the range of practical interests and can be very different from the true *** the other hand,journals'request for information about the reliability of statistical findings in a manuscript due to small sample sizes is justified since the sample size plays an important role in the reproducibility of statistical *** problem is the wording of the journals'request,as the current power analysis paradigm is not designed to address journals'concerns about the reliability of the statistical *** this paper,we propose an alternate formulation of power analysis to provide a conceptually valid approach to the journals'wrongly worded but practically significant concern.

关键词： power approach sizes

面向教材文本智能改编的教师语料库素养及实践应用

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外语界 2023年第3期 23-30页

作者：金檀李芷莹徐曼菲唐洁仪华南师范大学外国语言文化学院广东广州510631

教材文本智能改编主要包括机器定级后教师改编、机器标注后教师改编、机器替换后教师改编三种范式,每种范式都有各自的适用方法与应用工具。本文介绍了智能改编的三种范式,并结合语料库知识、语料库技术操作技能与语料库教学应用技能三... 详细信息

教材文本智能改编主要包括机器定级后教师改编、机器标注后教师改编、机器替换后教师改编三种范式,每种范式都有各自的适用方法与应用工具。本文介绍了智能改编的三种范式,并结合语料库知识、语料库技术操作技能与语料库教学应用技能三个维度,阐释每种范式所需的教师语料库素养。文章进而通过在职外语教师培训案例,探讨了提升教师语料库素养及智能改编能力的可行路径。

关键词：教材文本智能改编语料库素养在职教师培训

Rapid analysis of dyed safflowers by color objectification and pattern recognition methods

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Journal of Traditional Chinese Medical Sciences 2016年第4期3卷 234-241页

作者： manfei xu Shengyun Dai Zhisheng Wu Xinyuan Shi Yanjiang Qiao Beijing University of Chinese Medicine Beijing 100102China Department of Pharmacy The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Beijing Key Laboratory for Basic and Development Research on Chinese Medicine BeijingChina Key Laboratory of TCM-information Engineer of State Administration of TCM BeijingChina

Objective:Rapid discrimination of three classes of safflowers,dyed safflower,adulterated safflower,and pure safflower using computer vision and image processing ***:A low cost computer vision system(CVS)was designed to measure the color of safflowers in the RGB(red,green,blue),L^*a^*b^*,and HSV(hue,saturation,vale)color *** color moments in these three color spaces were extracted from the acquired images as color features of *** addition,five kinds of pigments that are commonly used to dye safflowers were identified by high-performance liquid chromatography as a *** recognition methods were investigated for rapid discrimination,including an unsupervised principal component analysis(PCA)algorithm and a supervised partial least squares discriminant analysis(PLS-DA)***:The mean error(e)between color values measured with the colorimeter and calculated with the CVS was 2.4%,with a high correlation coefficient(r)of *** result indicated that the established CVS was reliable for color estimation of *** PLS-DA model,which had a total accuracy of 91.89%,outperformed the PCA model in classifying pure,adulterated,and dyed ***:The color objectification is a promising tool for rapid identification of dyed and adulterated safflowers.

关键词： Safflower Coloration Adulteration Computer vision PCA PLS-DA